Dutse Journal of Pure and Applied Sciences最新文献

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Effects of Zinc supplementation on male reproductive function in night shift work model of chronic sleep deprivation 补锌对长期睡眠不足的夜班工作模型中男性生殖功能的影响
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.38
Shihabuddeen Muhammad, A. Salisu, Yusuf Tanko
{"title":"Effects of Zinc supplementation on male reproductive function in night shift work model of chronic sleep deprivation","authors":"Shihabuddeen Muhammad, A. Salisu, Yusuf Tanko","doi":"10.4314/dujopas.v10i2b.38","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.38","url":null,"abstract":"Modernization and industrialization have changed human lifestyle with night shift work (NSW) becoming necessary part of regular  working hours. NSW is invariably associated with sleep deprivation (SD). Coincidentally, there is remarkable decline in fertility rates in  these modern societies, which is believed to be due to lifestyle modifications. NSW model of SD, was therefore created to study its effects on male reproductive functions and role of concomitant Zinc supplementation on those effects. Twenty four (24) male Wistar rats (aged  12- 14 weeks) were equally divided into three groups; Control, NSW and NSWZ models. NSW and NSWZ models were subjected to SD for  12 hours (07:00am – 07:00pm) using Modified Multiple Platform Method (MMPM) every day for the 56 days of the study. Each rat received  either distilled water (1ml/animal/day) for Control and NSW models, or Zinc sulphates (5mg/animal/day) for NSWZ model, by  gavage daily respectively. Testicular tissue Malondialdehyde (MDA) and Total Antioxidant Capacity (TAC), male reproductive hormones  (FSH, LH, Testosterone and Estradiol) and Sperm parameters (sperm count, morphology and motility) were evaluated and statistically  compared. Sleep deprivation in NSW model resulted in significant (p<0.05) increase in testicular tissue MDA, serum FSH and significant  (p<0.05) decrease in TAC, serum Testosterone, serum Estradiol, sperm count and percentage of sperm with active progressive motility  (APM) compared to the control. Concomitant Zinc supplementation significantly (p<0.05) increases testicular tissue TAC, serum Estradiol  and significantly (p<0.05) decreases testicular tissue MDA and serum FSH. The NSW model of Sleep deprivation negatively affects male  reproductive functions, while concomitant Zinc supplementation ameliorates some of these negative effects. ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical and Mosquito Repellent activities of Citrus sinensis, Citrus reticulate and Citrus limon Leaves 柑橘叶、网纹柑橘叶和柠檬叶的植物化学成分和驱蚊活性
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.3
B.D. Yakasai, A. Yunusa, M.I. Fatima, A. Sani, A. Salisu, M. Aminu, M.M. Namadina, S.I. Maryam
{"title":"Phytochemical and Mosquito Repellent activities of Citrus sinensis, Citrus reticulate and Citrus limon Leaves","authors":"B.D. Yakasai, A. Yunusa, M.I. Fatima, A. Sani, A. Salisu, M. Aminu, M.M. Namadina, S.I. Maryam","doi":"10.4314/dujopas.v10i2b.3","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.3","url":null,"abstract":"Given their primary role as the cause of numerous vector-borne illnesses, mosquitoes constitute a major contributor to Nigeria's disease  burden. In an effort to slow the disease's spread, a variety of techniques are currently being employed to manage the vector. Plants are  considered as a rich source of phytochemical and they may be an alternative source of mosquito control agents in mosquito control program due to their excellent larvicidal and adulticidal properties. The study was aimed to evaluate the phytochemical and repellent  activities of Citrus sinensis, Citrus reticulate and Citrus limon leaves. The extracts were subjected to phytochemical screening in order to  identify the phytochemical constituents of the plant species using standard methods. The extracts were evaluated for its repellent activities against female Anopheles using the human – bait technique. The results of phytochemical screening showed the presence of  alkaloids, phenols, flavonoids, tannins and carbohydrate. Concentrations of plant extracts (2.0, 3.0 and 4.0 mg/mL) used exhibited  repellent activity against female Anopheles mosquitoes which indicates that the methanol extract of Citrus reticulate was more effective  in exhibiting a repellency action against the mosquito tested when compared to the control. The result showed that the selected plant  extracts had repellent activity against Anopheles mosquitoes tested with different complete protection time (CPT) when compared with  the control. The percentage repellency of Citrus sinensis (36%), Citrus reticulate (20%) and Citrus limon (35%) It has also showed low  biting activity compare to control with highest biting deterrence recorded for the selected concentrations.  ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance Evaluation of a Modified Mobile Melon Depodding Machine 改良型移动甜瓜脱壳机的性能评估
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.14
A. A. Aderinlewo, J.O. Oshoneye, O.B. Adebowale, P. O. Omotainse, B.O. Oresanya
{"title":"Performance Evaluation of a Modified Mobile Melon Depodding Machine","authors":"A. A. Aderinlewo, J.O. Oshoneye, O.B. Adebowale, P. O. Omotainse, B.O. Oresanya","doi":"10.4314/dujopas.v10i2b.14","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.14","url":null,"abstract":"Melons, a vital crop rich in proteins and oils, are predominantly cultivated in West Africa and used extensively in local cuisines. This study  focused on the performance evaluation of a modified mobile melon depodding machine, designed to overcome the limitations of  stationary, electricity-dependent machines through enhanced mobility and a petrol engine. The machine's efficiency was assessed at various operating speeds (230, 255, 272, 287, and 310 rpm), examining metrics such as seed and pulp discharge efficiencies, depodding  efficiency, material discharge efficiency, and overall efficiency. Results revealed that seed discharge efficiency ranged between 66.50%  and 70.61%, and pulp discharge efficiency increased with speed, reaching up to 90.18%. The optimal performance was noted at 272 rpm with a depodding efficiency of 89.05% and an overall efficiency of 69.10%. These findings underscore the modified machine's capacity to  enhance melon seed extraction processes significantly, providing a robust solution for agricultural productivity in areas lacking electrical  infrastructure. ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Embedded Communication System for Monitoring and Authenticating Transactions via Proxy on Automatic Teller Machine (ATM) 通过代理监控和验证自动取款机 (ATM) 交易的嵌入式通信系统
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.2
Ibilade Abdurrasaq Ibiyemi, Haruna Musa, Jelilat Olusola Yusuf
{"title":"Embedded Communication System for Monitoring and Authenticating Transactions via Proxy on Automatic Teller Machine (ATM)","authors":"Ibilade Abdurrasaq Ibiyemi, Haruna Musa, Jelilat Olusola Yusuf","doi":"10.4314/dujopas.v10i2b.2","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.2","url":null,"abstract":"This paper reports the development of a secured system which allows the registered customer of a bank to monitor and authorize  transaction via proxy on ATM. The system utilizes Atmel AVR microcontroller and communication modem as its controlling device.  Microsoft Windows 8 was used as an operating system platform in the host PC for the implementation phase, with Object oriented C programming language in Microsoft Visual Studio 2013 being the front end development and MSSQL server 2012 as back end. A Bank  customer’s cell phone is used as a token for withdrawal transaction to be made in the account. Transaction could be made without  disclosing personal identification number (PIN) to the nominee because the account owner authorizes the machine by sending the PIN  and the amount to be withdrawn through his phone even in a remote area as far as there is a communication network. The application  evaluation of the system was based on security of user PIN for transaction via proxy, ability of account or debit card owner to validate  transaction on the ATM in absentia and average authentication time in comparison to the maximum authentication time allowed on the  system. The ability to recognize user’s phone number shows the security and reliability of the proposed system for ATM users’  authentication. Results also showed that for a successful transaction, the proposed system allowed an average transaction time of 47.58  seconds through SMS.  ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extraction and Quantification of Oil Extracted from Seeds of Underexploited Tropical Plants in Akwa Ibom State, Nigeria 从尼日利亚阿夸伊博姆州未充分开发的热带植物种子中萃取的油脂的提取和定量
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.32
E.E. Akpan, S.M. Sam, E.A. Akpan, J.E. Okon, O.G. Okon
{"title":"Extraction and Quantification of Oil Extracted from Seeds of Underexploited Tropical Plants in Akwa Ibom State, Nigeria","authors":"E.E. Akpan, S.M. Sam, E.A. Akpan, J.E. Okon, O.G. Okon","doi":"10.4314/dujopas.v10i2b.32","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.32","url":null,"abstract":"Oil was extracted from seeds of Coula edulis, Dacryodes edulis, Garcinia kola and Cola lepidota, using n-hexane, chloroform and a  fraction of n-hexane and chloroform (1:1) as extracting solvents. The extraction was carried out at a temperature of 60oC. Using n- hexane as the extracting solvent, 42.5%, 40.1%, 24.63% and 35.73% were the yields of oil extracted from C. edulis, D. edulis, G. kola and C. lepidota respectively. Values recorded for chloroform-extracted oil were 28.7%, 25.4%, 10.83% and 21.93% respectively. Using a fraction of  n-hexane and chloroform (1:1), the experimental seeds had percentage oil yield of 31.4, 27.92, 13.53 and 24.63 respectively. The results  show that C. edulis and D. edulis had high oil content, when compared with G. kola and C. lepidota. These results suggest that n-hexane  remains a veritable solvent for extraction of oil from seeds of tropical plants.  ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141831130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heavy Metals Contamination Awareness Among Leafy Vegetables Consumers in Kano, Nigeria 尼日利亚卡诺叶菜类消费者对重金属污染的认识
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.33
N. Abdullahi, E. Igwe, M. Dandago, Hauwa Ladi Yusuf, Hauwa Dauda Adamu
{"title":"Heavy Metals Contamination Awareness Among Leafy Vegetables Consumers in Kano, Nigeria","authors":"N. Abdullahi, E. Igwe, M. Dandago, Hauwa Ladi Yusuf, Hauwa Dauda Adamu","doi":"10.4314/dujopas.v10i2b.33","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.33","url":null,"abstract":"The toxicity and accumulation behaviour of heavy metals (HMs) make them a potential danger not only to plants but also to humans.  Heavy metals can have their way into humans through the consumption of contaminated foods. Understanding public perception of HM  contamination will guide the concerned authorities in curtailing the risks associated with their consumption in foods. The research aim to  assess the level of consumers' awareness of the presence of heavy metals (HMs) in commonly consumed leafy vegetables (amaranth,  lettuce and cabbage) in Kano and the dangers associated with the consumption of HM-contaminated leafy vegetables. Data was  gathered through oral interviews; 86 leafy vegetable habitual consumers were interviewed in the Kano metropolis. Information gathered  includes demography of the respondents, vegetable sources, HM contamination awareness in irrigation water and vegetables, awareness  of dangers associated with the consumption of HM-contaminated vegetables, awareness of possible contamination from  other foods and activities that can worsen HM-related health problems in humans. The results revealed that over 91 % of the respondents  consume all three types of vegetables (amaranth, lettuce and cabbage). The level of HMs contamination awareness among vegetable consumers in Kano is poor, the possibility of having HMs contamination in vegetables is known by only 23.26 % and only 5.58 %  know that HMs contamination can cause health problems such as kidney failure and cancers. Education level does not influence the  consumers' awareness of vegetable-heavy metal contamination.","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":"219 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141828268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing The Impact of Cryptocurrency on Nigeria’s Digital Economic Advancement 评估加密货币对尼日利亚数字经济发展的影响
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.19
M. Umar, Sadiq Aliyu Ahmad, Abdulhakeem Abdulazeez, Asma'u Shehu, Bello Alhaji Buhari, Ziya’u Bello
{"title":"Assessing The Impact of Cryptocurrency on Nigeria’s Digital Economic Advancement","authors":"M. Umar, Sadiq Aliyu Ahmad, Abdulhakeem Abdulazeez, Asma'u Shehu, Bello Alhaji Buhari, Ziya’u Bello","doi":"10.4314/dujopas.v10i2b.19","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.19","url":null,"abstract":"Cryptocurrency is a type of virtual money whereby transactions are conducted and validated using a decentralized system that employs  cryptography. This paper discusses the concept of cryptocurrency by highlighting some of the key features in which are decentralization  and the use of cryptography. It further discusses the concept of digital economy which is the economy that focused on digital technologies. Benefits and some drawbacks of the economy are briefly highlighted. Next, using an analysis of the National Digital  Economy Policy and Strategy (2020–2030), the article discusses Nigeria's digital economy. Eight pillars were defined under the policy to  hasten the growth of the Nigerian digital economy. The consequences of cryptocurrencies on Nigeria's move toward a digital economy  were finally examined in the study. ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141828301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physio-Anatomical Potentials of Some Vegetable Species for Atmospheric Humidification and Purification in Ojo Area, Lagos, Nigeria 尼日利亚拉各斯奥霍地区一些蔬菜品种用于大气加湿和净化的生理解剖学潜力
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.20
K. T. Omolokun, O. Oluwa, O. J. Sharaibi, A. W. Ojewumi, O. M. Keshinro, O. S. Oyetunji, Rasheed Abayomi Anofiu, Gbemisola Ifeoluwa Fernandez, M. M. Mamudu
{"title":"Physio-Anatomical Potentials of Some Vegetable Species for Atmospheric Humidification and Purification in Ojo Area, Lagos, Nigeria","authors":"K. T. Omolokun, O. Oluwa, O. J. Sharaibi, A. W. Ojewumi, O. M. Keshinro, O. S. Oyetunji, Rasheed Abayomi Anofiu, Gbemisola Ifeoluwa Fernandez, M. M. Mamudu","doi":"10.4314/dujopas.v10i2b.20","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.20","url":null,"abstract":"The stomatal features of plant species have capacity to release water vapour into the atmosphere. Therefore, the correlation between the  stomatal features and transpiration rate in six vegetable species: Amaranthus cruentus, Capsicum annuum, Celosia argentia,  Corchorus olitorius, Solanum lycopersicum and Talinum fruticosum were examined for their atmospheric humidification and purification.  The leaf epidermal layers were isolated using nail polish; and were observed under the light microscope to examine their stomatal  features. The transpiration rate was carried out using the cobalt chloride method. Results obtained reveal that all the six species are  amphistomatic. The stomatal complex types observed are anisocytic, paratetracytic, staurocytic, brachyparatetracytic, anomotetracytic  and anomocytic. The stomatal density ranged from 52.63 to 153.22 mm-2 on both leaf surfaces. The stomatal index ranged from 31.34 to  71.42% on both leaf surfaces. This investigation showed that stomatal features such as amphistomatic leaf nature, stomatal complex  types (i.e. anomocytic, anomotetracytic, brachyparatetracytic, staurocytic, paratetracytic and anisocytic) with many subsidiary cells, high  stomatal density and high stomatal index were responsible for the high transpiration rate of the studied species. Hence, Capsicum  annuum humidifies the atmosphere most (8.85 × 10-6), followed by Solanum lycopersicum (8.83 × 10-6), Celosia argentia (7.29 × 10-6), Amaranthus cruentus (6.85 × 10-6), Talinum fruticosum (5.42 × 10-6), and the least was Corchorus olitorius (5.11 × 10-6 mol. M-2s -1 ).  Conclusively, the stomatal traits showed positive correlations with transpiration rates, thereby enhancing atmospheric humidification and  climate change mitigation (i.e. atmospheric purification).  ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modelling Nigeria Rainfall Data Using Exponential Family of Distribution: A Comparative Study 使用指数分布族建立尼日利亚降雨数据模型:比较研究
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.15
E. S. Oguntade, Timileyin K. Babalola, D. Oladimeji
{"title":"Modelling Nigeria Rainfall Data Using Exponential Family of Distribution: A Comparative Study","authors":"E. S. Oguntade, Timileyin K. Babalola, D. Oladimeji","doi":"10.4314/dujopas.v10i2b.15","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.15","url":null,"abstract":"In response to the growing concern about climate change, the study focuses on rainfall, a complex and challenging meteorological  variable to predict compared to temperature. This research introduces an innovative approach to model rainfall data, leveraging  probability distributions from the exponential family. The study utilizes secondary data encompassing monthly rainfall measurements in  millimeters (mm) spanning from 1986 to 2020, obtained from the Nigeria Meteorological Agency (NiMET) – covering a span of thirty-five  years. To identify the most suitable distribution, various model efficiency criteria, including log-likelihood, Kolmogorov-Smirnov test,  Cramer-Von Mises, Anderson Darling, and Akaike Information Criterion (AIC), are employed. The analysis highlights the Weibull  distribution as the most fitting model, exhibiting the highest likelihood value, along with the lowest values for the Kolmogorov-Smirnov  test, Cramer-Von Mises, Anderson Darling, and AIC. For six States under consideration: Abuja, Lagos, Edo, Kebbi, Taraba, and Enugu, the  study establishes the Weibull distribution as the superior choice. Notable log-likelihood and AIC values for each location reinforce its suitability for modeling rainfall data in Nigeria. Specifically, the log-likelihood and AIC values for Abuja are 1910.155 and 3824.309,  respectively, and similar trends are observed across the other locations. Consequently, the study strongly recommends the adoption of  the Weibull distribution as the preferred model for rainfall data modeling in Nigeria. Additionally, it encourages further research into rainfall data modeling employing the Weibull distribution within the context of time series models, both with and without seasonality,  utilizing the well-established Box-Jenkins methodology ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Co-administration of Moringa oliefera Leaf Tea with Standard Drug on Diabetic and Hypertensive Co-morbidity Patients Moringa oliefera 叶茶与标准药物合用对糖尿病和高血压并发症患者的影响
Dutse Journal of Pure and Applied Sciences Pub Date : 2024-07-17 DOI: 10.4314/dujopas.v10i2b.28
M. O. Lambe, A. I. Adedo, Q.O. Nurudeen, A. O. Elemosho
{"title":"Effects of Co-administration of Moringa oliefera Leaf Tea with Standard Drug on Diabetic and Hypertensive Co-morbidity Patients","authors":"M. O. Lambe, A. I. Adedo, Q.O. Nurudeen, A. O. Elemosho","doi":"10.4314/dujopas.v10i2b.28","DOIUrl":"https://doi.org/10.4314/dujopas.v10i2b.28","url":null,"abstract":"Treatments of diabetes and hypertension have remained a great challenge due to complications of toxicities and drug resistance  associated with the chemotherapeutic regimens. Hence the need to explore the use of supplements in the management of diabetic  patients. This study aimed to evaluate the effects of Moringa oleifera leaf tea (MOT) supplements on the glucose and haematological  parameters in diabetes and hypertension co-morbidity patients. Fifty (50) patients of either sex diagnosed with the comorbidity of  diabetes and hypertension were randomly assigned into five groups each consisting of ten patients (n=10) each. Group 1 served as the  positive control, Group 2 as the negative control, Group 3 received normal control treatment plus MOT , Group 4 was treated with a  reference drug, and Group 5 received the reference drug in combination with MOT. Administration was done for 14 days and thereafter,  blood samples were collected for the assay of advanced glycation end product (AGEs), Advanced Oxidation Protein Product (AOPP),  Glucose Index (Random, fasting and post prandial blood sugars) and haematological indices. The result revealed a significant decrease  (p<0.01) in the level of AGEs and AOPP among patients treated with MOT compared to patients served with standard drug only and  groups treated with standard drugs and control. There was a significant (p<0.01) reduction in the haematological parameters of all the  groups treated with the standard drugs. However, there was a significant increase in the haematological parameters of the groups co- administered with MOT when compared with the control groups with only standard drugs. In conclusion, co-administration of M. oleifera  leaf tea to patients suffering from diabetes-hypertension comorbidity treatment regimens can mitigate the adverse effects of the drugs  by the reduction of glycemic parameters while improving the haematological parameters.  ","PeriodicalId":213779,"journal":{"name":"Dutse Journal of Pure and Applied Sciences","volume":" 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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