Saudi Journal of Kidney Diseases and Transplantation最新文献_第7页

Prolonged Clinical Course and Unexpected Outcome of Postinfectious Glomerulonephritis in an 11-Year-Old Boy. 1例11岁男童感染后肾小球肾炎的临床病程延长及意外结局。

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_483_21

Sufia Husain, Raghad Bokhari, Tariq AlJohani, Adi Alherbish, Syed Amir Ahmad

引用次数: 0

A Prospective Single-center Study Assessing the Immunogenicity of Oxford-AstraZeneca Vaccine in Maintenance Hemodialysis Patients. 一项评估牛津-阿斯利康疫苗在维护性血液透析患者中的免疫原性的前瞻性单中心研究

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_606_21

Sandeep Deshmukh, Hari Shankar Meshram, Subho Banerjee, Vivek B Kute, Sanshriti Chauhan, Ruchir Dave, Himanshu Patel

{"title":"A Prospective Single-center Study Assessing the Immunogenicity of Oxford-AstraZeneca Vaccine in Maintenance Hemodialysis Patients.","authors":"Sandeep Deshmukh, Hari Shankar Meshram, Subho Banerjee, Vivek B Kute, Sanshriti Chauhan, Ruchir Dave, Himanshu Patel","doi":"10.4103/sjkdt.sjkdt_606_21","DOIUrl":"10.4103/sjkdt.sjkdt_606_21","url":null,"abstract":"There is a definite paucity of data about the safety and immunogenicity of the Oxford-AstraZeneca vaccine among patients with maintenance hemodialysis (MHD). We aimed to assess the humoral response following this vaccine in a single center of India. In this prospective study, a total of 31 MHD cases were recruited and analyzed. The response was compared with a control group composed of 23 health-care workers. All participants had received two doses of the Oxford-AstraZeneca (COVISHIELD) vaccine. The serology testing was done with severe acute respiratory syndrome coronavirus 2 spike protein antibody assay using indirect chemiluminescence immunoassay after 1 month of the second dose. A cutoff of 15 arbitrary unit (AU)/mL was considered a positive seropositive response. The median age of the patients was 44 (36-52.5) years. Five cases were pretransplant and three were posttransplant with graft failures. Fourteen (45.1%) cases had a 4-week gap between the two doses whereas 17 (54.9%) had an 8-week gap. The median (interquartile range) antibody levels of the MHD and control groups were 400 (315-400) and 398 (367-400) AU/mL, respectively (P = 0.37). All MHD and control groups developed a positive seroresponse. There was no difference in antibody response concerning age, sex, dialysis vintage, or dosing schedule. However, there was a significant difference in the level of antibody response for the MHD cases on immunosuppressive drugs (P = 0.02). The humoral response in maintenance dialysis patients with Oxford-AstraZeneca was comparable to general patients in our report, and immunosuppressive medications were associated with a decreased seroresponse.","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"35 1-6","pages":"142-150"},"PeriodicalIF":0.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145695769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence-Based Clinical Practice Guidelines for the Assessment and Management of Chronic Kidney Disease: A Systematic Review and Quality Assessment Using the AGREE II Instrument. 慢性肾脏疾病评估和管理的循证临床实践指南：使用AGREE II工具的系统评价和质量评估

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_127_22

Mohamed Ali Babiker Mohamed, Ahmed M El-Malky, Yasser S Amer, Wael Ahmed Abdelwahab Abdelkarim, Mohamed Abdulmonem Salih Aabdeen, Tarig Hassan Elobid Ahmed, Hassan H H Sarsour, Munirah Mohammed Mosa, Abdulrahman Ali M Khormi, Mohammed Aali S Alghamdi, Rakan I Nazer

{"title":"Evidence-Based Clinical Practice Guidelines for the Assessment and Management of Chronic Kidney Disease: A Systematic Review and Quality Assessment Using the AGREE II Instrument.","authors":"Mohamed Ali Babiker Mohamed, Ahmed M El-Malky, Yasser S Amer, Wael Ahmed Abdelwahab Abdelkarim, Mohamed Abdulmonem Salih Aabdeen, Tarig Hassan Elobid Ahmed, Hassan H H Sarsour, Munirah Mohammed Mosa, Abdulrahman Ali M Khormi, Mohammed Aali S Alghamdi, Rakan I Nazer","doi":"10.4103/sjkdt.sjkdt_127_22","DOIUrl":"10.4103/sjkdt.sjkdt_127_22","url":null,"abstract":"Clinical practice guidelines (CPGs) based on evidence and expert opinions ensure that patients with chronic kidney disease (CKD) receive the most up to date care. We aimed to assess and evaluate the most recent and approved international CPGs and compare them via the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument. Four independent reviewers appraised the selected guidelines with the AGREE II instrument. We considered five eligible CPGs for critical appraisal: the National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI) CPGs for CKD, the National Institute for Health and Care Excellence (NICE) guidelines for assessing and managing CKD, the Academy of Nutrition and Dietetics' CKD evidence-based nutrition practice guidelines, the CPGs of the Ministry of Public Health in Qatar (MOPH/QA), and the Scottish Intercollegiate Guidelines Network's guidelines for the diagnosis and management of CKD. The overall assessments of three CPGs (NICE, NKF-K/DOQI, and MOPH/QA) scored greater than 85%; the results were congruent with higher scores in the six AGREE II domains: 80%, 67%, and 86% for Domain 3; 47%, 43%, and 86% for Domain 5; and 60%, 48%, and 86% for Domain 6, respectively. Generally, the clinical recommendations were significantly better for the NICE CPGs. All evidence-based CPGs had relatively low methodological quality. The NICE CPGs demonstrated the highest quality, followed by the MOPH/QA and NKF-K/DOQI CPGs, and all five CPGs were recommended for use in practice but with improvements. Saudi Arabia has to formulate its own national CPGs for the diagnosis and management of CKD based on those published by the NICE.","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"35 1-6","pages":"80-97"},"PeriodicalIF":0.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145696179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal and Fetal Outcomes and Their Predictors in Renal Dysfunction in Pregnancy. 妊娠期肾功能不全的母胎结局及其预测因素。

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_52_22

Shakir Ahmad, Rudramani Swami, Kalpana Mehta, Sayed Salman Ali, Rakesh Bhadade, Rosemary D'Souza

{"title":"Maternal and Fetal Outcomes and Their Predictors in Renal Dysfunction in Pregnancy.","authors":"Shakir Ahmad, Rudramani Swami, Kalpana Mehta, Sayed Salman Ali, Rakesh Bhadade, Rosemary D'Souza","doi":"10.4103/sjkdt.sjkdt_52_22","DOIUrl":"10.4103/sjkdt.sjkdt_52_22","url":null,"abstract":"Renal disorders in pregnancy include pregnancy-related acute kidney injury (AKI) and pre-existing chronic kidney disease (CKD), which are risky for both the mother and the fetus. Here, we present the epidemiology and outcomes of pregnancy-related acute kidney injury and CKD in pregnancy at our tertiary care center. We studied the maternal and fetal outcomes of AKI and CKD in pregnancy. Pregnant females and women up to 6 weeks postpartum with AKI or CKD were included in the study; those aged <18 years were excluded. Of 70 cases, 55 had AKI, 10 had AKI and CKD, and 5 had CKD (two were at CKD Stage 5D). The mean age was 27.5 ± 5.4 years, and the mean gestational age was 28.6 ± 8.2 weeks. Sepsis was the most common cause of AKI, followed by pre-eclampsia (21/65). Of the mothers, 48 out of 68 recovered completely (two were already on maintenance hemodialysis), and 10 died. Twenty patients required hemodialysis, nine of whom recovered completely, one progressed to CKD, four became dependent on dialysis, and six died. Regarding the fetal outcomes, 28 were normal-term deliveries, seven were medically terminated, and 35 died. Hypertension, sepsis, metabolic acidosis, raised bilirubin, and the need for hemodialysis were significantly associated with poor maternal outcomes. Raised bilirubin was the only maternal factor significantly associated with poor fetal outcomes. AKI and CKD in pregnancy are associated with higher morbidity and mortality in both the mother and fetus; hence, the focus must be on prevention through regular antenatal checkups.","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"35 1-6","pages":"29-38"},"PeriodicalIF":0.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145696242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Lithium-associated Hyperparathyroidism in an Elderly Patient. 老年患者锂相关甲状旁腺功能亢进的治疗。

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_302_21

Arun Prabhahar, Jasmine Sethi, Ashwin Parihar, Neeraj Balaini

引用次数: 0

Empowerment Based on the Support System of Iran's Organ Procurement Centers in Identifying Organ Donors in Critical Wards of Hospitals Affiliated with Shahrekord University of Medical Sciences. 基于伊朗器官采购中心支持系统的授权在Shahrekord医科大学附属医院重症病房识别器官捐献者。

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_244_22

Hojjat Aallah Amiri, Majid Shirani, Jafar Moghadasi, Pantea Ramezannezad, Shahriyar Salehi Tali

{"title":"Empowerment Based on the Support System of Iran's Organ Procurement Centers in Identifying Organ Donors in Critical Wards of Hospitals Affiliated with Shahrekord University of Medical Sciences.","authors":"Hojjat Aallah Amiri, Majid Shirani, Jafar Moghadasi, Pantea Ramezannezad, Shahriyar Salehi Tali","doi":"10.4103/sjkdt.sjkdt_244_22","DOIUrl":"10.4103/sjkdt.sjkdt_244_22","url":null,"abstract":"Identifying potential cases of brain death is the first step of the organ donation process. The present study aimed to determine the effect of empowerment based on the Iranian OPUs supporting system (IROSS)on the knowledge, attitudes, and practices of intensive care nurses in identifying potential organ donors. In a quasi-experimental study, 80 nurses from the intensive care unit and emergency department of two hospitals affiliated with Shahrekord University of Medical Sciences were selected by convenience sampling and then randomly distributed into two groups, namely the intervention and control groups. The intervention group received IrOSS-based empowerment through workshops, lectures, role-playing, observation, and presence at the patients' bedside, and then, they were followed up for 2 months. Before and immediately after the intervention, as well as 2 months later, the knowledge and attitudes questionnaires and the practice checklist were completed by the two groups. Before the intervention, the mean score of knowledge, attitudes, and practices of the intervention group was not significantly different from that of the control group (P >0.05). However, immediately after the intervention and 2 months afterward, the statistical difference was positive (P <0.01), as the repeated measures analysis of variance showed an increasing trend in the mean score of knowledge, attitudes, and practices in three different situations in the intervention group (P <0.05). The empowerment of nurses using the IrOSS were effective in identifying potential organ donors.","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"35 1-6","pages":"65-79"},"PeriodicalIF":0.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145695920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lead Exposure and Kidney Damage among Artisans in Auto Mechanic Workshops in Ibadan, Southwestern Nigeria. 尼日利亚西南部伊巴丹市汽车修理厂工人的铅暴露和肾脏损伤。

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_479_20

Samuel Oluwole Ajayi, Yemi Raheem Raji, Obioma Uchendu, Kayode Adedapo, Babatunde Lawal Salako, Solomon Kadiri

{"title":"Lead Exposure and Kidney Damage among Artisans in Auto Mechanic Workshops in Ibadan, Southwestern Nigeria.","authors":"Samuel Oluwole Ajayi, Yemi Raheem Raji, Obioma Uchendu, Kayode Adedapo, Babatunde Lawal Salako, Solomon Kadiri","doi":"10.4103/sjkdt.sjkdt_479_20","DOIUrl":"10.4103/sjkdt.sjkdt_479_20","url":null,"abstract":"Environmental factors play a substantial role in causing chronic kidney disease, but only traditional risk factors such as hypertension, diabetes mellitus, and glomerulonephritis have received widespread attention. This study examined the role of environmental lead exposure in causing kidney disease among artisans in auto mechanic workshops in Nigeria. This was a crosssectional study involving auto mechanics in selected workshops in Ibadan. Sociodemographic details were obtained. Other details obtained included the period of exposure to lead or lead materials and occupational history. Serum lead levels, urinalysis, kidney function, and blood glucose were tested. Four hundred and twelve participants, mostly males (99%) participated. The mean and standard deviation serum lead level was 15.4 ± 7.8 μg/dL. The mean and standard deviation estimated glomerular filtration rate for all participants was 72.9 ± 36.7 mL/min. Serum lead levels correlated with eGFR (r = 0.396, P = 0.044) and microalbuminuria (r = 0.413, P = 0.042). The number of years working in painting correlated with microalbuminuria (r = 0.801, P = 0.0190). Most artisans working in auto mechanic shops in our study had serum lead levels of ≤25 μg/dL, and there was an association between working with iron and lead-containing metals and kidney disease, and serum lead levels were a risk for kidney damage.","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"35 1-6","pages":"13-19"},"PeriodicalIF":0.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145696176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicopathological Characteristics and Predictors of Poor Outcomes in Biopsy-Proven Acute Interstitial Nephritis. 活检证实的急性间质性肾炎的临床病理特征和预后不良的预测因素。

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_537_20

Zafirah Zahir, Asif Sadiq Wani, Narendra Krishnani, Amit Gupta

{"title":"Clinicopathological Characteristics and Predictors of Poor Outcomes in Biopsy-Proven Acute Interstitial Nephritis.","authors":"Zafirah Zahir, Asif Sadiq Wani, Narendra Krishnani, Amit Gupta","doi":"10.4103/sjkdt.sjkdt_537_20","DOIUrl":"10.4103/sjkdt.sjkdt_537_20","url":null,"abstract":"Acute interstitial nephritis (AIN) is an immune-mediated kidney injury. We studied its clinicopathological features, the role of corticosteroids, the outcomes, and the predictors of poor outcomes in biopsy-proven AIN. This was a 5-year retrospective, single-center observational cohort study of patients with biopsy-proven AIN. Of 2890 native renal biopsies, 61 (2.1%) had the features of AIN. The most common etiology was drug intake (27 patients), followed by infection-related AIN (14 patients), autoimmune conditions (six patients), malignancy (four patients), others (five patients), and unknown causes (four patients). Patients with autoimmune diseases were younger (P = 0.02), had a higher frequency of anemia (P = 0.004), and features of chronicity (P = 0.006). Hematuria (P = 0.004) and eosinophils (P = 0.05), and crystals in the tubules were mostly seen in drug-induced AIN. There was a significant difference in the recovery of patients receiving steroids within 1 week and 1 week after presentation. The predictors of poor outcomes were serum creatinine [hazard ratio (HR) = 1.4, P = 0.04)], an autoimmune etiology (HR = 3.2, P = 0.05), interstitial fibrosis or tubular atrophy (HR = 1.4, P = 0.04), and delayed treatment with corticosteroids (HR = 0.01, P = 0.04). Infections and ayurvedic medicines are important causes of AIN in India. The triad of eosinophils in the interstitium, oxalate crystals in the tubular epithelium, and red blood cells in the tubular lumen suggest drug-induced AIN. The initial time period is crucial, and we advocate using corticosteroids even before biopsy reports are available.","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"35 1-6","pages":"20-28"},"PeriodicalIF":0.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145695780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Contralateral Suppression of Otoacoustic Emissions, Middle Ear Mechanics, and Hearing in Renal Transplant Patients via Otoacoustic Emissions and Ear Mechanics. 通过耳声发射和耳力学评估肾移植患者对侧耳声发射、中耳力学和听力的抑制。

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_142_21

Isilay Oz, Ebru H Ayvazoglu Soy, C Burak Sayin, Levent N Ozluoglu, Mehmet Haberal

{"title":"Evaluation of Contralateral Suppression of Otoacoustic Emissions, Middle Ear Mechanics, and Hearing in Renal Transplant Patients via Otoacoustic Emissions and Ear Mechanics.","authors":"Isilay Oz, Ebru H Ayvazoglu Soy, C Burak Sayin, Levent N Ozluoglu, Mehmet Haberal","doi":"10.4103/sjkdt.sjkdt_142_21","DOIUrl":"10.4103/sjkdt.sjkdt_142_21","url":null,"abstract":"The stria vascularis, which is located in the cochlea of the inner ear, and the renal tubules contain similar anatomical, physiological, immunological, and pathological properties. Therefore, nephrotoxic drugs; electrolyte imbalances; and biochemical, immunological, osmotic, and vascular differences may affect the middle and inner ear and the central pathways. We evaluated the middle ear mechanisms, inner ear functions, and hearing thresholds of 30 renal transplant (RT) recipients (60 ears); 30 healthy volunteers (60 ears) served as the control group. All patients underwent an audiological assessment by means of pure-tone audiometry, otoacoustic emission (OAE), and contralateral suppression of transient-evoked OAE measurements. The mean follow-up after transplant was 6.8 ± 6.1 years (range: 1-20 years). Hearing for the four frequency averages between the two groups was significantly different (P = 0.002). When the cochlea's outer hair cells were evaluated, the signal-to-noise ratio was significantly lower at frequencies of 1000 and 1400 Hz in the RT group versus the control group (P <0.001 and P = 0.008, respectively). When frequency-specific suppressions were assessed, there was no significant suppression at any frequencies in the RT group, but significantly lower suppression was found at all frequencies in the control group (P <0.001 for all frequencies). These results support the presence of auditory dysfunction in RT recipients. Low levels of OAE support our conclusion that RT recipients are prone to cochlear dysfunction. Therefore, audiometric evaluations should be conducted before and after RT, and the recipients should be informed about possible otological involvement.","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"35 1-6","pages":"58-64"},"PeriodicalIF":0.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145696083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Causes of Obstructive Acute Kidney Injury: A Case Series. 梗阻性急性肾损伤的不寻常原因：一个病例系列。

IF 0.3

Saudi Journal of Kidney Diseases and Transplantation Pub Date : 2024-01-01 Epub Date: 2025-12-06 DOI: 10.4103/sjkdt.sjkdt_304_21

Rayees Yousuf Sheikh, Teerath Kumar Maheshwari, Sana Noman, Pradeep Hariharan, Krishanu Das

引用次数: 0