{"title":"Russell body duodenitis: a rare condition.","authors":"Helena González Sánchez, Gloria Meijide Santos, Cristina Fuente Díaz, Olegario Castaño Fernández","doi":"10.17235/reed.2024.10270/2024","DOIUrl":"10.17235/reed.2024.10270/2024","url":null,"abstract":"<p><p>Russell bodies are accumulations of immunoglobulins within hyperstimulated plasma cells of the intestinal mucosa associated with chronic inflammation of benign progression, but may be confused with lymphoplasmacytic lymphoma, MALT lymphoma, multiple myeloma, or \"signet-ring\" cells, among others. There are few cases of gastric involvement, but duodenal involvement is even rarer with less than 10 published cases. Endoscopic examination with quality biopsies and anatomopathologic analysis with immunohistochemistry are essential to make an adequate differential diagnosis with other more severe processes. In any case, the treatment is that of the underlying disease.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"165-166"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean Félix Piñerúa-Gonsálvez, Rosanna Del Carmen Zambrano-Infantino, Carmen Del Pozo, Sara Miranda Riaño, Ricardo Ruano, Luis Fernández-Salazar
{"title":"Secondary aorto-duodenal fistula: a diagnostic challenge in a patient with fever and anemia.","authors":"Jean Félix Piñerúa-Gonsálvez, Rosanna Del Carmen Zambrano-Infantino, Carmen Del Pozo, Sara Miranda Riaño, Ricardo Ruano, Luis Fernández-Salazar","doi":"10.17235/reed.2024.10358/2024","DOIUrl":"10.17235/reed.2024.10358/2024","url":null,"abstract":"<p><p>A 69-year-old male, three years post-endovascular exclusion for an abdominal aortic aneurysm, presented with asthenia and fever. An abdominal CT scan showed no gastrointestinal tract communications, abscess, or contrast extravasation. Tc-99m-HMPAO-labeled leukocytes scintigraphy with SPECT/CT revealed increased uptake on the posterior surface of the aortic graft, along with air bubbles in its right iliac limb. Upper gastrointestinal endoscopy was performed, revealing a duodenal ulcer in the transition between the second and third portions. The ulcer exhibited yellow graft tissue at its center. The patient underwent in situ reconstruction, involving the replacement of the infected prosthetic graft, and the duodenal defect was addressed through segmental resection and duodenojejunal anastomosis. Secondary aorto-duodenal fistula (SADF), a rare complication of vascular surgery, may arise from factors such as local infection or graft-bowel contact. SADF, often located in the duodenum, poses a high mortality risk, necessitating early diagnosis. Clinical presentation varies from significant upper gastrointestinal bleeding to obscured bleeding.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"160-161"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140102380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosing hilar cholangiocarcinoma: ERCP with cholangioscopy.","authors":"Jesús García-Cano, Francisco Domper","doi":"10.17235/reed.2025.11051/2024","DOIUrl":"10.17235/reed.2025.11051/2024","url":null,"abstract":"<p><p>Cholangiocarcinoma of the hepatic hilum represents a challenge in its diagnosis, in the palliation of the frequently associated jaundice, and in its treatment. Noninvasive imaging tests can offer a fairly accurate diagnostic approximation, but very often a histopathological diagnosis is necessary to exclude the so-called Klatskin-mimicking lesions, which can reach up to 20% in surgical series. ERCP is the most commonly used endoscopic procedure, both for tissue acquisition and for palliation of jaundice. Although probably underused, intraductal ultrasonography performed during ERCP can provide valuable information for the diagnosis of hilar cholangiocarcinoma. During ERCP, brush cytology and biopsy are performed to acquire tissue for histopathological confirmation of cholangiocarcinoma. The sensitivity of both methods alone is less than 50%. When biopsies are taken through a cholangioscope, the sensitivity is significantly increased. In this editorial we discuss a study by Alonso-Lárraga et al. published in the Spanish Journal of Gastroenterology. The highest sensitivity (77.4%) was obtained when 4 to 6 biopsies were taken with the SpyGlass cholangioscope. Direct visualization of lesions and the higher diagnostic yield of biopsies make ERCP with cholangioscopy the standard approach for patients with suspected perihilar cholangiocarcinoma.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":"117 ","pages":"125-128"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coexisting achalasia and leiomyoma misdiagnosed as a submucosal tumor, successfully treated by simultaneous peroral endoscopic myotomy and submucosal tunneling endoscopic resection in the same tunnel.","authors":"Yanyu Chen, Shan Gao, Deliang Liu, Hejun Zhou","doi":"10.17235/reed.2023.9736/2023","DOIUrl":"10.17235/reed.2023.9736/2023","url":null,"abstract":"<p><p>Peroral endoscopic myotomy (POEM) is a safe and effective method in the treatment of achalasia. Meanwhile, submucosal tunneling endoscopic resection (STER) is a common endoscopic method for the treatment of submucosal tumors (SMT) in the upper digestive tract. However simultaneous POEM and STER for coexisting achalasia and esophageal SMT is rarely reported. A 40-year-old woman underwent esophagoscopy after dysphagia and vomiting for 20 years. The protruding submucosal lesion with normal overlying mucosa was found in the lower part of the esophagus, nearing cardia. Considering the persistent swallowing discomfort and vomiting symptoms, the patient underwent esophageal manometry and barium esophagram, and was finally diagnosed as achalasia with esophageal submucosal tumor. Finally, POEM and STER were performed simultaneously on the patient in the same tunnel. The patient was followed up for 4 months without recurrence or complaints. We herein report a case of achalasia with esophageal leiomyoma who underwent POEM and STER in the same tunnel to remove the mass and relieve the symptoms.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"153-154"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9668737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sclerosing angiomatoid nodular transformation (SANT), a rare splenic tumor with increasing incidence.","authors":"Irene López Rojo, Ana Teijo Quintans, Raquel Saiz Martínez, Patricia Muñoz Hernández, Óscar Alonso-Casado","doi":"10.17235/reed.2023.9713/2023","DOIUrl":"10.17235/reed.2023.9713/2023","url":null,"abstract":"<p><p>SANT (sclerosing angiomatoid nodular transformation) tumor is a rare splenic tumor of unknown etiology and vascular lineage, first described in 2004. Most cases are asymptomatic, although cases of anemia or abdominal pain in association with growth have been described. Spontaneous ruptures have not been described. Radiologically it presents a radial pattern with centripetal filling in dynamic MRI, being a characteristic feature, but not pathognomonic. It may present hypermetabolism in PET-CT. Its incidence is increasing since its description as an independent clinical and histopathological entity, especially in the oncological patients follow-up. Due to its radiological resemblance to metastatic lesions and its growth despite being a vascular lesion, splenectomy is indicated following the principles of oncologic surgery until a definitive diagnosis is made. It presents a benign behavior, requiring neither treatment nor specific subsequent surveillance. Two diagnosed cases of SANT are presented, as well as a review of the clinical, radiological and histopathological characteristics of this little-known splenic lesion.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"148-150"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9982981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ogilvie, when medical and endoscopic treatment fail.","authors":"Isabel González Puente, Ana Belén Domínguez Carbajo, Sandra Borrego Rivas, Raisa Quiñones Castro","doi":"10.17235/reed.2024.10287/2024","DOIUrl":"10.17235/reed.2024.10287/2024","url":null,"abstract":"<p><p>Ogilvie syndrome is a functional disorder of colonic motility that causes acute and progressive dilation, which can lead to necrosis and perforation. Early diagnosis and management are essential to avoid serious complications. The case of a patient with Ogilvie syndrome refractory to medical and endoscopic treatment that required surgery is presented. This is a 68-year-old man with decreased level of consciousness and abdominal distension for 3 days. Last bowel movement 4 days ago. The data and tests appear in table 1. We are faced with a patient with neurological alteration and hemodynamically unstable secondary to complicated Ogilvie syndrome. After admission to the ICU, where a 2.5 mg bolus of neostigmine was administered, he was transferred to the ward. Despite 250 mg of intravenous erythromycin every 6 hours together with metoclopramide every 8 hours, high doses of polyethylene glycol and daily cleansing enemas and rectal catheterization, only a brief and mild improvement is achieved. Given the failure of conservative measures, colectomy was performed, achieving complete resolution. Ogilvie syndrome is a functional disorder1 that usually associates predisposing factors that impact intestinal motility 2 ; In our case: bedridden, the use of anticholinergics, hydroelectric alteration both due to the use of antidepressants and the creation of a third space secondary to colonic dilation and severe intestinal ischemia². In one third it is resolved by early correction of the triggering factors, adding neostigmine if necessary with high rates of effectiveness¹. In our case, a second bolus of neostigmine could have been administered or even as an infusion since greater efficacy has been demonstrated in this way given its short half-life². Electrolyte imbalance is a predictor of poor response to neostigmine, a factor that was associated with our patient 3. Colonic decompression and finally surgery are reserved as a last measure, being necessary in a very small percentage as in this case 1. As a preventive measure, the administration of 29.5 g of oral polyethylene glycol per day has been effective 4. Therefore, we should suspect Ogilvie syndrome in patients with predisposing factors who present acute dilation of the colon without mechanical obstruction, and although it usually resolves with medical and endoscopic treatment, we should not delay surgery to avoid complications.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"169-170"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucía Seoane Blanco, Brais Fernández Suárez, María Gómez Rivas, Andrea García Gómez
{"title":"Association of microscopic colitis and enteropathy due to olmesartan.","authors":"Lucía Seoane Blanco, Brais Fernández Suárez, María Gómez Rivas, Andrea García Gómez","doi":"10.17235/reed.2024.10258/2024","DOIUrl":"10.17235/reed.2024.10258/2024","url":null,"abstract":"<p><p>We report the case of a patient with severe chronic diarrhea. He was admitted on multiple occasions for this reason, with the cause remaining undetected. After obtaining a detailed medical history and performing several studies, the patient was diagnosed with microscopic colitis and enteropathy due to Olmesartan. In the literature, both diseases appear concurrently only in a few cases. Here we highlight the importance of conducting a comprehensive medical history and maintaining high clinical suspicion to avoid delays in the diagnosis of these uncommon pathologies, as well as unnecessary tests and empirical treatments.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"157-158"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atypical intrapapillary capillary loops in early-stage basaloid squamous cell carcinoma of the esophagus.","authors":"Qifei Tian, Fangli Men, Yuan Xu, Ailan Xian","doi":"10.17235/reed.2024.10223/2023","DOIUrl":"10.17235/reed.2024.10223/2023","url":null,"abstract":"<p><p>Basaloid squamous cell carcinoma of the esophagus (BSCCE) is rare and extremely difficult to identify at early stage.We herein presented a superficial depressed lesion at early stage.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"155-156"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139521809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EUS‑guided antegrade stenting for malignant jaundice following Roux‑en‑Y reconstruction: the treatment of multiple biliary strictures.","authors":"Hongfei He, Tingting Yu, Lichao Zhang, Yaoting Li, Yankun Hou, Jiao Tian, Senlin Hou","doi":"10.17235/reed.2024.10175/2023","DOIUrl":"10.17235/reed.2024.10175/2023","url":null,"abstract":"<p><p>Multiple malignant biliary strictures are rare, and the application of multiple stents can achieve better drainage. EUS-guided biliary drainage (EUS-BD) can be offered as an alternative technique when ERCP unsuccessful. We applied Endoscopic ultrasonic guided antegrade stenting technique to treat a case of multiple biliary strictures following Roux-en-Y reconstruction.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"164-165"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenpeng Huang, Yongbai Zhang, Yongshun Liu, Zhaonan Sun
{"title":"Immune cholangitis related to anti-programmed cell death and programmed cell death ligand agents for the treatment of intrahepatic cholangiocarcinoma.","authors":"Wenpeng Huang, Yongbai Zhang, Yongshun Liu, Zhaonan Sun","doi":"10.17235/reed.2024.10284/2024","DOIUrl":"10.17235/reed.2024.10284/2024","url":null,"abstract":"<p><p>Anti-programmed cell death (anti-PD1) and anti-programmed cell death ligand (anti-PDL1) agents represent a burgeoning field of immunotherapy with an expanding array of indications. In this report, we present the observation of a patient with intrahepatic cholangiocarcinoma exhibiting features of immune-related cholangitis.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"168"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}