{"title":"EUS‑guided antegrade stenting for malignant jaundice following Roux‑en‑Y reconstruction: the treatment of multiple biliary strictures.","authors":"Hongfei He, Tingting Yu, Lichao Zhang, Yaoting Li, Yankun Hou, Jiao Tian, Senlin Hou","doi":"10.17235/reed.2024.10175/2023","DOIUrl":"10.17235/reed.2024.10175/2023","url":null,"abstract":"<p><p>Multiple malignant biliary strictures are rare, and the application of multiple stents can achieve better drainage. EUS-guided biliary drainage (EUS-BD) can be offered as an alternative technique when ERCP unsuccessful. We applied Endoscopic ultrasonic guided antegrade stenting technique to treat a case of multiple biliary strictures following Roux-en-Y reconstruction.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"164-165"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenpeng Huang, Yongbai Zhang, Yongshun Liu, Zhaonan Sun
{"title":"Immune cholangitis related to anti-programmed cell death and programmed cell death ligand agents for the treatment of intrahepatic cholangiocarcinoma.","authors":"Wenpeng Huang, Yongbai Zhang, Yongshun Liu, Zhaonan Sun","doi":"10.17235/reed.2024.10284/2024","DOIUrl":"10.17235/reed.2024.10284/2024","url":null,"abstract":"<p><p>Anti-programmed cell death (anti-PD1) and anti-programmed cell death ligand (anti-PDL1) agents represent a burgeoning field of immunotherapy with an expanding array of indications. In this report, we present the observation of a patient with intrahepatic cholangiocarcinoma exhibiting features of immune-related cholangitis.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"168"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia García Gimeno, Alberto Alegre Delgado, Francisco Navarro Vicente, Andrea Marco Marqués, Jesús Manuel Santiago Sánchez
{"title":"Transverse colon volvulus in a young patient with wandering liver.","authors":"Natalia García Gimeno, Alberto Alegre Delgado, Francisco Navarro Vicente, Andrea Marco Marqués, Jesús Manuel Santiago Sánchez","doi":"10.17235/reed.2024.10245/2023","DOIUrl":"10.17235/reed.2024.10245/2023","url":null,"abstract":"<p><p>We present the case of a 26-year-old male patient with no history of interest who consulted the emergency department due to occlusive symptoms. Urgent CT showed the presence of a transverse colonic volvulus in the context of a heterotopic liver, located in the left hypochondrium. There were no clinical or radiological signs of perforation or ischemia, so urgent endoscopic decompression was performed with subsequent elective surgery with a favorable resolution of the condition. Transverse colonic volvulus is rare (<1%) and wandering liver is an exceptional predisposing factor, with less than a hundred published cases. In these patients, endoscopic decompression carries a risk of perforation with high recurrence rates, and surgical treatment should be considered. However, in this case, in the absence of severity criteria, decompressive colonoscopy was considered an urgent treatment and subsequent elective surgery with favorable results.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"170-171"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139723825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gastric ectopic pancreas with a pseudocyst.","authors":"Kazuhiro Furukawa, Satoshi Furune, Takashi Hirose, Keiko Hirai, Takahiro Suzuki, Emiko Hida, Hiroyuki Shibata, Hiroki Kawashima","doi":"10.17235/reed.2024.10339/2024","DOIUrl":"10.17235/reed.2024.10339/2024","url":null,"abstract":"<p><p>Ectopic pancreas (EP) is defined as pancreatic tissue that lacks anatomical or vascular connections to the normal pancreas. EP is generally asymptomatic and is detected incidentally during endoscopy. However, due to pseudocyst formation, inflammation, or malignant transformation, it may cause non-specific gastrointestinal symptoms, such as abdominal pain, abdominal discomfort, nausea, vomiting, and bleeding. Pseudocyst formation in EP may result from the retention of exocrine secretions in the absence of connections between the glandular epithelium and gastric lumen. We herein report a case of EP with a pseudocyst associated with epigastric pain. EP with a pseudocyst, although rare, needs to be considered in a differential diagnosis of cystic lesions of the stomach.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"158-160"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brais Fernández Suárez, Lucía Seoane Blanco, María Gómez Rivas, Andrea García Gómez, Lorena González Otero, Alba Roibás Veiga, Julieta Fernández Molina
{"title":"Primary follicular lymphoma of the duodenum as an incidental finding on upper gastrointestinal endoscopy.","authors":"Brais Fernández Suárez, Lucía Seoane Blanco, María Gómez Rivas, Andrea García Gómez, Lorena González Otero, Alba Roibás Veiga, Julieta Fernández Molina","doi":"10.17235/reed.2024.10255/2023","DOIUrl":"10.17235/reed.2024.10255/2023","url":null,"abstract":"<p><p>Primary follicular lymphoma of the duodenum (FLD) is a rare variant of follicular lymphoma (FL), which represents only 1-4% of gastrointestinal non-hodgkin lymphomas (NHL). It usually appears in the second portion of the duodenum as micronodular lesions and the diagnosis is often incidental. Unlike other NHLs, the prognosis is excellent and the treatment ranges from \"watch and wait\" to rituximab-based immunochemotherapy regimens, depending on the symptoms and the presence of systemic involvement.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"156-157"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Malignant melanoma with liver, stomach, and duodenal metastasis.","authors":"Yue Tian, Yong-Qin Ao, Yu-Ling Xiong, Chun-Xia Huang, Xin Jin, Li-Shuang Liu","doi":"10.17235/reed.2024.10851/2024","DOIUrl":"10.17235/reed.2024.10851/2024","url":null,"abstract":"<p><p>Malignant melanoma (MM) is a common and highly invasive malignant tumor in clinical practice that is prone to occur in the skin and mucosa and prone to early metastasis. The common sites of metastasis are the liver, lungs, brain, etc. Metastatic gastrointestinal mucosa is relatively rare. Once metastasis occurs, the prognosis of patients is significantly worse. This article reports a case diagnosed as MM with liver, stomach, and duodenal metastasis by ultrasound-guided endoscopic puncture at Fengdu People's Hospital in Chongqing, with gastrointestinal discomfort as the initial symptom and a history of melanoma. Therefore, when a patient has a history of melanoma surgery and presents with digestive symptoms, it is necessary to consider the disease. Regular endoscopic screening should be performed, and early surgical treatment and postoperative chemotherapy combined with targeted therapy may improve patient prognosis and prolong patient survival.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"172-173"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142506987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helena González-Sánchez, Andrés Castaño-García, Miriam Celada-Sendino, Pablo Flórez-Díez, Marta García-Calonge, Manuel Rodríguez, Valentina Chiminazzo, María Varela Calvo
{"title":"Demographic and survival characteristics of untreated hepatocellular carcinoma patients: insights into the natural history and prognostic determinants.","authors":"Helena González-Sánchez, Andrés Castaño-García, Miriam Celada-Sendino, Pablo Flórez-Díez, Marta García-Calonge, Manuel Rodríguez, Valentina Chiminazzo, María Varela Calvo","doi":"10.17235/reed.2025.11029/2024","DOIUrl":"https://doi.org/10.17235/reed.2025.11029/2024","url":null,"abstract":"<p><strong>Background: </strong>Hepatocellular carcinoma (HCC) patients with advanced symptoms or liver failure are often ineligible for transplantation, leading only to symptom control. Additionally, various factors lead to other HCC stage patients remaining in natural history.</p><p><strong>Objective: </strong>To describe the demographic of untreated HCC patients and to analyze survival-influencing factors.</p><p><strong>Methods: </strong>single-center retrospective observational study examining HCC patients diagnosed from 2015 to 2021 who received symptom control as their primary treatment. Baseline characteristics and survival data were collected and analyzed.</p><p><strong>Results: </strong>Of 685 HCC patients, 26% (n=181) remained in natural history, median age 71 years, 82% male patients, 93% with cirrhosis, 53% with previous decompensation. At a mean follow-up of 9.98 months, the mortality rate was 84%. While 49.8% of patients were BCLC-D stage, other reasons for remaining in natural history included frailty (25.4%) comorbidities (16%), and patient's treatment refusal (8%). Independent survival factors were BCLC stage, previous decompensation and diagnosis within the screening program, with 37% of untreated patients detected through surveillance.</p><p><strong>Conclusions: </strong>Liver function, BCLC stage and functional status influence survival in natural HCC history. A significant 37% diagnosed through screening indicates inclusion criteria refinement necessity to avoid overdiagnosis and optimize resources.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uncommon biliary strictures: diagnostic insights into biliary candidiasis.","authors":"Akihiro Maruyama, Takahiro Yamada, Makoto Kobayashi","doi":"10.17235/reed.2025.11113/2025","DOIUrl":"https://doi.org/10.17235/reed.2025.11113/2025","url":null,"abstract":"<p><p>We present a case of biliary candidiasis incidentally identified in a 71-year-old male who has the medical history of laparoscopic cholecystectomy performed 4 years ago. Laboratory examination revealed elevated biliary and liver enzyme levels. Abdominal contrast-enhanced computed tomography and endoscopic ultrasonography (EUS) revealed thickening of the common bile duct wall.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Colon ulcers and HIV: an image to remember.","authors":"Raquel Gómez Perosanz, Marta Quiñones Calvo","doi":"10.17235/reed.2025.11078/2025","DOIUrl":"https://doi.org/10.17235/reed.2025.11078/2025","url":null,"abstract":"<p><p>A 37-year-old HIV-positive male with a history of cutaneous Kaposi's sarcoma (KS) presented with chronic bloody diarrhea, abdominal pain, and weight loss despite an undetectable viral load and a CD4 count of 200 cells/mm³. Colonoscopy and gastroscopy revealed ulcers with erythematous-violaceous borders, and biopsies confirmed intestinal KS through HHV-8 positivity. Treated with paclitaxel, the patient showed significant clinical and endoscopic improvement. Visceral KS, though rare at higher CD4 counts, should be suspected in compatible cases. It often presents as diarrhea and abdominal pain, with or without skin lesions. Diagnosis requires HHV-8-positive biopsies, and treatment includes antiretroviral therapy and chemotherapy, such as paclitaxel or liposomal doxorubicin.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The future of artificial intelligence in Healthcare: smaller, more specialized language models.","authors":"Manuel Nevado Santos, Paula Nevado Álvarez","doi":"10.17235/reed.2025.11141/2025","DOIUrl":"https://doi.org/10.17235/reed.2025.11141/2025","url":null,"abstract":"<p><p>This letter discusses the shift from large proprietary AI models to smaller, specialized language models in healthcare. With advancements in fine-tuning techniques, such models can be adapted using affordable resources, ensuring data security and empowering smaller institutions. The letter emphasizes the importance of guiding AI development to complement human medical expertise.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}