{"title":"Pancreatic squamous cell carcinoma metastasizing along the puncture site 7 days after laparoscopic surgery.","authors":"Ziyuan Liu, Zhiqun Mao","doi":"10.17235/reed.2024.10907/2024","DOIUrl":"10.17235/reed.2024.10907/2024","url":null,"abstract":"<p><p>A 64-year-old man was admitted to the hospital due to \"recurrent abdominal pain for 8 months\" and had a history of multiple episodes of pancreatitis. CT scan showed an enlarged pancreas with no normal pancreatic tissue . Contrast enhancement scan in the arterial phase displayed moderate enhancement in the solid portion, while the cystic necrosis area showed no enhancement. It was suspected to be pancreatic cancer, and laparoscopic exploration of the pancreas followed by partial pancreatectomy was performed. Finally, it was confirmed as pancreatic squamous cell carcinoma by immunohistochemistry (P63 (+), CK5/6 (+)). Seven days after the operation, F18-FDG PET/CT showed multiple soft tissue density masses in the upper abdominal wall along the laparoscopic trajectory with increased uptake.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eri Nishikawa, Tetsuya Yoshizaki, Takashi Toyonaga, Yuzo Kodma
{"title":"Refractory gastrointestinal bleeding caused by splenic artery pseudoaneurysm rupture.","authors":"Eri Nishikawa, Tetsuya Yoshizaki, Takashi Toyonaga, Yuzo Kodma","doi":"10.17235/reed.2024.10854/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10854/2024","url":null,"abstract":"<p><p>A 64-year-old man was admitted for hematemesis. Esophagogastroduodenoscopy revealed a gastric ulcer with a visible vessel on the posterior wall of the gastric body. After admission, the patient developed multiple episodes of massive hematemesis. During emergent esophagogastroduodenoscopy, he developed hemodynamic instability due to spurting bleeding. On day 18 of hospitalization, hemostasis was achieved using hemostatic forceps; however, contrast-enhanced computed tomography performed on the same day revealed a small splenic artery pseudoaneurysm (SAP) that had not been previously detected. To prevent fatal re-bleeding, interventional radiology was performed, and coil embolization was applied proximal to the pseudoaneurysm. The patient recovered without further hematemesis. One month later, exposed coils were observed from the healing ulcer, and celiac trunk angiography confirmed splenic artery thrombosis. Despite multiple attempts at endoscopic intervention, the patient developed recurrent hematemesis, suggesting that the gastric ulcer had eroded into the splenic artery, forming the SAP and causing significant hemorrhage. Although SAPs secondary to gastric ulcers are extremely rare, early recognition is critical because they carry a high risk of rupture and mortality. Endoscopic procedure alone may be insufficient, and an endovascular approach is a standard treatment to prevent life-threatening re-bleeding.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Pablo-Martín, Laura Corvo-Félix, Marta Rodríguez González, Andrea Beatriz Jiménez Pérez, Luis Figuero-Pérez, María Luisa Pérez García, Emilio Fonseca-Sánchez
{"title":"Finding of celiac disease during the study of Kimura disease in a Caucasian male.","authors":"Elena Pablo-Martín, Laura Corvo-Félix, Marta Rodríguez González, Andrea Beatriz Jiménez Pérez, Luis Figuero-Pérez, María Luisa Pérez García, Emilio Fonseca-Sánchez","doi":"10.17235/reed.2024.10853/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10853/2024","url":null,"abstract":"<p><p>We present the case of a 27-year-old man, with no previous diseases, who was referred to the Department of Otorhinolaryngology in May 2023 for a 2-cm right submandibular lymphadenopathy of two month's evolution. He did not report fever or night sweats, and no oral or genital ulcers were observed. He presented eosinophilia in the analysis performed and a maculopapular exanthema on the left leg and malleolus areas, which was initially treated with topical antibiotic and corticosteroids. A soft tissue ultrasound revealed two right laterocervical lymphadenopathies at levels I and II. Given the suspicion of a primary hematological tumor, a PET-CT scan was conducted to complete the study, which revealed hypermetabolic laterocervical bilateral lymphadenopaties. In June 2023, a programmed cervicotomy was conducted, with complete excision of the right main lymphadenopathy in the Ib region, which showed a histological result of reactive lymphadenitis with intense eosinophilia, vascular proliferation, and fibrosis. These findings suggest Kimura disease as the first possibility. Due to sporadic episodes of choking that were not associated with specific food, persistent elevated IgE levels and eosinophilia in peripheral blood tests, and skin alterations, the study was completed with a gastroscopy to rule out the presence of eosinophilic esophagitis, which showed erosive duodenitis, with villous shortening and increased lymphoplasmacytic cellularity of the lamina propria, findings consistent with celiac disease, which was afterwards confirmed with the presence of positive anti-endomysial and transglutaminase antibodies, and the presence of HLA-DQ8 positive in homozygosis in the genetic study. The patient started systemic treatment with corticosteroids and gluten-free diet, which he continues to take at present.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ruptured pancreatic carcinosarcoma - A case of extended survival following surgical resection and chemotherapy.","authors":"Yekai Zhou, Xiaorong Chen, Jie Li, Fang Luo","doi":"10.17235/reed.2024.10856/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10856/2024","url":null,"abstract":"<p><p>We present a rare case of ruptured pancreatic carcinosarcoma in a 56-year-old male who underwent radical surgery and adjuvant chemotherapy. Despite the typical poor prognosis associated with this aggressive tumor, the patient achieved an overall survival of 20 months postoperatively. This case emphasizes the challenges in diagnosing and managing pancreatic carcinosarcoma and highlights the potential benefits of aggressive surgical and chemotherapeutic interventions in achieving extended survival.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Sánchez Moreno, Marta Fernández Carrasco, Sebastián Pinochet Almonacid, Matías Estévez Escobar
{"title":"An uncommon cause of dysphagia: esophagitis dissecans superficialis secondary to bullous pemphigoid after vaccination for SARS-CoV-2.","authors":"Sara Sánchez Moreno, Marta Fernández Carrasco, Sebastián Pinochet Almonacid, Matías Estévez Escobar","doi":"10.17235/reed.2024.10845/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10845/2024","url":null,"abstract":"<p><p>Esophagitis dissecans superficialis (EDS) is an uncommon condition that is infrequently associated with autoimmune dermatoses. We present the case of a 75-year-old patient who developed EDS secondary to bullous pemphigoid after vaccination against SARS-CoV-2, with typical endoscopic and histological findings.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolina Broco Fernández, Ana Belen Dominguez Carbajo, Santiago Vivas Alegre, Verónica Patiño Delgadillo, Laura Alcoba Vega, Francisco Jorquera Plaza
{"title":"Plummer-Vinson syndrome: is the immune system the missing piece?","authors":"Carolina Broco Fernández, Ana Belen Dominguez Carbajo, Santiago Vivas Alegre, Verónica Patiño Delgadillo, Laura Alcoba Vega, Francisco Jorquera Plaza","doi":"10.17235/reed.2024.10862/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10862/2024","url":null,"abstract":"<p><p>Plummer-Vinson syndrome (PVS) is a rare disorder characterized by a triad of iron-deficiency anemia, cervical dysphagia, and post-cricoid esophageal webs. The exact relationship between anemia and web formation remains unclear, with current hypotheses lacking strong evidence. Although treating anemia generally resolves dysphagia, some cases require endoscopic intervention. PVS is considered a precancerous condition due to its association with squamous cell carcinoma of the hypopharynx or upper esophagus. We present the case of a 53-year-old woman with psoriatic arthritis who exhibited iron-deficiency anemia unresponsive to oral iron and persistent dysphagia. Gastroscopy revealed esophageal narrowing, and she underwent successful balloon dilation following iron therapy. The patient is now asymptomatic. While the etiopathogenesis of PVS remains unknown, autoimmune conditions may play a role. Due to its potential link to neoplastic lesions, recognizing and managing PVS is critical. Further research is required to improve understanding and identify those at risk.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo Domínguez-Adame Lanuza, Cristina Rubio Castellanos, Manuel Rodríguez-Téllez
{"title":"Subtotal gastrectomy for giant gastric trichobezoar.","authors":"Eduardo Domínguez-Adame Lanuza, Cristina Rubio Castellanos, Manuel Rodríguez-Téllez","doi":"10.17235/reed.2024.10869/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10869/2024","url":null,"abstract":"<p><p>We present the case of a 22-year-old patient with a relevant previous history of trichophagia (Rapunzel Syndrome) in adolescence who presented Giant Gastric Trichobezoar that required subtotal gastrectomy for its resolution.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrés Castañeda, Marta Álvarez García, Cristina Serrano Del Castillo, Raquel Téllez Pérez, Ana Pilar Lanzarote Vargas, María José Romero Valle, Lonore Hurtado de Mendoza, Sergio Farrais Villalba
{"title":"Can flow cytometry be a key in the difficult diagnosis of coeliac disease?","authors":"Andrés Castañeda, Marta Álvarez García, Cristina Serrano Del Castillo, Raquel Téllez Pérez, Ana Pilar Lanzarote Vargas, María José Romero Valle, Lonore Hurtado de Mendoza, Sergio Farrais Villalba","doi":"10.17235/reed.2024.10833/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10833/2024","url":null,"abstract":"<p><p>We present the clinical case of a 39-year-old woman with a medical history of juvenile idiopathic arthritis and uveitis, evaluated for abdominal pain and distension, difficulty gaining weight, and diarrhea. Blood tests were requested, including antibodies which were negative and common genetic markers, showing positivity for HLA DQ 7.5. A gastroscopy with duodenal biopsies revealed findings consistent with stage 3b of the modified Marsh classification. Due to diagnostic uncertainty, an IEL study was performed, showing a characteristic CD pattern, leading to the initiation of a strict gluten-free diet (GFD). During follow-up, the patient showed partial improvement, with persistent digestive symptoms. A repeat endoscopic study revealed persistent atrophy, but refractory disease type 2 was ruled out. During a flare of rheumatologic disease, Tocilizumab was initiated by Rheumatology, resulting in improvement of duodenal atrophy.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolina Broco Fernández, Raisa Quiñones Castro, Laura Alcoba Vega, Verónica Patiño Delgadillo, Jesús Manuel Silva Fernández, Francisco Jorquera Plaza
{"title":"Challenges in metastatic hepatocellular carcinoma: beyond tumor stage in guiding treatment.","authors":"Carolina Broco Fernández, Raisa Quiñones Castro, Laura Alcoba Vega, Verónica Patiño Delgadillo, Jesús Manuel Silva Fernández, Francisco Jorquera Plaza","doi":"10.17235/reed.2024.10863/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10863/2024","url":null,"abstract":"<p><p>Extrahepatic metastases in hepatocellular carcinoma (HCC) often signify a poor prognosis. This case details the five-year survival of a patient with HCC and adrenal metastasis managed with an aggressive multimodal approach, including ablation, systemic therapy, and surgical resection. Despite therapeutic advances, metastatic HCC management remains a clinical challenge, underscoring the need for individualized treatment strategies beyond traditional staging systems. Further research is essential to determine the role of surgical resection and other treatment modalities in the metastatic setting.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intestinal follicular lymphoma, an atypical entity with typical endoscopic presentation.","authors":"Sandra Borrego Rivas, Alia Martín Izquierdo, Cristina Pisabarros Blanco, Jesús Espinel Díez","doi":"10.17235/reed.2024.10878/2024","DOIUrl":"https://doi.org/10.17235/reed.2024.10878/2024","url":null,"abstract":"<p><p>The most common extranodal localization of lymphomas is the small intestine, with large B-cell lymphoma and MALT lymphoma being the most typical types. Intestinal follicular lymphomas are an infrequent entity; however, due to improved endoscopic definition, diagnosis is more ando more common. We present the case of a 56-year-old woman diagnosed with follicular lymphoma, an entity that, although infrequent, has a typical endoscopic appearance. Recognition of the features described in this article may help to guide the diagnosis of this entity, which, on most occasions, has an indolent clinical course.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}