Revista espanola de cardiologia最新文献

{"title":"Caracterización de los patrones de flujo venoso hepático, portal y renal mediante ecografía Doppler según los grados de insuficiencia tricuspídea","authors":"Álvaro Rodríguez-Pérez ,&nbsp;Carlos Moliner-Abos ,&nbsp;David Viladés-Medel ,&nbsp;Juan Fernández-Martínez ,&nbsp;Josep Mayol-Domingo ,&nbsp;Adrián Ruíz-López ,&nbsp;Mario Salido ,&nbsp;Martín Descalzo ,&nbsp;Sandra Pujadas-Olano ,&nbsp;Irene Menduiña ,&nbsp;Lidia Bos-Real ,&nbsp;José A. Parada-Barcia ,&nbsp;Manuel Barreiro-Pérez ,&nbsp;Ilana Forado-Benatar ,&nbsp;Andrea Arenas-Loriente ,&nbsp;Rubén Leta-Petracca ,&nbsp;Dabit Arzamendi ,&nbsp;Chi Hion Pedro Li","doi":"10.1016/j.recesp.2025.08.011","DOIUrl":"10.1016/j.recesp.2025.08.011","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Hepatic, portal, and intrarenal venous flows are impaired in significant tricuspid regurgitation (TR), but the impact of massive and torrential TR remains unclear. This study assessed these venous flow patterns across the 5-grade TR classification and their potential as grading markers.</div></div><div><h3>Methods</h3><div>Patients with TR were prospectively included from 3 centers. Exclusion criteria were admission for heart failure, cirrhosis, and stage V renal disease. TR severity was classified using biplane vena contracta width and 2-dimensional effective regurgitant orifice area. Venous flow patterns (hepatic vein reverse systolic flow, portal pulsatility fraction, monophasic intrarenal flow, and reverse portal and intrarenal systolic flows) were analyzed for each TR grade.</div></div><div><h3>Results</h3><div>Of the 143 patients (52 grade III, 30 grade IV, 17 grade V TR), worsening TR was associated with progressively abnormal venous flow. Hepatic vein reverse flow had high sensitivity (96%) but lower specificity (73%) for grade III TR and was less useful for grades IV-V. Monophasic intrarenal flow had high specificity (97%) for grade III TR. Portal pulsatility fraction worsened with severity, with cutoffs of ≥ 40% for grade III, ≥ 80% for grade IV, and<!--> <!-->&gt; 100% for grade V. Reverse portal and intrarenal systolic flows were highly specific for grade V (94% and 97%, respectively).</div></div><div><h3>Conclusions</h3><div>Increasing TR severity correlates with abnormal hepatic, portal, and intrarenal venous flow patterns, which can be assessed through routine echocardiography.</div><div><em>Full English text available from</em>: <span><span>www.revespcardiol.org/en</span><svg><path></path></svg></span></div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 226-236"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacto a largo plazo de una estrategia intensiva basada en la telemedicina para el control lipídico","authors":"César Jiménez-Méndez ,&nbsp;Rafael Vázquez-García ,&nbsp;William Delgado,&nbsp;Daniel Bartolome,&nbsp;Etel Silva","doi":"10.1016/j.recesp.2025.05.003","DOIUrl":"10.1016/j.recesp.2025.05.003","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 273-275"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dinámica del recuento plaquetario intrahospitalario en pacientes con síndrome coronario agudo","authors":"Andrea Zito ,&nbsp;Antonio Landi ,&nbsp;Andrea Milzi ,&nbsp;Enrico Frigoli ,&nbsp;Sergio Leonardi ,&nbsp;Pascal Vranckx ,&nbsp;Arnoud W.J. Vant’Hof ,&nbsp;José M. de la Torre Hernández ,&nbsp;Gianluca Campo ,&nbsp;Ferdinando Varbella ,&nbsp;Paolo Calabrò ,&nbsp;Giuseppe Andò ,&nbsp;Giacomo Boccuzzi ,&nbsp;Filippo Russo ,&nbsp;Marco Valgimigli","doi":"10.1016/j.recesp.2025.09.001","DOIUrl":"10.1016/j.recesp.2025.09.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The prognostic role of platelet count dynamics in patients hospitalized with acute coronary syndromes (ACS) remains unclear. This study investigated the implications of platelet counts and their changes in ACS patients, using MATRIX trial data.</div></div><div><h3>Methods</h3><div>In-hospital relative changes in platelet count were analyzed continuously and were categorized into groups. Associations with 1-year risks of mortality and major or clinically relevant nonmajor bleeding were modelled using Cox regression.</div></div><div><h3>Results</h3><div>Among 7722 ACS patients, a platelet count drop &gt;<!--> <!-->10% occurred in 47.5% of the patients and a platelet count increase &gt;<!--> <!-->10% in 6.4%. Platelet count changes showed a U-shaped association with mortality and an L-shaped association with bleeding. Compared with the reference group (from 10% drop to 10% increase; rates: mortality 2.6%, bleeding 6.2%), platelet count drops were associated with an incremental mortality risk of approximately 30% (30%-50% drop: 9.5%; HR, 2.86; 95%CI, 1.93-4.23]; &gt;<!--> <!-->50% drop: 21.4% HR, 3.86; 95%CI, 2.21-6.74) and a bleeding risk of approximately 10% (10%-30% drop: 8.2%, HR, 1.34; 95%CI, 1.11-1.61; 30%-50% drop: 13.8%, HR, 2.01; 95%CI, 1.48-2.72; &gt;<!--> <!-->50% drop: 32.1%; HR, 4.59; 95%CI, 3.01-6.99). Platelet count increases were associated with an incremental mortality risk of approximately 10% (10%-30% increase: 5.8%; HR, 1.87; 95%CI, 1.18-2.98; 30%-50% increase: 8.5%; HR, 2.61; 95%CI, 1.05-6.44; &gt;<!--> <!-->50% increase: 9.7%; HR, 3.51; 95%CI, 1.10-11.22) but not with bleeding.</div></div><div><h3>Conclusion</h3><div>In ACS patients, platelet count drops were associated with incremental risks of mortality and bleeding, whereas platelet count increases were associated with an incremental risk of mortality but not bleeding.</div><div><em>Full English text available from</em>: <span><span>www.revespcardiol.org/en</span><svg><path></path></svg></span></div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 257-269"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uso del enfoque win ratio para evaluar los resultados del ensayo clínico DapaTAVI","authors":"Xavier Rossello ,&nbsp;Rafael Gonzalez-Manzanares ,&nbsp;Ignacio Amat-Santos ,&nbsp;Vicente Peral Disdier ,&nbsp;Luis Nieto Roca ,&nbsp;Diego López Otero ,&nbsp;Luis Nombela Franco ,&nbsp;Livia Gheorge ,&nbsp;Jorge Sanz-Sánchez ,&nbsp;Javier Gómez Herrero ,&nbsp;Rocío González Ferreiro ,&nbsp;Antonio Jesús Muñoz García ,&nbsp;Victoria Vilalta ,&nbsp;Soledad Ojeda ,&nbsp;Gabriela Veiga Fernández ,&nbsp;Juan Gabriel Córdoba Soriano ,&nbsp;Ander Regueiro ,&nbsp;Miriam Sandín Rollán ,&nbsp;Xacobe Flores Ríos ,&nbsp;Aitor Uribarri ,&nbsp;Sergio Raposeiras-Roubín","doi":"10.1016/j.recesp.2025.08.006","DOIUrl":"10.1016/j.recesp.2025.08.006","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The win ratio (WR) approach is used to assess composite endpoints in a hierarchical fashion. This novel method offers an excellent opportunity to assess the robustness of the findings yielded by landmark trials, such as the DapaTAVI trial.</div></div><div><h3>Methods</h3><div>We applied the WR method to evaluate the treatment effect of dapagliflozin in hierarchically ordered clinical outcomes. Several combinations of outcomes were tested, including time-to-event, binary, and continuous endpoints.</div></div><div><h3>Results</h3><div>The WR of the original primary endpoint was 1.36 (95%CI, 1.03-1.78; <em>P</em> <!-->=<!--> <!-->.028), comparable to the reciprocal of the original hazard ratio (1/HR, 1.38; 95%CI, 1.06-1.81). The win difference was 4.84% (95%CI, 0.55-9.12), confirming consistent findings in terms of absolute effect. Alternative combinations of the primary outcome with different prioritization of its components yielded similar treatment effects and statistical significance. Ignoring a time-to-event approach and including recurrent events did not substantially affect treatment efficacy and its statistical significance. In contrast, the inclusion of the total length of stay for heart failure hospitalizations in the hierarchy shifted the point estimate toward the null. Including New York Heart Association functional class improved the precision of the estimate (WR<!--> <!-->=<!--> <!-->1.31; 95%CI, 1.09-1.56; <em>P</em> <!-->=<!--> <!-->.003). Conversely, including quality of life through Kansas City Cardiomyopathy Questionnaire comparisons shifted the overall estimate toward the null (WR<!--> <!-->=<!--> <!-->1.10; 95%CI, 0.94-1.30; <em>P</em> <!-->=<!--> <!-->.236).</div></div><div><h3>Conclusions</h3><div>The WR approach is a solid method to assess treatment efficacy. We observed consistent findings using this approach in the DapaTAVI trial.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 215-225"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflexiones sobre la actualización ESC 2025 sobre el tratamiento de las dislipemias","authors":"Grupo de Trabajo de la SEC sobre la actualización ESC 2025 sobre el tratamiento de las dislipemias y Comité de Guías de la SEC","doi":"10.1016/j.recesp.2025.11.022","DOIUrl":"10.1016/j.recesp.2025.11.022","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 199-203"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Constantes vitales","authors":"Fernando A. Navarro","doi":"10.1016/j.recesp.2025.09.007","DOIUrl":"10.1016/j.recesp.2025.09.007","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Page 193"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carga acumulativa de la frecuencia cardiaca en reposo y riesgo cardiovascular en pacientes con insuficiencia cardiaca en ritmo sinusal","authors":"Jun Hao ,&nbsp;Jingyang Wang ,&nbsp;Rui Shi ,&nbsp;Qi Wang ,&nbsp;Xiaohua Cheng ,&nbsp;Jiayu Feng ,&nbsp;Yanmin Yang ,&nbsp;Yuxiao Hu ,&nbsp;Tao Chen ,&nbsp;Kangyu Chen","doi":"10.1016/j.recesp.2025.07.012","DOIUrl":"10.1016/j.recesp.2025.07.012","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Resting heart rate is a readily available vital sign with important prognostic significance. However, traditional measures overlook both the magnitude and duration of elevated heart rate over time. This study assessed the association between cumulative resting heart rate load and adverse outcomes in patients with chronic heart failure (HF) in sinus rhythm.</div></div><div><h3>Methods</h3><div>Data from 5 randomized controlled trials (BEST, GUIDE-IT, HF-ACTION, RELAX, and TOPCAT) were analyzed. Cumulative heart rate load was calculated as the area under the curve (AUC) for heart rate ≥70 beats per minute (bpm), relative to the total AUC prior to outcomes. The primary outcome was major adverse cardiac events (MACE), defined as the composite of cardiovascular death and hospitalization for HF. Cox proportional hazards regression models were used to examine associations with outcomes.</div></div><div><h3>Results</h3><div>A total of 5428 patients were included. Higher cumulative resting heart rate load was significantly associated with increased risk of MACE (hazard ratio [HR], 1.31; 95% CI, 1.24-1.38), cardiovascular death (HR, 1.17; 95% CI, 1.08-1.27), hospitalization for HF (HR, 1.34; 95% CI, 1.26-1.43), all-cause death (HR, 1.20; 95% CI, 1.12-1.29), and any hospitalization (HR, 1.20; 95% CI, 1.15-1.25). Cumulative resting heart rate load demonstrated superior predictive value for all outcomes compared with baseline heart rate, mean heart rate, heart rate standard deviation, and heart rate time in the target range with improvements in C-statistics, net reclassification improvement, and integrated discrimination improvement when added to base models.</div></div><div><h3>Conclusions</h3><div>Cumulative resting heart rate load provides stronger prognostic value for adverse outcomes in chronic HF. Incorporating this parameter into clinical practice may improve risk stratification and help identify high-risk patients who could benefit from intensive monitoring or therapeutic interventions.</div><div><em>Full English text available from</em>: <span><span>www.revespcardiol.org/en</span><svg><path></path></svg></span></div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 204-214"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arco aórtico en sacacorchos. Síndrome de PHACES","authors":"María Catalina Sánchez Cornelio ,&nbsp;Francisco Castillo-Castellón ,&nbsp;Leanny Alcántara Alcántara","doi":"10.1016/j.recesp.2025.09.002","DOIUrl":"10.1016/j.recesp.2025.09.002","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 189-190"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implante de stent para la estenosis recurrente tras la reparación del arco aórtico en niños pequeños: resultados a corto y medio plazo sin reintervenciones","authors":"Katarzyna Gendera ,&nbsp;Stanimir Georgiev ,&nbsp;Andreas Eicken ,&nbsp;Andrea Amici ,&nbsp;Alfred Hager ,&nbsp;Maria von Stumm ,&nbsp;Daniel Dilber ,&nbsp;Peter Ewert ,&nbsp;Pinar Bambul Heck","doi":"10.1016/j.recesp.2025.07.002","DOIUrl":"10.1016/j.recesp.2025.07.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Stent implantation has become the gold standard for the treatment of native coarctation of the aorta (CoA) and recurrent CoA in adolescents and adults. In smaller children, however, stent implantation remains technically challenging due to anatomical constraints and growth considerations. Furthermore, data on the optimal treatment strategy in this age group are still limited. This study retrospectively analyzed clinical outcomes in young children treated with <em>stent</em> implantation for recurrent aortic arch stenosis.</div></div><div><h3>Methods</h3><div>A total of 101 patients (63 male; 62%) with a body weight of less than 15<!--> <!-->kg were treated with endovascular <em>stent</em> implantation for restenosis of the reconstructed aortic arch (n<!--> <!-->=<!--> <!-->94; 93%) or native CoA (n<!--> <!-->=<!--> <!-->7; 7%). The median age at the time of stent implantation was 4.8 months (IQR, 3.2-9.6 months) with a median body weight of 5.9<!--> <!-->kg (IQR, 4.7-8.4<!--> <!-->kg). The median follow-up period was 46.4 months (IQR, 11.0-76.6 months).</div></div><div><h3>Results</h3><div>All procedures were successful, and no serious complications occurred. The peak-to-peak gradient decreased significantly from a median of 32.5<!--> <!-->mmHg (IQR, 17.3-46.0<!--> <!-->mmHg) to 0.0<!--> <!-->mmHg (IQR, 0.0-2.5<!--> <!-->mmHg; <em>P</em> <!-->&lt;<!--> <!-->.005). The diameter of the narrow segment increased from a median of 3.0<!--> <!-->mm (IQR, 2.0-4.0<!--> <!-->mm) to 6.9<!--> <!-->mm (IQR, 6.0-8.0<!--> <!-->mm; <em>P</em> <!-->&lt;<!--> <!-->.005). During follow-up, none of the patients required reoperation</div></div><div><h3>Conclusions</h3><div>Stent implantation is a safe and feasible treatment option in patients with restenosis after complex aortic arch reconstruction or native CoA in whom surgical treatment would pose an elevated risk of complications. However, repeated dilatations and, ultimately, intentional stent fracture are required during follow-up.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 142-150"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unidades de cuidados intermedios cardiológicos: base racional, dotación e indicaciones de ingreso. Posicionamiento de la SEC-ACICAC","authors":"Ana Viana-Tejedor ,&nbsp;Pedro Martínez Losas ,&nbsp;Rut Andrea-Riba ,&nbsp;Miguel Corbí-Pascual ,&nbsp;Sandra Rosillo ,&nbsp;Joaquín J. Alonso ,&nbsp;Alessandro Sionís ,&nbsp;Pablo Pastor ,&nbsp;Pablo Jorge-Pérez ,&nbsp;Cosme García-García","doi":"10.1016/j.recesp.2025.08.012","DOIUrl":"10.1016/j.recesp.2025.08.012","url":null,"abstract":"<div><div>Intermediate cardiac care units (IMCU) provide a level of care between hospital wards and cardiac acute care units. They are designed for patients who require close monitoring or noncritical support, such as those with acute coronary syndromes, acute heart failure (HF), arrhythmias, monitoring after structural interventional cardiology or electrophysiology procedures, or postoperative care following cardiac surgery. IMCU help optimize resources and relieve pressure on cardiac acute care units, thereby improving specialized care. Two levels of IMCU are defined: level 1, which offers noninvasive monitoring and basic life support, and level 2, which incorporates invasive arterial pressure monitoring, noninvasive mechanical ventilation, and equipment for complex procedures. Their structure should be functional, with single-patient rooms, effective communication with other services, and dedicated areas for health care personnel. Care is led by cardiologists with specific training, supported by highly specialized nursing staff, and requires continuous medical coverage (24<!--> <!-->hours a day, 7 days a week) based on well-defined clinical protocols. This model aims to provide efficient, safe, and excellence-driven care. The Spanish Society of Cardiology (SEC) promotes its development through this position statement of the SEC Ischemic Heart Disease and Acute Cardiovascular Care Association (SEC-ACICAC), intended to guide the implementation of IMCU in Spain.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 165-172"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}