Revista espanola de cardiologia最新文献

{"title":"Bloqueo de la conducción interauricular como consecuencia del aislamiento antral ampliado de las venas pulmonares","authors":"Amaia Martínez León , David Testa Alonso , María Salgado , Minel Soroa , Daniel García-Iglesias , David Calvo","doi":"10.1016/j.recesp.2024.11.018","DOIUrl":"10.1016/j.recesp.2024.11.018","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 6","pages":"Pages 571-573"},"PeriodicalIF":5.9,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144134696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eficacia y seguridad de los inhibidores de SGLT2 en pacientes con insuficiencia cardiaca según la función renal: revisión sistemática y metanálisis","authors":"David Hong,&nbsp;Minseok Hong,&nbsp;Onyou Kim,&nbsp;Heayoung Shin,&nbsp;Minjung Bak,&nbsp;Darae Kim,&nbsp;Jihoon Kim,&nbsp;Ki Hong Choi,&nbsp;Eun Kyoung Kim,&nbsp;Joo Myung Lee,&nbsp;Jeong Hoon Yang,&nbsp;Sung-A. Chang,&nbsp;Sung-Ji Park,&nbsp;Sang-Chol Lee,&nbsp;Seung Woo Park,&nbsp;Jin-Oh Choi","doi":"10.1016/j.recesp.2025.02.011","DOIUrl":"10.1016/j.recesp.2025.02.011","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>This study aimed to evaluate the efficacy and safety of sodium-glucose cotransporter 2 (SGLT2) inhibitors throughout the spectrum of kidney function in patients with heart failure (HF).</div></div><div><h3>Methods</h3><div>This meta-analysis included randomized controlled trials comparing SGLT2 inhibitors with placebo in patients with HF stratified by renal function. Literature from inception to June 8, 2024 was searched. The primary outcome was a composite of cardiovascular death or HF events.</div></div><div><h3>Results</h3><div>Five trials were identified, comprising 21 204 patients (10 605 in the SGLT2 inhibitor group and 10 599 in the placebo group) who were randomized and followed up for a weighted median duration of 1.8 years. When patients were classified by estimated glomerular filtration rate (eGFR) of 60<!--> <!-->mL/min/1.73 m², SGLT2 inhibitors reduced the risk of the primary outcome irrespective of kidney function (RR, 0.81; 95%CI, 0.75-0.87; <em>P</em> <!-->&lt;<!--> <!-->.01 for eGFR &lt;<!--> <!-->60<!--> <!-->mL/min/1.73 m²; RR, 0.79; 95%CI, 0.72-0.87; <em>P</em> <!-->&lt;<!--> <!-->.01 for eGFR≥ 60<!--> <!-->mL/min/1.73 m²; test for subgroup differences <em>P</em> <!-->=<!--> <!-->.75). The beneficial impact of SGLT2 inhibitors was consistently observed when patients were further subclassified by eGFR values of 20-30, 30-45, 45-60, and &gt;<!--> <!-->60<!--> <!-->mL/min/1.73 m² (test for subgroup differences, <em>P<!--> </em>=<!--> <!-->.54). Early eGFR decline showed a differential impact with increased risk only in the placebo subgroup (RR, 1.30; 95%CI, 1.15-1.47; <em>P</em> <!-->&lt;<!--> <!-->.01), but not in the SGLT2 inhibitor subgroup (RR, 0.99; 95%CI, 0.86-1.13; <em>P</em> <!-->=<!--> <!-->.84) (test for subgroup differences, <em>P</em> <!-->&lt;<!--> <!-->.01).</div></div><div><h3>Conclusions</h3><div>SGLT2 inhibitor therapy is safe and effective throughout the spectrum of kidney function and regardless of the initial decline in kidney function in patients with chronic HF.</div><div>Registered at PROSPERO: CRD42024565218.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 9","pages":"Pages 789-799"},"PeriodicalIF":5.9,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144895209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eficacia de la reparación percutánea de borde a borde para la insuficiencia tricuspídea en pacientes portadores de dispositivos cardiacos implantables: resultados del registro TRI-SPA","authors":"Andrea Ruberti ,&nbsp;Pedro Cepas-Guillén ,&nbsp;Julio Echarte-Morales ,&nbsp;Dabit Arzamendi ,&nbsp;Vanessa Moñivas ,&nbsp;Fernando Carrasco-Chinchilla ,&nbsp;Manuel Pan ,&nbsp;Luis Nombela-Franco ,&nbsp;Isaac Pascual ,&nbsp;Claudio E. Guerreiro ,&nbsp;Tomás Benito-González ,&nbsp;Ruth Pérez ,&nbsp;Iván Gómez-Blázquez ,&nbsp;Ignacio J. Amat-Santos ,&nbsp;Eduardo Flores-Umanzor ,&nbsp;Ignacio Cruz-González ,&nbsp;Ángel Sánchez-Recalde ,&nbsp;Ana Belén Cid Álvarez ,&nbsp;Manuel Barreiro-Pérez ,&nbsp;Laura Sanchis ,&nbsp;Xavier Freixa","doi":"10.1016/j.recesp.2025.01.016","DOIUrl":"10.1016/j.recesp.2025.01.016","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>This study aimed to assess the effectiveness and clinical outcomes of tricuspid transcatheter edge-to-edge repair (T-TEER) in patients with cardiac implantable electronic devices (CIEDs).</div></div><div><h3>Methods</h3><div>This subanalysis of the Transcatheter Tricuspid Valve Repair in Spain (TRI-SPA) registry included patients with at least severe tricuspid regurgitation (TR) who were treated with T-TEER between June 2020 and May 2023 in Spain. Patients with CIEDs and no or mild tricuspid lead-leaflet interaction were compared with those without CIEDs. The primary composite endpoint was all-cause mortality, heart failure-related hospitalization, and tricuspid valve reintervention at 12 months.</div></div><div><h3>Results</h3><div>Among 310 patients (mean age 75.5<!--> <!-->±<!--> <!-->9.1 years, 70% female) with significant TR treated with T-TEER, 35 (11%) had CIEDs. Device implantation success was high in both groups (97.1% in the CIED group vs 96.4% in the non-CIED group, <em>P</em> <!-->=<!--> <!-->.81), with a similar rate of ≤<!--> <!-->2+ residual TR (84.9% in the CIED group vs 91.0% in the non-CIED group, <em>P</em> <!-->=<!--> <!-->.26). Patients with CIEDs experienced comparable rates of the primary composite endpoint to the non-CIED group (23.8% vs 19.1%, respectively, HR, 1.40; 95%CI, 0.60-3.31; <em>P</em> <!-->=<!--> <!-->.44), sustained successful TR reduction (≤<!--> <!-->2+ in 55.0% vs 73.8%, <em>P</em> <!-->=<!--> <!-->.07), and functional improvement (NYHA class I/II 81.8% vs 79.9%, <em>P</em> <!-->=<!--> <!-->.79).</div></div><div><h3>Conclusions</h3><div>In a real-world setting, T-TEER seems to be an effective therapeutic option for selected patients with more than moderate TR and CIEDs with no or mild lead-leaflet interaction, offering comparable cardiovascular outcomes and clinical improvement to those without leads. However, the presence of CIEDs may represent an independent risk factor for TR recurrence.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 10","pages":"Pages 863-875"},"PeriodicalIF":5.9,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Del estetoscopio a la inteligencia artificial: decodificando la enfermedad tricuspídea","authors":"Covadonga Fernández-Golfín ,&nbsp;Ana García-Martín","doi":"10.1016/j.recesp.2025.03.012","DOIUrl":"10.1016/j.recesp.2025.03.012","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 10","pages":"Pages 848-849"},"PeriodicalIF":5.9,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Desarrollo y puesta en marcha de un plan nacional de salud cardiovascular. Estrategia en salud cardiovascular (ESCAV) española","authors":"Héctor Bueno ,&nbsp;Germán Seara ,&nbsp;María Rosario Azcutia ,&nbsp;María Jesús Rodríguez-García ,&nbsp;Sonia Peláez ,&nbsp;Yolanda Agra ,&nbsp;Carla A. Dueñas ,&nbsp;Pedro Gullón ,&nbsp;Pilar Aparicio Azcárraga ,&nbsp;en representación del Comité Asesor Multidisciplinar de la Estrategia en Salud Cardiovascular del Sistema Nacional de Salud (ESCAV)","doi":"10.1016/j.recesp.2024.11.022","DOIUrl":"10.1016/j.recesp.2024.11.022","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Cardiovascular disease (CVD) remains the leading cause of death in most countries; however, few specific political actions have been implemented to improve cardiovascular health at both national and international levels. We aimed to describe the methodology used for the development and initial rollout of Spain's Cardiovascular Health Strategy of the National Health System (ESCAV, <em>Estrategia en Salud Cardiovascular del Sistema Nacional de Salud</em>).</div></div><div><h3>Methods</h3><div>A multidisciplinary team comprising diverse stakeholders developed a national strategy to reduce the burden of CVD in Spain. The team used qualitative methodologies to identify and select priorities and design strategic map models.</div></div><div><h3>Results</h3><div>The strategy was structured around a matrix with 6 cross-cutting themes (citizen empowerment; health promotion, prevention, and early CVD detection; comprehensive management of acute and chronic CVD; health care coordination; equity; and knowledge management) and 4 longitudinal lines (ischemic heart disease, heart failure, arrhythmias, and valve disease). The framework was further supported by 3 overarching axes: continuity of care, patient safety, and leveraging of information systems. A total of 27 critical points were selected, leading to the definition of 99 strategic objectives (32 general and 67 specific) and 136 actions through iterative reviews and prioritization. Strategic maps were developed for the overall strategy and for each action line, incorporating 61 indicators to facilitate and monitor the development of the strategy.</div></div><div><h3>Conclusions</h3><div>ESCAV represents one of the most ambitious initiatives aimed at transforming a nation's cardiovascular health. The methods and steps undertaken in this process could serve as a valuable reference for other countries seeking to establish similar initiatives. Furthermore, it may act as a catalyst to advance efforts toward establishing a European plan for cardiovascular health.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 7","pages":"Pages 628-636"},"PeriodicalIF":5.9,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"«Falso positivo» en CRM de estrés en un paciente con amiloidosis cardiaca","authors":"Marcos Ferrández-Escarabajal,&nbsp;Gina LaRocca","doi":"10.1016/j.recesp.2025.02.012","DOIUrl":"10.1016/j.recesp.2025.02.012","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 10","pages":"Page 929"},"PeriodicalIF":5.9,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Localización de la oclusión total crónica y resultados tras la intervención coronaria percutánea o el tratamiento médico: seguimiento a 10 años de un registro unicéntrico","authors":"Woochan Kwon ,&nbsp;Taek Kyu Park ,&nbsp;Ki Hong Choi ,&nbsp;Joo Myung Lee ,&nbsp;Jeong Hoon Yang ,&nbsp;Young Bin Song ,&nbsp;Joo-Yong Hahn ,&nbsp;Hyeon-Cheol Gwon ,&nbsp;Seung-Hyuk Choi","doi":"10.1016/j.recesp.2025.01.022","DOIUrl":"10.1016/j.recesp.2025.01.022","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The clinical benefits of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) remain controversial. This study aimed to investigate whether PCI for CTO located in the left anterior descending artery (LAD) could have beneficial effects on clinical outcomes.</div></div><div><h3>Methods</h3><div>Patients were retrospectively selected from a single-center CTO registry and followed up for approximately 10 years. The patients were grouped based on the presence of LAD CTO and whether the CTO was revascularized. Inverse probability weighting adjustment was also performed. The primary outcome was the composite of cardiac death or myocardial infarction at 10 years.</div></div><div><h3>Results</h3><div>Among 1323 patients with CTO, 1034 were male, and 417 had LAD CTO. PCI was attempted in 72.2% of participants in the LAD CTO group and in 49.9% of those in the non-LAD CTO group. In the non-LAD CTO group, PCI did not significantly affect the primary outcome (medical therapy vs PCI, 20.7% vs 13.4%, adjusted HR: 0.72, 95%CI, 0.47–1.10; <em>P</em> <!-->=<!--> <!-->.13). However, a significant difference in the incidence of the primary outcome between the treatment methods was observed in the LAD CTO group (30.8% vs 15.4%; adjusted HR: 0.44; 95%CI, 0.25-0.81; <em>P</em> <!-->=<!--> <!-->.007). A significant interaction was observed between LAD CTO and treatment method (<em>P</em> for interaction<!--> <!-->=<!--> <!-->.011).</div></div><div><h3>Conclusions</h3><div>The benefits of PCI compared with medical therapy for CTO might be more apparent when the CTO is located in the LAD.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 10","pages":"Pages 850-859"},"PeriodicalIF":5.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Muerte súbita en un niño con hipercolesterolemia familiar homocigota y cardiomiopatía no compactada. ¿Es solo una coincidencia?","authors":"Daiana Ibarretxe-Guerediaga ,&nbsp;Cristina Marimón ,&nbsp;Albert Feliu ,&nbsp;Cèlia Rodríguez-Borjabad ,&nbsp;Núria Plana ,&nbsp;Lluís Masana","doi":"10.1016/j.recesp.2025.01.020","DOIUrl":"10.1016/j.recesp.2025.01.020","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 10","pages":"Pages 922-924"},"PeriodicalIF":5.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecocardiografía avanzada y análisis de conglomerados para identificar fenogrupos de insuficiencia tricuspídea secundaria con diferente riesgo","authors":"Luigi P. Badano ,&nbsp;Marco Penso ,&nbsp;Michele Tomaselli ,&nbsp;Kyu Kim ,&nbsp;Alexandra Clement ,&nbsp;Noela Radu ,&nbsp;Geu-Ru Hong ,&nbsp;Diana R. Hădăreanu ,&nbsp;Alexandra Buta ,&nbsp;Caterina Delcea ,&nbsp;Samantha Fisicaro ,&nbsp;Gianfranco Parati ,&nbsp;Chi Young Shim ,&nbsp;Denisa Muraru","doi":"10.1016/j.recesp.2025.02.005","DOIUrl":"10.1016/j.recesp.2025.02.005","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Significant secondary tricuspid regurgitation (STR) is associated with poor prognosis, but its heterogeneity makes predicting patient outcomes challenging. Our objective was to identify STR prognostic phenogroups.</div></div><div><h3>Methods</h3><div>We analyzed 758 patients with moderate-to-severe STR: 558 (74<!--> <!-->±<!--> <!-->14 years, 55% women) in the derivation cohort and 200 (73<!--> <!-->±<!--> <!-->12 years, 60% women) in the external validation cohort. The primary endpoint was a composite of heart failure hospitalization and all-cause mortality.</div></div><div><h3>Results</h3><div>We identified 3 phenogroups. The low-risk phenogroup (2-year event-free survival 80%, 95%<span>C</span>I, 74%-87%) had moderate STR, preserved right ventricular (RV) size and function, and a moderately dilated but normally functioning right atrium. The intermediate-risk phenogroup (HR, 2.20; 95%CI, 1.44-3.37; <em>P</em> <!-->&lt;<!--> <!-->.001) included older patients with severe STR, and a mildly dilated but uncoupled RV. The high-risk phenogroup (HR, 4.67; 95%CI, 3.20-6.82; <em>P</em> <!-->&lt;<!--> <!-->.001) included younger patients with massive-to-torrential tricuspid regurgitation, as well as severely dilated and dysfunctional RV and right atrium. Multivariable analysis confirmed the clustering as independently associated with the composite endpoint (HR, 1.40; 95%CI, 1.13-1.70; <em>P</em> <!-->=<!--> <!-->.002). A supervised machine learning model, developed to assist clinicians in assigning patients to the 3 phenogroups, demonstrated excellent performance both in the derivation cohort (accuracy<!--> <!-->=<!--> <!-->0.91, precision<!--> <!-->=<!--> <!-->0.91, recall<!--> <!-->=<!--> <!-->0.91, and F1 score<!--> <!-->=<!--> <!-->0.91) and in the validation cohort (accuracy<!--> <!-->=<!--> <!-->0.80, precision<!--> <!-->=<!--> <!-->0.78, recall<!--> <!-->=<!--> <!-->0.78, and F1 score<!--> <!-->=<!--> <!-->0.77).</div></div><div><h3>Conclusions</h3><div>The unsupervised cluster analysis identified 3 risk phenogroups, which could assist clinicians in developing more personalized treatment and follow-up strategies for STR patients.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 10","pages":"Pages 838-847"},"PeriodicalIF":5.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diferencias de sexo en pacientes sometidos a recambio valvular aórtico: una historia de dos corazones","authors":"Giovanni Occhipinti ,&nbsp;Andrea Alberto Ruberti ,&nbsp;Jorge Alcocer ,&nbsp;Marc Giménez-Mila ,&nbsp;Bárbara Vidal ,&nbsp;Ander Regueiro","doi":"10.1016/j.recesp.2025.01.014","DOIUrl":"10.1016/j.recesp.2025.01.014","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 10","pages":"Pages 916-918"},"PeriodicalIF":5.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}