S Narang, J B Kitzmiller, R Galler, R I Rios, N Narang
{"title":"[Genetics of anapheline populations. III. Electrophoretic analysis of Anopheles aquasalis (Diptera: Culicidae) (author's transl)].","authors":"S Narang, J B Kitzmiller, R Galler, R I Rios, N Narang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Genetic variation at 26 loci in a natural population of Anopheles aquasalis has been studied by zymogram technique. Average proportion of polymorphic loci is 23% (criterion I) and 34% (criterion II). On the average 8.1% of the genome is in heterozygous condition in each individual. The degree of genetic variability varies from locus to locus. Some enzymes such as AO, alpha-GPDH, 3 loci of HK, 3 loci of LAP, 3 loci of MDH, GOT, 3 loci of ODH and one locus of EST (EST-4), are monomorphic. Of the rest, proportion of heterozygosity varies from the minimum of 0.041 at Xdh-2 to a maximum of 0.493 at Est-2. Similarly, except for the loci Est-2 and Est-3, proportion of heterozygote individuals is extremely low. A. aquasalis has a higher genetic identity with A. evansae (I = 0.625) than with A. argyritarsis (I = 0.543). There seems to be direct correlation between the genetic variability of a species and its capacity to explore diverse ecological nitches.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 4-5","pages":"303-9"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Kohn, G Cotta-Pereira, M L Lopez-Alvarez, W M Kattenbach
{"title":"Oxytalan fibers in the Schistosoma mansoni tegument.","authors":"A Kohn, G Cotta-Pereira, M L Lopez-Alvarez, W M Kattenbach","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to elucidate the nature of the fibrous network present in Schistosoma mansoni tegument, adult worms were studied by light and electron microscopy. It was suggested that this network is formed by bundles of tubular microfibrils 10--12 nm in diameter, similar to oxytalan microfibrils present in higher animals.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 4-5","pages":"335-8"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Electron microscopy of collagen resorption by fibroblasts in wound repair of the albino rat skin.","authors":"A Uzunian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The ultra-structural study of rat skin repair process at 7, 14 and 21 days has shown a greater collagenous resorption activity on the seventh days of the repair process.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 4-5","pages":"347-50"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolism of aromatic compounds by yeasts isolated from a polluted estuary in Rio de Janeiro, Brazil.","authors":"A S Pinto, M E Bomfim, A N Hagler, J Angluster","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 4-5","pages":"339-46"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11778114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Information on a wild rodent and marsupial collection from a \"cerrado\" region of Central Brazil (author's transl)].","authors":"D A Mello, L E Moojen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A list of wild rodents and marsupials from \"cerrado\" region captured in six conties of Goiás, Mato Grosso State and Federal District of Brasil, is presented. This list includes twenty-four rodent species and four marsupials species.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 4-5","pages":"287-91"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11338515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative immunogenicity of BCG substrains for mice.","authors":"L P Júnior, P P Gontijo Filho","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Immunogenicity of four substrains of BCG was studied in mice vaccinated by the intravenous route and evaluated through pulmonary density and through splenic, hepatic and pulmonary indexes (weight of the organ/weight of the animalx100). In addition, tuberculin sensitivity was determined by measuring the thickness of the inoculated leg. All four strains (BCG Brazil, BCG Prague, BCG Russia and BCG Glaxo) showed intermediary virulence (0.78 -- 0.85) between pathogenic mycobacteria, i.e., M. tuberculosis and non-pathogenic mycobacteria, such as M. fortuitum, without however revealing differences among themselves in regard to pulmonary density. Reinoculation of vaccinated animals by the intravenous route, contrary to the subcutaneous route, resulted in significant increase (P less than 0.05) in the organs, except for the spleen. The tuberculin hypersensitivity induced by the four strains was significant and it was possible to distinguish BCG Brazil from BCG Glaxo. The substrain BCG Brazil proved to be the most immunogenic, followed by BCG Prague, whereas BCG-Glaxo proved to be the weakest vaccine.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 4-5","pages":"311-6"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11600733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H de Franca Borges, M A da Silva Saragoça, C E Kater, A B Ribeiro, H Ajzen, O L Ramos
{"title":"[Effect of saralasin infusion on glomerular filtration rate and sodium excretion in hypertensive patients (author's transl)].","authors":"H de Franca Borges, M A da Silva Saragoça, C E Kater, A B Ribeiro, H Ajzen, O L Ramos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Saralasin (S) infusion, at a dose of 10 micrograms/kg/min IV, decreased Glomerular Filtration Rate (GFR) in 18 hypertensive patients. This effect was more pronounced in those patients with angiotensinogenic hypertension due to the somation of the effects of S upon renal vasculature and systemic arterial pressure. A decrease in urinary sodium excretion was also observed being more intense in those patients whose systemic pressure also decreased during S infusion. In group II (10 hypertensive patients) infusion of S in increasing doses (0.1, 0.5, 1.0, 5.0 and 10.0 micrograms/kg/min) a progressive decrease in GFR was observed only when the arterial pressure also decreased. However urinary sodium excretion decreased progressively as S doses increased. This effect was not related to S effect upon arterial pressure. This observation indicates that S, like angiotensin II, has a direct effect upon the renal tubules evoking an increase of sodium reabsorption.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 4-5","pages":"293-302"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of clofibrate on plasma lecithin: cholesterol acyltransferase (LCAT) activity in rats.","authors":"J R Cisternas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Effects of clofibrate on plasma lecithin: cholesterole acyltransferase (LCAT) activity, plasma lipid levels and hepatic cholesterol content were examined in rats with clofibrate treatment for a short period of time. The results show that the administration of the drug for three weeks produces substantial shifts in hepatic cholesterol fractions and induces changes in the plasma LCAT enzyme. It is suggested that clofibrate increases plasma LCAT activity by induction of the enzyme on the microsomal fraction of the hepatic cell and subsequent secretion by the liver. Presumably clofibrate treatment also produces an increase in the rate of hydrolysis of cholesteryl esters in the rat liver.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 4-5","pages":"317-24"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11735075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R D Pedro, L C Dias, V Amato Neto, S A De Carvalho
{"title":"Observations on the treatment of mansoni schistosomiasis with oxamniquine.","authors":"R D Pedro, L C Dias, V Amato Neto, S A De Carvalho","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"207-11"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11719442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Walker's 256 carcinosarcoma: metastatic dissemination in two cell lines (author's transl)].","authors":"M C De Mattos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Walker's 256 carcinosarcoma a transplantable tumor of the rate changes its behaviour as a consequence of various factors. In this paper we compare the evolution of 2 lines of the tumor: WM 16 (muscular) and Christ Hospital (ascitic) both inoculated intramuscularly. Animals receiving line WM 16 had a severe rapidly progressive evolution dying around day 14 after inoculation with diffuse metastases to lymph nodes (65% of animals), kidneys (53%), spleen (50%), lungs (46.5%), liver (45%), bone marrow (44.8%), in 56% of the animals there were circulating tumoral cells. Animals receiving Christ Hospital line survived up to 40 days, metastases were limited do lungs (48.7%) and lymph nodes (31.7%) and only in 2 of 45 animals circulating tumoral cells were observed.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"147-53"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11719436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}