{"title":"Some repair effectiveness coefficients as indicators of E. coli UV-resistance.","authors":"J V Pélico, R A Gomes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mathematical studies of E. coli survival curves to UV (254 nm) lead to the definition of a photoresistance parameter - the \"mean survival dose\" (MSD) - to compare radiation resistances of genetically related bacterial strains. Based on this MSD-parameter some repair coefficients were proposed as indicators of the relative effectiveness with which every repair system recovers radiation lesions in cells. The theoretical values calculated for the proposed coefficients are in agreement with those which were obtained from experimental data presented in the literature.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"111-6"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11598680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Laboratory investigation of hemoglobinopathies (author's transl)].","authors":"P C Naoum","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The importance of the haemoglobinopathies, mainly thalassaemia, as a public health problem has been emphasized. The establishment of methods for detection and diagnosis of haemoglobinopathies is the major step in laboratories dedicated to screening anemias. Tables for the diagnosis of alpha and beta thalassaemia are proposed, the methods to identify abnormal haemoglobins are discussed and a map with the relative mobilities of 115 abnormal haemoglobins by electrophoresis in alkaline buffer is shown.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"213-21"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11265025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R G Bevilacqua, N F Margarido, L A Soares, R Mansur, V Koch, E L Gonçalves
{"title":"[Effects of choledochal perfusion with biliary acid solutions on activity of the sphincter of Oddi (author's transl)].","authors":"R G Bevilacqua, N F Margarido, L A Soares, R Mansur, V Koch, E L Gonçalves","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The changes of sphincter of Oddi's resistance, induced by choledochal perfusion of conjugated (taurocolic) and non-conjugated (colic) biliary acid solutions, in anesthetized dogs, were studied. The perfusions were made at a constant flow and intracholedochal pressures were registered. The mean number of contractions per minute, the mean maximal pressures and the mean minimal pressures in each study periods were analysed. The choledochal perfusion with the biliary acids solutions induced a slight but significative increase in sphincteric resistance. After 15 minutes, the perfusion with colic acid solution induced maximal pressures significantly more elevated than the ones observed with taurocolic acid solution. The non-conjugated solution induced a pressure tracing significantly distinct from the tracing observed with the conjugated acid solution. No changes in resistance were observed with a 2% NaCl solution. This implies that the observed changes in resistance were not related to osmotic stimulation of the sphincter of Oddi.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"177-83"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11719440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D C Pessoa, E S Lago, L P De Freitas, N L Antunes, F M Bion, R B De Medeiros
{"title":"[Bean and rice mixtures of high protein value (author's transl)].","authors":"D C Pessoa, E S Lago, L P De Freitas, N L Antunes, F M Bion, R B De Medeiros","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The optimum content of different rice (Oryza sativa) and bean (Vigna unguiculata L.) combinations was studied in Albino rats. The mixture containing 3 g of rice proteins, corresponding to 41g of rice \"in natura\", and 7 g of bean protein, corresponding to 59 g of bean \"in natura\", presented the highest protein efficiency ratio and the feed efficiency ratio. Since the limiting amino acid of this mixture was methionine, new assays using varying levels of this amino acid as a supplement were carried out. The PER of normal rats as well as the \"plateau\" value of previously protein depleted rats were highest when 0.2% methionine was added to the mixture. The net protein utilization (NPU) confirmed these findings. The values attained after the addition of other amino acids were not higher than those attained by the mixture containing 7 g of bean protein and 3 g of rice protein supplemented with 0.2% methionine. The PER and the NPU values came close to those of milk.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"127-32"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11719650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Fetal macrosomy in alloxanized rats (author's transl)].","authors":"M D Guerra, V M Peters","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this work was to observe the starting of fetal macrosomy during the gestation of the diabetic rat and whether the sex of the fetuses has any influence on it. Lesions were produced in the B cells of the pancreas by the administration of alloxan on the 4th gestation day. The length and weight of the fetuses were not altered by this treatment before the 14th day of pregnancy, suggesting that fetal macrosomy should occur after this day.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"185-8"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11598684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I D Ricciardi, M C Ferreira, S S Otto, N Oliveira, A Sabrá, C F Fontes
{"title":"Thermophilic Campylobacter-associated diarrhoea in Rio de Janeiro.","authors":"I D Ricciardi, M C Ferreira, S S Otto, N Oliveira, A Sabrá, C F Fontes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thermophilic Campylobacter is reported as the agent associated with chronic and acute diarrhoea in Rio de Janeiro. Nine strains were isolated from 186 children with gastroenteritis. To our knowledge this is the first report of human Campylobacteriosis in Latin-America.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"189-91"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11719441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Histochemical and electrophoretical studies in normal and infected Biomphalaria glabrata. II. Acid and alkaline phosphatase.","authors":"M A Dardenne, T M Danni, N Narang, S Narang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Various organs of normal and infected Biomphalaria glabrata were analysed, electrophoretically and histochemically, with respect to the acid phosphatase and alkaline phosphatase activity. In general, digestive gland, ovotestis and stomach show an increase in acid phosphatase activity in infected snails, whereas kidney and albumen gland show less activity. Alkaline phosphatase does not show any significant different in activity between normal and infected snails. Electrophoretically digestive glands of snails, twenty days after infection, show an extra faint band, whereas seven days after infection, the snails do not show any such extra band. Histochemically also after twenty days, infected snails show more activity in the sporocyst region, but those infected for only seven days, do not show any increase in acid phosphatase activity.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"133-9"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11719651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Treatment of bleeding esophageal varices by embolization of the left gastric vein. (Preliminary note) (author's transl)].","authors":"W F Porto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author reports eleven cases of embolization of the left gastric vein in patients with esophageal varices due to schistosomotic hepatic fibrosis. The technique of the procedure is briefly described. The results have been favourable and no recurrence of bleeding was observed so far.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"193-5"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11528691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lack of evidence for hepatic control of renal sodium excretion in rats.","authors":"Y Okay, V W Velhote, M Marcondes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Three experimental protocols were used: a) normal and partially hepatectomized rats were expanded with isotonic saline; b) normal rats were expanded with isotonic saline; b) normal rats were infused with hypertonic saline (5%), either by the femoral or portal vein and c) hypertonic saline was sequentially and alternatively infused into normal rats via portal and femoral veins. All the experiments were made under anesthesia. Inulin clearance and absolute and fractional urinary sodium and potassium excretion were measured. Multiple analysis of variance was made to compare normal and partially hepatectomized rats, as well as portal and femoral infusions made either in the same or in different animals. In none of these experiments it was possible to demonstrate an effect of the liver in enhancing the natriuresis induced by saline infusions.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"155-64"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11719437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J L Ramos, E Coelho, M Z Salem, F A Vaz, E M Diniz, R Brock, H B Corradini, M Jamra
{"title":"[Progressive antithrombin activity in blood of pregnant women and neonates in the first four days of life (author's transl)].","authors":"J L Ramos, E Coelho, M Z Salem, F A Vaz, E M Diniz, R Brock, H B Corradini, M Jamra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Progressive antighrombin activity was assayed in 45 term infants in the first four days of life, in 20 cord blood specimens and in the blood of 20 pregnant women (at term). In the term infants a positive correlation was shown between progressive antithrombin and postnatal age. No correlation could be demonstrated with sex, ethnic group or type of delivery. Maternal antithrombin activity was shown to be moderately decreased, maternal values being closely related to cord blood values.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"12 2-3","pages":"169-75"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11719439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}