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Revista brasileira de pesquisas medicas e biologicas最新文献

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Pathological involvement of human gastrocnemius muscle in leptospirosis (a study in 63 patients). 钩端螺旋体病中人腓肠肌的病理累及(63例患者的研究)。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
J B Guedes e Silva, L M Paiva, J J Pereira da Silva, B A de Souza Netto
{"title":"Pathological involvement of human gastrocnemius muscle in leptospirosis (a study in 63 patients).","authors":"J B Guedes e Silva,&nbsp;L M Paiva,&nbsp;J J Pereira da Silva,&nbsp;B A de Souza Netto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors discuss the microscopic changes in gastrocnemius muscle in Leptospirosis in 63 patients. The hyaline necrosis frequently associated to a hemorrhagic infiltrate represented the most important feature in the lesional picture of the disease. Other findings were swelling, loss of cross striations, vacuolation and regenerative changes of muscle fibres. This last one was represented by multinucleated sarcoblasts and the presence of thin and strongly basophilic new-formed fibres. Interstitial hemorrhage was frequently seen and an inflammatory afflux was only rarely observed. This histological picture was considered as characteristic and highly significant for the diagnosis of Leptospirosis.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"9-13"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17223767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies of the persistence of infectivity of Trypanosoma cruzi. III. Effect of human sweat. 克氏锥虫传染性持久性的研究。3人体汗液的作用。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
V A Soares, P D Marsden
{"title":"Studies of the persistence of infectivity of Trypanosoma cruzi. III. Effect of human sweat.","authors":"V A Soares,&nbsp;P D Marsden","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Experiments designed to investigate the suggestion that human sweat has a trypanocidal effect did not support this hypothesis under the test conditions described. These studies are designed to investigate factors influencing the chance of infection of man when metacyclic trypanosomes in bug faeces are deposited on the human skin. As mentioned in the first paper in this series (Alvarenga & Marsden) we have epidemiological evidence that people can live for years in houses with infected bugs and not acquire the disease although skin contamination with infected faeces must occur frequently. Wood showed that metacyclic trypanosomes of T. cruzi lost their motility within 30 minutes after exposure to human sweat. He did not report infectivity experiments. Since such an effect would limit the chances of T. cruzi transmission under field conditions we decided to repeat Wood's experiments with observations on the infectivity of trypanosome suspensions.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"53-5"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17826876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the El Kholy technique for grouping beta-hemolytic streptococci. El Kholy技术对乙型溶血性链球菌分类的评价。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
A M Figueiredo, L C Benchetrit, A A Borges-Neto, C M Oliveira
{"title":"Evaluation of the El Kholy technique for grouping beta-hemolytic streptococci.","authors":"A M Figueiredo,&nbsp;L C Benchetrit,&nbsp;A A Borges-Neto,&nbsp;C M Oliveira","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One hundred and eleven strains of beta-hemolytic streptococci of human origin were grouped by the new nitrous acid procedure described by El Kholy et al. The results were comparable to the grouping obtained by the classical Lancefield hot-hydrochloric acid method. The El Kholy technique is simple and economic and is shown to be as sensitive and specific as the Lancefield procedure. We recommend the new method for routine use in the clinical laboratory and in studies on the prevalence of Streptococcus pyogenes in a developing country such as Brazil.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"21-4"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18426369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The developing human muscle: ultrastructural differences between myoblasts and fibroblasts. 发育中的人体肌肉:成肌细胞和成纤维细胞的超微结构差异。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
G Mingueitti, W G Mair
{"title":"The developing human muscle: ultrastructural differences between myoblasts and fibroblasts.","authors":"G Mingueitti,&nbsp;W G Mair","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Material from foetuses of nine weeks to nine months development was examined by electron microscopy to obtain some information about the various stages in the development of skeletal muscle and structures which are intimately related to it, such as blood vessels, nerves, neuromuscular spindles, fibroblasts and their product, i.e., collagen. Regarding the myoblasts and fibroblasts it was interesting to compare their ultrastructural features since there has been some difficulty in the identification of these two types of mononucleated cells by the authors which deal with light microscopy in the study of developing skeletal muscle. It was possible to note that between nine and eighteen weeks of development the muscle is different from mature skeletal muscle and is composed predominantly of two populations of muscle cells. These are the myoblasts which are mononucleated cells and the myotubes which are multinucleated muscle cells. After eighteen weeks of development there occur only muscle fibres similar to those of adult muscle. Fibroblasts also occur frequently in the developing muscle: they too are mononucleated cells. Fibroblasts and collagen fibrils are seen between the muscle cells and structures related to them as early as nine weeks of development. Bundles of collagen were also seen in the cytoplasm of fibroblasts.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18426367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dynamic evaluation of prolactin secretion in acromegaly (author's transl)]. 肢端肥大症患者催乳素分泌的动态评价[作者译]。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
A R Chacra, M Zampieri, A M Lengyel, J G Vieira
{"title":"[Dynamic evaluation of prolactin secretion in acromegaly (author's transl)].","authors":"A R Chacra,&nbsp;M Zampieri,&nbsp;A M Lengyel,&nbsp;J G Vieira","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The basal PRL levels and after estimulation with synthetic TRH were evaluated in 12 patients with active acromegaly, and in 12 normal individuals. None of the patients had galactorrhea and 5 of them had tumoral supra-sellar extension. Basal hyperprolactinemia was detected in 66% of the patients. After TRH stimulation, only 4 patients exhibited a percentual increment greater than 100% over the PRL basal value. PRL response to TRH was negative in 8 patients. The high PRL levels can be explained by the parallel production of GH and PRL by the tumoral cells, nevertheless a disturbance of the normal hypothalamic control cannot be excluded.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"57-64"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17826877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Histoenzymologic data on the epithelial cells of the gastric mucosa of marmosets (Callithrix jacchus & Callithrix penicillata)]. [绒猴(Callithrix jacchus & Callithrix penicillata)胃粘膜上皮细胞的组织酶学数据]。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
T Miraglia, C S Moura, L A Chezzi
{"title":"[Histoenzymologic data on the epithelial cells of the gastric mucosa of marmosets (Callithrix jacchus & Callithrix penicillata)].","authors":"T Miraglia,&nbsp;C S Moura,&nbsp;L A Chezzi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The gastric mucosa of marmosets is devoid of UDPG-GT; phosphorylases; G-6-PA; F-1,6-PA; alanyl aminopeptidase and leucine aminopeptidase. Only the acid phosphatase was seen with a stronger reactivity in the chief cells. The other enzymes (LDH; G-6-PDH; 6-PGDH; NADPH2-TR; cis-aconitase; ICDH; SDH; MDH; cytochrome oxidase; NADH2-TR; a-GPDH; b-OHBDH and nonspecific esterase) showed a stronger reactivity in the parietal cells.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"65-9"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17826879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of different doses of chlorhydrate of 1-isopropilamine-3-(1-naphtyl-oxy)-2-propranolol on glycogen of liver cells of pregnant rats and their fetuses. Histochemical and biochemical study. 不同剂量1-异丙拉胺-3-(1-萘基氧)-2-心得安水合物对妊娠大鼠及胎儿肝细胞糖原的影响。组织化学和生物化学研究。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
L Kulay, M J Simôes, M I Egami, M N Kulay, E R Paiva, A M Carvalho
{"title":"The effect of different doses of chlorhydrate of 1-isopropilamine-3-(1-naphtyl-oxy)-2-propranolol on glycogen of liver cells of pregnant rats and their fetuses. Histochemical and biochemical study.","authors":"L Kulay,&nbsp;M J Simôes,&nbsp;M I Egami,&nbsp;M N Kulay,&nbsp;E R Paiva,&nbsp;A M Carvalho","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18426368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haemoglobin J Rovigo 53 alpha (E-2) aspartic acid alanin. 血红蛋白J Rovigo 53 α (E-2)天冬氨酸丙氨酸。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
J T Araujo, D Plowman, R A Araujo, L F de Souza, H Lehmann
{"title":"Haemoglobin J Rovigo 53 alpha (E-2) aspartic acid alanin.","authors":"J T Araujo,&nbsp;D Plowman,&nbsp;R A Araujo,&nbsp;L F de Souza,&nbsp;H Lehmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The case under examination is an example of a family with Hb J Rovigo interacting with beta thalassemia. Such hemoglobin has the same mobility as J haemoglobin, and the analysis of amino acids showed it to be a variant of the alpha 53 (E2) Alanine-Aspartic chain. The percentage of haemoglobin ranged from around 22.7 to 30.5%.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"37-9"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18426370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rubella in Rio de Janeiro: a four year (1973--1976) sero-epidemiologic study in young women (author's transl)]. [里约热内卢风疹:一项为期四年(1973- 1976)的年轻女性血清流行病学研究[作者译]。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
J A Sturm
{"title":"[Rubella in Rio de Janeiro: a four year (1973--1976) sero-epidemiologic study in young women (author's transl)].","authors":"J A Sturm","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We did 2,707 hemagglutination inhibition reactions in 2,574 young women's sera (26.5 +/- 5 years old). The results show that 76% of the sera had antibodies. The number of serologic convertions was higher in 1974. This finding is in accordance with other evidences of a rubella epidemic in that year.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"47-52"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18426371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anticholinesterase activity of tranylcypromine and its isomers. 丙酰环丙氨酸及其异构体的抗胆碱酯酶活性。
Revista brasileira de pesquisas medicas e biologicas Pub Date : 1980-04-01
Z B Fortes, C C Reis, R Scivoletto
{"title":"Anticholinesterase activity of tranylcypromine and its isomers.","authors":"Z B Fortes,&nbsp;C C Reis,&nbsp;R Scivoletto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The anticholinesterase (antiChE) activity of ranylcypromine (TRCY) and its isomers was studied by employing dog plasma as a cholinesterase source. Changes in arterial blood pressure, elicited by a mixture of acetylcholine (Ach) and dog plasma with or without those drugs, as an indicator of their anti ChE activity were monitored. When TRCY or one of its isomers was present in concentrations higher than 125 microM in plasma containing Ach, the hypotensive effect of the latter was preserved. Such findings provide experimental evidence that TRCY and its isomers may exert antiChE activity.</p>","PeriodicalId":21265,"journal":{"name":"Revista brasileira de pesquisas medicas e biologicas","volume":"13 1-3","pages":"71-4"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18426372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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