Reumatismo最新文献_第10页

Cross-cultural adaptation, reliability, and validity of the Turkish version of the Exercise Therapy Burden Questionnaire for individuals with chronic diseases. 土耳其版慢性病患者运动疗法负担问卷的跨文化适应性、可靠性和有效性。

IF 1.2

Reumatismo Pub Date : 2024-06-24 DOI: 10.4081/reumatismo.2024.1684

F Sari, S Sari

{"title":"Cross-cultural adaptation, reliability, and validity of the Turkish version of the Exercise Therapy Burden Questionnaire for individuals with chronic diseases.","authors":"F Sari, S Sari","doi":"10.4081/reumatismo.2024.1684","DOIUrl":"https://doi.org/10.4081/reumatismo.2024.1684","url":null,"abstract":"Objective: Chronic diseases, which caused 36 million deaths in 2008, are the most common cause of death worldwide. Exercise is one of the non-pharmacological treatment methods. Although exercise benefits are well known, more than half of the population does not exercise due to the burden of exercise. The objectives of the current study were to evaluate the Turkish version of the Exercise Therapy Burden Questionnaire (ETBQ-T) and to investigate its reliability and validity.Methods: A total of 100 participants (female: 69, male: 31) who were diagnosed with at least one chronic disease participated in the translation validity and reliability analysis of the study. Cross-cultural adaptation of the ETBQ-T was performed according to Beaton's guidelines. The ETBQ-T, the European Quality of Life 5 Dimensions (EQ-5D), pain, satisfaction, and self-efficacy were applied for convergent validity. The ETBQ-T was retested to examine its reliability after 7 days.Results: The internal consistency and reliability were excellent (intraclass correlation coefficient=0.959; Cronbach's α=0.919). The standard error of measurement was reported as 5.35. The minimum detectable difference was also demonstrated at 1.35. The ETBQ-T had a good correlation with pain (r=0.545, p<0.001), satisfaction (r=-501, p<0.001), and self-efficacy (r=-0.579, p<0.001). However, the correlation of the ETBQ-T with EQ-5D (r=0.340, p=0.001) was weak. A factor was extracted, accounting for 58.289% of the total variation. There were no floor or ceiling effects.Conclusions: The ETBQ-T is a reliable and valid tool to evaluate the exercise burden in the Turkish population with chronic disease.","PeriodicalId":21222,"journal":{"name":"Reumatismo","volume":"76 2","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disease activity assessment for juvenile idiopathic arthritis in transitional care. 在过渡性护理中对幼年特发性关节炎进行疾病活动评估。

IF 1.2

Reumatismo Pub Date : 2024-06-24 DOI: 10.4081/reumatismo.2024.1638

F La Torre, C Coppola, M G Anelli, F Cacciapaglia, G Lopalco, F Cardinale, F Iannone

{"title":"Disease activity assessment for juvenile idiopathic arthritis in transitional care.","authors":"F La Torre, C Coppola, M G Anelli, F Cacciapaglia, G Lopalco, F Cardinale, F Iannone","doi":"10.4081/reumatismo.2024.1638","DOIUrl":"https://doi.org/10.4081/reumatismo.2024.1638","url":null,"abstract":"Objective: The indices to measure disease activity of chronic arthritis in adulthood and childhood are different. Therefore, assessing the status of the disease in young patients with juvenile idiopathic arthritis (JIA) can be tricky, especially when the transition to adult care is ongoing. The aim of our study was to assess the level of correlation between adult and juvenile scores in the measurement of disease activity in JIA patients during transitional care.Methods: We estimated the disease activity by using the Juvenile Arthritis Disease Activity Score 71 (JADAS71), clinical JADAS, adult Disease Activity Score (DAS28), Simplified Disease Activity Index (SDAI), and Clinical Disease Activity Index (CDAI) in JIA patients in transitional care. We enrolled patients older than 16 years at the time of the first transition visit, and disease activity was assessed at baseline and 12 months. Regression analyses were carried out to estimate the level of agreement among the different indices.Results: We recruited 26 patients with JIA; 11 patients were polyarticular (42.3%) and 15 patients were oligoarticular (53.1%). The mean age at diagnosis was 7.7±3.9 years and the age at the first evaluation was 20.9±3.7 years. The correlation between JADAS71 and DAS28 was r2=0.69, r2=0.86 between JADAS71 and SDAI, and r2=0.81 between JADAS71 and CDAI.Conclusions: SDAI and JADAS71 showed the best correlation, but a few patients were not captured at the same level of disease activity. New prospective studies with a larger number of patients will be needed in this field.","PeriodicalId":21222,"journal":{"name":"Reumatismo","volume":"76 2","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retention rate of abatacept in rheumatoid arthritis patients in a real-life setting: results from a monocentric cohort. 类风湿关节炎患者在现实生活中的阿巴他赛保留率：单中心队列的结果。

IF 1.2

Reumatismo Pub Date : 2024-06-24 DOI: 10.4081/reumatismo.2024.1608

E Molteni, C Pirone, F Ceccarelli, C Castellani, C Alessandri, M Di Franco, V Riccieri, F R Spinelli, R Priori, R Scrivo, F Conti

{"title":"Retention rate of abatacept in rheumatoid arthritis patients in a real-life setting: results from a monocentric cohort.","authors":"E Molteni, C Pirone, F Ceccarelli, C Castellani, C Alessandri, M Di Franco, V Riccieri, F R Spinelli, R Priori, R Scrivo, F Conti","doi":"10.4081/reumatismo.2024.1608","DOIUrl":"https://doi.org/10.4081/reumatismo.2024.1608","url":null,"abstract":"Objective: Data from trials demonstrated that abatacept (ABA) has a good safety and efficacy profile in treating rheumatoid arthritis. We have studied the retention rate of ABA in a real-life cohort of patients with rheumatoid arthritis.Methods: This is a monocentric, retrospective study including patients with rheumatoid arthritis classified by the American College of Rheumatology/European League Against Rheumatism 2010 criteria who started treatment with ABA. The Kaplan-Meier method was applied to evaluate the ABA retention rate.Results: This analysis was conducted on 161 patients [male/female 21/140, median age 65 years, interquartile range (IQR) 18.7, median disease duration 169 months, IQR 144.0]. 111 patients (68.9%) received ABA subcutaneously. ABA was associated with methotrexate in 61.9% of patients and was the first biological disease-modifying antirheumatic drug in 41%. We observed a median ABA survival of 66 months [95% confidence interval (CI) 57.3-74.7], with a retention rate of 88% at 6 months and 50.9% at 5 years. Drug survival was significantly higher in patients treated with ABA subcutaneously and in male patients (p=0.039 and p=0.018, respectively). Adjusted for main confounders, female gender was the main predictor of withdrawal (hazard ratio 5.1, 95% CI 1.2-21.3).Conclusions: Our study shows that better survival is associated with subcutaneous administration and male gender, confirming ABA effectiveness.","PeriodicalId":21222,"journal":{"name":"Reumatismo","volume":"76 2","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of nicotine smoking on spondyloarthritis and rheumatoid arthritis. 吸烟尼古丁对脊柱关节炎和类风湿性关节炎的影响。

IF 1.2

Reumatismo Pub Date : 2024-06-24 DOI: 10.4081/reumatismo.2024.1572

G El Hasbani, J E Nassar, A M Elsayed Ali, I Uthman, A Jawad

{"title":"The impact of nicotine smoking on spondyloarthritis and rheumatoid arthritis.","authors":"G El Hasbani, J E Nassar, A M Elsayed Ali, I Uthman, A Jawad","doi":"10.4081/reumatismo.2024.1572","DOIUrl":"https://doi.org/10.4081/reumatismo.2024.1572","url":null,"abstract":"Objective: Nicotine has major side effects on human health through numerous mechanisms, one of which is the alteration of the immune system and its genetic components. Such alteration can be a predisposing factor for autoimmune diseases such as spondyloarthritis (SpA) and rheumatoid arthritis (RA). This review aims to shed light on the effects of nicotine smoking on the pathophysiology, clinical presentation, and management of SpA and RA.Methods: This review looked into the studies, excluding case reports and series, which were cited by PubMed/MEDLINE.Results: Patients with established autoimmune conditions may have a different underlying pathophysiology and disease course when exposed to nicotine through cigarette smoking. Through the involvement of several cytokines, endothelial dysfunction, and epigenetic mechanisms, the severity of SpA is more prominent in smokers. The global health status, pain, and fatigue are worse in SpA patients. The evidence on the effect of nicotine smoking on the treatment of SpA is still limited. Nicotine can contribute to RA via the disruption of cellular regulatory activity, inflammatory responses, morphological, physiological, biochemical, and enzymatic responses. As such, smokers with RA have higher disease activity and are more likely to be seropositive through the citrullination of peptides. In addition, these patients are at risk of achieving a suboptimal response to tumor necrosis factor inhibitors.Conclusions: Cigarette smoking can substantially affect the pathophysiology and clinical presentation of patients with SpA and RA. The impact of nicotine on the management of these diseases still needs to be further studied.","PeriodicalId":21222,"journal":{"name":"Reumatismo","volume":"76 2","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The heterogeneity of lung involvement in vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic syndrome: a case of hypersensitivity pneumonitis-like pattern. 空泡、E1 酶、X 连锁、自身炎症、体质综合征肺部受累的异质性：一例超敏性肺炎样模式。

IF 1.2

Reumatismo Pub Date : 2024-06-24 DOI: 10.4081/reumatismo.2024.1611

C Iannone, M R Pellico, C Campochiaro, L Tescaro, M Zompatori, A Caminati, S Harari, R Caporali

引用次数: 0

Assessment of factors affecting quality of life in patients with chronic pain due to knee osteoarthritis and spondylosis: spine versus knee? 评估膝关节骨性关节炎和脊椎病引起的慢性疼痛患者生活质量的影响因素：脊柱还是膝关节？

IF 1.2

Reumatismo Pub Date : 2024-06-24 DOI: 10.4081/reumatismo.2024.1660

T Sahbaz, B Cigdem-Karacay

{"title":"Assessment of factors affecting quality of life in patients with chronic pain due to knee osteoarthritis and spondylosis: spine versus knee?","authors":"T Sahbaz, B Cigdem-Karacay","doi":"10.4081/reumatismo.2024.1660","DOIUrl":"https://doi.org/10.4081/reumatismo.2024.1660","url":null,"abstract":"Objective: There is no study comparing knee and spine osteoarthritis. The purpose of the study is to examine the effects of pain and disability on quality of life (QoL) and the factors affecting QoL in patients with knee osteoarthritis and spondylosis.Methods: This cross-sectional study included 114 patients with spondylosis and 126 patients with knee osteoarthritis. Demographic data were recorded. The visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Roland Morris Questionnaire (RMQ), and the Short Form Health Questionnaire (SF-36) were filled out.Results: Statistically, patients with spondylosis and knee osteoarthritis did not differ significantly in terms of gender, age, body mass index, number of concomitant conditions, marital status, years of schooling, pain scores, or SF-36 characteristics. SF-36 physical function, vitality, and mental health assessments were lower in women than men, while VAS scores were higher. There was no correlation between marital status, educational level, and QoL subscales. WOMAC and RMQ scores were negatively correlated with the SF-36 subscales. RMS scores were not related to mental health.Conclusions: Spondylosis and knee osteoarthritis affect all subscales of QoL in the same way. The management of patients with spondylosis and knee osteoarthritis should focus on pain and functionality to improve QoL.","PeriodicalId":21222,"journal":{"name":"Reumatismo","volume":"76 2","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between COMMD1 gene polymorphism rs11125908 and rheumatoid arthritis in the Cuban population. 古巴人群中 COMMD1 基因多态性 rs11125908 与类风湿性关节炎之间的关系。

IF 1.2

Reumatismo Pub Date : 2024-06-24 DOI: 10.4081/reumatismo.2024.1691

M Carpio Alvarez, A Cintado Benitez, T Diaz Argudin, H Nodarse Cuni, M D C Dominguez Horta, J R Fernández Massó

{"title":"Association between COMMD1 gene polymorphism rs11125908 and rheumatoid arthritis in the Cuban population.","authors":"M Carpio Alvarez, A Cintado Benitez, T Diaz Argudin, H Nodarse Cuni, M D C Dominguez Horta, J R Fernández Massó","doi":"10.4081/reumatismo.2024.1691","DOIUrl":"10.4081/reumatismo.2024.1691","url":null,"abstract":"Objective: To evaluate the association of the rs11125908 polymorphism in the COMMD1 gene in the Cuban population with rheumatoid arthritis (RA).Methods: In this case-control study, 161 RA patients and 150 control subjects were genotyped for rs11125908 by the allele-specific polymerase chain reaction method. DNA sequencing was used to verify the assignation of the polymorphism. The odds ratios (OR) and their 95% confidence interval were calculated by logistic regression to determine the associations between genotypes and RA using the SNPStats software.Results: An association of the single nucleotide polymorphism with the disease was found in the overdominant model (p=0.025; OR=1.91) for the AG genotype. Our analyses revealed an association between rs11125908 and the subgroup of patients with swollen joints < median under the codominant model for AG (p=0.034; OR=2.30) and GG genotype (p=0.034; OR=0.82) and with the overdominant model (p=0.01; OR=2.38). The subgroup of patients with an age of onset lower than the mean and AG genotype showed an association in the overdominant model (p=0.027; OR=2.27). Disease activity score 28 with erythrocyte sedimentation rate and disease duration variables were not associated with the rs11125908 polymorphism.Conclusions: rs11125908 was associated with RA and with the number of swollen joints and age of onset subgroup analyses. We provide concepts for treatments for RA, based on pharmacological management of COMMD1 expression.","PeriodicalId":21222,"journal":{"name":"Reumatismo","volume":"76 2","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel genetic mutation associated with hyperphosphatemic familial tumoral calcinosis/hyperostosis-hyperphosphatemia syndrome treated with denosumab: a case report. 与使用地诺单抗治疗高磷血症家族性肿瘤性钙化症/骨质疏松症-高磷血症综合征相关的新型基因突变：病例报告。

IF 1.2

Reumatismo Pub Date : 2024-06-24 DOI: 10.4081/reumatismo.2024.1687

G Fabbriciani, A Colombini, C Messina, G Adami

引用次数: 0

Rheumatic diseases in migrant patients resident in Tuscany: epidemiological data analysis and single-center experience. 居住在托斯卡纳的移民患者的风湿病：流行病学数据分析和单中心经验。

IF 1.4

Reumatismo Pub Date : 2024-03-22 DOI: 10.4081/reumatismo.2024.1547

L Cometi, P Francesconi, B Bellini, L Turco, F Voller, F Nacci, S Bellando-Randone, M Matucci-Cerinic, S Guiducci

{"title":"Rheumatic diseases in migrant patients resident in Tuscany: epidemiological data analysis and single-center experience.","authors":"L Cometi, P Francesconi, B Bellini, L Turco, F Voller, F Nacci, S Bellando-Randone, M Matucci-Cerinic, S Guiducci","doi":"10.4081/reumatismo.2024.1547","DOIUrl":"10.4081/reumatismo.2024.1547","url":null,"abstract":"Objective: In the last decades, the number of foreigners in Tuscany has considerably increased with a multiethnic distribution. We reviewed the main rheumatic diseases in the foreign population resident in Tuscany and also reported the experience at the Rheumatology Division of the University Hospital of Careggi, Florence, in order to identify the areas of origin of these patients and the main rheumatic diseases observed in them.Methods: The collaboration with the Tuscan Region provided data about foreign patients residing in Tuscany on January 1, 2021 (country of origin, chronic diseases). Moreover, we conducted a retrospective review of the clinical charts of our Rheumatologic Division from January 1, 2019, to December 31, 2020.Results: In Tuscany, on January 1, 2021, there were 61,373 patients with chronic inflammatory rheumatic diseases, and 3994 of them (6.51%) were foreigners. Most patients were born in Europe (39.03%), followed by the Balkans (15%), South America (11.27%), and North Africa (10.31%). Inflammatory joint diseases, Sjögren syndrome, and systemic lupus erythematosus were the most frequent diseases. In the period 2019-2020, 511 foreign patients visited our Rheumatology Division and mainly originated from the Balkans (34.64%), South America (18%), and European countries (16.44%). In these patients, chronic inflammatory joint diseases and connective tissue diseases (systemic sclerosis, Sjögren syndrome, and systemic lupus erythematosus) were the most prevalent diseases.Conclusions: This study provides a picture of the rheumatic diseases affecting foreign patients residing in Tuscany that are in agreement with the epidemiological data previously provided.","PeriodicalId":21222,"journal":{"name":"Reumatismo","volume":"76 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140207567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of diagnostic and therapeutic delay in patients with rheumatoid arthritis and psoriatic arthritis. 评估类风湿性关节炎和银屑病关节炎患者的诊断和治疗延迟。

IF 1.4

Reumatismo Pub Date : 2024-03-22 DOI: 10.4081/reumatismo.2024.1607

M Iacovantuono, S Ferrigno, P Conigliaro, P Triggianese, A D'Antonio, F R Spinelli, A Bergamini, M S Chimenti

{"title":"Evaluation of diagnostic and therapeutic delay in patients with rheumatoid arthritis and psoriatic arthritis.","authors":"M Iacovantuono, S Ferrigno, P Conigliaro, P Triggianese, A D'Antonio, F R Spinelli, A Bergamini, M S Chimenti","doi":"10.4081/reumatismo.2024.1607","DOIUrl":"10.4081/reumatismo.2024.1607","url":null,"abstract":"Objective: A monocentric cross-sectional study recruiting rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients residing in the Lazio region, Italy, to assess factors related to diagnostic delay and treatment accessibility.Methods: Clinical/serological data, including the time between symptom onset, diagnosis, and the beginning of treatment, were collected. Residence, referral to a rheumatologic center, physician who made the diagnosis, and previous misdiagnosis were also evaluated.Results: A higher diagnostic delay (p=0.003), and time between symptom onset and the start of I-line therapy (p=0.006) were observed in PsA compared to RA. A delayed start of II-line therapy was observed in RA compared to PsA (p=0.0007). Higher diagnostic delay (p=0.02), and time between symptom onset and the start of conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) (p=0.02) were observed among residents of small-medium cities for both groups. Patients who have been diagnosed by another physician rather than a rheumatologist had a longer diagnostic delay (p=0.034) and a delayed start of I-line therapy (p=0.019). Patients who received a different previous diagnosis experienced greater diagnostic delay (p=0.03 and p=0.003) and time of start of csDMARDs (p=0.05 and p=0.01) compared with those receiving RA or PsA as the first diagnosis. PsA had a delay in starting targeted synthetic disease-modifying anti-rheumatic drugs (p=0.0004) compared to RA. Seronegative RA had delayed diagnosis (p=0.02) and beginning of therapies (p=0.03; p=0.04) compared to seropositive ones.Conclusions: According to our results, greater diagnostic delay was found in PsA compared to RA, in patients living in small-medium cities, in those who did not receive the diagnosis from a rheumatologist, in those who were previously misdiagnosed, and in seronegative RA.","PeriodicalId":21222,"journal":{"name":"Reumatismo","volume":"76 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140207565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0