Revista da Sociedade Brasileira de Medicina Tropical最新文献

{"title":"Erratum.","authors":"","doi":"10.1590/0037-8682-0276B-2025","DOIUrl":"10.1590/0037-8682-0276B-2025","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/0037-8682-0276-2025].</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e0276B2025"},"PeriodicalIF":2.4,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13037721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New technologies for identification and surveillance of Chagas disease vectors.","authors":"Rodrigo Gurgel-Gonçalves, Genimar Rebouças Julião, Raquel Aparecida Ferreira, Rita de Cássia Moreira de Souza, Mirko Rojas-Cortez, Thallyta Maria Vieira, Vinícius Lima de Miranda, Jonas Lotufo Brant, Marcos Takashi Obara, Rafaella Albuquerque E Silva, Ana Karina Ibarrola-Vannucci, Gerardo Marti, Soledad Ceccarelli","doi":"10.1590/0037-8682-0597-2025","DOIUrl":"10.1590/0037-8682-0597-2025","url":null,"abstract":"<p><p>Technologies are essential for surveillance of vector-borne diseases. The increasing frequency of triatomine house invasion in the Americas highlights the need to strengthen surveillance strategies. This narrative review examines how emerging technologies can improve identification and reporting of Chagas disease vectors. We analyzed studies published between 2015 and 2025 on digital tools for triatomine surveillance. Technologies were grouped by purpose: (1) identification apps (TriatoKey, TriatoDex, automated identification); (2) community engagement platforms (WhatsBarb, TriatoChat); and (3) institutional surveillance systems (SISVetor-Chagas, GeoVin, Triatomine Information Posts). We summarize their characteristics, applications, knowledge gaps, and potential integration with national surveillance systems, and discuss implications for public health policy. Digital innovation and citizen-based surveillance may support improved prevention and control of vector-borne Chagas disease.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e05972025"},"PeriodicalIF":2.4,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13035241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors associated with dengue lethality: case-control study, Joinville, Brazil.","authors":"Romana Pedott Apel, Saulo Vicente Rocha, Dorceli Alves Lemes da Cruz, Juliana Antunes Safanelli, Helbert do Nascimento Lima","doi":"10.1590/0037-8682-0165-2025","DOIUrl":"10.1590/0037-8682-0165-2025","url":null,"abstract":"<p><strong>Background: </strong>Dengue remains a major public health concern in Brazil, with approximately 6 million cases and over 6,000 deaths reported in 2024. Joinville, in southern Brazil, recorded one of the highest incidence rates in the country. Understanding the clinical and demographic factors associated with dengue-related mortality in this region is essential for developing effective interventions.</p><p><strong>Methods: </strong>We conducted a retrospective matched case-control study using data from the Sistema de Informação de Agravos de Notificação database, involving adult patients with dengue who presented with warning signs or severe disease and were treated within Joinville's public health system (Sistema Único de Saúde) between January 2021 and December 2024. Cases were defined as fatal outcomes, while controls were matched survivors. Univariate and multivariate logistic regression models were used to estimate mortality risk.</p><p><strong>Results: </strong>Among 454 patients, 116 (26%) were cases and 336 (74%) were controls. Lower mortality was associated with having ≥ 2 medical consultations (odds ratio [OR] = 0.20; 95% confidence interval [CI]: 0.10-0.51) and receiving intravenous hydration of ≥ 1 L (OR = 0.32; 95% CI: 0.14-0.72). Hypotension (OR = 3.06; 95% CI: 1.33-7.03), thrombocytopenia (OR = 2.47; 95% CI: 1.21-5.02), and lethargy or irritability (OR = 15.59; 95% CI: 6.50-37.38) were significantly associated with mortality.</p><p><strong>Conclusions: </strong>Early intravenous rehydration and repeated clinical evaluations were associated with reduced mortality. Close monitoring of patients with warning signs is crucial for improving outcomes in high-incidence settings.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e01652025"},"PeriodicalIF":2.4,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13037723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147691758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolving antimicrobial resistance patterns in group B streptococci: A five-year study in a high-risk pregnancy referral center in northeastern Brazil.","authors":"Jorhanna Isabelle Araújo de Brito Gomes, Suellen Bernardo de Queiroz, Carlos Gabriel Andrade Barbosa, Larissa Rodrigues Santos Silva, Patrícia Urquiza Lundgren, Eduardo Sergio Soares Sousa, Eloiza Helena Campana, Vinicius Pietta Perez","doi":"10.1590/0037-8682-0259-2025","DOIUrl":"10.1590/0037-8682-0259-2025","url":null,"abstract":"<p><strong>Background: </strong>Streptococcus agalactiae (commonly referred to as group B streptococci [GBS]) is a leading cause of neonatal infection. Surveillance of colonization in pregnant women and the use of intrapartum antibiotic prophylaxis (IAP) are the primary strategies for preventing early-onset GBS disease. The increasing rate of antibiotic resistance among GBS isolates is a concern for the effectiveness of IAP. Our study aimed to evaluate the prevalence of GBS colonization and characterize antimicrobial resistance patterns over a five-year period in a high-risk pregnancy referral center in Northeastern Brazil.</p><p><strong>Methods: </strong>This study was conducted from 2020 to 2024 and included pregnant women at 35-37-week gestation. GBS isolates from anal-vaginal swabs were identified and tested for susceptibility to penicillin or ampicillin, clindamycin, erythromycin, levofloxacin, and tetracycline. Isolates stored from 2021 to 2024 were further analyzed for the resistance genes mef(A), erm(A/TR), erm(B), tet(M), and tet(O).</p><p><strong>Results: </strong>Of 1469 anal-vaginal samples, the overall GBS colonization rate was 12%. All isolates were susceptible to either penicillin or ampicillin. The respective resistance rates for erythromycin, clindamycin, levofloxacin, and tetracycline were 23.6%, 9.3%, 5.4%, and 82.3%. The main determinant among macrolide-resistant isolates was mef(A), and tet(M) was the most frequent tetracycline resistance gene. Furthermore, we found that erythromycin resistance increased consistently over the five years, signaling a potential impact on clindamycin efficacy due to erm genes.</p><p><strong>Conclusions: </strong>Beta-lactams (penicillin and ampicillin) remained effective for IAP in northeastern Brazil during the study period. However, high and increasing resistance to other antibiotic classes reinforces the need for maternal GBS surveillance and ongoing antimicrobial resistance monitoring.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e0259"},"PeriodicalIF":2.4,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12971026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147434981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visceral Leishmaniasis in Southern Brazil: an overview of current epidemiology.","authors":"Bibiana Paula Dambrós, Amabilli de Souza Rosar, Patricia Hermes Stoco, Patricia Flávia Quaresma, Edmundo Carlos Grisard, Mario Steindel","doi":"10.1590/0037-8682-0240-2025","DOIUrl":"10.1590/0037-8682-0240-2025","url":null,"abstract":"<p><p>Visceral leishmaniasis (VL), caused by the protozoan parasite Leishmania (Leishmania) infantum, is transmitted in Brazil through the bites of female phlebotomine sandflies. Until 2008, no cases of autochthonous VL transmission were reported in the southern Brazilian states of Paraná (PR), Santa Catarina (SC), and Rio Grande do Sul (RS). The first case of canine VL (CVL) in RS was reported in 2008, followed by that of human VL (HVL) in 2009. Since then, CVL and HVL cases have emerged in 12 and five additional municipalities in the RS, respectively. In SC, CVL was first reported in Santa Catarina Island in 2010 and is now present in 44 of 89 localities. By 2014, CVL had appeared in western SC, with new cases reported in the midwestern and southern areas in 2021and 2024, respectively. Between 2017 and 2022, five autochthonous HVL cases were diagnosed in Florianópolis. In the PR, CVL was first reported in Foz do Iguaçu in 2012, followed by HVL in 2015. Although Lutzomyia longipalpis, the primary vector of L. infantum in Brazil, has been found in certain municipalities of RS and PR, it has not been reported in other endemic or vulnerable areas of RS and SC. This suggests that other sandfly species may also contribute to disease transmission. This highlights the urgent need for research on the diversity of hosts, vectors, and parasite strains, along with enhanced epidemiological surveillance to clarify the transmission dynamics of VL in these regions.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e02402025"},"PeriodicalIF":2.4,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12990785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oropouche fever in Minas Gerais, Brazil, 2024: Epidemiological characterization, spatial distribution, and clinical implications.","authors":"Edmundo Rinolino Magalhães Flores, Flavia Ribeiro Soares Cruzeiro, Iara Fabíola Rocha, Caroline Macedo Gonçalves, Thais Cristina Nazaré Freitas, Daniela Caldas Teixeira","doi":"10.1590/0037-8682-0109-2025","DOIUrl":"10.1590/0037-8682-0109-2025","url":null,"abstract":"<p><strong>Background: </strong>Oropouche fever (OF), caused by the Oropouche virus (OROV), has historically been endemic to the Amazon region; however, it is now emerging in other Brazilian states. This study describes the sociodemographic, clinical, and spatial characteristics of OROV cases identified in Minas Gerais in 2024 and contributes to the understanding of its transmission dynamics in non-endemic regions.</p><p><strong>Methods: </strong>This descriptive epidemiological study used the official surveillance data from the State Health Department of Minas Gerais (SES/MG). The confirmed cases were those with laboratory-confirmed OROV infection by RT-PCR at the Ezequiel Dias Foundation (FUNED). Demographic, geographic, and clinical data were analyzed using descriptive statistics. Exploratory comparisons by sex and age were performed.</p><p><strong>Results: </strong>A total of 278 confirmed autochthonous cases were reported across 10 municipalities, primarily in rural and peri-urban areas. Women accounted for 55.0% of the cases, with the highest incidence among adults aged 20-59 years. Two temporal peaks were observed at epidemiological weeks 15 and 50, corresponding to distinct clusters in Joanésia and Piau, respectively. Symptom recurrence occurred in 25.5% of the cases. Headache, myalgia, gastrointestinal symptoms, dysgeusia, pruritus, and skin lesions were more common in women than in men. Hypertension and diabetes mellitus were the most common comorbidities. More than half the participants reported the presence of domestic animals nearby.</p><p><strong>Conclusions: </strong>This study confirmed the geographic expansion of OROV in southeastern Brazil and identified distinct temporal and spatial transmission patterns. These findings underscore the importance of strengthened arbovirus surveillance, improved laboratory capacity, and integrated vector control strategies.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e01092025"},"PeriodicalIF":2.4,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12990782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trypanosoma cruzi infection status in birthing individuals in three endemic provinces of Argentina: a descriptive cross-sectional study.","authors":"María Ayelen Toscani, Emmaria Danesi, Karen Klein, Luz Gibbons, Candela Belén Stella, Pablo Elías Gulayin, Mabel Berrueta, Eric Dumonteil, Claudia Herrera, Pierre Buekens, María Luisa Cafferata","doi":"10.1590/0037-8682-0328-2025","DOIUrl":"10.1590/0037-8682-0328-2025","url":null,"abstract":"<p><strong>Background: </strong>Chagas disease remains a public health challenge with underexplored prevalence and diagnosis in endemic areas. We assessed Trypanosoma cruzi infection screening among birthing individuals in three endemic provinces in northern Argentina.</p><p><strong>Methods: </strong>T. cruzi-seropositive birthing individuals with at least one positive or indeterminate test were enrolled during the postpartum period to confirm seropositivity by indirect hemagglutination (IHA) and enzyme-linked immunosorbent (ELISA) assays.</p><p><strong>Results: </strong>Among 40,035 deliveries, the T. cruzi infection rate was 1.9%. Confirmatory serology revealed 77.6% positivity, 9.3% negativity, and 13.0% discordance.</p><p><strong>Conclusions: </strong>These findings highlight the need for confirmatory testing and improved diagnostic strategies in endemic regions.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e03282025"},"PeriodicalIF":2.4,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12990784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pure neural leprosy in a child: case report and diagnostic challenges.","authors":"Hortência Aparecida Dos Reis Santana, Isabela Pedra Diamantino, Jean Carlos de Araújo Arruda, Pedro Alysson Mota da Silva, Gabrieli Souza Dos Santos, Jonatas César Matos de Oliveira, Vanessa Oliveira de Souza, Clécio Ribeiro Costa, Andrea Pereira Macke, Karen Nepomuceno Sá Teles, Fernando do Prado Vieira, Filipe Rocha Lima, Jonilson Berlink Lima","doi":"10.1590/0037-8682-0158-2025","DOIUrl":"10.1590/0037-8682-0158-2025","url":null,"abstract":"<p><p>Pure neural leprosy (PNL) is infrequent and manifests exclusively in the peripheral nerves without skin involvement, making the diagnosis more complex. We report the case of a 10-year-old child with muscle atrophy and sensory loss, diagnosed through clinical evaluation, grade 2 disability, and a positive anti-PGL-I test. The slit-skin smear (SSS) was negative for acid-fast bacilli. After 12 months of multidrug therapy, esthesiometric sensitivity improved; however, neurological deficits persisted, requiring anti-inflammatory treatment and physiotherapy. This case highlights the importance of early diagnosis and treatment for preventing disabilities. Tools, such as anti-PGL-I tests and imaging, are crucial, particularly in resource-limited settings.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e01582025"},"PeriodicalIF":2.4,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12990783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous infection caused by Mycobacterium chelonae in an immunocompromised individual.","authors":"Lucas Benício Dos Santos, Rafael Henrique Bento Elizeu, Lida Jouca de Assis Figueredo, Élida Aparecida Leal, Silvana Spíndola de Miranda","doi":"10.1590/0037-8682-0514-2025","DOIUrl":"10.1590/0037-8682-0514-2025","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e05142025"},"PeriodicalIF":2.4,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12990781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Reversed Halo Sign: A Rare Presentation of Legionella Pneumonia.","authors":"Alexandre Dias Mançano, Gláucia Zanetti, Edson Marchiori","doi":"10.1590/0037-8682-0565-2025","DOIUrl":"10.1590/0037-8682-0565-2025","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"59 ","pages":"e0565"},"PeriodicalIF":2.4,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12922512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146228417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}