Flavia Mazzoli-Rocha, Clara Pinto Diniz, Daniel Pereira Redes de Rezende, F. S. Mendes, A. Hasslocher-Moreno, A. Sousa, Roberto Magalhães Saraiva, A. Borghi-Silva, M. Mediano, D. Alexandre
{"title":"Inspiratory Muscle Strength in Chagas Cardiomyopathy: A Systematic Scoping Review","authors":"Flavia Mazzoli-Rocha, Clara Pinto Diniz, Daniel Pereira Redes de Rezende, F. S. Mendes, A. Hasslocher-Moreno, A. Sousa, Roberto Magalhães Saraiva, A. Borghi-Silva, M. Mediano, D. Alexandre","doi":"10.1590/0037-8682-0389-2023","DOIUrl":"https://doi.org/10.1590/0037-8682-0389-2023","url":null,"abstract":"ABSTRACT The increase in inflammatory markers associated with persistent chronic fibrosing myocarditis, a characteristic of chronic Chagas disease, can result in a reduction in inspiratory muscle strength (IMS) in Chagas cardiomyopathy (CC). However, literature in this field is still scarce. This review aimed to map and summarize the evidence regarding IMS in patients with CC. The inclusion criteria included reports with adult participants with a CC diagnosis, with or without heart failure (HF). The core concept examined was the maximum inspiratory pressure evaluated in the untrained and trained groups in the pre-training period. The context was open, including but not limited to hospitals and health centers. Two authors independently identified eligible studies and extracted the data. Descriptive synthesis was used as the primary strategy for analyzing the results. Nine studies (five clinical trials, three cross-sectional, and one cohort) were included. The CC classification differed among the studies, with no mention of HF in five and no CC staging specification in six. IMS was assessed using a manovacuometer, and only six studies analyzed and interpreted the data concerning the predicted values. The CC population with HF appeared to have impaired IMS. All studies involved only Brazilian volunteers. In conclusion, randomized clinical trials evaluating IMS and the effects of inspiratory muscle training need to be conducted to better understand the prevalence and risk of inspiratory muscle weakness in the CC population, as well as the effects of training. Such studies should be conducted at different stages of CC in different populations and countries.","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"76 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138587046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rodrigo Corrêa de Oliveira (★1956 †2023)","authors":"Juliana Gomes, Olindo de Assis Martins-Filho","doi":"10.1590/0037-8682-0547-2023","DOIUrl":"https://doi.org/10.1590/0037-8682-0547-2023","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"38 9","pages":""},"PeriodicalIF":2.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138588889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. A. Almeida, F. S. Mendes, A. N. Ramos Júnior, A. Sousa, T. B. S. Pavan, M. Mediano, A. L. Ostermayer, A. Hasslocher-Moreno, C. Britto, Christina T G Novaes, Dalmo Correia, F. Santos, G. M. S. Silva, Marisa Liliana Fernandez, Mayara Maia Lima, Noêmia Barbosa de Carvalho, O. C. Moreira, P. Albajar-Viñas, Ruth Moreira Leite, Swamy Lima Palmeira, Veruska Maia da Costa, M. A. Yasuda
{"title":"Guidelines for Trypanosoma cruzi-HIV Co-infection and other Immunosuppressive Conditions: Diagnosis, Treatment, Monitoring, and Implementation from the International Network of Care and Studies - 2023","authors":"E. A. Almeida, F. S. Mendes, A. N. Ramos Júnior, A. Sousa, T. B. S. Pavan, M. Mediano, A. L. Ostermayer, A. Hasslocher-Moreno, C. Britto, Christina T G Novaes, Dalmo Correia, F. Santos, G. M. S. Silva, Marisa Liliana Fernandez, Mayara Maia Lima, Noêmia Barbosa de Carvalho, O. C. Moreira, P. Albajar-Viñas, Ruth Moreira Leite, Swamy Lima Palmeira, Veruska Maia da Costa, M. A. Yasuda","doi":"10.1590/0037-8682-0549-2023","DOIUrl":"https://doi.org/10.1590/0037-8682-0549-2023","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"80 10","pages":""},"PeriodicalIF":2.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138586853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MD. Jobson Lopes de Oliveira, Igor Albuquerque Nogueira, J. K. Amaral, Luciana Ribeiro Campos, Mariana Macêdo, Militão Mendonça, Marília de Brito, Luciano Pamplona de Góes Cavalcanti, Robert T. Schoen
{"title":"Extra-articular Manifestations of Chikungunya","authors":"MD. Jobson Lopes de Oliveira, Igor Albuquerque Nogueira, J. K. Amaral, Luciana Ribeiro Campos, Mariana Macêdo, Militão Mendonça, Marília de Brito, Luciano Pamplona de Góes Cavalcanti, Robert T. Schoen","doi":"10.1590/0037-8682-0341-2023","DOIUrl":"https://doi.org/10.1590/0037-8682-0341-2023","url":null,"abstract":"ABSTRACT Chikungunya fever (CHIK) is a neglected tropical disease associated with chronic arthritis. CHIK is usually a self-limiting condition; however, extra-articular manifestations present as atypical illness in a minority of patients. These atypical features may mimic other conditions and potentially distract physicians from the true diagnosis. This review analyzes the evidence of many unusual extra-articular manifestations reported in cases of CHIK. Depending on the affected system, these unusual manifestations include encephalitis, myocarditis, acute interstitial nephritis, cutaneous manifestations, acute anterior uveitis, abdominal pain, and depression. In addition, coinfections and comorbidities may cause atypical illness and obscure the diagnosis. Further studies are required to clarify the pathophysiology and natural history of CHIK, as it remains a burdening condition. Exploring its atypical symptoms may be the missing scientific piece of this puzzle.","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"22 9","pages":""},"PeriodicalIF":2.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138589837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ricardo Alexandre Arcêncio, Erica Chimara, José Roberto Lapa E Silva, Julio Croda, Anna Cristina Calçada Carvalho
{"title":"Research, Innovation, and National Production of Strategic Inputs for Tuberculosis Elimination in Brazil: Contributions from the REDE-TB.","authors":"Ricardo Alexandre Arcêncio, Erica Chimara, José Roberto Lapa E Silva, Julio Croda, Anna Cristina Calçada Carvalho","doi":"10.1590/0037-8682-0518-2023","DOIUrl":"10.1590/0037-8682-0518-2023","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"56 ","pages":"e0518"},"PeriodicalIF":2.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ciguatera on the coast of Northeastern Brazil: report of an outbreak in Fernando de Noronha Archipelago.","authors":"Vidal Haddad Junior, Sandra Lia Chioro Dos Reis","doi":"10.1590/0037-8682-0404-2023","DOIUrl":"10.1590/0037-8682-0404-2023","url":null,"abstract":"an intoxication resulting from the consumption of marine fish contaminated by a neurotoxin (ciguatoxin) produced by dinoflagellates (protists), especially the species Gambierdiscus toxicus . It binds to sodium channels, causing a neuromuscular blockade","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"56 ","pages":"e04042023"},"PeriodicalIF":2.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138452333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pâmela Cristina Gaspar, Jane Rowley, Ana Roberta Pati Pascom, Eline Korenromp, Fernando Pascual, Gerson Fernando Mendes Pereira, Angelica Espinosa Miranda
{"title":"Gonorrhea prevalence in adults in Brazil: Spectrum-STI trend estimation, 2000-2020.","authors":"Pâmela Cristina Gaspar, Jane Rowley, Ana Roberta Pati Pascom, Eline Korenromp, Fernando Pascual, Gerson Fernando Mendes Pereira, Angelica Espinosa Miranda","doi":"10.1590/0037-8682-0203-2023","DOIUrl":"10.1590/0037-8682-0203-2023","url":null,"abstract":"<p><strong>Background: </strong>Gonorrhea is not a notifiable disease in Brazil, and the national health information system does not collect data on reported cases or infection prevalence.</p><p><strong>Methods: </strong>We compiled published data on gonorrhea prevalence in Brazil from cross-sectional surveys and clinical trials between 2000 and 2020. The study entry criteria included a sample size of 50 or more, and Neisseria gonorrhoeae infection detected in urine, urethral, anal, or cervicovaginal specimens using either Nucleic Acid Amplification Test or culture. Gonorrhea prevalence trends between 2000 and 2020 were generated using Spectrum-STI, a statistical trend-fitting model.</p><p><strong>Results: </strong>Forty-five studies with 59 gonorrhea prevalence data points were identified. Fifty data points were for women and represented 21,815 individuals, eight for men encompassing a total of 4,587 individuals, and one for transgender people comprising 345 individuals. The Spectrum-STI estimate for the prevalence of urogenital infection with gonorrhea in women 15-49 in 2020 was 0.63% (95% confidence interval (CI): 0.13-2.23) and was lower than the 1.05% estimated value for 2000 (95% CI: 0.36-2.79). The corresponding figures for men were 0.70% (95% CI: 0.16-2.44) and 1.14% (95% CI: 0.34-3.15). Anal prevalence estimates could not be generated because of insufficient data (three data points).</p><p><strong>Conclusions: </strong>These results suggest that the overall prevalence of genitourinary gonococcal infections in Brazil is less than 1%. Data on gonorrhea prevalence in men and in populations at increased STI vulnerability are limited.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"56 ","pages":"e02032023"},"PeriodicalIF":2.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138452334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fábio Henrique Kwasniewski, Emanuel Marques da Silva, Edmarlon Girotto, Denise Maria Candido, Miriam de Cássia Tóffolo, Daniel Emilio Dalledone Siqueira, Luiz Roberto Costa Gomes, Camilo Molino Guidoni
{"title":"First report of an accident caused by Jaguajir agamemnon (C.L. Koch, 1839) (Scorpiones, Buthidae) in Paraná state, Brazil.","authors":"Fábio Henrique Kwasniewski, Emanuel Marques da Silva, Edmarlon Girotto, Denise Maria Candido, Miriam de Cássia Tóffolo, Daniel Emilio Dalledone Siqueira, Luiz Roberto Costa Gomes, Camilo Molino Guidoni","doi":"10.1590/0037-8682-0286-2023","DOIUrl":"https://doi.org/10.1590/0037-8682-0286-2023","url":null,"abstract":"<p><p>We report the first pediatric case of a Jaguajir agamemnon scorpion sting. This case occurred in the state of Paraná and is the first record of this species in southern Brazil. The patient was admitted within 15 min, with pain, local edema, erythema, whole-body pruritus, and tongue paresthesia within the first two hours, which disappeared thereafter. The patient's condition was considered mild, with a positive outcome, and she recovered completely.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"56 ","pages":"e02862023"},"PeriodicalIF":2.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71426416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nayara Ragi Baldoni, Nayara Dornela Quintino, Claudia Di Lorenzo Oliveira, José Luiz Padilha da Silva, Ariela Mota Ferreira, Antonio Luiz Pinho Ribeiro, Ester Cerdeira Sabino, Clareci Silva Cardoso
{"title":"Chagas disease and perceived quality of life: a cross-sectional study.","authors":"Nayara Ragi Baldoni, Nayara Dornela Quintino, Claudia Di Lorenzo Oliveira, José Luiz Padilha da Silva, Ariela Mota Ferreira, Antonio Luiz Pinho Ribeiro, Ester Cerdeira Sabino, Clareci Silva Cardoso","doi":"10.1590/0037-8682-0206-2023","DOIUrl":"10.1590/0037-8682-0206-2023","url":null,"abstract":"<p><strong>Background: </strong>Chagas disease (ChD) is a neglected tropical disease that is caused by the protozoan parasite Trypanosoma cruzi and can negatively impact quality of life (QoL). This study aimed to assess and compare QoL between individuals with and without ChD.</p><p><strong>Methods: </strong>This cross-sectional study was performed within a concurrent cohort study (REDS). The participants were derived from two blood donation centers: São Paulo capital and Montes Claros, Minas Gerais, Brazil. Participants with ChD were identified in blood donations by serological diagnosis between 2008 and 2010, and those without ChD were donors with negative serology identified during the same period. QoL was assessed using the World Health Organization Quality of Life-BREF questionnaire. Logistic regression was used to compare sociodemographic and clinical characteristics between the groups, and mean, standard deviation, and beta regression were used to compare QoL.</p><p><strong>Results: </strong>In total, 611 individuals participated in the study (328 with ChD and 283 without ChD). Participants with ChD had lower QoL in the physical (p=0.02) and psychological (p<0.01) domains than did individuals without CD.</p><p><strong>Conclusions: </strong>Individuals with ChD had worse QoL perceptions. These results provide a comprehensive understanding of the impact of ChD on individuals' QoL, while also highlighting potential opportunities for improving the care and treatment of those affected.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"56 ","pages":"e02062023"},"PeriodicalIF":2.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71426414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Th17 Cells and Cytokines in Leprosy: Understanding the Immune Response and Polarization.","authors":"Larissa Marchi Zaniolo, Amílcar Sabino Damazo","doi":"10.1590/0037-8682-0265-2023","DOIUrl":"https://doi.org/10.1590/0037-8682-0265-2023","url":null,"abstract":"<p><p>While there are conflicting data concerning interleukin (IL)-17 levels in the serum of patients with leprosy compared with those in healthy controls, higher levels have been more evident in the tuberculoid clinical form of leprosy and type 1 reactions. This review aimed to highlight the role of Th17 cells and their cytokines in leprosy. Cytokines such as IL-1β and IL-23 induce Th17, while transforming growth factor beta and IL-10 inhibit Th17, indicating that the balance between Th17 and regulatory T cells is crucial for leprosy polarization. However, more comprehensive paired studies are required to better elucidate the role of Th17 cells in leprosy.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"56 ","pages":"e02652023"},"PeriodicalIF":2.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71426428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}