María Ayelen Toscani, Emmaria Danesi, Karen Klein, Luz Gibbons, Candela Belén Stella, Pablo Elías Gulayin, Mabel Berrueta, Eric Dumonteil, Claudia Herrera, Pierre Buekens, María Luisa Cafferata
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引用次数: 0
Abstract
Background: Chagas disease remains a public health challenge with underexplored prevalence and diagnosis in endemic areas. We assessed Trypanosoma cruzi infection screening among birthing individuals in three endemic provinces in northern Argentina.
Methods: T. cruzi-seropositive birthing individuals with at least one positive or indeterminate test were enrolled during the postpartum period to confirm seropositivity by indirect hemagglutination (IHA) and enzyme-linked immunosorbent (ELISA) assays.
Results: Among 40,035 deliveries, the T. cruzi infection rate was 1.9%. Confirmatory serology revealed 77.6% positivity, 9.3% negativity, and 13.0% discordance.
Conclusions: These findings highlight the need for confirmatory testing and improved diagnostic strategies in endemic regions.
期刊介绍：
The Journal of the Brazilian Society of Tropical Medicine (JBSTM) isan official journal of the Brazilian Society of Tropical Medicine) with open access. It is amultidisciplinary journal that publishes original researches related totropical diseases, preventive medicine, public health, infectious diseasesand related matters. Preference for publication will be given to articlesreporting original observations or researches. The journal has a peer-reviewsystem for articles acceptance and its periodicity is bimonthly. The Journalof the Brazilian Society of Tropical Medicine is published in English.The journal invites to publication Major Articles, Editorials, Reviewand Mini-Review Articles, Short Communications, Case Reports, TechnicalReports, Images in Infectious Diseases, Letters, Supplements and Obituaries.
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