Fernando Tobias Silveira, Luciana Vieira Lima, Patrícia Karla Ramos, Marliane Batista Campos
{"title":"Is it plausible that Lutzomyia longipalpis (Psychodidae: Phlebotominae) waited until European colonizers introduced Leishmania (L.) infantum to the New World to become a vector of American visceral leishmaniasis? An Opinion.","authors":"Fernando Tobias Silveira, Luciana Vieira Lima, Patrícia Karla Ramos, Marliane Batista Campos","doi":"10.1590/0037-8682-0447-2024","DOIUrl":"10.1590/0037-8682-0447-2024","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e011012025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisany Krug Mareto, Sahra de Almdeira Metzker, Camila Guadeluppe Maciel, Bruna Luiza de Amorin Vilharba, Fabio Antonio Venancio, Wagner de Souza Fernandes, Cláudia Du Bocage Santos-Pinto, Everton Falcão de Oliveira
{"title":"Investigating the association between yellow fever vaccination and symptomatic acute Zika virus infection: a case-control study.","authors":"Lisany Krug Mareto, Sahra de Almdeira Metzker, Camila Guadeluppe Maciel, Bruna Luiza de Amorin Vilharba, Fabio Antonio Venancio, Wagner de Souza Fernandes, Cláudia Du Bocage Santos-Pinto, Everton Falcão de Oliveira","doi":"10.1590/0037-8682-0233-2024","DOIUrl":"10.1590/0037-8682-0233-2024","url":null,"abstract":"<p><strong>Background: </strong>During the Zika virus (ZIKV) epidemic in Latin America (2015-2016), a high incidence of microcephaly was observed in places with low yellow fever (YF) vaccination coverage. Cross-reactivity between ZIKV and YF virus was hypothesized as a possible explanation.</p><p><strong>Methods: </strong>We performed a case-control study to estimate the odds of ZIKV infection according to patients' YF vaccination status. The study considered ZIKV fever as the outcome, and previous vaccination against YF as exposure. We included all confirmed cases of acute ZIKV fever in Campo Grande, Mato Grosso do Sul, from January 2015 to December 2018. The control group comprised age- and sex-matched residents of Campo Grande who had no history of acute febrile arboviruses during the study period.</p><p><strong>Results: </strong>The cumulative incidence of acute ZIKV fever was 1.87 cases per 1000 population. The case group had a predominance of women aged 20-39 years and white and mixed races. Vaccination coverage for YF was 65.5% in the case group and 60.9% in the control group. The odds ratio (OR) suggested a weak association between outcomes and exposure (OR = 1.23; 95% confidence interval [CI]: 1.05-1.44).</p><p><strong>Conclusions: </strong>Our findings provide no evidence that prior YF vaccination protects against acute ZIKV infection. Further studies are needed to analyze the development of anti-ZIKV and anti-YF neutralizing antibodies in affected individuals because new ZIKV epidemics are predicted.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e004042025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noemia Barbosa Carvalho, Vera Lucia Teixeira de Freitas, Nadia Emi Aikawa, Lucas Teixeira Vieira, Rita Cristina Bezerra, Adriana Coraccini Tonácio de Proença, Karina Bonfiglioli, Érika Yoshie Shimoda Nakanishi, Hermes Ryoiti Higashino, Maria Aparecida Shikanai-Yasuda
{"title":"Quantitative PCR for parasitemia monitoring and preemptive therapy in patients with Chagas disease and autoimmune rheumatic disorders undergoing biologic treatment: a case series.","authors":"Noemia Barbosa Carvalho, Vera Lucia Teixeira de Freitas, Nadia Emi Aikawa, Lucas Teixeira Vieira, Rita Cristina Bezerra, Adriana Coraccini Tonácio de Proença, Karina Bonfiglioli, Érika Yoshie Shimoda Nakanishi, Hermes Ryoiti Higashino, Maria Aparecida Shikanai-Yasuda","doi":"10.1590/0037-8682-0419-2024","DOIUrl":"10.1590/0037-8682-0419-2024","url":null,"abstract":"<p><p>Patients with chronic Chagas disease (CD) and autoimmune rheumatic disorders (ARD) receiving immunosuppressive therapy are at risk for CD reactivation (CDR). This study monitored parasitemia over 9-121 months in six patients with CD and ARD using conventional and quantitative PCR and parasitology. Five patients showed parasitemia; two had elevated levels of parEq/mL (49-458.7). One patient received benznidazole with a marked decrease in parasitemia; in the other, treatment was discontinued after 12 days due to toxicity. No CDR occurred. These findings support the need for qPCR standardization for preemptive therapy and suggest that benznidazole may prevent CDR in patients with high parasitemia.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e008022025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Widespread Encephalitis Following Acute Sinusitis in a Pediatric Patient.","authors":"Elif Gozgec, Muhammed Mukremin Bugdaci","doi":"10.1590/0037-8682-0024-2025","DOIUrl":"10.1590/0037-8682-0024-2025","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e009202025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Crimean-Congo hemorrhagic fever with severe bradycardia treated with Theophylline.","authors":"Murat Aydın, Nurten Nur Aydın","doi":"10.1590/0037-8682-0416-2024","DOIUrl":"10.1590/0037-8682-0416-2024","url":null,"abstract":"<p><p>Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral hemorrhagic fever caused by Nairovirus and characterized by fever, myalgia, arthralgia, and hemorrhagic manifestations. Severe bradycardia is a rare complication of the disease. We present a 30-year-old male patient with CCHF who developed severe bradycardia, which was successfully treated with intravenous and oral theophylline. This case highlights the need to recognize cardiac complications in CCHF and highlights the role of pharmacological interventions in improving patient outcomes.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e008032025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leishmania (L.) amazonensis Lainson & Shaw, 1972: A cruel parasite causing a high-morbidity disease with severe physical deformities and, secondarily, even death.","authors":"Fernando Tobias Silveira","doi":"10.1590/0037-8682-0393-2024","DOIUrl":"10.1590/0037-8682-0393-2024","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e011022025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurten Nur Aydın, Murat Aydın, Deniz Öztürk Koçakgöl, Ömer Karaşahin
{"title":"Intracranial Tuberculomas Associated with Tuberculous Meningitis.","authors":"Nurten Nur Aydın, Murat Aydın, Deniz Öztürk Koçakgöl, Ömer Karaşahin","doi":"10.1590/0037-8682-0440-2024","DOIUrl":"10.1590/0037-8682-0440-2024","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e009212025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leonor Murça da Silva Balo, Howard Lopes Ribeiro Junior
{"title":"Ocular Filariasis caused by Loa loa infection.","authors":"Leonor Murça da Silva Balo, Howard Lopes Ribeiro Junior","doi":"10.1590/0037-8682-0044-2025","DOIUrl":"10.1590/0037-8682-0044-2025","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e009182025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucas Alves da Mota Santana, Michelly Kierkegaard Campos de Oliveira, Maria Vitória Conceição Carvalho, Pedro Henrique Macedo Moura, Marina Dos Santos Barreto, Marcos Antônio Lima Dos Santos, Pedro Lima Dos Santos, Dalmo Correia, Virgínia Kelma Dos Santos Silva, Rajiv Gandhi Gopalsamy, Cleverson Luciano Trento, Lysandro Pinto Borges, Wilton Mitsunari Takeshita
{"title":"Cytogenetic Alterations Observed in Exfoliative Cells of the Tongue and Oral Mucosa of SARS-CoV-2-Vaccinated Patients: Report of Two Cases and a Brief Literature Review.","authors":"Lucas Alves da Mota Santana, Michelly Kierkegaard Campos de Oliveira, Maria Vitória Conceição Carvalho, Pedro Henrique Macedo Moura, Marina Dos Santos Barreto, Marcos Antônio Lima Dos Santos, Pedro Lima Dos Santos, Dalmo Correia, Virgínia Kelma Dos Santos Silva, Rajiv Gandhi Gopalsamy, Cleverson Luciano Trento, Lysandro Pinto Borges, Wilton Mitsunari Takeshita","doi":"10.1590/0037-8682-0008-2025","DOIUrl":"10.1590/0037-8682-0008-2025","url":null,"abstract":"<p><p>The wide distribution of angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) in oral tissues, especially in the salivary glands, which are natural reservoirs of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), contributes to the classification of the oral cavity as a potential target for the development of lesions. Despite the effective response produced by next-generation immunizers, the possibility of immune escape by new lineages of SARS-CoV-2 cannot be refuted. Therefore, we describe here the occurrence of cytogenetic alterations in orally exfoliated cells of immunized individuals and, based on the literature review, call attention to the need to monitor these cases in the post-pandemic period.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e008042025"},"PeriodicalIF":1.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}