Revista alergia Mexico最新文献_第9页

[Basophil activation test as a helpful tool for the diagnostic and treatment of a case of anaphylaxis due to a preparation of depot testosterone]. [嗜碱性粒细胞激活试验作为诊断和治疗因储备睾酮制剂引起的过敏反应的有用工具]。

Revista alergia Mexico Pub Date : 2021-04-01 DOI: 10.29262/ram.v658i2.783

Felipe Santos-Vicente, Margarita Latasa-Eceizabarrena, Juan Luis Estrada-Rodríguez, Begoña Pérez-Corral, María Luisa Sanz-Larruga

{"title":"[Basophil activation test as a helpful tool for the diagnostic and treatment of a case of anaphylaxis due to a preparation of depot testosterone].","authors":"Felipe Santos-Vicente, Margarita Latasa-Eceizabarrena, Juan Luis Estrada-Rodríguez, Begoña Pérez-Corral, María Luisa Sanz-Larruga","doi":"10.29262/ram.v658i2.783","DOIUrl":"https://doi.org/10.29262/ram.v658i2.783","url":null,"abstract":"Introduction: In many cases of drug allergy, it is necessary to do in vitro test, for several reasons. BAT (basophil activation test) is a very useful weapon in these cases. In many iv. or im. depot preparations, the culprit of the allergic reaction is an excipient, and not the main component.Case report: A 37-year-old male, suffering from a Klinefelter syndrome needed treatment with a preparation of undecanoate of testosterone (Reandron). With the last administered dose, he suffered an anaphylactic shock with Kounis syndrome. The patient declined any in vivo studies, so we thought of BAT as a possibility for the diagnosis. The results were remarkable, showing a very high positivity to castor oil.Conclusions: This is the second case in the world of anaphylaxis to a preparation of Testosterone, and the first one with the castor oil (also called Cremophor or Kolliphor) as responsible. El BAT was essential for the diagnosis and ulterior treatment of this patient. This is the first time, that this study with BAT, has been done with a Testosterone preparation.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 2","pages":"140-143"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39418827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[Cutaneous manifestations in patients with COVID-19 with significant attention to urticaria]. 【COVID-19患者皮肤表现与荨麻疹密切相关】。

Revista alergia Mexico Pub Date : 2021-04-01 DOI: 10.29262/ram.v658i2.841

Mario Sánchez-Borges, Sandra Nora González-Díaz, José Antonio Ortega-Martell, María Isabel Rojo-Gutiérrez, Ignacio Javier Ansotegui-Zubeldia

{"title":"[Cutaneous manifestations in patients with COVID-19 with significant attention to urticaria].","authors":"Mario Sánchez-Borges, Sandra Nora González-Díaz, José Antonio Ortega-Martell, María Isabel Rojo-Gutiérrez, Ignacio Javier Ansotegui-Zubeldia","doi":"10.29262/ram.v658i2.841","DOIUrl":"https://doi.org/10.29262/ram.v658i2.841","url":null,"abstract":"Objectives: To describe the most frequent dermatological conditions observed in COVID-19 patients and to determine whether their presence could be used to establish an early diagnosis or to predict the progression of the infection.Methods: There was a review in PubMed/MEDLINE and EMBASE of all the articles that had been published between January 1st and November 1st, 2020, with the search terms focused on \"SARS-CoV-2\", \"COVID-19\" and \"Skin diseases\".Results: Eighty three studies met the inclusion criteria. Skin lesions have been reported in 0.2 % of the patients. The most frequently reported dermatoses were: maculopapular/ morbilliform rashes, urticaria and angioedema, chilblain-like acral pattern, and vesicular lesions. Among researchers, there are differences of opinion about a possible diagnostic or prognostic value of the skin diseases that are associated to the infection.Conclusions: It is advisable to consider the diagnosis of SARS-CoV-2 infection in patients who call the doctor for skin lesions, urticaria, or angioedema, with or without other symptoms of the infection, especially if there is a previous history of recent exposure to other infected subjects.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 2","pages":"112-116"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39418820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Prevalence of allergic rhinitis and associated factors in Mexican students. A multicenter study]. 墨西哥学生变应性鼻炎患病率及相关因素分析。多中心研究]。

Revista alergia Mexico Pub Date : 2021-04-01 DOI: 10.29262/ram.v658i2.786

Eleazar Mancilla-Hernández, Raúl Barnica, Evaristo González-Solórzano, José Alfredo Peregrina, Yahvé Zecua-Nájera, Gerardo Alberto Soberanes-Rivas, Jaime Omar Jiménez-Sandoval

{"title":"[Prevalence of allergic rhinitis and associated factors in Mexican students. A multicenter study].","authors":"Eleazar Mancilla-Hernández, Raúl Barnica, Evaristo González-Solórzano, José Alfredo Peregrina, Yahvé Zecua-Nájera, Gerardo Alberto Soberanes-Rivas, Jaime Omar Jiménez-Sandoval","doi":"10.29262/ram.v658i2.786","DOIUrl":"https://doi.org/10.29262/ram.v658i2.786","url":null,"abstract":"Objective: To determine the prevalence of allergic rhinitis and its associated factors in students from several Mexican states.Methods: A cross-sectional study was conducted in order to identify the factors that are associated with the prevalence of allergic rhinitis. The \"Allergic Rhinitis Diagnostic Questionnaire for Epidemiological Studies\" was used, together with another questionnaire, to identify risk factors in allergic rhinitis.Results: 11381 students of 12-24 years of age were included; the prevalence of allergic rhinitis was of 18 % (CI 95 % = 11.4-24.6), with predominance in females (60%). The factors associated with allergic rhinitis were: heredity, (OR = 2-4, p < 0.0001), respiratory infections, (OR = 2-4.6, p < 0.0001); areas with humidity at home (OR= 1.5 - 1.9, p < 0.0001), and being female (OR = 1.7 - 2.4, p < 0.002). The use of tobacco, the educational level and vehicular traffic, as well as carpeting and the use of scented disinfectants, showed no association.Conclusions: The factors associated with allergic rhinitis in students were; heredity, respiratory infections, humidity in house walls, and being female.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 2","pages":"101-111"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39418885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Chronic mucocutaneous candidiasis associated with autoimmunity and ectodermal dysplasia. A case report]. 慢性粘膜皮肤念珠菌病与自身免疫和外胚层发育不良有关。[病例报告]。

Revista alergia Mexico Pub Date : 2021-04-01 DOI: 10.29262/ram.v658i2.862

Miguel García-Domínguez, Hirad Hirad Pérez-Ávila, César Mauricio Rojas-Maruri, Ximena León-Lara, Eduardo Llausás-Magaña, Carlos García-Bueno, Lizbeth Blancas-Galicia

{"title":"[Chronic mucocutaneous candidiasis associated with autoimmunity and ectodermal dysplasia. A case report].","authors":"Miguel García-Domínguez, Hirad Hirad Pérez-Ávila, César Mauricio Rojas-Maruri, Ximena León-Lara, Eduardo Llausás-Magaña, Carlos García-Bueno, Lizbeth Blancas-Galicia","doi":"10.29262/ram.v658i2.862","DOIUrl":"https://doi.org/10.29262/ram.v658i2.862","url":null,"abstract":"Introduction: Chronic mucocutaneous candidiasis associated with autoimmunity and ectodermal dysplasia is an inborn error of immunity, characterized by a classic triad (chronic mucocutaneous candidiasis, hyperparathyroidism, and adrenal insufficiency) due to the presence of autoantibodies against different endocrine and non-endocrine organs; and it is predominant in Jews and Finns.Case report: A 7-year-old girl of European descent and positive consanguinity, with a personal history of recurrent respiratory infections, chronic candidiasis, pseudomembranous colitis, and pancytopenia. The clinical findings raised suspicions of an inborn error of immunity, and the accurate diagnosis of APECED (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy) was made by detecting a pathogenic variant in the AIRE gene through new- generation sequencing technologies.Conclusion: Nowadays, there is access to new genetic tools to establish an early diagnosis of the different inborn errors of immunity; thus, offering timely treatment and a better prognosis.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 2","pages":"144-149"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39418793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Anaphylaxis sugammadex-induced in a pediatric patient]. [1例儿科患者糖糖致过敏反应]。

Revista alergia Mexico Pub Date : 2021-04-01 DOI: 10.29262/ram.v658i2.876

Juana Bautista Joyanes-Romo, Ana Isabel Navarro-Abad, José Miguel Urra-Ardanaz, Óscar González-Jiménez, Alberto Palacios, Jaime Vinicio Meneses-Sotomayor, Marta Pascual, Ma Gracia Villanueva, Davinia Garrido, Ana Joyanes, Pedro Ángel Galindo-Bonilla

{"title":"[Anaphylaxis sugammadex-induced in a pediatric patient].","authors":"Juana Bautista Joyanes-Romo, Ana Isabel Navarro-Abad, José Miguel Urra-Ardanaz, Óscar González-Jiménez, Alberto Palacios, Jaime Vinicio Meneses-Sotomayor, Marta Pascual, Ma Gracia Villanueva, Davinia Garrido, Ana Joyanes, Pedro Ángel Galindo-Bonilla","doi":"10.29262/ram.v658i2.876","DOIUrl":"https://doi.org/10.29262/ram.v658i2.876","url":null,"abstract":"Introduction: Sugammadex is a cyclodextrin that reverses neuromuscular blockade, especially of rocuronium. The occurrence of anaphylaxis produced by its use is of 1:1000 and 1:20000; it is observed mainly in subjects of Asian origin.Case report: A 9-year-old boy of Asian origin who, after the administration of sugammadex, immediately manifested an episode of anaphylaxis, which was reverted by using adrenaline and antihistamines. The serum tryptase at two hours was 27.7 μg/L; at 6 weeks, it was 3 μ/L. The sugammadex 100 mg/mL skin test was positive. The basophil activation test was positive with sugammadex 20 mg/mL.Conclusion: The temporal relationship between the administration of the drug, the clinical manifestations, the elevation of tryptase, and the diagnostic tests performed, disclosed the episode of anaphylaxis associated with hypersensitivity to sugammadex.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 2","pages":"137-139"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39418822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

[Statistical methods for effect size analysis]. [效应量分析的统计方法]。

Revista alergia Mexico Pub Date : 2021-04-01 DOI: 10.29262/ram.v658i2.949

Mario Enrique Rendón-Macías, Irma Susana Zarco-Villavicencio, Miguel Ángel Villasís-Keever

引用次数: 4

[Correlation between interleukin 4 (IL-4) expression and allergen sensitization in allergic rhinitis patients]. [变应性鼻炎患者白细胞介素4 (IL-4)表达与过敏原致敏的相关性]。

Revista alergia Mexico Pub Date : 2021-04-01 DOI: 10.29262/ram.v658i2.800

Asti Widuri

{"title":"[Correlation between interleukin 4 (IL-4) expression and allergen sensitization in allergic rhinitis patients].","authors":"Asti Widuri","doi":"10.29262/ram.v658i2.800","DOIUrl":"https://doi.org/10.29262/ram.v658i2.800","url":null,"abstract":"Objective: The objective of this research was to measure the correlation of the expression of IL-4 with allergen sensitization in patients with allergic rhinitis.Methods: Descriptive analytics was used as a method in this research, with a cross-sectional approach. The subjects were 37 persons with allergic rhinitis who met the inclusion and exclusion criteria. This research was conducted in patients with clinical manifestations of symptoms of allergic rhinitis, and skin prick tests were carried out with ten types of allergens, which are: house dust, cotton, chicken feathers, shrimp, tuna, chicken egg-yolk, chicken egg-white, peanuts, tea, and chocolate. Venous blood sampling was performed for the Interleukin-4 (IL-4) test by using an ELISA device.Results: The respondents were 37 patients with allergic rhinitis, of which 26 (70.3 %) were women and 11 (29.7 %) were men. The highest sensitivity to inhaled allergens in patients with rhinitis was to house dust in 31 samples (83.8 %). The correlation of the expression of IL-4 with sensitization to allergens in patients with allergic rhinitis based on the Spearman test resulted in p > 0.05, not significant with some allergens in a negative correlation.Conclusion: There was no significant correlation between the expression of IL-4 and the sensitization to allergens in patients with allergic rhinitis.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 2","pages":"89-93"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39418886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Mycobacterial disease in patients with chronic granulomatous disease]. 【慢性肉芽肿病患者的分枝杆菌病】。

Revista alergia Mexico Pub Date : 2021-04-01 DOI: 10.29262/ram.v658i2.859

Beatriz García, Ximena León-Lara, Sara Espinosa, Lizbeth Blancas-Galicia

{"title":"[Mycobacterial disease in patients with chronic granulomatous disease].","authors":"Beatriz García, Ximena León-Lara, Sara Espinosa, Lizbeth Blancas-Galicia","doi":"10.29262/ram.v658i2.859","DOIUrl":"https://doi.org/10.29262/ram.v658i2.859","url":null,"abstract":"Chronic granulomatous disease (CGD) is an inborn error of immunity that affects the functionality of phagocytosis; specifically, there's lack of production of oxygen-free radicals by NADPH oxidase. CGD manifests as severe and recurring bacterial and fungal infections, as well as local and systemic hyperinflammation. In countries where tuberculosis is endemic and the BCG vaccine is mandatory at birth, patients with CGD may present local or systemic reactions to this vaccine as first manifestation; besides, recurrent infections by M. tuberculosis may be present throughout their life. The susceptibility of these patients to mycobacteria is due to the excessive production of pro-inflammatory cytokines and the formation of granulomas that are inefficient in containing mycobacteria. In developed countries, patients with CGD do not present this type of infectious manifestations, except for migrants who come from developing countries. In this review, we present the characteristics of infections by BCG, M. tuberculosis, and other types of mycobacteria. Interestingly, there are no guidelines regarding anti-tuberculosis treatments in patients with CGD, so we propose the realization of a consensus by experts in order to establish guidelines for the treatment of mycobacterial disease in CGD.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 2","pages":"117-127"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39418887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

[Girl with hypersensitivity pneumonitis. A case report]. [女孩患有过敏性肺炎。[病例报告]。

Revista alergia Mexico Pub Date : 2021-01-01 DOI: 10.29262/ram.v68i1.844

David Loli-Ausejo, Francisca Vílchez-Sánchez, Margarita Tomás-Pérez

{"title":"[Girl with hypersensitivity pneumonitis. A case report].","authors":"David Loli-Ausejo, Francisca Vílchez-Sánchez, Margarita Tomás-Pérez","doi":"10.29262/ram.v68i1.844","DOIUrl":"https://doi.org/10.29262/ram.v68i1.844","url":null,"abstract":"Background: Hypersensitivity pneumonitis entails several inflammatory lung diseases that preferentially affect the alveolar and perialveolar tissue. It is a very rare disease in children, with a complicated diagnosis due to the fact that antigen exposure usually goes unnoticed.Case report: A 12-year-old girl with dry cough, dyspnea, wheezing, and tachypnea, with partial improvement after treatment with inhaled bronchodilators and corticoids. The spirometry showed a restrictive pattern and reduced lung diffusion capacity; in the CT scan, centrilobular ground-glass opacities were observed, and a lymphocyte count of CD4/CD8 of 2.46 (lymphocytosis) was obtained from the bronchoalveolar lavage. IgG positivity to bird feathers was obtained.Conclusions: The treatment of hypersensitivity pneumonitis is based on avoiding exposure to the causative agent, which is determined by the prognosis; for which taking an extensive medical history is of paramount importance. Corticosteroids can be prescribed based on the clinical response, the pulmonary function, and the radiological improvement.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 1","pages":"84-88"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39248062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Autoimmune diseases in patients with common variable immunodeficiency]. 【常见变异性免疫缺陷患者的自身免疫性疾病】。

Revista alergia Mexico Pub Date : 2021-01-01 DOI: 10.29262/ram.v68i1.894

Laura Berrón-Ruiz

{"title":"[Autoimmune diseases in patients with common variable immunodeficiency].","authors":"Laura Berrón-Ruiz","doi":"10.29262/ram.v68i1.894","DOIUrl":"https://doi.org/10.29262/ram.v68i1.894","url":null,"abstract":"Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency with an estimated prevalence of one in 10,000 to 50,000 inhabitants. This heterogeneous disease is characterized by decreased levels of serum immunoglobulins, a poor production of specific antibodies upon vaccination, and recurrent bacterial infections, particularly in the respiratory and gastrointestinal tract. A subgroup of patients is characterized by additional, and often predominant, manifestations of immune deregulation rather than pure immunodeficiency. Approximately, 30% of patients with CVID develop autoimmunity. Half of those complications can be attributed to autoimmune cytopenia, but also to other types of autoimmunity, such as organ-specific autoimmune diseases, often manifest as inflammatory disease, including inflammatory bowel disease, celiac disease, interstitial lung disease, some forms of arthritis, and vitiligo, among many others. New monogenic defects elucidate the immunopathological mechanism that causes the coincidence of immunodeficiency and autoimmunity. Autoimmune diseases have become the major clinical challenge in CVID, with new diagnostic tools, especially genetic ones, that improve the understanding of the different forms of immune deregulation.","PeriodicalId":21175,"journal":{"name":"Revista alergia Mexico","volume":"68 1","pages":"48-64"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39248057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0