Psychiatry Investigation最新文献_第5页

Prevalence and Medical Costs of Intellectual Disabilities and Pervasive Developmental Disorder in Korea: Based on National Health Insurance Service Claims Data from 2007 to 2019. 韩国智力残疾和广泛性发育障碍的患病率和医疗费用：基于2007年至2019年国民健康保险服务索赔数据

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-06-19 DOI: 10.30773/pi.2023.0123e

Beomjun Kim, In-Hwan Oh, Hyeon-Kyoung Cheong, Jun-Won Hwang

引用次数: 0

Changes in Heart Rate Variability in Adolescent Patients With Tic Disorders: A 1-Year Prospective Study. 青少年抽动障碍患者心率变异性的变化：1年前瞻性研究

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-07-10 DOI: 10.30773/pi.2025.0072

Hyeju Lee, Nahyung Lee, Yeje Lim, June Christoph Kang, Jeong-An Gim, Moon-Soo Lee

{"title":"Changes in Heart Rate Variability in Adolescent Patients With Tic Disorders: A 1-Year Prospective Study.","authors":"Hyeju Lee, Nahyung Lee, Yeje Lim, June Christoph Kang, Jeong-An Gim, Moon-Soo Lee","doi":"10.30773/pi.2025.0072","DOIUrl":"10.30773/pi.2025.0072","url":null,"abstract":"Objective: This longitudinal study examined the impact of tic disorders on autonomic nervous system function using heart rate variability (HRV) as a biomarker and assessed its association with quality of life over a 1-year period.Methods: The patient group comprised 39 individuals, of whom 19 were followed up after 1 year, whereas the control group included 30 individuals. Tic severity and quality of life were assessed using the Yale Global Tic Severity Scale and KIDSCREEN-27 questionnaire, respectively. HRV parameters were used to measure autonomic function during this period.Results: At baseline, patients with tic disorders demonstrated lower HRV, particularly in low-frequency (LF) power, and a higher standard deviation of the average normal-to-normal intervals, indicating significant autonomic dysregulation compared to control participants. Over the 1-year follow-up period, these patients demonstrated a decline in HRV indices, particularly LF power. HRV metrics and quality of life scores exhibited significant correlations at baseline, indicating that a better autonomic balance status was associated with perceived better quality of life. During follow-up, the correlations between HRV measures and psychological/behavioral scales observed at baseline were altered and no longer significant, potentially reflecting the effects of treatment and homeostatic adaptation over time.Conclusion: Tic disorders are associated with persistent autonomic dysfunction, which progressively impair physiological regulation and quality of life. The findings of this study elucidate the significance of incorporating strategies for autonomic modulation into treatment plans for patients with tic disorders.","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":" ","pages":"766-774"},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12301688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Graph Machine Learning With Systematic Hyper-Parameter Selection on Hidden Networks and Mental Health Conditions in the Middle-Aged and Old. 隐含网络上系统超参数选择的图机学习与中老年心理健康状况。

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-07-10 DOI: 10.30773/pi.2024.0249e

Kwang-Sig Lee, Byung-Joo Ham

引用次数: 0

Research on Haenyeo: Insights Into Human Adaptations to Extreme Environments. 海女研究：人类对极端环境的适应。

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-07-10 DOI: 10.30773/pi.2024.0394

Joon Hyuk Park, Ki Woong Kim

引用次数: 0

The Effect of Forkhead Box O1 Single Nucleotide Polymorphisms on Cortical Thickness and White Matter Integrity in High Suicide Risk Patients. 叉头盒O1单核苷酸多态性对高自杀风险患者皮质厚度和白质完整性的影响

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-07-10 DOI: 10.30773/pi.2024.0044e

Daun Shin, Youbin Kang, Aram Kim, Woo Suk Tae, Mi-Ryung Han, Kyu-Man Han, Byung-Joo Ham

引用次数: 0

Problematic Smartphone Use Is Associated With Current and Previous Major Depressive Disorder. 有问题的智能手机使用与当前和以前的重度抑郁症有关。

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-07-16 DOI: 10.30773/pi.2025.0011

Su Jeong Seong, Jin Pyo Hong, Bong-Jin Hahm, Sung Man Chang, Byung-Soo Kim, Dong-Woo Lee, Seong-Jin Cho, Jong-Ik Park, Jee Eun Park, Hong Jin Jeon

{"title":"Problematic Smartphone Use Is Associated With Current and Previous Major Depressive Disorder.","authors":"Su Jeong Seong, Jin Pyo Hong, Bong-Jin Hahm, Sung Man Chang, Byung-Soo Kim, Dong-Woo Lee, Seong-Jin Cho, Jong-Ik Park, Jee Eun Park, Hong Jin Jeon","doi":"10.30773/pi.2025.0011","DOIUrl":"10.30773/pi.2025.0011","url":null,"abstract":"Objective: Although many studies have demonstrated the association between depression and problematic smartphone use (PSU), temporal precedence of this relationship remains controversial. This study aimed to investigate the relationship between present PSU and both past and current major depressive disorder (MDD) among adults.Methods: We utilized data from the Korean Epidemiologic Catchment Area study, a nationwide epidemiologic survey that employed a multistage cluster sampling method. Participants were assessed using the Korean version of the Composite International Diagnostic Interview to diagnose MDD and the Smartphone Overuse Screening Questionnaire to identify PSU.Results: Of a total of 916 subjects, 139 (15.2%) belonged to the PSU group. The prevalence of PSU in older adults was substantial: 9.3% in the age group of 36-50 years and 5.4% in the age group of over 50 years. We found a significant association between MDD and PSU. Both current and previous MDD episodes were associated with an increased risk of PSU.Conclusion: This study confirmed the association of PSU and depression among general adult population and the precedence of MDD to PSU. Even previously resolved depression was found to affect current PSU.","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"22 7","pages":"813-820"},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12301686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Soyasaponin Bb Attenuates Morphine Withdrawal-Induced Anxiety-Like Behaviors in Male Mice by Rescuing GSK-3β/Nrf2 Signaling. 大豆皂苷Bb通过挽救GSK-3β/Nrf2信号通路减轻吗啡戒断诱导的雄性小鼠焦虑样行为。

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-07-16 DOI: 10.30773/pi.2025.0091

Jie Wu, Chenchen Zhu, Yin Shu, Yongli Lu, Lu Liu, Zhigang Xiao, Zicheng Li

{"title":"Soyasaponin Bb Attenuates Morphine Withdrawal-Induced Anxiety-Like Behaviors in Male Mice by Rescuing GSK-3β/Nrf2 Signaling.","authors":"Jie Wu, Chenchen Zhu, Yin Shu, Yongli Lu, Lu Liu, Zhigang Xiao, Zicheng Li","doi":"10.30773/pi.2025.0091","DOIUrl":"10.30773/pi.2025.0091","url":null,"abstract":"Objective: To examine the effect of Soyasaponin Bb on morphine withdrawal-induced anxiety-like behaviors in male mice and the corresponding mechanism.Methods: The chronic intermittent escalating-dose morphine administration paradigm and spontaneous withdrawal were used to induce anxiety-like behaviors in male mice. Open field test (OFT) and elevated plus maze test (EPM) were used to evaluate anxiety-like behaviors. Soyasaponin Bb was intragastrically administered. Western blot was used to monitor the level of GSK-3β, Nrf2, and superoxidase dismutase in the basolateral amygdala (BLA). Virus-mediated gene overexpression and knockdown were used to manipulate the expression of GSK-3β and Nrf2 in the BLA. Two-way analysis of variance followed by Tukey's test were used to make comparisons for the experiments between four groups. Student's t-test was used to make comparisons for the experiments between two groups.Results: Intragastric administration of Soyasaponin Bb attenuated morphine withdrawal-induced anxiety-like behaviors in male mice. Soyasaponin Bb rescued GSK-3β/Nrf2 signaling in the BLA in morphine withdrawn mice. Overexpression of GSK-3β in the BLA was sufficient to induce anxiety-like behaviors in male mice. Knockdown of GSK-3β in the BLA attenuated anxiety-like behaviors in male mice. Knockdown of Nrf2 in the BLA was sufficient to induce anxiety-like behaviors in male mice.Conclusion: Soyasaponin Bb could play anxiolytic effect by regulating GSK-3β/Nrf2 signaling and inhibition of GSK-3β in the BLA may represent a novel therapeutic approach to morphine addiction and anxiety disorders.","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"22 7","pages":"821-831"},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12301682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mediating Effect of Psychological Inflexibility, Insomnia, and Resilience on the Association Between Pain and Depression Among Patients With Chronic Pain. 心理不弹性、失眠和心理弹性在慢性疼痛患者疼痛与抑郁关系中的中介作用。

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-07-10 DOI: 10.30773/pi.2025.0065

Hussein Makhour, Seockhoon Chung

{"title":"Mediating Effect of Psychological Inflexibility, Insomnia, and Resilience on the Association Between Pain and Depression Among Patients With Chronic Pain.","authors":"Hussein Makhour, Seockhoon Chung","doi":"10.30773/pi.2025.0065","DOIUrl":"10.30773/pi.2025.0065","url":null,"abstract":"Objective: Chronic pain, impacting roughly 20% of the population, significantly affects quality of life and productivity. This study explored the mediating effects of psychological inflexibility, insomnia, and resilience on the association between pain and depression in patients with chronic pain.Methods: Data on demographics, pain characteristics, and psychological factors were obtained through an online survey involving 100 patients from the Asan Medical Center Pain Clinic. Measures included the Patient Health Questionnaire-9, Insomnia Severity Index (ISI), Acceptance and Action Questionnaire-II (AAQ-II), and Brief Resilience Scale (BRS). Statistical analyses involved correlation, linear regression, and mediation analyses.Results: A linear regression analysis revealed that the severity of depression was predicted by pain severity (β=0.18, p=0.018), ISI (β=0.22, p=0.010), AAQ-II (β=0.32, p<0.001), and BRS (β=-0.28, p=0.002). The mediation analysis showed that pain severity directly influenced depression severity. This relationship was partially mediated by ISI, AAQ-II, and BRS.Conclusion: This study underscores the necessity for holistic approaches in chronic pain management that address the mediating effect of psychological factors. Targeted interventions focusing on insomnia, psychological inflexibility, and resilience can significantly enhance mental health outcomes for patients with chronic pain.","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":" ","pages":"806-812"},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12301685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discriminative Accuracy of Affective Temperaments in Assessing Suicide Risk. 情感气质在评估自杀风险中的判别准确性。

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-07-01 Epub Date: 2025-07-16 DOI: 10.30773/pi.2025.0036

Kyeong A Kang, Suyeon Lee, Seong Yoon Kim, C Hyung Keun Park

{"title":"Discriminative Accuracy of Affective Temperaments in Assessing Suicide Risk.","authors":"Kyeong A Kang, Suyeon Lee, Seong Yoon Kim, C Hyung Keun Park","doi":"10.30773/pi.2025.0036","DOIUrl":"10.30773/pi.2025.0036","url":null,"abstract":"Objective: This study aimed to evaluate whether individual and composite scores of affective temperaments can differentiate high-risk suicide groups among patients with major depressive disorder (MDD) and to compare their discriminative accuracy.Methods: A retrospective review included 343 patients with MDD. Affective temperaments were assessed using the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire, while the Depressive Symptom Inventory-Suicidality Subscale was used to classify the high-risk suicide group. Receiver operating characteristic (ROC) curve analysis assessed the discriminative performance of five individual and three composite scores of affective temperaments, with area under the curve (AUC). Logistic regression analysis was conducted to examine whether depressive temperament and composite scores independently predicted suicide risk.Results: Depressive temperament demonstrated the highest discriminative accuracy among individual scores (AUC=0.754). All composite scores also showed good accuracy (AUC range=0.729-0.739). The results indicated that depressive temperament and three composite scores demonstrated good accuracy, with no significant differences between them. Additionally, irritable (AUC=0.660) and cyclothymic (AUC=0.650) temperaments exhibited sufficient accuracy. Logistic regression analysis indicated that only depressive temperament was a significant independent predictor of suicide risk.Conclusion: Depressive temperament and composite scores demonstrated good discriminative accuracy for identifying high-risk suicide groups in MDD. These findings highlight the importance of assessing affective temperaments as stable traits for evaluating and predicting suicide risk. Future longitudinal, multi-center studies are needed to further explore the role of affective temperaments in predicting suicide risk among patients with MDD.","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"22 7","pages":"796-805"},"PeriodicalIF":1.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12301687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychological Impact and Differences in Child and Adolescent Victims of Sexual Violence in South Korea: Using Data From a Sunflower Center in South Korea From 2015 to 2022. 韩国儿童和青少年性暴力受害者的心理影响和差异：使用韩国向日葵中心2015年至2022年的数据

IF 1.8 4区医学

Psychiatry Investigation Pub Date : 2025-06-01 Epub Date: 2025-06-16 DOI: 10.30773/pi.2024.0381

Minha Hong, Hyun-Soo Kim, Kyoung-Hoon Kim, Jiali Emily Koh, Changwoo Han, Seunghoon Lee, Jin Sun Ryu, Ah Rah Lee, Sang Min Lee

{"title":"Psychological Impact and Differences in Child and Adolescent Victims of Sexual Violence in South Korea: Using Data From a Sunflower Center in South Korea From 2015 to 2022.","authors":"Minha Hong, Hyun-Soo Kim, Kyoung-Hoon Kim, Jiali Emily Koh, Changwoo Han, Seunghoon Lee, Jin Sun Ryu, Ah Rah Lee, Sang Min Lee","doi":"10.30773/pi.2024.0381","DOIUrl":"10.30773/pi.2024.0381","url":null,"abstract":"Objective: Sexual violence against children and adolescents is a serious social problem. The characteristics of child and adolescent victims differ based on their varying developmental processes. Therefore, we conducted a comparative analysis to assess the same.Methods: Data were collected from victims of sexual violence between 2015 and 2022, from a Sunflower Center, which is a government-sponsored center for victims of sexual violence. The participants were classified into two groups: children under age 12 and adolescents over age 13 years. To compare and analyze data, we collected demographic information, information related to victimization events, and scores on the Children's Depression Inventory, Revised Children's Manifest Anxiety Scale, and Children's Revised Impact of Event Scale. A descriptive analysis, χ 2 test, Fisher's exact test, and multiple logistic regression analysis were performed.Results: Among 255 participants, 95 and 160 were children and adolescents, respectively. The percentage of forced molestation was significantly higher in children at 71.6% (n=68, p<0.001). Children included significantly more male participants (14.7%, n=14, p=0.007) than adolescents. Significant differences were observed between children and adolescents' depression, anxiety, and posttraumatic stress scores (p<0.001). Compared with children, adolescents demonstrated an adjusted odds ratio of 2.9 for high post-traumatic stress symptoms, 2.26 for high depressive symptoms, and 3.0 for high anxiety symptoms.Conclusion: We identified differences in the characteristics of sexual violence victims, particularly children and adolescents, and found that adolescent victims were more vulnerable to the psychological repercussions of abuse than child victims.","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"22 6","pages":"660-667"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0