Revista Argentina de microbiologia最新文献_第9页

Statin and aspirin use in parasitic infections as a potential therapeutic strategy: A narrative review 他汀类药物和阿司匹林作为一种潜在的治疗策略在寄生虫感染中的应用：叙述性综述。

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-07-01 DOI: 10.1016/j.ram.2023.01.006

Valentina Burgess , Juan D. Maya

{"title":"Statin and aspirin use in parasitic infections as a potential therapeutic strategy: A narrative review","authors":"Valentina Burgess , Juan D. Maya","doi":"10.1016/j.ram.2023.01.006","DOIUrl":"10.1016/j.ram.2023.01.006","url":null,"abstract":"<div>Infections, including zoonoses, constitute a threat to human health due to the spread of resistant pathogens. These diseases generate an inflammatory response controlled by a resolving mechanism involving specialized membrane lipid-derived molecules called lipoxins, resolvins, maresins, and protectins. The production of some of these molecules can be triggered by aspirin or statins. Thus, it is proposed that modulation of the host response could be a useful therapeutic strategy, contributing to the management of resistance to antiparasitic agents or preventing drift to chronic, host-damaging courses. Therefore, the present work presents the state of the art on the use of statins or aspirin for the experimental management of parasitic infections such as Chagas disease, leishmaniasis, toxoplasmosis or malaria. The methodology used was a narrative review covering original articles from the last seven years, 38 of which met the inclusion criteria. Based on the publications consulted, modulation of the resolution of inflammation using statins may be feasible as an adjuvant in the therapy of parasitic diseases. However, there was no strong experimental evidence on the use of aspirin; therefore, further studies are needed to evaluate its role inflammation resolution process in infectious diseases.</div>","PeriodicalId":21163,"journal":{"name":"Revista Argentina de microbiologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9245704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The rising threat of intrinsically resistant Candida species in Argentina 内在耐药念珠菌在阿根廷的威胁越来越大。

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-07-01 DOI: 10.1016/j.ram.2023.09.001

By Guillermo Garcia-Effron

引用次数: 0

Role of Proteus mirabilis flagella in biofilm formation 奇异变形杆菌鞭毛在生物膜形成中的作用。

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-07-01 DOI: 10.1016/j.ram.2023.01.005

Paola Scavone , Victoria Iribarnegaray , María José González , Nicolás Navarro , Nicole Caneles-Huerta , Jorge Jara-Wilde , Steffen Härtel , Pablo Zunino

{"title":"Role of Proteus mirabilis flagella in biofilm formation","authors":"Paola Scavone , Victoria Iribarnegaray , María José González , Nicolás Navarro , Nicole Caneles-Huerta , Jorge Jara-Wilde , Steffen Härtel , Pablo Zunino","doi":"10.1016/j.ram.2023.01.005","DOIUrl":"10.1016/j.ram.2023.01.005","url":null,"abstract":"<div>Proteus mirabilis (P. mirabilis) is a common etiological agent of urinary tract infections, particularly those associated with catheterization. P. mirabilis efficiently forms biofilms on different surfaces and shows a multicellular behavior called ‘swarming’, mediated by flagella. To date, the role of flagella in P. mirabilis biofilm formation has been under debate. In this study, we assessed the role of P. mirabilis flagella in biofilm formation using an isogenic allelic replacement mutant unable to express flagellin. Different approaches were used, such as the evaluation of cell surface hydrophobicity, bacterial motility and migration across catheter sections, measurements of biofilm biomass and biofilm dynamics by immunofluorescence and confocal microscopy in static and flow models. Our findings indicate that P. mirabilis flagella play a role in biofilm formation, although their lack does not completely avoid biofilm generation. Our data suggest that impairment of flagellar function can contribute to biofilm prevention in the context of strategies focused on particular bacterial targets.</div>","PeriodicalId":21163,"journal":{"name":"Revista Argentina de microbiologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9772786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Microbiological and chemical characterization of water kefir: An innovative source of potential probiotics for bee nutrition 水开菲尔的微生物学和化学特性:一种潜在的蜜蜂营养益生菌的创新来源

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-04-01 DOI: 10.1016/j.ram.2022.09.003

María A. Rodríguez , Leticia A. Fernández , Marina L. Díaz , Mónica Pérez , Miguel Corona , Francisco J. Reynaldi

{"title":"Microbiological and chemical characterization of water kefir: An innovative source of potential probiotics for bee nutrition","authors":"María A. Rodríguez , Leticia A. Fernández , Marina L. Díaz , Mónica Pérez , Miguel Corona , Francisco J. Reynaldi","doi":"10.1016/j.ram.2022.09.003","DOIUrl":"10.1016/j.ram.2022.09.003","url":null,"abstract":"<div>We evaluated the microbial composition of water kefir grains and beverage over the course of one year to determine whether the number and type of microorganisms changed over the time. Bacteria and yeast colonies with different morphologies were isolated from water kefir and their antimicrobial activity was evaluated against Paenibacillus larvae and Ascosphaera apis. A chemical characterization of kefir was also carried out. Our results confirmed that bacteria and yeasts were more numerous in kefir grains compared with those in the beverage. The counts of microorganisms declined, although an important microbial community was still present in kefir after the long storage period. Eleven strains which inhibited bee pathogens were isolated from kefir. Genotypic results demonstrated that these isolates included Lentilactobacillus hilgardii, Lentilactobacillus buchneri and Saccharomyces cerevisiae. Thus, water kefir may be an innovative source of potential probiotic strains for bee nutrition in order to control honeybee diseases.</div>","PeriodicalId":21163,"journal":{"name":"Revista Argentina de microbiologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9701259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Laboratory surveillance of invasive Haemophilus influenzae disease in Argentina, 2011–2019 2011-2019年阿根廷侵袭性流感嗜血杆菌病实验室监测

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-04-01 DOI: 10.1016/j.ram.2022.08.002

Adriana Efron , Daniela Nápoli , Silvina Neyro , María del Valle Juárez , María Moscoloni , Nahuel Sánchez Eluchans , Mabel Regueira , Silvina Lavayén , Argentinean H. influenzae Working Group , Diego Faccone , Mauricio Santos

{"title":"Laboratory surveillance of invasive Haemophilus influenzae disease in Argentina, 2011–2019","authors":"Adriana Efron , Daniela Nápoli , Silvina Neyro , María del Valle Juárez , María Moscoloni , Nahuel Sánchez Eluchans , Mabel Regueira , Silvina Lavayén , Argentinean H. influenzae Working Group , Diego Faccone , Mauricio Santos","doi":"10.1016/j.ram.2022.08.002","DOIUrl":"10.1016/j.ram.2022.08.002","url":null,"abstract":"<div>The incorporation of Haemophilus influenzae type b (Hib) vaccine into the Argentine National Immunization Program in 1998 resulted in a dramatic decrease in the incidence of invasive disease due to this serotype. We assessed 1405 H. influenzae (Hi) isolates causing invasive infections referred to the National Reference Laboratory between 2011 and 2019. Non-encapsulated Hi were the most common strains (44.5%), followed by types b (41.1%) and a (10.0%). Significant increase in the proportion of type b was observed, from 31.2% in 2011, to 50% in 2015, correlating with the peak incidence rate, later decreasing to 33.6% by 2019. We compared the genetic relationship between clones circulating during the period of increased Hib incidence (2011–2015) and those of the prevaccination-transition period (1997–1998). Four pulsotypes predominated in both periods, G, M, P and K, G being the most common. Multi-locus sequence typing revealed that the 4 pulsotypes belonged to ST6, or one of its simple or double locus variants. Isolates from fully vaccinated individuals did not differ from those of the rest of the population studied. After ruling out aspects associated with emergence of specific clones, we concluded that factors such as low booster coverage rates, delayed vaccination schedules and use of different vaccines may have contributed to the reemergence of Hib infections.</div>","PeriodicalId":21163,"journal":{"name":"Revista Argentina de microbiologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10020057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Comprehensive evaluation of abattoirs with no Hazard Analysis Critical Control Point plan in Tucumán, Argentina 阿根廷Tucumán没有危害分析关键控制点计划的屠宰场的综合评价

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-04-01 DOI: 10.1016/j.ram.2022.11.003

Gabriela Pérez Terrazzino , Magdalena Costa , Alejandro López Campo , Carolina Saade , María Paula Moreno Mochi , Marcelo Signorini , Ariel Roge , Claudia Van Der Ploeg , Gerardo Leotta , María Ángela Jure

{"title":"Comprehensive evaluation of abattoirs with no Hazard Analysis Critical Control Point plan in Tucumán, Argentina","authors":"Gabriela Pérez Terrazzino , Magdalena Costa , Alejandro López Campo , Carolina Saade , María Paula Moreno Mochi , Marcelo Signorini , Ariel Roge , Claudia Van Der Ploeg , Gerardo Leotta , María Ángela Jure","doi":"10.1016/j.ram.2022.11.003","DOIUrl":"10.1016/j.ram.2022.11.003","url":null,"abstract":"<div>This work focused on the comprehensive study of two provincial transit abattoirs in Tucumán, Argentina, with no Hazard Analysis Critical Control Point (HACCP) plan. Visits (n=20) were conducted between 2016 and 2018 during the operational and post-operational processes. Risk was estimated and the bacteriological analysis of carcass and environmental samples was performed. Risk estimation showed the predominance of high risk in both abattoirs. The main deviations from the HACCP plan were: deficient building conditions, deficient workflow, lack of sectorization of changing rooms and bathrooms, lack of implementation of Standardized Sanitary Operational Procedures, and no food safety training of workers. The counts of indicator microorganisms from both abattoirs were not significant. Salmonella spp. was isolated from 7.5% carcass and 7.3% environmental samples. The Salmonella serovars identified were Cerro, Corvallis, Havana and Agona. Shiga toxin (stx) genes were detected in 24.4% carcass and 30.9% environmental samples. The isolates were characterized as Escherichia coli O8:H7/stx1, O116:H49/stx2 and O136:H40/stx2. Based on these results, it would be possible to implement an improvement plan in Tucumán abattoirs together with the local health authorities. Still, the need to work jointly with the sanitary authority in search of a unique sanitary standard for Argentina remains unaddressed.</div>","PeriodicalId":21163,"journal":{"name":"Revista Argentina de microbiologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of a Clostridioides difficile ST-293 isolate from a recurrent infection in Argentina 阿根廷一次复发性感染难辨梭菌ST-293分离株的鉴定

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-04-01 DOI: 10.1016/j.ram.2022.09.004

P. Cecilia Soldavini Pelichotti , Daniela Cejas , Liliana Fernández-Caniggia , Fernando M. Trejo , Pablo F. Pérez

{"title":"Characterization of a Clostridioides difficile ST-293 isolate from a recurrent infection in Argentina","authors":"P. Cecilia Soldavini Pelichotti , Daniela Cejas , Liliana Fernández-Caniggia , Fernando M. Trejo , Pablo F. Pérez","doi":"10.1016/j.ram.2022.09.004","DOIUrl":"10.1016/j.ram.2022.09.004","url":null,"abstract":"<div>Clostridioides difficile is an opportunistic spore-forming pathogen responsible for antibiotic-associated diarrhea in humans. C. difficile produces two main toxins: TcdA and TcdB as well as a third toxin named binary toxin (CDT) that is also involved in virulence. The present study aimed at characterizing the C. difficile isolate ALCD3 involved in a relapse episode of nosocomial infection. Molecular characterization showed that isolate ALCD3 belongs to toxinotype 0/v and the MLST analysis demonstrated allelic profile adk:91, atpA:1, dxr:2, glyA: 1, recA:27, sodA: 1 and tpi:1 which corresponds to ST293 (MLST clade: 1). During growth, isolate ALCD3 showed an early increase in the sporulation ratio as well as maximal values of heat resistant forms after 2 days of incubation. Both sporulation kinetics and production of heat resistant forms were faster for isolate ALCD3 than for the reference strain VPI 10463. Germination in the presence of the natural germinant taurocholate was faster for isolate ALCD3 than for strain VPI 10463, which indicates that isolate ALCD3 starts cortex hydrolysis earlier than strain VPI 10463. Furthermore, the co-germinant glycine, induces rapid release of dipicolinic acid (DPA) in isolate ALCD3. These findings indicate that isolate ALCD3 is particularly efficient in both sporulation and germination. The present work represents the first report of the circulation of C. difficile ST293 in Argentina. The ability of isolate ALCD3 to produce toxins and its high sporulation/germination capacity are key features compatible with a microorganism with high dissemination potential and the possibility of inducing recurrent infections.</div>","PeriodicalId":21163,"journal":{"name":"Revista Argentina de microbiologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9647819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification and molecular characterization of Orf virus infection in occupationally exposed women in South America 南美职业暴露妇女口蹄疫病毒感染的鉴定和分子特征

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-04-01 DOI: 10.1016/j.ram.2022.07.002

Andrea Peralta , Carlos Flores-Olivares , Andrea Verna , Erika González-Altamiranda , Ernesto Odriozola , Carolina Madariaga , Anselmo Odeón , Guido A. König , Germán Cantón

引用次数: 0

El papel central de la secuenciación masiva y la correcta identificación de microorganismos en el desarrollo de bioinsumos agrícolas seguros 大规模测序和微生物正确鉴定在安全农业生物投入开发中的中心作用

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-04-01 DOI: 10.1016/j.ram.2023.05.001

Diego Herman Sauka

引用次数: 0

Effect of glyphosate and ciprofloxacin exposure on enteric bacteria of tadpoles 草甘膦和环丙沙星暴露对蝌蚪肠道细菌的影响

IF 1.9 4区生物学

Revista Argentina de microbiologia Pub Date : 2023-04-01 DOI: 10.1016/j.ram.2022.08.004

Ana P. Cuzziol Boccioni , Guillermo García-Effron , Paola M. Peltzer , Rafael C. Lajmanovich

{"title":"Effect of glyphosate and ciprofloxacin exposure on enteric bacteria of tadpoles","authors":"Ana P. Cuzziol Boccioni , Guillermo García-Effron , Paola M. Peltzer , Rafael C. Lajmanovich","doi":"10.1016/j.ram.2022.08.004","DOIUrl":"10.1016/j.ram.2022.08.004","url":null,"abstract":"<div>The high load of agrochemicals and antibiotics present in agricultural aquatic environments represents a risk for wildlife. Since enteric bacteria, which play a key role in the physiological functioning of their hosts, are sensitive to a wide variety of pollutants, their study allows to evaluate the health of organisms. This study aimed to evaluate the effects of commercial formulations of a glyphosate-based herbicide (GBH) and the antibiotic ciprofloxacin (CIP), individually and in mixture, on the bacterial diversity of the intestinal content of common toad (Rhinella arenarum) tadpoles. The diversity of cultivable fast-growing bacteria with low nutritional requirements was evaluated using classic microbiological tests and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry identification. Bacterial diversity varied among treatments. Taxa diversity increased in the GBH-treated group but decreased in the CIP-treated group. Remarkably, Yersinia spp. and Proteus spp. were only found in the GBH-treated group. The prevalence of Klebsiella spp. and Pseudomonas spp. decreased in the intestinal microbiota of the GBH-CIP-treated group. To our knowledge, this is the first report on the alteration of cultivable enteric bacteria of autochthonous tadpoles due to two pollutants of emerging concern. Our results demonstrate that R. arenarum tadpoles can be used as non-conventional model organisms for environmental pollution monitoring. Our preliminary findings would contribute to understanding how the presence of GBH and CIP in freshwaters may represent a threat to wildlife and human health by causing enteric dysbiosis of part of the bacterial community.</div>","PeriodicalId":21163,"journal":{"name":"Revista Argentina de microbiologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9645397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2