Respirology最新文献_第9页

Treatable traits-Where we are, where we are headed. 可治疗特质--我们的现状和未来。

IF 6.9 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-05-28 DOI: 10.1111/resp.14758

Vanessa Marie McDonald, Peter Gerard Gibson

引用次数: 0

Protecting children from tobacco industry interference. 保护儿童免受烟草业的干扰。

IF 6.6 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-05-15 DOI: 10.1111/resp.14750

Matthew Peters, Moya Vandeleur

引用次数: 0

Lung ultrasound is a promising screening tool to rule out interstitial lung disease in patients with rheumatoid arthritis. 肺部超声波是一种很有前途的筛查工具，可用于排除类风湿关节炎患者的间质性肺病。

IF 6.9 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-02-18 DOI: 10.1111/resp.14679

M Otaola, F Paulin, M Rosemffet, J Balcazar, M Perandones, P Orausclio, T Cazenave, S Rossi, S Marciano, E Schneeberger, G Citera

{"title":"Lung ultrasound is a promising screening tool to rule out interstitial lung disease in patients with rheumatoid arthritis.","authors":"M Otaola, F Paulin, M Rosemffet, J Balcazar, M Perandones, P Orausclio, T Cazenave, S Rossi, S Marciano, E Schneeberger, G Citera","doi":"10.1111/resp.14679","DOIUrl":"10.1111/resp.14679","url":null,"abstract":"Background and objective: It is still controversial how to screen for interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA). We aimed to evaluate the performance of lung ultrasound (LUS) as a screening tool for RA-ILD and to compare it with the performance of chest auscultation, chest x-ray and pulmonary function tests (PFTs).Methods: Cross-sectional study of consecutive RA patients evaluated at a Rheumatology Clinic in Buenos Aires between January and December 2022. High-resolution computed tomography (HRCT) was the gold standard for diagnosing ILD and was performed within 30 days of the LUS, chest x-ray and PFTs. Investigators were blinded to HRCT results and patients' clinical data. LUS was performed by exploring 14 areas and was considered positive when the sum of B lines was ≥5. Performance for the diagnosis of ILD was reported for each diagnostic test.Results: One hundred and six patients were included; 87 (82%) were women. Median age was 60.9 (±9.5) years-old. A total of 32 (30.2%, 95% CI: 21.6%-39.9%) had ILD. The sensitivity and negative predictive value of LUS were 90.6% (95% CI 75.0%-98.0%) and 94.7% (95% CI 85.4%-98.9%), respectively. LUS performance was superior to that of the other evaluated diagnostic tests for screening ILD.Conclusions: Given that the US is a low-cost point-of-care tool with a high negative predictive value, it is emerging as a valuable tool for ruling out ILD in patients with RA.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":null,"pages":null},"PeriodicalIF":6.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139900370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contemporary Concise Review 2023: Environmental and occupational lung diseases. 2023 年当代简明评论》：环境和职业肺病。

IF 6.6 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-06-03 DOI: 10.1111/resp.14761

Kazuhiro Yatera, Chinatsu Nishida

引用次数: 0

Treatable traits in pre-COPD: Time to extend the treatable traits paradigm beyond established disease. 慢性阻塞性肺病前期的可治疗性状：是时候将可治疗性状范式扩展到已确诊疾病之外了。

IF 6.6 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-06-11 DOI: 10.1111/resp.14760

Shyamali C Dharmage, Rosa Faner, Alvar Agustí

{"title":"Treatable traits in pre-COPD: Time to extend the treatable traits paradigm beyond established disease.","authors":"Shyamali C Dharmage, Rosa Faner, Alvar Agustí","doi":"10.1111/resp.14760","DOIUrl":"10.1111/resp.14760","url":null,"abstract":"To date, the treatable traits (TTs) approach has been applied in the context of managing diagnosed diseases. TTs are clinical characteristics and risk factors that can be identified clinically and/or biologically, and that merit treatment if present. There has been an exponential increase in the uptake of this approach by both researchers and clinicians. Realizing the potential of the TTs approach to pre-clinical disease, this expert review proposes that it is timely to consider acting on TTs present before a clinical diagnosis is made, which might help to prevent development of the full disease. Such an approach is ideal for diseases where there is a long pre-clinical phase, such as in chronic obstructive pulmonary disease (COPD). The term 'pre-COPD' has been recently proposed to identify patients with respiratory symptoms and/or structural or functional abnormalities without airflow limitation. They may eventually develop airflow limitation with time but patients with pre-COPD are likely to have traits that are already treatable. This review first outlines the contribution of recently generated knowledge into lifetime lung function trajectories and the conceptual framework of 'GETomics' to the field of pre-COPD. GETomics is a dynamic and cumulative model of interactions between genes and the environment throughout the lifetime that integrates information from multi-omics to understand aetiology and mechanisms of diseases. This review then discusses the current evidence on potential TTs in pre-COPD patients and makes recommendations for practice and future research. At a broader level, this review proposes that introducing the TTs in pre-COPD may help reenergize the preventive approaches to health and diseases.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":null,"pages":null},"PeriodicalIF":6.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141306741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Connecting the dots: Tracing the tuberculosis-diabetes link across time. 连接点：追踪结核病与糖尿病之间的时空联系。

IF 6.9 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-05-08 DOI: 10.1111/resp.14736

Simone E Barry

引用次数: 0

Evaluating artificial intelligence responses to respiratory medicine questions. 评估人工智能对呼吸内科问题的回答。

IF 6.9 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-05-10 DOI: 10.1111/resp.14733

Hong Luo, Jisong Yan, Xia Zhou

引用次数: 0

Effect of complicated, untreated and uncontrolled diabetes and pre-diabetes on treatment outcome among patients with pulmonary tuberculosis. 复杂、未治疗和未控制的糖尿病及糖尿病前期对肺结核患者治疗效果的影响。

IF 6.6 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-03-27 DOI: 10.1111/resp.14714

Kyung Hoon Kim, Hyung Woo Kim, Yong Hyun Kim, Yeonhee Park, Sung Soo Jung, Jin Woo Kim, Jee Youn Oh, Heayon Lee, Sung Kyoung Kim, Sun-Hyung Kim, Jiwon Lyu, Yousang Ko, Sun Jung Kwon, Yun-Jeong Jeong, Do Jin Kim, Hyeon-Kyoung Koo, Yangjin Jegal, Sun Young Kyung, Sung Soon Lee, Jae Seuk Park, Ju Sang Kim, Jinsoo Min

{"title":"Effect of complicated, untreated and uncontrolled diabetes and pre-diabetes on treatment outcome among patients with pulmonary tuberculosis.","authors":"Kyung Hoon Kim, Hyung Woo Kim, Yong Hyun Kim, Yeonhee Park, Sung Soo Jung, Jin Woo Kim, Jee Youn Oh, Heayon Lee, Sung Kyoung Kim, Sun-Hyung Kim, Jiwon Lyu, Yousang Ko, Sun Jung Kwon, Yun-Jeong Jeong, Do Jin Kim, Hyeon-Kyoung Koo, Yangjin Jegal, Sun Young Kyung, Sung Soon Lee, Jae Seuk Park, Ju Sang Kim, Jinsoo Min","doi":"10.1111/resp.14714","DOIUrl":"10.1111/resp.14714","url":null,"abstract":"Background and objective: Patients with tuberculosis and diabetes have a higher risk of unfavourable anti-tuberculosis treatment outcomes. In the present study, we aimed to evaluate the effects of various diabetes statuses on the outcomes of patients with pulmonary tuberculosis.Methods: Among the patients with pulmonary tuberculosis enrolled in the Korea Tuberculosis Cohort (KTBC) registry and the multicentre prospective cohort study of pulmonary tuberculosis (COSMOTB), those with diabetes and complicated diabetes were identified. The primary and secondary outcomes were unfavourable outcomes and mortality, respectively. The effect of diabetes and complicated diabetes on the outcomes was assessed using multivariable logistic regression analysis. Using COSMOTB, subgroup analyses were performed to assess the association between various diabetes statuses and outcomes.Results: In the KTBC, diabetes (adjusted odds ratio [aOR] = 1.93, 95% CI = 1.64-2.26) and complicated diabetes (aOR = 1.96, 95% CI = 1.67-2.30) were significantly associated with unfavourable outcomes, consistent with the COSMOTB data analysis. Based on subgroup analysis, untreated diabetes at baseline was an independent risk factor for unfavourable outcomes (aOR = 2.72, 95% CI = 1.26-5.61). Prediabetes and uncontrolled diabetes increased unfavourable outcomes and mortality without statistical significance.Conclusion: Untreated and complicated diabetes at the time of tuberculosis diagnosis increases the risk of unfavourable outcomes and mortality.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":null,"pages":null},"PeriodicalIF":6.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140306726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

VCD/ILO: Seeing and believing. VCD/ILO：眼见为实。

IF 6.9 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-05-06 DOI: 10.1111/resp.14735

Philip Bardin

引用次数: 0

Rethinking the need for increased clinical and radiological awareness of incidentally discovered interstitial lung abnormalities on CT chest. 重新思考是否需要提高临床和放射学对胸部 CT 偶然发现的肺间质异常的认识。

IF 6.9 2区医学

Respirology Pub Date : 2024-07-01 Epub Date: 2024-05-28 DOI: 10.1111/resp.14757

Stefano Palmucci, Linda Reali, Gianluca Sambataro, Antonio Basile, Carlo Vancheri

引用次数: 0