Respirology最新文献_第5页

Contemporary Concise Review 2023: Interstitial lung disease. 2023 年当代简明评论》：间质性肺病

IF 6.6 2区医学

Respirology Pub Date : 2024-12-01 Epub Date: 2024-10-22 DOI: 10.1111/resp.14848

Yuben Moodley

引用次数: 0

Prologue: Leading women in respiratory clinical sciences. 序言：呼吸临床科学领域的领军女性。

IF 5.3 2区医学

Respirology Pub Date : 2024-12-01 Epub Date: 2024-10-24 DOI: 10.1111/resp.14841

Anne-Marie Russell, Kathleen O Lindell

引用次数: 0

Letter from the UK: Developing the ecosystem for career advancement of women. 英国来信：发展促进妇女职业发展的生态系统。

IF 5.3 2区医学

Respirology Pub Date : 2024-12-01 Epub Date: 2024-10-24 DOI: 10.1111/resp.14842

Anne-Marie Russell

引用次数: 0

Ventilation heterogeneity is increased in adults exposed to coal mine fire-related PM_2.5. 暴露于煤矿火灾相关 PM2.5 的成年人通风异质性增加。

IF 5.3 2区医学

Respirology Pub Date : 2024-12-01 Epub Date: 2024-08-19 DOI: 10.1111/resp.14817

Thomas McCrabb, Brigitte Borg, Caroline X Gao, Catherine Smith, Claire F O'Sullivan, David Brown, Jillian Ikin, Annie Makar, Tyler Lane, Michael J Abramson, Bruce R Thompson

{"title":"Ventilation heterogeneity is increased in adults exposed to coal mine fire-related PM2.5.","authors":"Thomas McCrabb, Brigitte Borg, Caroline X Gao, Catherine Smith, Claire F O'Sullivan, David Brown, Jillian Ikin, Annie Makar, Tyler Lane, Michael J Abramson, Bruce R Thompson","doi":"10.1111/resp.14817","DOIUrl":"10.1111/resp.14817","url":null,"abstract":"Background and objectives: The Hazelwood Health Study was set up to study long-term health effects of a mine fire that blanketed residents of the Latrobe Valley with smoke for 45 days in 2014. The Respiratory Stream specifically assessed the impact of fine particulate matter <2.5 μm diameter (PM2.5) exposure from mine fire smoke on lung health. The multiple breath nitrogen washout (MBW) test assesses ventilation heterogeneity, which may detect sub-clinical airways dysfunction not identified using standard tests such as spirometry. This analysis assessed the association of PM2.5 exposure with measures of ventilation heterogeneity.Methods: Exposed (Morwell) and unexposed (Sale) participants were recruited 3.5-4 years after the fire from those who had participated in an Adult Survey. MBW was performed to measure lung clearance index (LCI), functional residual capacity (FRC), acinar (Sacin) and conductive (Scond) ventilation heterogeneity. PM2.5 exposure was estimated with emission and chemical transport models. Multivariable linear regression models were fitted controlling for confounders.Results: We recruited 519 participants. MBW tests were conducted on 504 participants with 479 acceptable test results (40% male; 313 exposed, 166 unexposed). Exposure to mine fire-related PM2.5 was associated with increasing Scond (β = 1.57/kL, 95%CI: 0.20-2.95, p = 0.025), which was comparable to the estimated effect on Scond of 4.7 years of aging. No other MBW outcomes were statistically different.Conclusion: Increasing exposure to PM2.5 was associated with increased ventilation heterogeneity in the conductive region of the lungs 4 years after the event.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":"1058-1066"},"PeriodicalIF":5.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Environmental impact of inhaled medicines: A Thoracic Society of Australia and New Zealand position statement. 吸入药物对环境的影响：澳大利亚和新西兰胸腔协会立场声明。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-13 DOI: 10.1111/resp.14852

Danielle F Wurzel, Brett D Montgomery, Natalie Anderson, Elena K Schneider-Futschik, Johnson George, Sinthia Bosnic-Anticevich, Emily Stone, Robert J Hancox, James Fingleton, Stephanie Kuek, Helen Tope, John Blakey

{"title":"Environmental impact of inhaled medicines: A Thoracic Society of Australia and New Zealand position statement.","authors":"Danielle F Wurzel, Brett D Montgomery, Natalie Anderson, Elena K Schneider-Futschik, Johnson George, Sinthia Bosnic-Anticevich, Emily Stone, Robert J Hancox, James Fingleton, Stephanie Kuek, Helen Tope, John Blakey","doi":"10.1111/resp.14852","DOIUrl":"https://doi.org/10.1111/resp.14852","url":null,"abstract":"Globally, more than 1.2 billion inhalers are purchased for asthma and chronic obstructive pulmonary disease (COPD) annually. In Australia and New Zealand, pressurized metered dose inhalers (pMDIs) are the leading delivery device prescribed and pMDI salbutamol can be purchased over the counter in Australia. These inhalers are a major contributor to healthcare related greenhouse gases. This is due to the propellants that they currently contain which have extremely high global warming potential (GWP). In this position paper, we report the findings of a Thoracic Society of Australia and New Zealand (TSANZ) working group on the environmental impact of inhaled respiratory medicines. We reviewed the use of inhaled medicines in Australia and New Zealand and their contribution to climate change and other environmental degradation. We propose strategies for health professionals and consumers to reduce environmental impact in the management of airway diseases. These include accurate diagnosis to avoid unnecessary treatment, better disease control to minimize the need for reliever therapy and actively choosing inhaler devices with lower environmental impacts when clinically appropriate. Inhaler selection should be tailored to the individual, aiming to achieve the best possible clinical outcome. Choosing an appropriate inhaler for an individual involves consideration of factors such as dexterity, inspiratory capacity and cost. In our current climate emergency and with the availability of lower carbon alternatives, health professionals should also consider environmental impact.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A 5-year perspective on coronavirus diseases 2019 (COVID-19). 冠状病毒疾病 5 年展望 2019（COVID-19）。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-09-03 DOI: 10.1111/resp.14826

David S C Hui, Alimuddin Zumla

引用次数: 0

DUETS for Light's in separating exudate from transudate. DUETS 用于分离渗出液和渗出液。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-07-03 DOI: 10.1111/resp.14780

Astrid Gardiner, Ryan Ling, Yiong-Huak Chan, Jose Porcel, Y C Gary Lee, Chia-Meng Teoh, Mei-Fong Liew, Jeevesh Kapur, Seow-Ping Low, Pyng Lee

{"title":"DUETS for Light's in separating exudate from transudate.","authors":"Astrid Gardiner, Ryan Ling, Yiong-Huak Chan, Jose Porcel, Y C Gary Lee, Chia-Meng Teoh, Mei-Fong Liew, Jeevesh Kapur, Seow-Ping Low, Pyng Lee","doi":"10.1111/resp.14780","DOIUrl":"10.1111/resp.14780","url":null,"abstract":"Background: Fifty years since its inception, Light's criteria have aided in classifying pleural effusions (PEs) as exudates if 1 or more criteria are met. Thoracic ultrasound (US) emerges as a non-invasive technique for point of care use especially if pleural procedures are contemplated.Objective: We aimed to develop a score based on radiological and US features that could separate exudates from transudates without serum and pleural fluid biochemical tests necessary for Light's criteria.Methods: A prospective review of consecutive patients with PE who underwent thoracocentesis was performed. CXRs were evaluated for laterality followed by US for echogenicity, pleural nodularity, thickening and septations. PE was classified as exudate or transudate according to Light's criteria and corroborated with albumin gradient. A score combining radiological and US features was developed.Results: We recruited 201 patients with PE requiring thoracocentesis. Mean age was 64 years, 51% were females, 164 (81.6%) were exudates, and 37 (18.4%) were transudates. Assigning 1-point for Diaphragmatic nodularity, Unilateral, Echogenicity, Pleural Thickening and Septations, DUETS ranged from 1 to 5. DUETS ≥2 indicated high likelihood for exudate (PPV 98.8%, NPV 100%) with 1% misclassification versus 6.9% using Light's criteria (p < 0.001).Conclusion: DUETS separated exudates from transudates with good accuracy, and could obviate paired serum and pleural fluid tests necessary for Light's criteria computation. Our study reflected real world practice where DUETS performed better than Light's criteria for PE that arose from more than one disease processes, and in the evaluation of patients with PE who have received diuretics.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":"976-984"},"PeriodicalIF":6.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From light to sound: Ultrasound outshines Light's criteria for pleural effusions classification. 从光到声：超声波优于 Light 的胸腔积液分类标准。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-08-28 DOI: 10.1111/resp.14825

Arash Badiei

引用次数: 0

Computed tomography mucus plugs and airway tree structure in patients with chronic obstructive pulmonary disease: Associations with airflow limitation, health-related independence and mortality. 慢性阻塞性肺病患者的计算机断层扫描粘液栓和气道树结构：与气流受限、健康相关独立性和死亡率的关系。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-06-24 DOI: 10.1111/resp.14776

Naoya Tanabe, Kaoruko Shimizu, Hiroshi Shima, Nobuyasu Wakazono, Yusuke Shiraishi, Kunihiko Terada, Satoru Terada, Tsuyoshi Oguma, Ryo Sakamoto, Masaru Suzuki, Hironi Makita, Atsuyasu Sato, Susumu Sato, Masaharu Nishimura, Satoshi Konno, Toyohiro Hirai

{"title":"Computed tomography mucus plugs and airway tree structure in patients with chronic obstructive pulmonary disease: Associations with airflow limitation, health-related independence and mortality.","authors":"Naoya Tanabe, Kaoruko Shimizu, Hiroshi Shima, Nobuyasu Wakazono, Yusuke Shiraishi, Kunihiko Terada, Satoru Terada, Tsuyoshi Oguma, Ryo Sakamoto, Masaru Suzuki, Hironi Makita, Atsuyasu Sato, Susumu Sato, Masaharu Nishimura, Satoshi Konno, Toyohiro Hirai","doi":"10.1111/resp.14776","DOIUrl":"10.1111/resp.14776","url":null,"abstract":"Background and objective: Mucus plugs and underlying airway tree structure can affect airflow limitation and prognosis in patients with chronic obstructive pulmonary disease (COPD), but their relative roles are unclear. This study used two COPD cohorts to examine whether mucus plugs on computed tomography (CT) were associated with airflow limitation and clinical outcomes independent of other airway structural changes and emphysema.Methods: Based on visual CT assessment, patients with mucus plugs in 0, 1-2 and ≥3 lung segments were assigned to no-, low- and high-mucus groups. Loss of health-related independence and mortality were prospectively recorded for 3 and 10 years in the Kyoto-Himeji and Hokkaido cohorts, respectively. The percentages of the wall area of the central airways (WA%), total airway count (TAC) and emphysema were quantified on CT.Results: Of 199 and 96 patients in the Kyoto-Himeji and Hokkaido cohorts, 34% and 30%, respectively, had high mucus scores. In both cohorts, TAC was lower in the high-mucus group than in the no-mucus group, whereas their emphysema severity did not differ. High mucus score and low TAC were independently associated with airflow limitation after adjustment for WA% and emphysema. In multivariable models adjusted for WA% and emphysema, TAC, rather than mucus score, was associated with a greater rate of loss of independence, whereas high mucus score, rather than TAC, was associated with increased mortality.Conclusion: Mucus plugs and lower airway branch count on CT had distinct roles in airflow limitation, health-related independence and mortality in patients with COPD.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":"951-961"},"PeriodicalIF":6.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Picture this: The future of imaging biomarkers in COPD. 想象一下：慢性阻塞性肺病成像生物标志物的未来。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-08-01 DOI: 10.1111/resp.14808

Cara Flynn, Chris Brightling

引用次数: 0