Respirology最新文献_第3页

DUETS for Light's in separating exudate from transudate. DUETS 用于分离渗出液和渗出液。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-07-03 DOI: 10.1111/resp.14780

Astrid Gardiner, Ryan Ling, Yiong-Huak Chan, Jose Porcel, Y C Gary Lee, Chia-Meng Teoh, Mei-Fong Liew, Jeevesh Kapur, Seow-Ping Low, Pyng Lee

{"title":"DUETS for Light's in separating exudate from transudate.","authors":"Astrid Gardiner, Ryan Ling, Yiong-Huak Chan, Jose Porcel, Y C Gary Lee, Chia-Meng Teoh, Mei-Fong Liew, Jeevesh Kapur, Seow-Ping Low, Pyng Lee","doi":"10.1111/resp.14780","DOIUrl":"10.1111/resp.14780","url":null,"abstract":"Background: Fifty years since its inception, Light's criteria have aided in classifying pleural effusions (PEs) as exudates if 1 or more criteria are met. Thoracic ultrasound (US) emerges as a non-invasive technique for point of care use especially if pleural procedures are contemplated.Objective: We aimed to develop a score based on radiological and US features that could separate exudates from transudates without serum and pleural fluid biochemical tests necessary for Light's criteria.Methods: A prospective review of consecutive patients with PE who underwent thoracocentesis was performed. CXRs were evaluated for laterality followed by US for echogenicity, pleural nodularity, thickening and septations. PE was classified as exudate or transudate according to Light's criteria and corroborated with albumin gradient. A score combining radiological and US features was developed.Results: We recruited 201 patients with PE requiring thoracocentesis. Mean age was 64 years, 51% were females, 164 (81.6%) were exudates, and 37 (18.4%) were transudates. Assigning 1-point for Diaphragmatic nodularity, Unilateral, Echogenicity, Pleural Thickening and Septations, DUETS ranged from 1 to 5. DUETS ≥2 indicated high likelihood for exudate (PPV 98.8%, NPV 100%) with 1% misclassification versus 6.9% using Light's criteria (p < 0.001).Conclusion: DUETS separated exudates from transudates with good accuracy, and could obviate paired serum and pleural fluid tests necessary for Light's criteria computation. Our study reflected real world practice where DUETS performed better than Light's criteria for PE that arose from more than one disease processes, and in the evaluation of patients with PE who have received diuretics.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":"976-984"},"PeriodicalIF":6.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A 5-year perspective on coronavirus diseases 2019 (COVID-19). 冠状病毒疾病 5 年展望 2019（COVID-19）。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-09-03 DOI: 10.1111/resp.14826

David S C Hui, Alimuddin Zumla

引用次数: 0

From light to sound: Ultrasound outshines Light's criteria for pleural effusions classification. 从光到声：超声波优于 Light 的胸腔积液分类标准。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-08-28 DOI: 10.1111/resp.14825

Arash Badiei

引用次数: 0

Computed tomography mucus plugs and airway tree structure in patients with chronic obstructive pulmonary disease: Associations with airflow limitation, health-related independence and mortality. 慢性阻塞性肺病患者的计算机断层扫描粘液栓和气道树结构：与气流受限、健康相关独立性和死亡率的关系。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-06-24 DOI: 10.1111/resp.14776

Naoya Tanabe, Kaoruko Shimizu, Hiroshi Shima, Nobuyasu Wakazono, Yusuke Shiraishi, Kunihiko Terada, Satoru Terada, Tsuyoshi Oguma, Ryo Sakamoto, Masaru Suzuki, Hironi Makita, Atsuyasu Sato, Susumu Sato, Masaharu Nishimura, Satoshi Konno, Toyohiro Hirai

{"title":"Computed tomography mucus plugs and airway tree structure in patients with chronic obstructive pulmonary disease: Associations with airflow limitation, health-related independence and mortality.","authors":"Naoya Tanabe, Kaoruko Shimizu, Hiroshi Shima, Nobuyasu Wakazono, Yusuke Shiraishi, Kunihiko Terada, Satoru Terada, Tsuyoshi Oguma, Ryo Sakamoto, Masaru Suzuki, Hironi Makita, Atsuyasu Sato, Susumu Sato, Masaharu Nishimura, Satoshi Konno, Toyohiro Hirai","doi":"10.1111/resp.14776","DOIUrl":"10.1111/resp.14776","url":null,"abstract":"Background and objective: Mucus plugs and underlying airway tree structure can affect airflow limitation and prognosis in patients with chronic obstructive pulmonary disease (COPD), but their relative roles are unclear. This study used two COPD cohorts to examine whether mucus plugs on computed tomography (CT) were associated with airflow limitation and clinical outcomes independent of other airway structural changes and emphysema.Methods: Based on visual CT assessment, patients with mucus plugs in 0, 1-2 and ≥3 lung segments were assigned to no-, low- and high-mucus groups. Loss of health-related independence and mortality were prospectively recorded for 3 and 10 years in the Kyoto-Himeji and Hokkaido cohorts, respectively. The percentages of the wall area of the central airways (WA%), total airway count (TAC) and emphysema were quantified on CT.Results: Of 199 and 96 patients in the Kyoto-Himeji and Hokkaido cohorts, 34% and 30%, respectively, had high mucus scores. In both cohorts, TAC was lower in the high-mucus group than in the no-mucus group, whereas their emphysema severity did not differ. High mucus score and low TAC were independently associated with airflow limitation after adjustment for WA% and emphysema. In multivariable models adjusted for WA% and emphysema, TAC, rather than mucus score, was associated with a greater rate of loss of independence, whereas high mucus score, rather than TAC, was associated with increased mortality.Conclusion: Mucus plugs and lower airway branch count on CT had distinct roles in airflow limitation, health-related independence and mortality in patients with COPD.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":"951-961"},"PeriodicalIF":6.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Picture this: The future of imaging biomarkers in COPD. 想象一下：慢性阻塞性肺病成像生物标志物的未来。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-08-01 DOI: 10.1111/resp.14808

Cara Flynn, Chris Brightling

引用次数: 0

Correlations between blood vessel distribution, lung function and structural change in idiopathic pulmonary fibrosis. 特发性肺纤维化中血管分布、肺功能和结构变化之间的相关性。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-08-15 DOI: 10.1111/resp.14811

Po-Wei Hu, Chun-Ku Chen, Yi-Han Hsiao, Ching-Yao Weng, Ying-Chi Lee, Kang-Cheng Su, Jia-Yih Feng, Kun-Ta Chou, Diahn-Warng Perng, Hsin-Kuo Ko

{"title":"Correlations between blood vessel distribution, lung function and structural change in idiopathic pulmonary fibrosis.","authors":"Po-Wei Hu, Chun-Ku Chen, Yi-Han Hsiao, Ching-Yao Weng, Ying-Chi Lee, Kang-Cheng Su, Jia-Yih Feng, Kun-Ta Chou, Diahn-Warng Perng, Hsin-Kuo Ko","doi":"10.1111/resp.14811","DOIUrl":"10.1111/resp.14811","url":null,"abstract":"Background and objective: Correlations between the image analysis of CT scan, lung function and quality of life in patients with idiopathic pulmonary fibrosis (IPF) remain unclear. This study aimed to investigate the impacts of pulmonary blood-vessel distribution and the extent of fibrosis on the lung function and quality of life of patients with IPF.Methods: Patients were enrolled in an IPF registry and had completed pulmonary function tests, chest HRCT, St. George Respiratory Questionnaire (SGRQ) and echocardiography. Pulmonary blood-vessel distribution, specific image-derived airway volume (siVaw) and fibrosis extent (siVfib) were quantitatively calculated by functional respiratory imaging on HRCT.Results: The study subjects were categorized into DLco <40% pred. (n = 40) and DLco ≥40% pred. (n = 19) groups. Patients with DLco <40% pred. had significantly higher scores of SGRQ, composite physiologic index (CPI), exercise oxygen desaturation (∆SpO2), siVaw, lower FVC% pred. and 6-minute walking distance% pred. The proportion of small blood vessels in the upper lobes (BV5PR-UL) was significantly correlated with CPI, DLco % Pred., FVC% pred., SGRQ and ∆SpO2. Only BV5PR-UL had a significant impact on all indices but not BV5PR in the lower lobes (BV5PR-LL). siVfib was significantly negatively correlated with BV5PR-UL, DLco% pred. and FVC% pred., as well as positively correlated with CPI, ∆SpO2 and siVaw.Conclusion: BV5PR-UL and siVfib had significant correlations with lung function and may become important indicators to assess the severity of IPF and the impact on quality of life.","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":"962-968"},"PeriodicalIF":6.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141988723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

APSR Annual Conference - 28^th Congress of the Asian Pacific Society of Respirology, 7-10 November 2024, Hong Kong. 亚太呼吸病学会年会 - 第 28 届亚太呼吸病学会大会，2024 年 11 月 7-10 日，香港。

IF 5.3 2区医学

Respirology Pub Date : 2024-11-01 DOI: 10.1111/resp.14835

引用次数: 0

Letter from Hong Kong: Vaccination trends for respiratory viral infections in Hong Kong. 香港来信：香港呼吸道病毒感染疫苗接种趋势。

IF 6.6 2区医学

Respirology Pub Date : 2024-11-01 Epub Date: 2024-08-27 DOI: 10.1111/resp.14824

Ken Ka Pang Chan, David Shu Cheong Hui

引用次数: 0

Uncontrolled mild-to-moderate asthma may not be mild or moderate, or even asthma: The benefits of early phenotyping. 不受控制的轻度至中度哮喘可能不是轻度或中度，甚至不是哮喘：早期表型的好处。

IF 6.6 2区医学