Molecular Ecology最新文献_第10页

Environmental microbes promote phenotypic plasticity in reproduction and sleep behaviour 环境微生物促进生殖和睡眠行为的表型可塑性

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-14 DOI: 10.1111/mec.17095

Mélisandre A. Téfit, Tifanny Budiman, Adrianna Dupriest, Joanne Y. Yew

{"title":"Environmental microbes promote phenotypic plasticity in reproduction and sleep behaviour","authors":"Mélisandre A. Téfit, Tifanny Budiman, Adrianna Dupriest, Joanne Y. Yew","doi":"10.1111/mec.17095","DOIUrl":"https://doi.org/10.1111/mec.17095","url":null,"abstract":"The microbiome has been hypothesized as a driving force of phenotypic variation in host organisms that is capable of extending metabolic processes, altering development and in some cases, conferring novel functions that are critical for survival. Only a few studies have directly shown a causal role for the environmental microbiome in altering host phenotypic features. To assess the extent to which environmental microbes induce variation in host life-history traits and behaviour, we inoculated axenic Drosophila melanogaster with microbes isolated from drosophilid populations collected from two different field sites and generated two populations with distinct bacterial and fungal profiles. We show that microbes isolated from environmental sites with modest abiotic differences induce large variation in host reproduction, fatty acid levels, stress tolerance and sleep behaviour. Importantly, clearing microbes from each experimental population removed the phenotypic differences. The results support the causal role of environmental microbes as drivers of host phenotypic plasticity and potentially, rapid adaptation and evolution.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"32 18","pages":"5186-5200"},"PeriodicalIF":4.9,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.17095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6224508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Holocentric repeat landscapes: From micro-evolutionary patterns to macro-evolutionary associations with karyotype evolution. 全新中心重复景观:从微观进化模式到与核型进化相关的宏观进化。

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-14 DOI: 10.1111/mec.17100

Camille Cornet, Pablo Mora, Hannah Augustijnen, Petr Nguyen, Marcial Escudero, Kay Lucek

{"title":"Holocentric repeat landscapes: From micro-evolutionary patterns to macro-evolutionary associations with karyotype evolution.","authors":"Camille Cornet, Pablo Mora, Hannah Augustijnen, Petr Nguyen, Marcial Escudero, Kay Lucek","doi":"10.1111/mec.17100","DOIUrl":"https://doi.org/10.1111/mec.17100","url":null,"abstract":"Repetitive elements can cause large-scale chromosomal rearrangements, for example through ectopic recombination, potentially promoting reproductive isolation and speciation. Species with holocentric chromosomes, that lack a localized centromere, might be more likely to retain chromosomal rearrangements that lead to karyotype changes such as fusions and fissions. This is because chromosome segregation during cell division should be less affected than in organisms with a localized centromere. The relationships between repetitive elements and chromosomal rearrangements and how they may translate to patterns of speciation in holocentric organisms are though poorly understood. Here, we use a reference-free approach based on low-coverage short-read sequencing data to characterize the repeat landscape of two independently evolved holocentric groups: Erebia butterflies and Carex sedges. We consider both micro- and macro-evolutionary scales to investigate the repeat landscape differentiation between Erebia populations and the association between repeats and karyotype changes in a phylogenetic framework for both Erebia and Carex. At a micro-evolutionary scale, we found population differentiation in repeat landscape that increases with overall intraspecific genetic differentiation among four Erebia species. At a macro-evolutionary scale, we found indications for an association between repetitive elements and karyotype changes along both Erebia and Carex phylogenies. Altogether, our results suggest that repetitive elements are associated with the level of population differentiation and chromosomal rearrangements in holocentric clades and therefore likely play a role in adaptation and potentially species diversification.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9993271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A comparison of genomic diversity and demographic history of the North Atlantic and Southwest Atlantic southern right whales 北大西洋和西南大西洋南露脊鲸基因组多样性和繁殖史比较

IF 4.5 1区生物学

Molecular Ecology Pub Date : 2023-08-14 DOI: 10.1111/mec.17099

Carla A. Crossman, Michael C. Fontaine, Timothy R. Frasier

{"title":"A comparison of genomic diversity and demographic history of the North Atlantic and Southwest Atlantic southern right whales","authors":"Carla A. Crossman, Michael C. Fontaine, Timothy R. Frasier","doi":"10.1111/mec.17099","DOIUrl":"10.1111/mec.17099","url":null,"abstract":"Right whales (genus Eubalaena) were among the first, and most extensively pursued, targets of commercial whaling. However, understanding the impacts of this persecution requires knowledge of the demographic histories of these species prior to exploitation. We used deep whole genome sequencing (~40×) of 12 North Atlantic (E. glacialis) and 10 Southwest Atlantic southern (E. australis) right whales to quantify contemporary levels of genetic diversity and infer their demographic histories over time. Using coalescent- and identity-by-descent–based modelling to estimate ancestral effective population sizes from genomic data, we demonstrate that North Atlantic right whales have lived with smaller effective population sizes (Ne) than southern right whales in the Southwest Atlantic since their divergence and describe the decline in both populations around the time of whaling. North Atlantic right whales exhibit reduced genetic diversity and longer runs of homozygosity leading to higher inbreeding coefficients compared to the sampled population of southern right whales. This study represents the first comprehensive assessment of genome-wide diversity of right whales in the western Atlantic and underscores the benefits of high coverage, genome-wide datasets to help resolve long-standing questions about how historical changes in effective population size over different time scales shape contemporary diversity estimates. This knowledge is crucial to improve our understanding of the right whales' history and inform our approaches to address contemporary conservation issues. Understanding and quantifying the cumulative impact of long-term small Ne, low levels of diversity and recent inbreeding on North Atlantic right whale recovery will be important next steps.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"33 20","pages":""},"PeriodicalIF":4.5,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.17099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9991217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Philopatry influences the genetic population structure of the blacktip shark (Carcharhinus limbatus) at multiple spatial scales 亲缘关系在多个空间尺度上影响黑鳍鲨(Carcharhinus limbatus)的遗传种群结构

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-11 DOI: 10.1111/mec.17096

Dominic G. Swift, Shannon J. O'Leary, R. Dean Grubbs, Bryan S. Frazier, Andrew T. Fields, Jayne M. Gardiner, J. Marcus Drymon, Dana M. Bethea, Tonya R. Wiley, David S. Portnoy

{"title":"Philopatry influences the genetic population structure of the blacktip shark (Carcharhinus limbatus) at multiple spatial scales","authors":"Dominic G. Swift, Shannon J. O'Leary, R. Dean Grubbs, Bryan S. Frazier, Andrew T. Fields, Jayne M. Gardiner, J. Marcus Drymon, Dana M. Bethea, Tonya R. Wiley, David S. Portnoy","doi":"10.1111/mec.17096","DOIUrl":"https://doi.org/10.1111/mec.17096","url":null,"abstract":"Understanding how interactions among microevolutionary forces generate genetic population structure of exploited species is vital to the implementation of management policies that facilitate persistence. Philopatry displayed by many coastal shark species can impact gene flow and facilitate selection, and has direct implications for the spatial scales of management. Here, genetic structure of the blacktip shark (Carcharhinus limbatus) was examined using a mixed-marker approach employing mitochondrial control region sequences and 4339 SNP-containing loci generated using ddRAD-Seq. Genetic variation was assessed among young-of-the-year sampled in 11 sites in waters of the United States in the western North Atlantic Ocean, including the Gulf of Mexico. Spatial and environmental analyses detected 68 nuclear loci putatively under selection, enabling separate assessments of neutral and adaptive genetic structure. Both mitochondrial and neutral SNP data indicated three genetically distinct units—the Atlantic, eastern Gulf, and western Gulf—that align with regional stocks and suggest regional philopatry by males and females. Heterogeneity at loci putatively under selection, associated with temperature and salinity, was observed among sites within Gulf units, suggesting local adaptation. Furthermore, five pairs of siblings were identified in the same site across timescales corresponding with female reproductive cycles. This indicates that females re-used a site for parturition, which has the potential to facilitate the sorting of adaptive variation among neighbouring sites. The results demonstrate differential impacts of microevolutionary forces at varying spatial scales and highlight the importance of conserving essential habitats to maintain sources of adaptive variation that may buffer species against environmental change.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"32 18","pages":"4953-4970"},"PeriodicalIF":4.9,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6186223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Seasonal development of a tidal mixing front drives shifts in community structure and diversity of bacterioplankton 潮汐混合锋的季节性发展驱动了群落结构和浮游细菌多样性的变化

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-09 DOI: 10.1111/mec.17097

Nathan G. King, Sophie-B Wilmes, Samuel S. Browett, Amy Healey, Allan D. McDevitt, Niall J. McKeown, Ronan Roche, Ilze Skujina, Dan A. Smale, Jamie M. Thorpe, Shelagh Malham

{"title":"Seasonal development of a tidal mixing front drives shifts in community structure and diversity of bacterioplankton","authors":"Nathan G. King, Sophie-B Wilmes, Samuel S. Browett, Amy Healey, Allan D. McDevitt, Niall J. McKeown, Ronan Roche, Ilze Skujina, Dan A. Smale, Jamie M. Thorpe, Shelagh Malham","doi":"10.1111/mec.17097","DOIUrl":"https://doi.org/10.1111/mec.17097","url":null,"abstract":"Bacterioplankton underpin biogeochemical cycles and an improved understanding of the patterns and drivers of variability in their distribution is needed to determine their wider functioning and importance. Sharp environmental gradients and dispersal barriers associated with ocean fronts are emerging as key determinants of bacterioplankton biodiversity patterns. We examined how the development of the Celtic Sea Front (CF), a tidal mixing front on the Northwest European Shelf affects bacterioplankton communities. We performed 16S-rRNA metabarcoding on 60 seawater samples collected from three depths (surface, 20 m and seafloor), across two research cruises (May and September 2018), encompassing the intra-annual range of the CF intensity. Communities above the thermocline of stratified frontal waters were clearly differentiated and less diverse than those below the thermocline and communities in the well-mixed waters of the Irish Sea. This effect was much more pronounced in September, when the CF was at its peak intensity. The stratified zone likely represents a stressful environment for bacterioplankton due to a combination of high temperatures and low nutrients, which fewer taxa can tolerate. Much of the observed variation was driven by Synechococcus spp. (cyanobacteria), which were more abundant within the stratified zone and are known to thrive in warm oligotrophic waters. Synechococcus spp. are key contributors to global primary productivity and carbon cycling and, as such, variability driven by the CF is likely to influence regional biogeochemical processes. However, further studies are required to explicitly link shifts in community structure to function and quantify their wider importance to pelagic ecosystems.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"32 18","pages":"5201-5210"},"PeriodicalIF":4.9,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.17097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6054312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid turnover and evolution of sex-determining regions in Sebastes rockfishes sebases岩鱼性别决定区域的快速更替和进化

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-07 DOI: 10.1111/mec.17090

Nathan T. B. Sykes, Sree Rohit Raj Kolora, Peter H. Sudmant, Gregory L. Owens

{"title":"Rapid turnover and evolution of sex-determining regions in Sebastes rockfishes","authors":"Nathan T. B. Sykes, Sree Rohit Raj Kolora, Peter H. Sudmant, Gregory L. Owens","doi":"10.1111/mec.17090","DOIUrl":"https://doi.org/10.1111/mec.17090","url":null,"abstract":"Nature has evolved a wealth of sex determination (SD) mechanisms, driven by both genetic and environmental factors. Recent studies of SD in fishes have shown that not all taxa fit the classic paradigm of sex chromosome evolution and diverse SD methods can be found even among closely related species. Here, we apply a suite of genomic approaches to investigate sex-biased genomic variation in eight species of Sebastes rockfish found in the northeast Pacific Ocean. Using recently assembled chromosome-level rockfish genomes, we leverage published sequence data to identify disparate sex chromosomes and sex-biased loci in five species. We identify two putative male sex chromosomes in S. diaconus, a single putative sex chromosome in the sibling species S. carnatus and S. chrysomelas, and an unplaced sex determining contig in the sibling species S. miniatus and S. crocotulus. Our study provides evidence for disparate means of sex determination within a recently diverged set of species and sheds light on the diverse origins of sex determination mechanisms present in the animal kingdom.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"32 18","pages":"5013-5027"},"PeriodicalIF":4.9,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.17090","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6130549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Climate has contributed to population diversification of Daphnia galeata across Eurasia 气候影响了欧亚大陆水蚤种群的多样性

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-07 DOI: 10.1111/mec.17094

Zhixiong Deng, Xiuping Zhang, Justyna Wolinska, David Blair, Wei Hu, Mingbo Yin

{"title":"Climate has contributed to population diversification of Daphnia galeata across Eurasia","authors":"Zhixiong Deng, Xiuping Zhang, Justyna Wolinska, David Blair, Wei Hu, Mingbo Yin","doi":"10.1111/mec.17094","DOIUrl":"https://doi.org/10.1111/mec.17094","url":null,"abstract":"Climate is a fundamental abiotic factor that plays a key role in driving the evolution, distribution and population diversification of species. However, there have been few investigations of genomic signatures of adaptation to local climatic conditions in cladocerans. Here, we have provided the first high-quality chromosome-level genome assembly (~143 Mb, scaffold N50 12.6 Mb) of the waterflea, Daphnia galeata, and investigated genomic variation in 22 populations from Central Europe and Eastern China. Our ecological-niche models suggested that the historic distribution of D. galeata in Eurasia was significantly affected by Quaternary climate fluctuations. We detected pronounced genomic and morphometric divergences between European and Chinese D. galeata populations. Such divergences could be partly explained by genomic signatures of thermal adaptation to distinct climate regimes: a set of candidate single-nucleotide polymorphisms (SNPs) potentially associated with climate were detected. These SNPs were in genes significantly enriched in the Gene ontology terms “determination of adult lifespan” and “translation repressor activity”, and especially, mthl5 and SOD1 involved in the IIS pathway, and EIF4EBP2 involved in the target of the rapamycin signalling pathway. Our study indicates that certain alleles might be associated with particular temperature regimes, playing a functional role in shaping the population structure of D. galeata at a large geographical scale. These results highlight the potential role of molecular variation in the response to climate variation, in the context of global climate change.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"32 18","pages":"5110-5124"},"PeriodicalIF":4.9,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"6130545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selection on standing genetic variation mediates convergent evolution in extremophile fish 直立遗传变异的选择介导了极端生物的趋同进化

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-07 DOI: 10.1111/mec.17081

Kara Ryan, Ryan Greenway, Jake Landers, Lenin Arias-Rodriguez, Michael Tobler, Joanna L. Kelley

{"title":"Selection on standing genetic variation mediates convergent evolution in extremophile fish","authors":"Kara Ryan, Ryan Greenway, Jake Landers, Lenin Arias-Rodriguez, Michael Tobler, Joanna L. Kelley","doi":"10.1111/mec.17081","DOIUrl":"https://doi.org/10.1111/mec.17081","url":null,"abstract":"Hydrogen sulfide is a toxic gas that disrupts numerous biological processes, including energy production in the mitochondria, yet fish in the Poecilia mexicana species complex have independently evolved sulfide tolerance several times. Despite clear evidence for convergence at the phenotypic level in these fishes, it is unclear if the repeated evolution of hydrogen sulfide tolerance is the result of similar genomic changes. To address this gap, we used a targeted capture approach to sequence genes associated with sulfide processes and toxicity from five sulfidic and five nonsulfidic populations in the species complex. By comparing sequence variation in candidate genes to a reference set, we identified similar population structure and differentiation, suggesting that patterns of variation in most genes associated with sulfide processes and toxicity are due to demographic history and not selection. But the presence of tree discordance for a subset of genes suggests that several loci are evolving divergently between ecotypes. We identified two differentiation outlier genes that are associated with sulfide detoxification in the mitochondria that have signatures of selection in all five sulfidic populations. Further investigation into these regions identified long, shared haplotypes among sulfidic populations. Together, these results reveal that selection on standing genetic variation in putatively adaptive genes may be driving phenotypic convergence in this species complex.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"32 18","pages":"5042-5054"},"PeriodicalIF":4.9,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.17081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5743244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain and antennal transcriptomes of host ants reveal potential links between behaviour and the functioning of socially parasitic colonies 寄主蚂蚁的大脑和触角转录组揭示了社会寄生群体行为和功能之间的潜在联系

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-04 DOI: 10.1111/mec.17092

Marah Stoldt, Erwann Collin, Maide Nesibe Macit, Susanne Foitzik

{"title":"Brain and antennal transcriptomes of host ants reveal potential links between behaviour and the functioning of socially parasitic colonies","authors":"Marah Stoldt, Erwann Collin, Maide Nesibe Macit, Susanne Foitzik","doi":"10.1111/mec.17092","DOIUrl":"https://doi.org/10.1111/mec.17092","url":null,"abstract":"Insect social parasites are characterized by exploiting the hosts' social behaviour. Why exactly hosts direct their caring behaviour towards these parasites and their offspring remains largely unstudied. One hypothesis is that hosts do not perceive their social environment as altered and accept the parasitic colony as their own. We used the ant Leptothorax acervorum, host of the dulotic, obligate social parasite Harpagoxenus sublaevis, to shed light on molecular mechanisms underlying behavioural exploitation by contrasting tissue-specific transcriptomes in young host workers. Host pupae were experimentally (re-)introduced into fragments of their original, another conspecific, heterospecific or parasitic colony. Brain and antennal mRNA was extracted and sequenced from adult ants after they had lived in the experimental colony for at least 50 days after eclosion. The resulting transcriptomes of L. acervorum revealed that ants were indeed affected by their social environment. Host brain transcriptomes were altered by the presence of social parasites, suggesting that the parasitic environment influences brain activity, which may be linked to behavioural changes. Transcriptional activity in the antennae changed most with the presence of unrelated individuals, regardless of whether they were conspecifics or parasites. This suggests early priming of odour perception, which was further supported by sensory perception of odour as an enriched function of differentially expressed genes. Furthermore, gene expression in the antennae, but not in the brain corresponded to ant worker behaviour before sampling. Our study demonstrated that the exploitation of social behaviours by brood parasites correlates with transcriptomic alterations in the central and peripheral nervous systems.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"32 18","pages":"5170-5185"},"PeriodicalIF":4.9,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.17092","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5691743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parasite manipulation of host phenotypes inferred from transcriptional analyses in a trematode-amphipod system 从吸虫-片足类动物系统的转录分析推断，寄生虫操纵宿主表型

IF 4.9 1区生物学

Molecular Ecology Pub Date : 2023-08-04 DOI: 10.1111/mec.17093

David M. Rand, Joaquin C. B. Nunez, Shawn Williams, Stephen Rong, John T. Burley, Kimberly B. Neil, Adam N. Spierer, Wilson McKerrow, David S. Johnson, Yevgeniy Raynes, Thomas J. Fayton, Nicholas Skvir, David A. Ferranti, Maya Greenhill Zeff, Amanda Lyons, Naima Okami, David M. Morgan, Kealohanuiopuna Kinney, Bianca R. P. Brown, Anne E. Giblin, Zoe G. Cardon

{"title":"Parasite manipulation of host phenotypes inferred from transcriptional analyses in a trematode-amphipod system","authors":"David M. Rand, Joaquin C. B. Nunez, Shawn Williams, Stephen Rong, John T. Burley, Kimberly B. Neil, Adam N. Spierer, Wilson McKerrow, David S. Johnson, Yevgeniy Raynes, Thomas J. Fayton, Nicholas Skvir, David A. Ferranti, Maya Greenhill Zeff, Amanda Lyons, Naima Okami, David M. Morgan, Kealohanuiopuna Kinney, Bianca R. P. Brown, Anne E. Giblin, Zoe G. Cardon","doi":"10.1111/mec.17093","DOIUrl":"https://doi.org/10.1111/mec.17093","url":null,"abstract":"Manipulation of host phenotypes by parasites is hypothesized to be an adaptive strategy enhancing parasite transmission across hosts and generations. Characterizing the molecular mechanisms of manipulation is important to advance our understanding of host–parasite coevolution. The trematode (Levinseniella byrdi) is known to alter the colour and behaviour of its amphipod host (Orchestia grillus) presumably increasing predation of amphipods which enhances trematode transmission through its life cycle. We sampled 24 infected and 24 uninfected amphipods from a salt marsh in Massachusetts to perform differential gene expression analysis. In addition, we constructed novel genomic tools for O. grillus including a de novo genome and transcriptome. We discovered that trematode infection results in upregulation of amphipod transcripts associated with pigmentation and detection of external stimuli, and downregulation of multiple amphipod transcripts implicated in invertebrate immune responses, such as vacuolar ATPase genes. We hypothesize that suppression of immune genes and the altered expression of genes associated with coloration and behaviour may allow the trematode to persist in the amphipod and engage in further biochemical manipulation that promotes transmission. The genomic tools and transcriptomic analyses reported provide new opportunities to discover how parasites alter diverse pathways underlying host phenotypic changes in natural populations.","PeriodicalId":210,"journal":{"name":"Molecular Ecology","volume":"32 18","pages":"5028-5041"},"PeriodicalIF":4.9,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.17093","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5693756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0