Indonesian Journal of Obstetrics & Gynecology Science最新文献

{"title":"Maturation of Vaginal Epithelium and Dyspareunia Symptoms in Equol Producing and Non-Producing Menopausal Women","authors":"T. H. Madjid, Nurlina Juniar, Dian Tjahyadi, B. Dewayani, W. Permadi, B. Purwara, H. Susiarno","doi":"10.24198/obgynia.v3n1.194","DOIUrl":"https://doi.org/10.24198/obgynia.v3n1.194","url":null,"abstract":"Introduction : Equol is a metabolite of soy isoflavon called daidzein which is produced by gastrointestinal tract bacteria. This research aims to analyze the maturation of vaginal epithelium and dyspareunia symptoms in producing and non-producing equol menopausal women. Method : This is a cross sectional research. Subject was a community of menopausal women who fulfilled inclusion criteria. Subjects were asked to sign a written informed consent. Subjects underwent vaginal epithelium maturation assessment and were asked whether she experienced dyspareunia. Research was conducted in January 2017. Result : There was a significant difference on the maturation of vaginal epithelium and dyspareunia symptoms between equol producing and non-producing women (p < 0.05). This research found that in equol producing menopausal women, there was a shift-to-the-right vaginal epithelium maturation with more superficial cells compared to parabasal cells produced and less dyspareunia. Meanwhile, in women who did not produce equol, there was a shift-to-the-left vaginal epithelium maturation with more parabasal cells compared to superficial cells produced and more dyspareunia. Conclusion : In equol producing menopausal women, vaginal epithelium will undergo a shift-to-the-right maturation, with more superficial cells produced compared to women who did not produce equol. Maturasi Epitel Vagina dan Gejala Dispareunia pada Wanita Menopause yang Menghasilkan Equol dan Wanita yang Tidak Menghasilkan Equol Abstrak Pendahuluan : Equol adalah metabolit isoflavon kedelai yang disebut daidzein yang diproduksi oleh bakteri saluran pencernaan. Penelitian ini bertujuan untuk menganalisis maturasi epitel vagina dan gejala dispareunia pada wanita menopause yang memproduksi dan tidak memproduksi equol. Metode : Penelitian ini merupakan penelitian cross sectional. Subjek penelitian adalah sekelompok wanita menopause yang memenuhi kriteria inklusi. Subjek diminta untuk menandatangani persetujuan tertulis dan menjalani penilaian maturasi epitel vagina dan ditanya apakah mengalami dispareunia. Penelitian dilakukan pada Januari 2017. Hasil : Terdapat perbedaan yang signifikan pada maturasi epitel vagina dan gejala dispareunia antara wanita yang memproduksi equol dan yang tidak memproduksi (p <0,05). Pada wanita menopause yang memproduksi equol, terjadi pematangan epitel vagina shift-to-the-right disertai produksi sel superfisial yang lebih banyak dibandingkan sel parabasal dan lebih sedikit gejala dispareunia. Sementara itu, pada wanita yang tidak menghasilkan equol, terjadi pergeseran shift-to-the-left maturasi epitel vagina dengan produksi sel parabasal lebih banyak dibandingkan sel superfisial dan lebih sering gejala dispareunia. Kesimpulan: Wanita menopause yang memproduksi equol mengalami maturasi epitel vagina shift-to-the-right disertai produksi sel superfisial yang lebih banyak dibandingkan dengan wanita menopause yang tidak memproduksi equol. Kata kunci : Dyspareunia; equol; mat","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134055223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hubungan Kadar Asam Urat, Laktat Dehidrogenase, Aspartat Aminotransferase Serum Penderita Preeklamsi Berat Disertai Komplikasi dan tanpa Komplikasi","authors":"Galih Apriadi, Budi Handono, Akhmad Yogi Pramatirta, J. Effendi, Tita Husnitawati Madjid, Adhi Pribadi","doi":"10.24198/OBGYNIA/V3N1.195","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N1.195","url":null,"abstract":"Tujuan : penelitian ini untuk mencari perbedaan kadar asam urat, laktat dehydrogenase (LDH) dan aspartat aminotransferase (AST) pada serum penderita preeklamsi berat disertai komplikasi dan tanpa komplikasi dan mengukur kuatnya hubungan peningkatan kadar asam urat, LDH dan AST dengan peningkatan risiko terjadinya komplikasi pada pasien preeklamsi berat. Metode : Rancangan penelitian ini adalah penelitian comparative cross sectional dengan metode consecutive sampling. Subjek penelitian adalah penderita preeklamsi berat disertai komplikasi dan tanpa komplikasi (n=68). Hasil : Hasil penelitian didapatkan perbedaan kadar asam urat, LDH dan AST pada kedua kelompok secara bermakna dengan nilai p ≤ 0,05. Peningkatan kadar asam urat, LDH dan AST berhubungan dengan peningkatan risiko terjadinya komplikasi dengan nilai cut off kadar asam urat > 6,5 mg/dL sebesar 33 kali, LDH > 573 U/L sebesar 8,95 kali dan AST > 30 U/L sebesar 5,19 kali. Jika terjadi peningkatan seluruh kadar asam urat, LDH dan AST diatas nilai cut off maka risiko terjadinya komplikasi sebesar 98,1%. Kesimpulan : Penelitian ini menyimpulkan kadar asam urat, LDH, AST pada preeklamsi berat disertai komplikasi lebih tinggi dibandingkan preeklamsi berat tanpa komplikasi dan peningkatan kadar asam urat, LDH, AST berhubungan dengan peningkatan risiko terjadinya komplikasi pada preeklamsi berat. Relations of Uric Acid, Lactat Dehydrogenase, and Aspartat Aminotransferase Serum LevelIn Severe Preeclampsia with and Without Complications Abstract Objective : This study compared level of uric acid, LDH, and AST level between severe preeclampsia patients with complication and without complication, and measured correlation between the rise level of uric acid, LDH and AST towards the increased risk of complication in patient with severe preeclampsia. Method : The study design was comparative cross sectional study with consecutive sampling method that compare the results of laboratorium uric acid, LDH, AST between complications and without complications group. Subjects of this study were severe preeclampsia patients with and without complication that fulfilled study criteria (n=68). Result:    It is revealed that the differences level of uric acid, LDH, and AST in both groups were significant with p value ≤ 0.05. Increase level of uric acid, LDH, and AST were related to inreased risk of complication in severe preeclampsia occurence with cut off point of uric acid level of > 6.5 mg/dL by 33 times, LDH level of > 573 U/L by 8.95 times, and AST level of > 30 U/L by 5.19 times. If all uric acid, LDH, and AST level rise above the cut off value so the risk of complication of severe preeclampsia will rise by 98.1%. Conclusion : It is concluded that level of uric acid, LDH, and AST in severe preeclampsia with complication were higher than severe preeclampsia without complication and the rise of uric acid, LDH, and AST were related with the rise of complication risk on severe preeclampsia. Key word : Severe preecl","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115368524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antley-Bixler Syndrome: A Case Report and Literature Review","authors":"H. Hermanto, I. Rachman","doi":"10.24198/OBGYNIA/V3N1.181","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N1.181","url":null,"abstract":"Sindroma Antley-Bixler pertama kali dikemukakan oleh Ray Antley dan David Bixler tahun 1975. Sindroma ini jarang dan berhubungan dengan kelainan perkembangan tulang dan kartilago sehingga sering disebut multisynostotic osteodysgenesis syndrome. Craniosynostosis dan synostosis radiohumeral merupakan temuan yang paling konsisten. Penyebab sindroma ini belum jelas, diduga karena adanya mutasi genetik. Laporan kasus :Seorang ibu 22 tahun G2P1A0 dirujuk ke poliklinik obstetri dan ginekologi RSUP dr.Sardjito pada usia kehamilan 32-33 minggu untuk pemeriksaan antenatal dengan kecurigaan fetal craniosynostosis dan ventriculomegaly. Pada usia kehamilan 38 minggu, bayi lahir dengan craniosynostosis, ocular hypertelorism, disertai syndactily digiti II-IV pedis dextra et sinistra dengan diagnosis sementara sindroma Apert. Pemeriksaan penunjang yakni MSCT scan kranial dan foto rontgen regio artikulatio cubiti anteroposterior dan lateral menunjukan adanya craniosynostosis dan synostosis radioulna dan radiohumeral bilateral mengarahkan diagnosis sindroma Antley-Bixler. Bayi dipulangkan setelah 24 hari perawatan. Saat ini bayi masih menjalani perawatan berkala di instalasi rawat jalan ilmu kesehatan mata dan bedah saraf RSUP Dr. Sardjito Kesimpulan: Laporan kasus ini bertujuan untuk membahas penegakan diagnosis, tatalaksana yang telah dilakukan dan rencana tatalaksana yang akan datang.  Abstract Introduction : Antley-Bixler syndrome (ABS) was first described by Ray Antley and David Bixler in 1975. The syndrome is rare and characterized by abnormalities of bone and cartilage development (“syndrome of multisynostotic osteogenesis”). Craniosynostosis and radiohumeral synostosis are the most consistent findings. The cause of this syndrome is unclear, but genetic mutations are suspected. Case report: A 22-year-old female G2P1A0 was referred to the obstetric and gynecology outpatient clinic at RSUP Dr. Sardjito at 32-33 weeks of gestation for antenatal care and further evaluation due to suspected fetal craniosynostosis and ventriculomegaly. At 38 weeks' gestation, the baby was born with craniosynostosis, ocular hypertelorism, and syndactily digiti II-IV pedis dextra and sinistra, suspected Apert syndrome. Further investigation by using radiologic examination (cranial MSCT scan and X-ray at anteroposterior and lateral articulation cubital) revealed craniosynostosis, bilateral radioulna and radiohumeral synostosis, directed the diagnosis to Antley-Bixler syndrome. The baby was discharged after 24 days of admission. Currently, the baby is still undergoing regular evaluation and treatment at the Ophthalmology and Neurosurgery outpatient department at RSUP Dr. Sardjito Conclusion: The aim of this case report is to discuss how to diagnose this syndrome and the management that had been done and further plans.","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123614664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hubungan Kadar Vitamin D Serum dengan Konsentrasi, Motilitas dan Morfologi Sperma pada Pria Subfertil di Klinik Teknologi Reproduksi Berbantu Aster Rumah Sakit Dr. Hasan Sadikin Bandung","authors":"Magnadi Yogi Rahma, Wiryawan Permadi, Anita Rachmawati, J. Effendi, Tono Djuwantono, Budi Handono","doi":"10.24198/OBGYNIA/V3N1.89","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N1.89","url":null,"abstract":"Tujuan : Untuk menganalisis hubungan kadar vitamin D dengan kualitas sperma pada pria subfertil, serta membandingkan kualitas sperma berdasarkan klasifikasi kadar vitamin D serum pada pria normospermia dan pria oligoasthenoteratospermia. Metode : Penelitian ini merupakan penelitian yang bersifat observasional analitik dengan rancangan studi potong lintang. Subjek penelitian adalah pria subfertil yang berusia 20-50 tahun, dibagi menjadi 2 kelompok, yaitu 30 pasien normospermia dan 16 pasien oligoasthenoteratospermia berdasarkan berdasarkan kriteria World Health Organization 2010. Penelitian dilakukan di Klinik Teknologi Reproduksi Berbantu Aster, RSUP Dr. Hasan Sadikin Bandung. Analisis data menggunakan analisis korelasi rank Spearman Hasil : Pada penelitian ini didapatkan korelasi positif antara kadar vitamin D dan motilitas sperma ( r = 0,639, p = 0,05). Perbedaan yang bermakna didapatkan antara kadar vitamin D pada kelompok normospermia dan oligoasthenoteratospermia dengan nilai p 0.05). There was a significant difference between vitamin D levels in normospermic and oligoasthenoteratospermia group with p <0,05. In the sperm quality comparison based on vitamin D serum classification, only sperm motility alone had a significant difference with the value of p <0.05. It was concluded that level of vitamin D serum has positive correlation with sperm motility. Key word : subfertile, vitamin D,  sperm quality","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132603687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gambaran Klinis dan Histopatologi Kasus-kasus Perdarahan Uterus Abnormal di Rumah Sakit Sumber Waras Jakarta","authors":"Andriana Kumala Dewi, Sony Sugiharto, Angelica Sunjaya, A. P. Sunjaya","doi":"10.24198/OBGYNIA/V3N1.185","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N1.185","url":null,"abstract":"Latar Belakang : Kasus perdarahan uterus abnormal (PUA) sering ditemui pada praktek sehari-hari. Prevalensi pada usia reproduktif adalah sekitar 10-30% dan merupakan sebab sekitar 25% dari semua tindakan bedah di bidang ginekologi. Penelitian ini bertujuan untuk menemukan gambaran klinis serta gambaran hasil histopatologi apa saja yang sering ditemukan pada pasien dengan diagnosis PUA. Metode : Penelitian ini adalah deskriptif cross sectional dengan data rekam medis. Data berasal dari pasien yang didiagnosis menderita PUA dan dilakukan tatalaksana operatif selama periode Januari sampai Desember 2018 dari RS Sumber Waras. Hasil :  Diperoleh 87 pasien dengan PUA yang menjalani tindakan operatif dan dilakukan pemeriksaan histopatologi selama periode penelitian. Perdarahan menstruasi yang tidak teratur dan dengan volume banyak menjadi keluhan paling sering ditemukan  (37,8% dan 34,5%). Sedangkan, berdasar hasil gambaran histopatologi yang didapat, ditemukan pada mayoritas pasien ditemukan gambaran patologi struktural (PALM) yaitu 86,2%. Kesimpulan : Berdasarkan klasifikasi PALM COEIN, kelainan struktural ditemukan sebagai penyebab utama PUA berdasar gambaran histopatologis. Clinical and Histopathologic Profile of  Patients with Abnormal Uterine Bleeding in Sumber Waras Hospital Jakarta Abstract Background : Abnormal uterine bleeding is a frequent presenting symptom in everyday practice. It has a prevalence of 10-30% in the reproductive age group and contributes to about 25% of all gynecologic surgical interventions. This study aims to ascertain the etiologies of patients diagnosed with abnormal uterine bleeding based on their clinical and histopathologic profile. Method : This is a descriptive cross-sectional study based on medical records. Data was obtained from patients diagnosed with AUB with an operative intervention between January and December 2018 in Sumber Waras Hospital. Result : There were 87 patients diagnosed with AUB who had undergone operative intervention and histopathologic testing during the study period. Irregular menstrual bleeding and heavy menstrual bleeding is the most common presenting symptom (37.8% and 34.5% respectively). Based on the histopathology results, structural causes of AUB (PALM) was found in most patients (86.2%). Conclusion: Based on the PALM COEIN classification, structural causes were found to be the main etiology of AUB based on histopathologic diagnosis. Key words : Abnormal uterine bleeding, PALM COEIN, leiomyoma, adenomyosis","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"224 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127897488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Obesity Increases Risk for Adverse Maternal Outcome at RSUP Dr. Mohammad Hoesin Palembang","authors":"Syifa Alkaf, Optima Fitra Ilhami, M. Azhar, Nuswil Bernolian, Ardesy Melizah","doi":"10.24198/obgynia/v3n1.178","DOIUrl":"https://doi.org/10.24198/obgynia/v3n1.178","url":null,"abstract":"Objective : To find the relationship between level of obesity and adverse maternal outcomes in pregnant women Method : An observational analytic study with a cross sectional design with secondary data from medical record. Subjects were pregnant women who gave birth at RSUP Dr. Mohammad Hoesin Palembang in January 2015-December 2017. Samples were taken by purposive sampling technique. BMIs  were divided into 5 categories based on WHO criteria, normoweight, overweight, obese level I, II, and III. Underweight was excluded from the study. Result : Of 252 research subjects, 94 (37.3%) were subjects with normal BMI, 102 (40.5%) were overweight, 44 (17.5%) were obese level I, 6 (2.4%) were level II, and 6 (2.4%) were level III. The maternal outcome consisted of 135 cases (53.6%) of preeclampsia, 6 cases of gestational diabetes mellitus (2.4%), 41 cases of uterine inertia (16.3%), 56 cases of preterm labor (22.2%), assisted delivery 111 cases (44%), and healthcare associated infections (HAIs) 6 cases (2.4%). Further analysis showed that increased level of maternal obesity is related significantly with preeclampsia, gestational diabetes mellitus, uterine inertia, and assisted delivery. Conclusion : There are statistically significant association between obesity level and the incidence of preeclamsia, gestational diabetes, uterine inertia and assisted delivery. Obesitas Pada Wanita Hamil Meningkatkan Morbiditas Maternal Di RSUP Dr. Mohammad Hoesin Palembang Abstrak Tujuan : Untuk menemukan hubungan antara tingkat obesitas dengan luaran maternal pada wanita hamil. Metode : Studi analitik observasional dengan desain potong lintang menggunakan data sekunder rekam medis. Subjek adalah wanita hamil yang melahirkan di RSUP Dr.Mohammad Hoesin Palembang pada Januari 2015 - Desember 2017. Sampel diambil secara purposive sampling. Indeks massa tubuh (IMT) dibagi menjadi 5 sesuai kriteria WHO, yaitu normal, berat badan lebih, obesitas level I, II, dan III. Berat badan kurang diekslusi dari penelitian. Hasil : Subjek penelitian dari 252 orang, 94 (37.3%) subjek dengan IMT normal, 102 (40.5%) subjek berat badan berlebih,  44 (17.5%) obesitas level I,  6 (2.4%) obesitas level II, dan 6 (2.4%) obesitas level III. Luaran  maternal terdiri dari 135 kasus (53.6%) of preeklampsia, 6 kasus diabetes mellitus gestasional,  41 kasus inertia uteri  (16.3%), 56 kasus persalinan preterm (22.2%), 111 kasus (44%) persalinan pervaginam berbantu, dan infeksi luka 6 kasus (2.4%).  Analisis menunjukkan adanya tingkatan obesitas maternal berkaitan secara signifikan dengan kejadian preeklampsia, diabetes mellitus gestasional, inertia uteri, dan persalinan pervaginam berbantu. Kesimpulan: Terdapat hubungan antara tingkat obesitas pada ibu hamil dengan preeklampsia, diabetes mellitus gestasional, dan persalinan pervaginam berbantu. Kata kunci : Indeks Massa Tubuh, Obesitas, Luaran Maternal, Morbiditas.","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130395606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primigravida Hamil 12 Minggu dengan Atrial Septal Defect Secundum dan Hipertensi Pulmonal Berat Janin Tunggal Hidup Intrauterin","authors":"C. Kesty, Nuswil Bernolian, Kgs Irawan Satria Arjanggi","doi":"10.24198/obgynia.v2n2s.150","DOIUrl":"https://doi.org/10.24198/obgynia.v2n2s.150","url":null,"abstract":"Latar Belakang : Atrial Septal Defect (ASD) apabila disertai hipertensi pulmonal berat harus dikonseling karena tingginya insiden morbiditas dan mortalitas ibu dan janin. Tujuan : Memaparkan sebuah kasus primigravida dengan ASD secundum dan hipertensi pulmonal berat sehingga dapat dilakukan tatalaksana dan pemilihan kontrasepsi yang sesuai. Metode : Laporan kasus seorang wanita berusia 30 tahun, hamil 12 minggu, mengeluh sesak nafas, batuk pada malam hari, dan jantung berdebar-debar. Hasil rontgen thoraks menunjukkan gambaran hipertensi pulmonal disertai peningkatan vaskularisasi paru. Kateterisasi jantung menunjukkan ASD secundum besar, hipertensi pulmonal berat, high flow, high resistance, dan reaktif dengan tes O2. Hasil ekokardiografi (2017) menunjukkan ASD secundum berat, regurgitasi trikuspid dan pulmonal moderat. Ultrasonografi abdomen menunjukkan kesan hamil 12 minggu janin tunggal hidup intrauterin, mioma uteri intramural dan subserosum, perdarahan subamnion dan subkorion. Pada pasien ini, dilakukan abortus provokatus medisinalis melalui pemberian Prostaglandin dilanjutkan dengan dilatasi dan kuretase. Kesimpulan : Kehamilan pada wanita dengan ASD umumnya ditoleransi dengan baik, dengan luaran ibu dan janin yang baik. Pasien dengan penyakit jantung berat sebaiknya tidak hamil dan bila hamil sebaiknya diterminasi. Preparat estrogen merupakan kontraindikasi pada pasien jantung. Pemilihan kontrasepsi harus mempertimbangkan keparahan, tipe anatomis kelainan jantung, dan keinginan ibu untuk mempertahankan fungsi reproduksinya. Kata Kunci : primigravida, ASD secundum, hipertensi pulmonal Abstract Background : Atrial Septal Defect (ASD) with severe pulmonary hypertension should be counseled because of the high incidence of maternal and fetal morbidity and mortality. Objective : Describing a case of primigravida with ASD secundum and severe pulmonary hypertension so that appropriate management and contraception can be selected. Method: A 30-year-old woman, 12 weeks pregnant, suffered from shortness of breath, coughing at night, and palpitations. Chest X-ray showed pulmonary hypertension with increased pulmonary vascularity. Cardiac catheterization showed a large ASD secundum, severe pulmonary hypertension, high flow, high resistance, and reactive O2 test. Echocardiography (2017) showed severe ASD secundum, moderate tricuspid, and pulmonary regurgitation. Abdominal ultrasonography showed 12 weeks gestational age single live fetus intrauterine, intramural and subserosal uterine myoma, and also subamniotic and subchorionic bleeding. We did provoked abortion using Prostaglandin continued with dilatation and curettage. Conclusion : Pregnancy in women with ASD is generally well tolerated, with good maternal and fetal outcomes. Patients suffered from severe heart disease should not be pregnant, and if necessary get pregnancy terminated. Estrogen preparations are contraindicated in these patients. The choice of contraception must consider the severity, ","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125865342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teratoma Sakrokoksigeus: Kelainan Kongenital yang dapat Dikoreksi","authors":"Arsyi Adliah Anwar, Efendi Lukas","doi":"10.24198/obgynia.v2n2s.142","DOIUrl":"https://doi.org/10.24198/obgynia.v2n2s.142","url":null,"abstract":"Latar Belakang : Teratoma sakrokoksigeus (SCT) adalah jenis tumor sel germinal yang terjadi terutama pada bayi dan anak-anak. Insidennya adalah satu dari 40.000 kelahiran hidup. Teratoma sakrokoksigeus yang terdeteksi prenatal harus menjadi perhatian dan memerlukan pemantauan ketat. Kasus : Seorang wanita 23 tahun terdeteksi memiliki janin dengan teratoma sakrokoksigeus dengan diagnosis banding meningomielokel pada usia kehamilan 34 minggu. Pasien ini tidak melakukan kunjungan antenatal yang teratur. Terminasi kehamilan dilakukan dengan seksio sesarea. Prosedur operatif dilakukan dua bulan setelah kelahiran. Kesimpulan : Teratoma sakrokoksigeus yang terdiagnosis prenatal dapat menyebabkan komplikasi yang berat pada janin, meskipun tidak terjadi pada kasus ini. Kunjungan prenatal yang teratur diperlukan untuk memantau ukuran massa. Mielomeningokel adalah salah satu diagnosis banding pada teratoma sakrokoksigeus tipe A. Proses terminasi kehamilan dapat menyebakan trauma pada jaringan tumor. Oleh karena itu, pilihan terminasi harus mempertimbangkan ukuran tumor. Kata kunci : Teratoma Sakrokoksigeus, Anomali Kongenital Abstract Background : Sacrococcygeal teratomas (SCT) is a subset of germ cell tumours occur predominantly in infants and children. The incidence is one in 40 000 live births. Sacrococcygeal teratomas diagnosed prenatally should be a caution and need regular observation. Case : A 23 years old woman was detected having a fetus with sacrococcygeal teratoma with differential diagnosis as a myelomeningocele at 34 weeks of pregnancy. The patient didn’t do prenatal visit regularly. The pregnancy was terminated with cesarean section without any complication. Surgical procedure of the tumor was succesfully done 2 months after delivery. Conclusion : Sacrococcygeal teratoma diagnosed prenatally can cause severe complication for the fetus, although it was not occur in this case.. Regular prenatal visit is needed to observe the size of the mass. Myelomeningocele is one of the differential diagnose in type A sacrococcygeal teratoma. The process of delivery can cause trauma to the tumor. In order that, termination method should be based on the size of the tumor. Key words : Sacrococcygeal Teratoma, Congenital Anomaly","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128776140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and Management of Heterotopic Pregnancy: A Case Report","authors":"Harnovin Kuanda, Muhamad Husen Ali, Rommy Andika Kurniawan","doi":"10.24198/obgynia.v2n2s.171","DOIUrl":"https://doi.org/10.24198/obgynia.v2n2s.171","url":null,"abstract":"Background : Heterotopic pregnancy is a rare case of pregnancy. The incident is estimated to be 1:30000 to spontaneus pregnancy. Heterotopic pregnancy is a life threatening condition to maternal and intrauterine fetus. Case Report :A 36 years old woman came with over 1 month history of amenorrhea, after being examined, her gestational age was 9-10 weeks. On 28th February 2018 patient came to PHC due to lower abdominal pain and vaginal bleeding. Ectopic pregnancy was revealed then laparotomy was performed. Then, patient came back and complained of enlarged abdomen since the laparotomy, ultrasonography examination showed intrauterine fetus. At 35 weeks gestational age, patient was undergoing cesarean section due to fetal distress. Discussion :Heterotopic pregnancy are both intrauterine and ectopic pregnancy that occur at the same time. Heterotopic pregnancy often hardly detect because of unspecific symptoms. In this case it also found difficulty in diagnosing heterotopic pregnancy, the patient was only diagnosed as ruptured ectopic pregnancy. Conclusion :Heterotopic pregnancy has a high mortality rate if the diagnosis and treatment is not done well. Ultrasonography (USG) examination has an important role in order to help diagnosing in remote area. Key words : Heterotopic pregnancy, USG, Diagnose, Treatment Abstrak Latar belakang :Kehamilan Heterotopik adalah kehamilan yang sangat jarang terjadi, angka kejadiannya sekitar 1:30000 dibandingkan dengan kehamilan spontan. Kehamilan Heterotopik seringkali menyebabkan komplikasi yang dapat mengancam jiwa ibu dan janin. Laporan Kasus :Wanita usia 36 tahun datang dengan keluhan Amenorea lebih dari 1 bulan, setelah di periksa pasien dinyatakan hamil dengan usia kehamilan 9-10 minggu. Pada 28 februari 2018, pasien datang ke puskesmas dengan keluhan nyeri perut bawah dan keluar darah dari jalan lahir, kemudian pasien di rujuk ke Rumah Sakit. Pasien didiagnosis dengan kehamilan ektopik dan dilakukan laparotomi. Kemudian pasien  kontrol dan mengeluh perut bertambah besar pascaoperasi, dari pemeriksaan ultrasonographi didapatkan adanya janin intrauterin. Pada usia kehamilan 35 minggu dilakukan operasi caesar dikarenakan gawat janin. Diskusi:Kehamilan Heterotopik adalah kehamilan intrauterin dan kehamilan ektopik yang terjadi pada waktu yang bersamaan. Kehamilan heterotopik seringkali sulit dideteksi dikarenakan gejala yang tidak spesifik. Pada kasus ini juga ditemukan kesulitan dalam mendiagnosa kehamilan heterotopik. Kesimpulan :Kehamilan heterotopik memiliki angka mortalitas yang tinggi jika diagnosis dan tatalaksana yang dilakukan tidak baik. USG berperan penting dalam membantu penegakkan diagnosis di daerah terpencil. Kata kunci : Kehamilan Heterotopik; USG; Diagnosis; Tatalaksana","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126699652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Multi-Drug-Resistant Tuberculosis with Unilateral Destroyed Lung in Pregnancy: A Case Report","authors":"I. Febriana, Sayogo Atikah, S. Pudyastuti","doi":"10.24198/obgynia.v2n2s","DOIUrl":"https://doi.org/10.24198/obgynia.v2n2s","url":null,"abstract":"Background : Multi-drug-resistant Tuberculosis (MDR-TB) remains a public health problem in developing countries such as Indonesia. The extensive parenchymal damage due to MDR-TB could manifest as an irreversible destroyed lung, leading to respiratory and  also cardiovascular complication. Its occurrence in pregnancy is uncommon but is highly associated with higher mortality and morbidity for both maternal and fetal. Case Report : We report a case of 24 year old primigravida in National Respiratory Center Hospital, diagnosed with  an unilateral destroyed lung due to MDR-TB in pregnancy at 32 weeks of gestational age. On initial presentation, she reported fatigue, nausea, night sweats, chronic dyspnoe and was found to have complete left destroyed lung. Her disease was managed during pregnancy using long-term oxygen therapy despite persistent desaturation. Conlusion : Aside from frequent monitoring, prolonged oxygen therapy might benefit the chronic hypoxia condition in gestational destroyed lung due to previous MDR-TB infection, for preventing maternal-fetal mortality and morbidities, such as respiratory failure and IUGR. Abstrak Latar Belakang : Tuberkulosis Multi-drug-resistant (TB-MDR) tetap menjadi masalah kesehatan pada negara berkembang, seperti Indonesia. Kerusakan parenkin luas yang diakibatkan oleh infeksi TB-MDR dapat bermanifestasi sebagai kerusakan paru ireversibel, dengan komplikasi respiratorik dan kardiovaskular. Kejadian kerusakan paru akibat TB-MDR dalam kehamilan jarang terjadi, namun berdampak pada peningkatan mortalitas dan morbiditas pada janin dan ibu. Laporan Kasus : Studi ini melaporkan kasus perempuan primigravida 24 tahun didiagnosa dengan kerusakan paru unilateral akibat infeksi TB-MDR pada kehamilan 32 minggu di RS Pusat Paru Nasional. Pada pemeriksaan awal, didapatkan pasien mengeluhkan kelelahan kronik, nausea, keringat malam, sesak kronik dan didapatkan memiliki kerusakan paru kiri komplit. Keadaan pasien dalam kehamilan ditatalaksana dengan terapi oksigen jangka panjang untuk mengatasi desaturasi persisten Kesimpulan : Di samping pengawasan ketat, terapi oksigen jangka panjang dapat menjadi tatalaksana utama untuk kondisi hipoksia kronik pada kerusakan paru dalam kehamilan akibat infeksi lama TB-MDR untuk mencegah morbiditas dan mortalitas ibu dan janin, seperti gagal napas dan pertumbuhan janin terhambat  (PJT).","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126481703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}