Indonesian Journal of Obstetrics & Gynecology Science最新文献

{"title":"Faktor Risiko Kejadian Tumor Trofoblas Gestasional Pasca Evakuasi Molahidatidosa di RSUP Dr. Hasan Sadikin Bandung Periode Agustus 2013 – Agustus 2018","authors":"Indah Permata Noer Islami, Dodi Suardi, Hanom Husni Syam, M. A. Ritonga","doi":"10.24198/OBGYNIA/V3N2.201","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N2.201","url":null,"abstract":"Tujuan : Penelitian bertujuan mengetahui faktor risiko kejadian TTG pasca evakuasi, untuk memprediksi penderita molahidatidosa yang berkembang menjadi TTG atau kembali normal. Metode : Menggunakan studi case control retrospektif dalam waktu 1 Agustus 2013 - 1 Agustus 2018. Populasi penelitian, penderita molahidatidosa yang datang dan dirawat pada Obstetri dan Ginekologi RSUP Hasan Sadikin. Hasil : Terdapat 59 pasien high risk, dan 67 pasien low risk. Probabilitas <0,05 terdapat hubungan signifikan antara usia dengan kejadian TTG. Probabilitas 0,031, terdapat hubungan signifikan antara paritas dengan kejadian TTG. Dengan uji Fisher Exact terdapat hubungan bermakna antara kadar βHCG praevakuasi dengan kejadian TTG (p value =<0,001), dan hubungan bermakna antara gambaran PA dengan kejadian TTG (p value =<0,001). Dengan uji Spearman Correlation terdapat hubungan yang bermakna antara kadar βHCG Praevakuasi dengan gambaran PA (p value <0, 001). Kesimpulan : Terdapat hubungan yang bermakna antara usia, paritas, BHCG, Patologi Anatomi, dengan kejadian TTG pasca evakuasi molahidatidosa. Dari analisis multivariat dengan uji regresi logistic didapatkan bahwa BHCG dan PA yang merupakan faktor risiko TTG. Risk Factors Trofoblas Tumor of Post Evacuation Of Hydatidiform Mole in Dr. Hasan Sadikin General Hospital Bandung Period August 2013−August 2018 Period Abstract Objective : This study aims to determine the risk factors for GTT events after HM evacuation, used to predict patients who will develop into GTT or return to normal. Methods : Case control study (retrospective) was conducted from August 1st 2013 −August 1st 2018. Population of this study was all patients with HM who came and treated at the RSHS Obstetrics and Gynecology Department. Result : There are 59 high risk, 67 low risk patients. The probability value is 0.015, (<0.05) there is a significant relation between age and the incidence of GTT. The probability value of 0.031, there is a significant relationship between parity and the incidence of GTT. Fisher Exact test, significant relation between pre-evacuated βHCG levels and GTT events (p value = <0,001), and significant relation between Pathology Anatomy result and GTT events (p value =<0,001) was found. Spearman Correlation test, there was significant relation between levels of βHCG pre-evacuation with Pathology Anatomy result (p value <0, 001). Conclusion : There is a significant relation between age, parity, BHCG, Pathology Anatomic result, and the incidence of GTT after evacuation of HM. From multivariate analysis with logistic regression test, it was found that BHCG and pathology anatomic were risk factors for GTT. Key words : Molahidatidosa, Gestational Trophoblast Tumor.","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130787543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Luaran Kehamilan pada Pasien dengan Infertilitas Berkaitan dengan Endometriosis, Infertilitas karena Faktor Tuba, dan Unexplained Infertility, setelah Menjalani Prosedur IVF / ICSI di Klinik Aster RSUP Dr. Hasan Sadikin Bandung","authors":"D. Wulandari, Budi Handono, Anita Rachmawati, D. Hidayat","doi":"10.24198/OBGYNIA/V3N2.206","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N2.206","url":null,"abstract":"Tujuan : Penelitian ini bertujuan untuk mengetahui dan membandingkan luaran kehamilan dari setiap penyebab infertilitas pada pasien yang dilakukan teknologi reproduksi berbantu. Metode : Penelitian ini merupakan penelitian analisis komparatif yang dilakukan secara longitudinal retrospektif. Data didapatkan dari rekam medik pasien dengan infertilitas terkait endometriosis, faktor tuba, dan unexplained infertility, setelah menjalani prosedur in vitro fertilization dan intra cytoplasmic sperm injection pada  Januari 2013− Desember 2018. Luaran yang dinilai pada penelitian ini adalah kehamilan, abortus, dan kehamilan ektopik. Hasil : Sebanyak 94 pasien menjadi subjek penelitian ini. Infertilitas karena faktor tuba menjadi penyebab infertilitas terbanyak (74,5%) dan unexplained infertility menjadi penyebab terjarang (8,5%).  Intra cytoplasmic sperm injection merupakan metode reproduksi berbantu yang paling sering dilakukan (78,7%). Luaran kehamilan dengan persalinan terjadi pada 65 subjek (69,1%) sementara sisanya abortus. Tidak terdapat kejadian kehamilan ektopik. Tidak terdapat perbedaan bermakna dalam luaran kehamilan berdasarkan penyebab infertilitasnya (p=0,21). Kesimpulan : Tidak terdapat perbedaan luaran kehamilan baik partus ataupun abortus pada pasien yang dilakukan teknologi reproduksi berbantu berdasarkan penyebab infertilitasnya. Pregnancy Outcomes in Patients with Infertility Related to Endometriosis, Infertility due to Tubal Factors, and Unexplained Infertility, After Undergoing IVF/ICSI Procedures in Aster Clinic General Hospital Dr. Hasan Sadikin Bandung Abstract Objective : This study was aimed to describe and compare the pregnancy outcomes in each cause of infertility on patients who get assisted-reproduction technology procedure. Method : This was an analytic comparative study, that conducted longitudinal-retrospectively. The data were obtained from medical records of patients with endometriosis associated infertility, tubal factors associated infertility, and unexplained infertility after got either in vitro fertilization or intra cytoplasmic sperm injection procedure from January 2013–December 2018. The pregnancy outcomes consisted of delivery, abortion, or ectopic pregnancy. Result : A total of 94 patients were enrolled in this study. Tubal factors was the commonest cause of infertility (74.5%) and unexplained infertility was the most rarely cause of infertility (8.5%). Intra cytoplasmic sperm injection was the most frequent procedures (78.7%). Labor were  occurred in 65 subjects (69.1%) and the remains aborted.  Ectopic pregnancy was not occurred. There was no significant difference in pregnancy outcomes according the causes of infertility. (p=0,21). Conclusion : Pregnancy outcomes, both labor and abortion, were not different based on the cause of infertility among patients who get assisted-reproduction technology procedure. Key words : assisted-reproduction technology, in vitro fertilization, infertility, intra cytoplasmic sper","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116293654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"C-Reactive Protein Concentration in Very Early, Early and Late Preterm Labour","authors":"T. H. Madjid, Rose Dita Prasetyawati, Nathania Nathania, Wulan Ardhana Iswari, M. Aziz, Dini Pusianawati, J. Effendi","doi":"10.24198/OBGYNIA/V3N2.199","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N2.199","url":null,"abstract":"Objective : Preterm labor (PTL) is related to neonatal morbidity and mortality. The etiology of PTL is multifactorial, however maternal inflammation is suspected to play a large role. Research has indicated a relationship between the increase of C-reactive protein (CRP), a biomarker of general tissue inflammation to the incidence of preterm labor. This study aimed at examining the relationship between preterm labor and CRP levels. Method : This was a case-control retrospective study.  Cases were patients presenting with preterm labor who came to the Department of Obstetrics and Gynecology of Hasan Sadikin Hospital Bandung. Patients were classified into very early preterm, early preterm, late preterm; control group was taken from patients without delivery complication (n=20/group).  CRP serum was examined using immunoassay method. Result : CRP median value in the early preterm group was greater than very early preterm, early preterm, and control (8.15 mg/L vs 6.5 mg/L vs 5.6 mg/L vs 5.75 mg/L, respectively) but statistical significance was not achieved (p> 0.05). Further comparisons between the very early, early preterm vs control and late preterm vs control groups were performed and no statistical significance was found. Conclusion : Further research is required to investigate the link between maternal CRP and preterm labor. Konsentrat Protein C-Reaktif (PCR) pada Persalinan Prematur Sangat Awal, Awal, dan Terlambat Abstrak Tujuan : Persalinan prematur memiliki kaitan yang erat dengan morbiditas dan mortalitas neonatus. Etiologi persalinan prematur ini dipengaruhi oleh multifaktor. Namun, inflamasi maternal menjadi salah satu faktor yang dicurigai paling mempengaruhi. Beberapa penelitian melihat adanya hubungan antara peningkatan Protein C-Reaktif (PCR), biomarker untuk inflamasi jaringan secara umum, dengan insidensi persalinan prematur. Penelitian ini bertujuan untuk melihat relasi antara kadar PCR dengan kejadian persalinan prematur. Metode : Penelitian ini menggunakan metode kasus kontrol (case control). Kasus berasal dari pasien dengan persalinan prematur yang datang ke Departemen Obstetri dan Ginekologi RS Dr. Hasan Sadikin Bandung. Pasien dikelompokkan menjadi 3 kategori, yaitu persalinan prematur sangat awal, awal, dan terlambat. Kelompok kontrol diambil dari pasien yang menjalani persalinan tanpa komplikasi (n=20/kelompok). Serum PCR dianalisa menggunakan metode uji imunoserologi (immunoassay). Hasil : Nilai median PCR pada kelompok prematur awal lebih besar daripada kelompok prematur sangat awal, awal, dan kontrol (secara berurutan, 8.15 mg/L vs 6.5 mg/L vs 5.6 mg/L vs 5.75 mg/L), namun tidak signifikan secara statistik (p>0,05). Perbandingan lebih lanjut antara prematur sangat awal, awal, dengan kelompok kontrol serta prematur terlambat dengan kelompok kontrol dilakukan dan tidak signifikan secara statistik. Kesimpulan : Penelitian lebih lanjut dibutuhkan untuk melihat hubungan antara kadar PCR maternal dengan persalinan prematur. Kata","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117307295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hubungan Kualitas Hidup dan Kebutuhan Perawatan Paliatif Pasien Kanker Ginekologi di Rumah Sakit Dr. Hasan Sadikin","authors":"R. T. Rumanti, Akhmad Yogi Pramatirta, Ali Budi Harsono, J. Effendi","doi":"10.24198/OBGYNIA/V3N2.218","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N2.218","url":null,"abstract":"Tujuan : Tujuan penelitian ini adalah untuk mengetahui bagaimana hubungan kualitas hidup dan kebutuhan perawatan paliatif pada pasien kanker ginekologi.      Metode : Subjek penelitian ini adalah seluruh pasien kanker ginekologi yang dirawat di Rumah Sakit Dr. Hasan Sadikin Bandung pada bulan November-Desember 2018. Penelitian ini merupakan studi analitik dengan rancangan cross sectional. Data yang diperoleh dianalisis secara bivariat dengan menggunakan chi square dengan α = 0,05, untuk mengetahui hubungan antara kualitas hidup dengan kebutuhan perawatan paliatif. Hasil : Karakteristik subjek terbanyak berusia > 50 tahun (65,67%), pendidikan dasar (70,15%), ibu rumah tangga (89,55%), pendapatan di atas upah minimum regional (61,19 %), tujuan rawat inap kemoterapi (47,76%) dan tipe kanker karsinoma serviks (43,28%). Subjek penelitian dengan skor paliatif ≥ 4 sebanyak 25 orang (37,31%). Keluhan yang terbanyak adalah berat badan turun dan tidak nafsu makan (86,57 %). Kualitas hidup pasien kategori baik sebanyak 29 orang, sedang 36 orang, dan kurang 2 orang. Kualitas hidup pasien kanker ginekologi berhubungan dengan kebutuhan perawatan paliatif dengan nilai signifikansi p 0,004. Simpulan : Kualitas hidup berhubungan dengan skor paliatif. Semakin rendah skor paliatif maka kualitas hidup semakin baik. Relations of  Quality of Life and Characteristics of Gynecological Cancer Patients In Hasan Sadikin Hospital Abstract Objective : The purpose of this study was to determine the characteristics of gynecological cancer patients, determine the quality of life of all gynecological cancer patients and to asses the correlation of quality of life and palliative care needs in gynecological cancer patients. Method : The subjects of this study were all gynecological cancer patients who were treated at Dr. Hasan Sadikin Hospital Bandung in November-December 2018. This study was an analytic study with a cross sectional design. Data obtained from the study were analyzed bivariately using chi square with α = 0.05, to determine the relationship between quality of life and palliative care needs. Results : The most characteristics of the subjects were with age> 50 years (65.67%), primary education (70.15%), housewives (89.55%) with income above the regional minimum wage (61.19%), the main goal of hospitalization is chemotherapy (47.76%) and the most types of cancer are cervical carcinoma (43.28%). The research subjects who had a palliative score of ≥ 4 were 25 people (37.31%). The most complaints were weight loss and no appetite (86.57%). The quality of life of patients with good category was 29 people, medium category was 36 people and poor category was 2 people. The quality of life of gynecological cancer patients has correlation with palliative care needs with a significance value of p 0.004. Conclusion : Quality of life has correlation with palliative scores, the lower the palliative score, the better the quality of life. Key words : Gynecological cancer; quality of l","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124616902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pengaruh Vaksin BCG dalam Meningkatkan Proses Segresi Seluler pada Lesi Prakanker Serviks Uteri Derajat Rendah","authors":"Yudi Mulyana Hidayat, Putu Giri Saputro, Dodi Suardi, Gatot N. A. Winarno, Siti Salima, Ali Budi Harsono","doi":"10.24198/OBGYNIA/V3N2.82","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N2.82","url":null,"abstract":"Tujuan : Penelitian ini adalah untuk menganalisis peranan pemberian vaksin bacille calmette-guerin (BCG) terhadap proses regresi seluler pada lesi prakanker serviks uteri derajat rendah Metode : Penelitian ini merupakan penelitian eksperimental dengan rancangan pretest (IVA dan Histopatologi) - posttest (IVA dan Test HPV DNA) with control design di Poliklinik Rumah Sakit Dr. Hasan Sadikin Bandung pada bulan Desember 2017-Maret 2018. Hasil : Untuk pemeriksaan IVA bulan ke-0 pada kelompok BCG kategori positif sebanyak 9 (100.0%) sedangkan untuk pemeriksaan IVA bulan ke-3 pada kelompok BCG kategori positif sebanyak 3 (33.3%) dan negatif menjadi sebanyak 6 (66.7%), pemeriksaan tes HPV DNA bulan ke 12 pada kelompok BCG kategori positif HPV DNA High Risk tidak ditemukan ( 0 % ). Hasil uji statistik pada kelompok perlakuan diperoleh nilai p 0.05. Kesimpulan : Terdapat peranan pemberian vaksin BCG terhadap regresi seluler lesi prakanker serviks derajat rendah. The effect of Bacille Calmette-Guerin vaccine on regression of cervical intraepithelial neoplasia-1 Abstract Objective : The aim of this study was to analyze the role of Baccile Calmete Guerin (BCG) vaccines delivery in low grade precancerous cervical lesions. Methods : The design of the study was a pretest and posttest experimental with control, done at Hasan Sadikin Hospital Bandung Outpatient Clinic during December 2017–March 2018. Result : Patients with positive VIA test in the intervention group in month-0 were 9 patients (100.0%), in month-3 were 3 patients (33.33%) and the other 6 patients (66.7%) changed into negative. Patients with positive VIA test in the control group in month-0 were 9 patients (100.0%), in month 3 were 8 patients (88.9%) and the other 1 patients (11.1%) changed into negative. The result of statistical analysis in the intervention group was p 0.05. Conclusion : : there is a role of BCG vaccine in low grade precancerous cervical lesions. Key words : BCG vaccine, VIA test, Low grade cervical precancerous lesions.","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"221 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132468132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perbandingan Uji Hemostasis pada Preeklamsia antara Awitan Dini pada Awitan Lambat","authors":"Aisah Djumadisstsaniah, Yusrawati Yusrawati, A. Friadi","doi":"10.24198/OBGYNIA/V3N1.183","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N1.183","url":null,"abstract":"Tujuan : Penelitian ini bertujuan untuk mengetahui perbandingan uji hemostasis pada preeklamsia antara awitan dini (PEAD) dengan awitan lambat (PEAL) Metode : Penelitian ini adalah penelitian analitik observasional dengan pendekatan potong lintang dengan menggunakan data rekam medis pasien preeklamsia yang dirawat dan atau melahirkan di RSUP DR M Djamil Padang. Analisis univariate disajikan dalam bentuk tabel distribusi frekuensi dan analisis univariate menggunakan uji T tidak berpasangan dan uji Mann-Whitney Hasil : PT (Prothrombine Time) dan APTT (Activated Partial Thromboplastin Time) lebih rendah pada PEAD daripada PEAL (p>0,05), D-dimer lebih tinggi PEAD daripada PEAL(p>0,05), dan jumlah trombosit lebih rendah PEAD daripada PEAL(p<0,05) Kesimpulan : Pada penelitian ini tidak terdapat perbedaan yang bermakna dari parameter faal pembekuan darah berupa PT, APTT, dan D-dimer, tetapi terdapat perbedaan yang bermakna pada jumlah trombosit antara PEAD dan PEAL dengan jumlah trombosit PEAD lebih rendah daripada PEAL Comparison of Hemostatic Test Result Between Cases of Early and Late Onset Preeclampsia Abstract Objective : This study aimed to compare haemostatic test of early onset preeclampsia and late onset preeclampsia Method : This study was observational analytic study using cross-sectional design that collected data from medical  records patients of preeclampsia who were hospitalized and/or giving birth in RSUP DR M Djamil Padang. Data were analized using Univariate analysis were presented in the form of frequency distribution table and Bivariate data were tested with Independent T-Test and Mann-Whitney Test Result : In this study, there was no differences in prothrombin time, activated partial thromboplastine time and D-dimer but thrombocyte count were different between early and late onset Preeclampsia Conclusion : On this research thrombocyte count is lower in early than late onset Preeclampsia and there is significantly different between early and late onset Preeclampsia Key words : prothrombin time, activated partial thromboplastin time, D-dimer, thrombocyte count, early and late onset  preeclampsia","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116900384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Karakteristik Klinis dan Laboratorium pada Pasien Preeklamsia Berat Awitan Dini dan Awitan Lanjut di RSUP Fatmawati Jakarta Tahun 2016-2017","authors":"Annissa Kallista Amyranti, Evalina Silalahi","doi":"10.24198/obgynia/v3n1.155","DOIUrl":"https://doi.org/10.24198/obgynia/v3n1.155","url":null,"abstract":"Tujuan : Preeklamsia adalah sebuah gangguan dan meliputi banyak organ, yang sampai saat ini masih menjadi penyebab kematian ibu tertinggi kedua di dunia dan di Indonesia. Peningkatan kadar asam urat sering ditemukan pada pasien preeklamsia. Diketahui penyebabnya adalah akibat penurunan fungsi ginjal, penurunan kerusakan jaringan, dan peningkatan kerja enzim xantin oksidase. Metode : Penelitian ini dilakukan dengan metode cross-sectional dari data rekam medis pasien preeklamsi berat di RSUP Fatmawati Jakarta. Hasil : Pasien preeklamsia berat di RSUP Fatmawati 60% diantaranya pada kelompok usia 20–35 tahun, dengan IMT ³ 30 sebanyak 42,4%, dan 68,5% pada pasien primi dan multi para. Analisis penelitian penggunakan uji hipotesis chi square, menunjukan terdapat hubungan antara kadar asam urat darah dengan perburukan preeklampsia berat (p=0,000<0,005). Kesimpulan : Terdapat hubungan antara kadar asam urat darah dengan awitan perburukan preeklamsia berat. Clinical and Laboratory Characteristics of Early and Late Onset Severe Preeclampsia Patients in Fatmawati General Hospital Jakarta 2016-2017 Abstract Objective : Preeclampsia is disorder that affects many organs, which until now is still the highest cause of maternal death in the world and in Indonesia. Increased uric acid levels are often found in preeclamsy patients. The causes are known to decrease kidney function, decrease tissue damage, and increase the work of the xanthine oxidase enzyme. Methods : This research was conducted by cross-sectional method by taking medical records of severe preeclampsia patients at Fatmawati General Hospital, Jakarta. Result : Patients with severe preeclampsia  in the Fatmawati General Hospital were 60% approved in the age group 20-35 years, with BMI ³ 30 as many as 42.4% , and 68,5% of them were primiparous and multiparous women. The analysis of the study used the chi square hypothesis test, showed that blood uric acid levels has a relationship on the onset of worsening severe preeclampsia  (p=0,000<0,005). Conclusion : This analysis showed that there was a relationship between blood uric acid levels and the onset of worsening severe preeclampsia . Key words : Severe preeclampsia , uric acid, early onset, late onset.","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"153 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132879053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategi Menurunkan Kematian Ibu Karena Preeklamsi dan Eklamsi","authors":"J. C. Mose","doi":"10.24198/OBGYNIA/V3N1.193","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N1.193","url":null,"abstract":"Tujuan : Menyimpulkan beberapa hasil penelitian tentang preeklamsi dan upaya menurunkan kematian ibu di negara maju maupun berkembang termasuk di Indonesia dan RSHS Bandung untuk menyusun strategi menurunkan kematian ibu karena preeklamsi. Metode : Dilakukan penelitian potong silang dengan rancangan observasional analitik dengan membandingkan data ibu hamil dengan preeklamsi/eklamsi yang melahirkan di RS Hasan sadikin Bandung periode Maret sampai September 2012 (sebelum JKN) dan 1 Januari 2016 sampai 31 Desember 2017(saat JKN dilaksanakan). Data dianalisis menggunakan uji statistik chi kuadrat untuk membandingkan perbedaan dengan kemaknaan nilai p 4, and evidence of hypertension and cardiac complications before and during the implementation of NHIP. Discussion : The strategies for reducing maternal mortality due to preeclampsia are as follows : supporting the government programs to overcome poverty, education and transportation; socializing signs and symptoms of preeclampsia to the community; early detection of risk factors, blood pressure measurement and urine protein followed by administration of low dose aspirin and calcium tablets for prevention; training on Doppler examination of uterine arteries for OBGYN specialist and socializing standard guidelines and protocol for the management of preeclampsia; and training for a ‘preeclampsia special team’ in referral hospitals. Key words : Preeclampsia, maternal mortality, strategy for reducing maternal mortality.","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122293319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Faktor Risiko Kejadian Hipertensi dalam Kehamilan di Rumah Sakit Bhayangkara Denpasar","authors":"Febyan Febyan, Ida Bagus Rumbawa Pemaron","doi":"10.24198/OBGYNIA/V3N1.177","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N1.177","url":null,"abstract":"Tujuan : Kejadian hipertensi dalam kehamilan dapat dipengaruhi oleh berbagai faktor, yaitu; Primigravida, nulliparitas, usia ibu ( 35 tahun), dan Indeks Massa Tubuh, yang merupakan bagian dari faktor risiko terjadinya penyakit hipertensi dalam kehamilan. Penelitian ini bertujuan untuk mengetahui faktor-faktor risiko yang berhubungan dengan hipertensi dalam kehamilan di departemen Obstetri dan Ginekologi Rumah Sakit Bhayangkara Denpasar, Periode Oktober – Desember 2018. Metode : Penelitian ini merupakan studi observasional dengan metode potong lintang, variabel yang digunakan berupa usia maternal, graviditas, indeks massa tubuh terhadap kejadian hipertensi dalam kehamilan. Sampel penelitian ini adalah ibu hamil yang datang ke Poli Rawat Jalan Departemen Obstetri dan Ginekologi Rumah Sakit Bhayangkara, Denpasar, pada bulan Oktober – Desember 2018. Sampel didapatkan dengan teknik total sampling, sebanyak 43 orang dari 531 ibu mengalami hipertensi dalam kehamilan. Hasil : Berdasarkan hasil penelitian ini, didapatkan bahwa tidak ada hubungan antara variabel graviditas dengan kejadian hipertensi dalam kehamilan (p=0,077), selanjutnya variabel indeks massa tubuh (OR = 2,602; p = 0,005) dan variabel usia maternal (OR=2,774; p =0,004) menunjukkan bahwa ada hubungan yang signifikan dengan kejadian hipertensi dalam kehamilan. Hasil analisis multivariate menunjukan bahwa, variabel usia maternal merupakan faktor risiko paling besar (p=0,003) terjadinya hipertensi dalam kehamilan. Simpulan : Terdapat hubungan antara indeks massa tubuh, dan usia maternal dengan kejadian hipertensi dalam kehamilan, dan tidak ada hubungan yang bermakna, antara graviditas dengan kejadian hipertensi dalam kehamilan. Abstract Objective : To review some risk factors of the recurrence of hypertension in pregnancy disorder. The incidence of hypertension in pregnancy can be affected by several factors: Primigravida, nulliparitas, maternal age and increased body mass index are the risk factors for hypertension in pregnancy. Methods : This study was an observational study with cross-sectional the variable used were maternal age, gravidity and body mass index (BMI) on the incidence of hypertension in pregnancy. The samples were pregnant women who came to Clinic of Obstetrics and Gynecology Departement, Bhayangkara Hospital Denpasar during October to December 2018. Statistical test used was chi square factor exact tes. Result : The most important risk factors for hypertension in pregnancy such as, body mass index (OR 2,60 95% CI 1,36-4,95 p = 0,005) and maternal age (OR 2,74 95% CI 1,41-5,43 p =0,004) mean while gravidity (OR 1,58 95% CI 0,70-3,57 p=0,077) is not a significant risk factor. Conclusion : There is a correlation between maternal age and body mass index with hypertension in pregnancy and  no correlation between gravidity with hypertension in pregnancy.","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121431250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kanker Ovarium : “The Silent Killer”","authors":"Ali Budi Harsono","doi":"10.24198/OBGYNIA/V3N1.192","DOIUrl":"https://doi.org/10.24198/OBGYNIA/V3N1.192","url":null,"abstract":"Tujuan artikel ini adalah untuk mereview sejarah dan implikasi kanker ovarium dengan bahasa metafora pembunuh diam-diam atau “ Silent Killer ” sehingga akan meningkatkan kesadaran tentang kanker ovarium. Pada abad kedua puluh, metafora pembunuh diam-diam sering dikaitkan dengan kata berbahaya yang menggambarkan kanker ovarium. Istilah \" silent killer \" sebetulnya sering digunakan untuk menggambarkan kanker lain dan juga diterapkan pada penyakit seperti hipertensi dan diabetes. Kanker ovarium sering disebut sebagai pembunuh diam-diam karena diyakini sebagian besar pasien didiagnosis pada stadium lanjut dan sering tidak ditemukan gejala yang jelas pada stadium awal","PeriodicalId":210732,"journal":{"name":"Indonesian Journal of Obstetrics & Gynecology Science","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122784591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}