Resuscitation最新文献

{"title":"Transoesophageal echocardiography during cardiopulmonary resuscitation for cardiac arrest: A scoping review","authors":"Tommaso Scquizzato, Carolyn M. Zelop, David Purkarthofer, Anna Mara Scandroglio, Natalie Kruit, Richard McGowan, Felipe Teran, Katherine Berg, Ari Moskowitz, Ian R. Drennan, Anders Aneman, Bernd Böttiger, Keith Couper, Conor Crowley, Sonia D’Arrigo, Charles Deakin, Shannon Fernando, Brian Grunau, Asger Granfeldt, Karen Hirsch, Mathias Johan Holmberg, Peter Kudenchuk, Eric Lavonas, Carrie Leong, Robert Neumar, Nikolaos Nikolaou, Jerry Nolan, Brian O’Neil, Helen Pocock, Claudio Sandroni, Jasmeet Soar, Markus Skrifvars, Tonia Nicholson, Neville Vlok, Michelle Welsford, Chia Yew Woon, Jaylen Wright","doi":"10.1016/j.resuscitation.2026.111261","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2026.111261","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"25 1","pages":"111261"},"PeriodicalIF":6.5,"publicationDate":"2026-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148755077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: outcomes and clinical trajectories","authors":"Giacomo Veronese, Lorenzo Grazioli, Paolo Meani, Oliviero Fochi, Francesco Fazzi, Alfio Bronco, Giovanna Colombo, Maddalena Serafini, Alessandra Salurso, Isabella Pellicioli, Floriana Ferrari, Sergio Vedovati, Oliviero Francesco Valoti, Davide Ghitti, Silvia Viscardi, Enrico Ammirati, Francesco Seddio, Nicola Uricchio, Daniele Bonacina, Camilla Volpi, Francesca Raimondi, Ezio Bonanomi, Roberto Lorusso, Ferdinando Luca Lorini","doi":"10.1016/j.resuscitation.2026.111263","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2026.111263","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"39 1","pages":"111263"},"PeriodicalIF":6.5,"publicationDate":"2026-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148755078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric out-of-hospital cardiac arrest occurring before and after emergency medical service arrival: a retrospective study","authors":"Charlotte Kennedy, Emily Nehme, Tegwyn McManamny, David Anderson, Ashanti Dantanarayana, Ziad Nehme","doi":"10.1016/j.resuscitation.2026.111267","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2026.111267","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"22 1","pages":"111267"},"PeriodicalIF":6.5,"publicationDate":"2026-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148755079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric out-of-hospital cardiac arrest occurring before and after emergency medical service arrival: a retrospective study.","authors":"Charlotte Kennedy, Emily Nehme, Tegwyn McManamny, David Anderson, Ashanti Dantanarayana, Ziad Nehme","doi":"10.1016/j.resuscitation.2026.111267","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2026.111267","url":null,"abstract":"<p><strong>Aim: </strong>To examine the association between witness status and the incidence, characteristics, and survival outcomes of paediatric out-of-hospital cardiac arrest (OHCA) attended by emergency medical services (EMS).</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of paediatric (<18 years) OHCA cases attended by EMS between 1 January 2000 and 31 December 2024. Cases were identified from the Victorian Ambulance Cardiac Arrest Registry (VACAR). Witness status was categorised as unwitnessed, bystander witnessed, or EMS witnessed. Multivariable logistic regression was used to evaluate the association between witness status and outcomes, adjusting for age, sex, arrest location, region, aetiology, initial rhythm and year.</p><p><strong>Results: </strong>A total of 2,645 paediatric OHCAs were attended by EMS, of which 1,891 (71.5%) received a resuscitation attempt. Among EMS-treated cases, 59.8% were unwitnessed, 32.0% were bystander witnessed, and 8.1% were EMS witnessed. The incidence of unwitnessed and bystander witnessed OHCA declined over the 25-year period (p<0.001), whereas EMS witnessed incidence remained stable. After adjustment, EMS witnessed arrests were associated with significantly higher odds of survival to hospital discharge (AOR 1.91, 95% CI 1.04-3.52) and prehospital ROSC (AOR 1.83, 95% CI 1.20-2.77) compared with bystander witnessed arrests, while unwitnessed arrests had substantially lower survival across all outcomes.</p><p><strong>Conclusion: </strong>Paediatric OHCA witnessed by EMS is associated with significantly higher adjusted odds of survival compared with bystander witnessed events. These findings highlight the importance of early professional intervention and support the need for paediatric-specific strategies to improve recognition and response to these events.</p>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"111267"},"PeriodicalIF":6.0,"publicationDate":"2026-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148759996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arterial Blood Gas Parameters during Cardiopulmonary Resuscitation and Sustained Return of Spontaneous Circulation in Out-of-Hospital Cardiac Arrest: A Preplanned Secondary Analysis of the AMCPR Trial","authors":"June-Sung Kim, Youn-Jung Kim, Won Young Kim","doi":"10.1016/j.resuscitation.2026.111266","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2026.111266","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"5 1","pages":"111266"},"PeriodicalIF":6.5,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148755082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Emergency Physician Critical Care Training on Outcomes after Non-traumatic Out-of-Hospital Cardiac Arrest (OHCA).","authors":"Julian Kreutz, Susanne Betz, Franziska Hof, Birgit Markus, Klevis Mihali, Tobias Gruebl, Martin C Sassen, Bernhard Schieffer, Andreas Jerrentrup","doi":"10.1016/j.resuscitation.2026.111264","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2026.111264","url":null,"abstract":"<p><strong>Background: </strong>In physician-staffed emergency medical services (EMS) systems, emergency physicians may differ in postgraduate specialist and critical care training. Whether such differences are associated with outcomes after out-of-hospital cardiac arrest (OHCA) remains uncertain. We investigated the association between emergency physician qualification and outcomes after non-traumatic OHCA.</p><p><strong>Methods: </strong>This retrospective cohort study included adult patients with non-traumatic OHCA from the Marburg-Biedenkopf EMS region from 2018 to 2024. Patients were treated by residents, specialists without additional critical care training, or specialists with additional critical care training. The primary outcome was survival to discharge. Secondary outcomes included return of spontaneous circulation (ROSC), hospital admission with ROSC, 24-hour survival, and favourable neurological outcome. Multivariable logistic regression was performed for each endpoint with residents as reference.</p><p><strong>Results: </strong>Among 1,426 patients, any ROSC did not differ significantly between groups (39.9%, 42.5%, and 45.7%; p = 0.211). Operational response times and time to first ROSC were comparable. Specialists with additional critical care training achieved faster vascular access and earlier vasopressor administration, with fewer access failures. Survival to discharge increased across groups (12.2%, 14.4%, and 18.0%; p = 0.047). In adjusted analyses, specialists with additional critical care training had higher odds of hospital admission with ROSC (OR 1.42, 95% CI 1.05-1.93) and survival to discharge (OR 1.59, 95% CI 1.05-2.40) compared with residents.</p><p><strong>Conclusions: </strong>Additional critical care training was associated with selected prehospital procedural measures and higher odds of hospital admission with ROSC and survival to discharge. These observational findings are hypothesis-generating and do not establish causality.</p>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"111264"},"PeriodicalIF":6.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148761960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early stratification of risk for poor neurological outcome after cardiac arrest is improved with processed EEG data.","authors":"Qingchu Jin, Richard R Riker, Teresa L May, Ghanahshyam Kshirsagar, Hunter Williams, David J Gagnon, David B Seder, Raimond L Winslow","doi":"10.1016/j.resuscitation.2026.111265","DOIUrl":"10.1016/j.resuscitation.2026.111265","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the impact of adding early processed quantitative EEG biomarkers to health record data for early neurological risk stratification after cardiac arrest using machine learning.</p><p><strong>Methods: </strong>Data available during ICU admission after return of spontaneous circulation (ROSC) were collected from comatose patients, including the processed EEG metrics suppression ratio (SR) and bispectral index (BIS). Clinical data included demographics, Charlson Comorbidity Index, cardiac arrest and resuscitation details, admission vital signs, and initial laboratory results. Primary outcome was poor Cerebral Performance Category score (CPC 3-5). Six machine learning models were developed to predict hospital discharge and 6-month long-term outcome with clinical data alone, EEG (BIS-SR) data alone, and combined clinical and EEG data. Two additional operating points (high specificity for poor outcome and for good outcome) were also calculated. Feature importance was analyzed to identify the most predictive variables.</p><p><strong>Results: </strong>Among 913 patients, the median age was 59 years, most were male (69%), and 44% had an initial shockable rhythm. Poor outcome was observed in 70% at discharge and 72% at long-term assessment. The best-performing models for combined 6-h EEG and clinical data revealed AUC 0.88 (0.87-0.90) for poor long-term outcome and 0.86 (0.84-0.87) for poor discharge outcome. Combining the processed EEG and clinical data significantly improved the AUC compared to either data set alone (p < 0.001).</p><p><strong>Conclusion: </strong>The combination of early processed EEG and clinical data were best able to stratify neurological risk early after cardiac arrest using machine learning algorithms, but external validation is needed.</p>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"111265"},"PeriodicalIF":6.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Early Stratification of Risk for Poor Neurological Outcome After Cardiac Arrest Is Improved with Processed EEG Data”","authors":"Qingchu Jin, Richard R. Riker, Teresa L. May, Ghanahshyam Kshirsagar, Hunter Williams, David J. Gagnon, David B. Seder, Raimond L. Winslow","doi":"10.1016/j.resuscitation.2026.111265","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2026.111265","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"463 1","pages":"111265"},"PeriodicalIF":6.5,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148755085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arterial blood gas parameters during cardiopulmonary resuscitation and sustained return of spontaneous circulation in out-of-hospital cardiac arrest: a preplanned secondary analysis of the AMCPR trial.","authors":"June-Sung Kim, Youn-Jung Kim, Won Young Kim","doi":"10.1016/j.resuscitation.2026.111266","DOIUrl":"10.1016/j.resuscitation.2026.111266","url":null,"abstract":"<p><strong>Aim: </strong>Arterial blood gas analysis (ABGA) is not routinely performed during cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA), and is not recommended by current guidelines. This preplanned secondary analysis of the Augmented-Medication CardioPulmonary Resuscitation (AMCPR) trial evaluated whether intra-arrest PaO₂ was associated with sustained return of spontaneous circulation (ROSC).</p><p><strong>Methods: </strong>Adult OHCA patients treated at a tertiary emergency department were included. ABGA samples were obtained immediately after ultrasound-confirmed arterial catheterization and 10 and 20 min after the start of ED resuscitation; parameters included pH, PaO₂, PaCO₂, bicarbonate (HCO₃^-), and lactate. PaO₂ at the protocol-defined 10-min time point was the primary exposure and sustained ROSC the outcome; other parameters and sampling times were examined as secondary exploratory analyses.</p><p><strong>Results: </strong>Among 251 patients, 93 (37.1%) achieved sustained ROSC and 135 had a 10-min sample. In the primary analysis of these 135 patients, higher PaO₂ at 10 min was independently associated with sustained ROSC (adjusted odds ratio 1.02; 95% CI 1.01-1.02). In secondary exploratory analyses, optimal cut-offs were PaO₂ >60 mmHg and PaCO₂ <70 mmHg, whereas pH and lactate showed no consistent pattern. Twenty patients (8.0%) survived to discharge and 2 (0.8%) had a favorable neurological outcome.</p><p><strong>Conclusion: </strong>During monitored ED resuscitation for OHCA, higher intra-arrest PaO₂ was associated with sustained ROSC, although this association was only partly separable from resuscitation duration. Arterial line placement during CPR may provide physiologic information beyond hemodynamic monitoring.</p>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"111266"},"PeriodicalIF":6.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148759973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Emergency Physician Critical Care Training on Outcomes after Non-traumatic Out-of-Hospital Cardiac Arrest (OHCA)","authors":"Julian Kreutz, Susanne Betz, Franziska Hof, Birgit Markus, Klevis Mihali, Tobias Gruebl, Martin C. Sassen, Bernhard Schieffer, Andreas Jerrentrup","doi":"10.1016/j.resuscitation.2026.111264","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2026.111264","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"26 1","pages":"111264"},"PeriodicalIF":6.5,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148755081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}