ResuscitationPub Date : 2025-10-01Epub Date: 2025-07-17DOI: 10.1016/j.resuscitation.2025.110725
Lukasz Szarpak, Andrzej Krupa, Karol Momot, Michal Pruc, Michal Zembala
{"title":"Hemodynamic gains or epinephrine echoes? Interpreting interposed abdominal compression cardiopulmonary resuscitation in pediatrics.","authors":"Lukasz Szarpak, Andrzej Krupa, Karol Momot, Michal Pruc, Michal Zembala","doi":"10.1016/j.resuscitation.2025.110725","DOIUrl":"10.1016/j.resuscitation.2025.110725","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110725"},"PeriodicalIF":4.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-09-30DOI: 10.1016/j.resuscitation.2025.110850
Carly D Schmidt, Harlan McCaffery, Joseph G Kohne, Nathaniel R Hunt, Erin F Carlton
{"title":"Hospital Readmission Among Survivors of Pediatric Out-of-Hospital Cardiac Arrest: An Analysis of the Nationwide Readmissions Database.","authors":"Carly D Schmidt, Harlan McCaffery, Joseph G Kohne, Nathaniel R Hunt, Erin F Carlton","doi":"10.1016/j.resuscitation.2025.110850","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110850","url":null,"abstract":"<p><strong>Background: </strong>Out-of-hospital cardiac arrest (OHCA) is associated with significant morbidity and mortality. Among survivors, little is known about healthcare use following discharge, including hospital readmission. We sought to describe rates for and risk factors of hospital readmission in children who survive OHCA.</p><p><strong>Methods: </strong>Using the Nationwide Readmissions Database (2016-2019) we identified children who survived hospitalization following an OHCA and determined the rate and primary diagnoses of readmission within 30-days of discharge. We performed a univariate comparison and multivariable analysis to determine risk factors for readmission.</p><p><strong>Results: </strong>We identified 1,671 hospitalizations eligible for 30-day readmission analysis. Of these, 13.5% (227) had a readmission within 30 days. Index OHCAs with cardiac etiology were primarily readmitted for dysrhythmias, while those with non-cardiac etiologies were primarily admitted for respiratory failure. Longer hospitalizations and patients with comorbidities had higher odds of readmission (OR: 1.01, 95%CI: 1.001, 1.011 and OR:1.51, 95%CI: 1.04, 2.19, respectively). Admission in larger cities had lower odds of readmission (OR 0.65, 95%CI: 0.43, 0.97).</p><p><strong>Conclusion: </strong>In a nationwide cohort of children surviving to discharge following an OHCA, more than 1 in 8 children had a readmission within 30-days of discharge. Reasons for readmission differed by etiology of cardiac arrest and were more likely to occur among patients with chronic comorbidities, longer lengths of hospitalization and those admitted to small cities or rural areas. Thus, tailored anticipatory guidance and multidisciplinary follow-up practices may be important to prevent readmission.</p>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110850"},"PeriodicalIF":4.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-09-29DOI: 10.1016/j.resuscitation.2025.110847
Rohit S Loomba
{"title":"Cerebral autoregulation: why predict a monitored value when it's already being monitored?","authors":"Rohit S Loomba","doi":"10.1016/j.resuscitation.2025.110847","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110847","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110847"},"PeriodicalIF":4.6,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-09-29DOI: 10.1016/j.resuscitation.2025.110852
Chika Nishiyama, Takeyuki Kiguchi, Masashi Okubo, Rabab Al-Araji, Edilberto Amorim, Hajriz Alihodžić, Enrico Baldi, Frankie Beganton, Claudio Benvenuti, Scott Booth, Janet E Bray, Sheldon Cheskes, Erika Frischknecht Christensen, Ruggero Cresta, Bridget Dicker, Therese Djarv, Jan-Thorsten Gräsner, Stuart Howell, Xavier Jouven, Hao-Yang Lin, Matthew Huei-Ming Ma, Eloi Marijon, Siobhán Masterson, Bryan McNally, Jerry P Nolan, Marcus Eh Ong, Jeong Ho Park, Gavin D Perkins, Martin Quinn, Lisa Rück, Simone Savastano, Nur Shahidah, Sang Do Shin, Jasmeet Soar, Ingvild B M Tjelmeland, Courtney Truong, Christian Vaillancourt, Jan Wnent, Joyce Yeung, Taku Iwami
{"title":"Characteristics of Out-of-hospital Cardiac Arrest from 2018 to 2021 across the World: Third Report from the International Liaison Committee on Resuscitation (ILCOR) Research and Registries Committee.","authors":"Chika Nishiyama, Takeyuki Kiguchi, Masashi Okubo, Rabab Al-Araji, Edilberto Amorim, Hajriz Alihodžić, Enrico Baldi, Frankie Beganton, Claudio Benvenuti, Scott Booth, Janet E Bray, Sheldon Cheskes, Erika Frischknecht Christensen, Ruggero Cresta, Bridget Dicker, Therese Djarv, Jan-Thorsten Gräsner, Stuart Howell, Xavier Jouven, Hao-Yang Lin, Matthew Huei-Ming Ma, Eloi Marijon, Siobhán Masterson, Bryan McNally, Jerry P Nolan, Marcus Eh Ong, Jeong Ho Park, Gavin D Perkins, Martin Quinn, Lisa Rück, Simone Savastano, Nur Shahidah, Sang Do Shin, Jasmeet Soar, Ingvild B M Tjelmeland, Courtney Truong, Christian Vaillancourt, Jan Wnent, Joyce Yeung, Taku Iwami","doi":"10.1016/j.resuscitation.2025.110852","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110852","url":null,"abstract":"<p><strong>Background: </strong>The International Liaison Committee on Resuscitation (ILCOR) Research and Registries Committee previously reported 2015 data on systems of care and outcomes for out-of-hospital cardiac arrest (OHCA) from 16 registries and 2015 to 2017 data from 15 registries. To describe updated data on OHCA, we report the characteristics of OHCAs from 2018 through 2021.</p><p><strong>Methods: </strong>We invited national and regional population-based OHCA registries to participate voluntarily and included emergency medical services-treated OHCAs. We collected descriptive summary data of core elements of the Utstein OHCA registry template from 2018 through 2021 at each registry.</p><p><strong>Results: </strong>Thirteen national and five regional registries from North America, Europe, Asia, and Oceania were included in this report. The provision of bystander cardiopulmonary resuscitation ranged from 9.6% to 83.8% (median 61.7%) and shocks by public access automated external defibrillator from 0.5% to 11.7% (median 2.3%) in 2021. Survival to hospital discharge or 30-day survival for bystander-witnessed shockable OHCA ranged from 19.9% to 44.4% (median 28.3%), and neurologically favourable outcome ranged from 9.5% to 35.1% (median 22.0%) in 2021. The majority of registries showed that survival and favourable neurological outcomes were lower in the 2020-2021 COVID-19 pandemic period compared with those in 2018-2019.</p><p><strong>Conclusion: </strong>This report from ILCOR presents summary data for OHCA systems of care and outcomes from 2018 through 2021 from 18 national and regional OHCA registries worldwide. We observed a persisting wide variability in OHCA characteristics and outcomes across registries and the potential impact of the COVID-19 pandemic within registries.</p>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110852"},"PeriodicalIF":4.6,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-09-29DOI: 10.1016/j.resuscitation.2025.110848
{"title":"The beating heart of newborn resuscitation (A pulse check on heart rate determination at birth).","authors":"","doi":"10.1016/j.resuscitation.2025.110848","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110848","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110848"},"PeriodicalIF":4.6,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-09-26DOI: 10.1016/j.resuscitation.2025.110839
Marcel Cg van de Poll, Anina F van de Koolwijk
{"title":"Cost-effectiveness in extracorporeal CPR: moving from optimism to realism.","authors":"Marcel Cg van de Poll, Anina F van de Koolwijk","doi":"10.1016/j.resuscitation.2025.110839","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110839","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110839"},"PeriodicalIF":4.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-09-26DOI: 10.1016/j.resuscitation.2025.110845
Wendy Hardyman, Gareth Clegg
{"title":"Enhancing public preparedness to act during cardiac arrest: Embedding CPR and defibrillation awareness in the UK Driving Theory Test.","authors":"Wendy Hardyman, Gareth Clegg","doi":"10.1016/j.resuscitation.2025.110845","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110845","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110845"},"PeriodicalIF":4.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-09-24DOI: 10.1016/j.resuscitation.2025.110838
Giulia M Benedetti, Andrea C Pardo, LNelson Sanchez-Pinto, Megan Straley, Mark S Wainwright, Jonathan E Kurz, Craig A Press
{"title":"Predicting Pediatric Cardiac Arrest Outcomes Using Early Quantitative EEG.","authors":"Giulia M Benedetti, Andrea C Pardo, LNelson Sanchez-Pinto, Megan Straley, Mark S Wainwright, Jonathan E Kurz, Craig A Press","doi":"10.1016/j.resuscitation.2025.110838","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110838","url":null,"abstract":"<p><strong>Aim: </strong>Accuracy of neuroprognostication after pediatric cardiac arrest (CA) is critical for directing clinical care. Current limitations include imprecise neuroprognostication models, inability to discriminate between degrees of disability, and lack of modifiable post-CA biomarkers. Models including quantitative EEG (qEEG) characteristics may improve post-CA prognostic accuracy.</p><p><strong>Methods: </strong>Retrospective multicenter cohort of children (3mo-18yr) without return to neurologic baseline post-CA at two pediatric tertiary care hospitals (2010-2016) with ≥6-hours of EEG within 24-hours post-CA and baseline Pediatric Cerebral Performance Category (PCPC) 1-3. Primary outcome measure was 6-month PCPC dichotomized into favorable (1-3) and unfavorable (4-6 and Δ>1). Training and validation sets were derived from clinical variables, qualitative EEG (qualEEG) features, and qEEG analysis using Persyst software.</p><p><strong>Results: </strong>Among 221 subjects, 84 (38%) had favorable 6-month outcomes. All models including clinical features (AUC 0.73 [0.59-0.87]), qualEEG (0.90 [0.81-0.97]) and qEEG features (0.85 [0.74-0.94]) predict outcomes well. A parsimonious model incorporating clinical, qualEEG and qEEG variables had an AUC of 0.92 (0.85-0.97) for predicting outcome. Increased SR was associated with degree of disability and unfavorable outcomes. Machine learning models were not superior to the more transparent parsimonious model.</p><p><strong>Conclusions: </strong>qEEG features measured with 24-hours post-CA add to predictive outcome models and can be trended at the bedside. SR is an objective measure that may improve the precision of outcome prediction. qEEG features may be targetable dynamic brain injury biomarkers which could aid in future studies of neuroprotective interventions.</p>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110838"},"PeriodicalIF":4.6,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145177909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}