{"title":"Factors associated with automated external defibrillator use in out-of-hospital cardiac arrest by type of lay rescuers: a Japanese nationwide, population-based descriptive study","authors":"Yuto Makino, Takeyuki Kiguchi, Norihiro Nishioka, Yohei Okada, Tomonari Shimamoto, Tasuku Matsuyama, Chika Nishiyama, Kousuke Kiyohara, Tetsuhisa Kitamura, Taku Iwami","doi":"10.1016/j.resuscitation.2025.110691","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110691","url":null,"abstract":"Prompt automated external defibrillator (AED) use and shock delivery are crucial for improving outcomes in patients with out-of-hospital cardiac arrest (OHCA). This study was aimed at elucidating the current patterns of AED use by lay rescuers in Japan and exploring the associated factors by lay rescuer type.","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"30 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-20DOI: 10.1016/j.resuscitation.2025.110692
Ho Kyung Sung, Yang Hyun Cho, In Seok Jung, Hyung Soo Kim, Su Jin Kim, Jun Ho Lee, Hee-Jung Kim, Ji-Eon Kim, Jae-Seung Jung
{"title":"Trends and Institutional Patterns of Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest in Korea: A Nationwide Analysis, 2016–2023","authors":"Ho Kyung Sung, Yang Hyun Cho, In Seok Jung, Hyung Soo Kim, Su Jin Kim, Jun Ho Lee, Hee-Jung Kim, Ji-Eon Kim, Jae-Seung Jung","doi":"10.1016/j.resuscitation.2025.110692","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110692","url":null,"abstract":"While the clinical effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) has gained increasing attention, its real-world utilization, patient selection, and system-level implementation remain incompletely understood.","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"122 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-19DOI: 10.1016/j.resuscitation.2025.110688
Bálint Bánfai, Boróka Jobb, József Betlehem, Henrietta Bánfai-Csonka
{"title":"Improving feasibility of video-assisted cardiopulmonary resuscitation when only one lay responder is present","authors":"Bálint Bánfai, Boróka Jobb, József Betlehem, Henrietta Bánfai-Csonka","doi":"10.1016/j.resuscitation.2025.110688","DOIUrl":"10.1016/j.resuscitation.2025.110688","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"214 ","pages":"Article 110688"},"PeriodicalIF":6.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-19DOI: 10.1016/j.resuscitation.2025.110687
Marco Mion, Vicky L. Joshi, Paul Swindell, Thomas R. Keeble, 10 Years Together Conference HCP-track Faculty
{"title":"They survived – Now what? The case for integrated recovery pathways for cardiac arrest survivors","authors":"Marco Mion, Vicky L. Joshi, Paul Swindell, Thomas R. Keeble, 10 Years Together Conference HCP-track Faculty","doi":"10.1016/j.resuscitation.2025.110687","DOIUrl":"10.1016/j.resuscitation.2025.110687","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"214 ","pages":"Article 110687"},"PeriodicalIF":6.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-16DOI: 10.1016/j.resuscitation.2025.110676
Daniel Stromberg, Tia T Raymond, Gabriela Centers, Zahra Vaez, Sangmo Je, Anne Thomas, Vinay Nadkarni, Daniel P Howsmon
{"title":"Interposed abdominal compression CPR in pediatric cardiac arrest: early results from a multicenter comparison to standard CPR.","authors":"Daniel Stromberg, Tia T Raymond, Gabriela Centers, Zahra Vaez, Sangmo Je, Anne Thomas, Vinay Nadkarni, Daniel P Howsmon","doi":"10.1016/j.resuscitation.2025.110676","DOIUrl":"10.1016/j.resuscitation.2025.110676","url":null,"abstract":"<p><strong>Introduction: </strong>Interposed abdominal compression CPR (IAC-CPR) is an American Heart Association Class IIb recommended adjunct to standard CPR (S-CPR) that employs abdominal counter-pulsation during the \"diastolic\" (release) phase of thoracic compressions. Animal and adult studies have demonstrated IAC-CPR augmentation of venous return to the right heart with enhanced cardiac output, and increased diastolic blood pressure (DBP) with improved retrograde flow to the coronary arteries and brain. We hypothesized that IAC-CPR (compared with S-CPR) would result in higher DBP which has been associated with improved survival outcomes in pediatric cardiac intensive care unit (PCICU) patients.</p><p><strong>Methods: </strong>As participants in a prospective, multicenter, quality assurance collaborative (PediRes-Q.org) from Dec 2020 - July 2024, three participating PCICU sites used IAC-CPR within usual care, and systematically collected hemodynamic data from 1 to 2 min sequential epochs of S-CPR and IAC-CPR within the same patient. IAC-CPR training via video (https://youtu.be/cd3Gxu7Maqk), digital slide presentation, and in-person mannequin demonstration of technique competency at each participating center were required. Single rescuer resuscitation of children ≤ 3 years old proceeded with S-CPR for 1-2 min, followed by 1-2 min of IAC-CPR. Choice of CPR technique for the remainder of the cardiac arrest event was then left to the clinical care team. Hemodynamic waveforms from epochs of S-CPR and IAC-CPR were compared. Return of spontaneous circulation (ROSC), return of circulation (ROC) with ECMO, and survival to hospital discharge or to 30 days were recorded. Neurological outcome was assessed pre-arrest and at hospital discharge by the Pediatric Cerebral Performance Category (PCPC) score. Favorable neurologic outcome was considered PCPC category 1-2, or no change from pre-arrest baseline.</p><p><strong>Results: </strong>Seventeen infants with complex congenital heart disease were included, the majority of which (14/17) were single ventricle patients who experienced arrest postoperatively. Intervention analyses demonstrated a DBP increase of 11.6 mmHg during IAC-CPR versus S-CPR (95% CI [2.2-21.1], p = 0.018, adjusted for non-stationarity and correlations in individual time series). Peak systolic blood pressure (SBP) increased by 15.4 mmHg during IAC-CPR versus S-CPR (95% CI [0.51 - 30.2], p = 0.044, adjusted for non-stationarity and correlations in individual time series). ROSC was achieved in 11/17 (65%), and ROC with ECMO in 5/17 (29%). Survival to hospital discharge or to 30 days occurred in 8/17 (47%), and all had a favorable neurologic outcome. No complications attributable to IAC-CPR were found.</p><p><strong>Conclusions: </strong>IAC-CPR was associated with significant improvements in both DBP and SBP compared to S-CPR technique in pediatric ICU patients with complex congenital heart disease. This underscores the need for study of IA","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":" ","pages":"110676"},"PeriodicalIF":6.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-16DOI: 10.1016/j.resuscitation.2025.110686
Alice Lagebrant , Claudio Sandroni , Jerry P. Nolan , Jan Bělohlávek , Alain Cariou , Riccardo Carrai , Josef Dankiewicz , Anders Morten Grejs , Antonello Grippo , Christian Hassager , Janneke Horn , Matthias Haenggi , Janus C. Jakobsen , Thomas R. Keeble , Hans Kirkegaard , Jesper Kjaergaard , Michael A. Kuiper , Byung Kook Lee , Dong Hun Lee , Helena Levin , Marion Moseby-Knappe
{"title":"Prediction of good functional outcome decreases diagnostic uncertainty in unconscious survivors after out-of-hospital cardiac arrest","authors":"Alice Lagebrant , Claudio Sandroni , Jerry P. Nolan , Jan Bělohlávek , Alain Cariou , Riccardo Carrai , Josef Dankiewicz , Anders Morten Grejs , Antonello Grippo , Christian Hassager , Janneke Horn , Matthias Haenggi , Janus C. Jakobsen , Thomas R. Keeble , Hans Kirkegaard , Jesper Kjaergaard , Michael A. Kuiper , Byung Kook Lee , Dong Hun Lee , Helena Levin , Marion Moseby-Knappe","doi":"10.1016/j.resuscitation.2025.110686","DOIUrl":"10.1016/j.resuscitation.2025.110686","url":null,"abstract":"<div><h3>Purpose</h3><div>To explore modifications of the 2021 European Resuscitation Council/European Society of Intensive Care Medicine (ERC/ESICM) guideline algorithm for neuroprognostication after cardiac arrest to improve its prognostic accuracy.</div></div><div><h3>Methods</h3><div>Post-hoc analysis of four prospective multicentre studies (TTM, TTM2, KORHN and ProNeCA). We raised the Glasgow Coma Scale motor (GCS-M) inclusion threshold at 72 h after cardiac arrest from the current GCS-M < 4 to GCS-M < 6 (all unconscious patients). Secondly, we included good outcome predictors (GCS-M 4–5, neuron-specific enolase < 17 µg/L, benign electroencephalography patterns ≤ 72 h post-arrest and normal magnetic resonance imaging at 72–168 h post-arrest) in the algorithm. Functional outcome was assessed dichotomously at six months, including modified Rankin Scale 0–3, Cerebral Performance Category 1–2 or Glasgow Outcome Scale 4–5 (no symptoms to moderate disability) as good outcome.</div></div><div><h3>Results</h3><div>We analysed 3,388 patients, of whom 2,079 had GCS-M < 4 at ≥ 72 h. Of the 874 patients identified by the 2021 ERC/ESICM poor outcome criteria, 870 had poor functional outcome (specificity: 99.6% [95%CI 99.0–99.9]). Using the GCS-M < 6 threshold, 366 more patients entered the algorithm (<em>N</em> = 2,445). Seven more patients with poor outcomes were identified, with close to identical specificity. Good outcome predictors thereafter identified 673 patients with potential recovery, of whom 411 (61%) had a good functional outcome at six months. With the updated algorithm, the number of prognosticated patients with an indeterminate prognosis decreased from 1,205/2,079 (58%) to 891/2,445 (36%).</div></div><div><h3>Conclusion</h3><div>Raising the GCS-M inclusion threshold and adding favourable predictors to the 2021 ERC/ESICM prognostication algorithm reduced prognostic uncertainty without increasing falsely pessimistic predictions.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"214 ","pages":"Article 110686"},"PeriodicalIF":6.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-14DOI: 10.1016/j.resuscitation.2025.110679
Simon-Pierre Corcostegui, Clotilde Dupré la Tour, Stéphane Travers, Daniel Jost, Clément Derkenne
{"title":"Intubation during cardiac arrest: defibrillator trace analysis should be the ultimate judge","authors":"Simon-Pierre Corcostegui, Clotilde Dupré la Tour, Stéphane Travers, Daniel Jost, Clément Derkenne","doi":"10.1016/j.resuscitation.2025.110679","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110679","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"4 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-14DOI: 10.1016/j.resuscitation.2025.110685
Marco Mion, Vicky L. Joshi
{"title":"Time for consensus: establishing core outcomes meaningful to survivors of out-of-hospital cardiac arrest","authors":"Marco Mion, Vicky L. Joshi","doi":"10.1016/j.resuscitation.2025.110685","DOIUrl":"10.1016/j.resuscitation.2025.110685","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"214 ","pages":"Article 110685"},"PeriodicalIF":6.5,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-14DOI: 10.1016/j.resuscitation.2025.110682
Lukasz Szarpak, Michal Pruc, Andrzej Krupa
{"title":"Prognostic Nihilism or Pragmatic Withdrawal? Reevaluating early withdrawal of life-sustaining therapy in neurological causes of cardiac arrest","authors":"Lukasz Szarpak, Michal Pruc, Andrzej Krupa","doi":"10.1016/j.resuscitation.2025.110682","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110682","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"103 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2025-06-14DOI: 10.1016/j.resuscitation.2025.110683
Michel Galinski, Bruno Simonnet, Cédric Gil-jardiné
{"title":"Reply to: “Intubation during cardiac arrest: defibrillator trace analysis should be the ultimate judge”","authors":"Michel Galinski, Bruno Simonnet, Cédric Gil-jardiné","doi":"10.1016/j.resuscitation.2025.110683","DOIUrl":"https://doi.org/10.1016/j.resuscitation.2025.110683","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"28 1","pages":""},"PeriodicalIF":6.5,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}