ResuscitationPub Date : 2026-05-01Epub Date: 2026-02-16DOI: 10.1016/j.resuscitation.2026.111018
Theerapon Jariyasakoolroj , Karen O’Connell , Thomas MacDonald , John Breslin , Jennifer Murphy , Crystal MacDonald , Tara Neubrand , Laura Rochford , Sage Myers , Benjamin Kerrey , Aaron Donoghue
{"title":"The impact of tracheal intubation attempts on chest compression fraction during pediatric CPR: a report from the Videography in Pediatric Resuscitation (VIPER) collaborative","authors":"Theerapon Jariyasakoolroj , Karen O’Connell , Thomas MacDonald , John Breslin , Jennifer Murphy , Crystal MacDonald , Tara Neubrand , Laura Rochford , Sage Myers , Benjamin Kerrey , Aaron Donoghue","doi":"10.1016/j.resuscitation.2026.111018","DOIUrl":"10.1016/j.resuscitation.2026.111018","url":null,"abstract":"<div><h3>Aim</h3><div>To examine the association between tracheal intubation (TI) attempts and chest compression (CC) pauses on chest compression fraction (CCF) during pediatric CPR across a network of emergency departments.</div></div><div><h3>Methods</h3><div>Prospective observational cohort by the Videography in Pediatric Resuscitation (VIPER) Collaborative. Videorecorded CPR events were reviewed to measure CC pauses and characterize TI attempts. CCF was calculated as the proportion of time compressions were delivered during each event. Events were categorized based on whether TI-associated pauses occurred, and CCF was compared using Wilcoxon rank-sum testing.</div></div><div><h3>Results</h3><div>A total of 183 CPR events were included. The median event duration was 971 s (IQR 645–1432 s), and the median CCF was 92% (IQR 90–95%). TI was attempted in 73 events (40%), most commonly once per event, with a median laryngoscopy duration of 34 s (IQR 24–53 s). CC pauses occurred during TI attempts in 29 events, with a median pause duration of 20 s (IQR 10–33 s). TI success rates did not differ significantly between attempts with and without associated CC pauses. There was no significant difference in CCF between events with TI-associated CC pauses (median 92%, IQR 89–94%) and those without such pauses (median 93%, IQR 89–94%; <em>p</em> = 0.11).</div></div><div><h3>Conclusions</h3><div>TI-associated CC pauses were often longer than recommended but did not reduce overall CCF. There were no significant differences in median pause duration or the frequency of prolonged pauses between events with and without pauses associated with TI. Further studies should explore respiratory parameters during pediatric CPR to clarify the optimal method for assisted ventilation.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"222 ","pages":"Article 111018"},"PeriodicalIF":4.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146209346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to: “UDCD ORGANS ARE STILL VALID”, letter from Alonso Mateos et al.","authors":"Claudio Sandroni , Sofia Cacciola , Sonia D’Arrigo , Tommaso Scquizzato , Jasmeet Soar","doi":"10.1016/j.resuscitation.2025.110768","DOIUrl":"10.1016/j.resuscitation.2025.110768","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"222 ","pages":"Article 110768"},"PeriodicalIF":4.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2026-05-01Epub Date: 2025-12-13DOI: 10.1016/j.resuscitation.2025.110924
Lingyi Meng, Mengda Yu
{"title":"When ground truth is not static: rethinking AI performance in occlusive MI detection from post-MI ECGs","authors":"Lingyi Meng, Mengda Yu","doi":"10.1016/j.resuscitation.2025.110924","DOIUrl":"10.1016/j.resuscitation.2025.110924","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"222 ","pages":"Article 110924"},"PeriodicalIF":4.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145759473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2026-05-01Epub Date: 2025-09-06DOI: 10.1016/j.resuscitation.2025.110810
Alberto Hernández-Tejedor, Vanesa Gónzález Puebla, Ervigio Corral Torres, Sara Isabel Montero Hernández
{"title":"Reply to Letter: Question on the occurrence of lung injury in patients receiving chest compression synchronized ventilation in the SYMEVECA study","authors":"Alberto Hernández-Tejedor, Vanesa Gónzález Puebla, Ervigio Corral Torres, Sara Isabel Montero Hernández","doi":"10.1016/j.resuscitation.2025.110810","DOIUrl":"10.1016/j.resuscitation.2025.110810","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"222 ","pages":"Article 110810"},"PeriodicalIF":4.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2026-05-01Epub Date: 2026-03-05DOI: 10.1016/j.resuscitation.2026.111038
Hasan Khaled Abdel Rahman , Nikolaj Blomberg , Malea Benediktsson , Emma Engelhardt , Helle Collatz Christensen , Anne Craveiro Brøchner , Søren Mikkelsen
{"title":"Community first-responders in cardiac arrest. Effect on survival? A comprehensive Danish study of 29,445 out-of-hospital cardiac arrests","authors":"Hasan Khaled Abdel Rahman , Nikolaj Blomberg , Malea Benediktsson , Emma Engelhardt , Helle Collatz Christensen , Anne Craveiro Brøchner , Søren Mikkelsen","doi":"10.1016/j.resuscitation.2026.111038","DOIUrl":"10.1016/j.resuscitation.2026.111038","url":null,"abstract":"<div><h3>Aim</h3><div>Since 2018, Denmark has implemented a national community first-responder system, activated by the emergency dispatch centre, to supplement local first-responder programs. The responders are dispatched to all out-of-hospital cardiac arrests (OHCA). This study aimed to investigate the effect of community first-responders on survival following OHCA.</div></div><div><h3>Methods</h3><div>A manual review of prehospital medical records for all 29,445 OHCA cases in Denmark from 2018 through 2023. The type of responder who initiated resuscitative efforts was stratified into three main groups: bystanders present at the incident, community first-responders, or ambulance personnel. The primary outcome was survival at 30 days and 365 days.</div></div><div><h3>Results</h3><div>After exclusions, 21,413 patients were analysed, of which initial resuscitation efforts were provided by on-scene bystanders (12,613), community first-responders (2155), or emergency medical service (EMS) personnel (6140). In 505 cases, the provider of the initial CPR was unclear. Provision of initial resuscitative efforts by on-scene bystanders before ambulance arrival was associated with odds ratios of 2.42 for 30-day survival and 2.51 for 365-day survival, compared with patients whose first resuscitation was not initiated before EMS arrival.</div><div>There was no significant difference in outcome when first resuscitation efforts were provided by community first responders or delayed until EMS arrival.</div></div><div><h3>Conclusion</h3><div>In OHCA, basic life support initiated by bystanders was associated with a survival rate more than twice that of OHCA patients whose first resuscitation was provided by community first-responders or ambulance personnel. Our findings support early resuscitation, but we found no evidence to support dispatching community first-responders to OHCA.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"222 ","pages":"Article 111038"},"PeriodicalIF":4.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147373065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2026-05-01Epub Date: 2025-06-14DOI: 10.1016/j.resuscitation.2025.110682
Lukasz Szarpak, Michal Pruc, Andrzej Krupa
{"title":"Prognostic nihilism or pragmatic withdrawal? Reevaluating early withdrawal of life-sustaining therapy in neurological causes of cardiac arrest","authors":"Lukasz Szarpak, Michal Pruc, Andrzej Krupa","doi":"10.1016/j.resuscitation.2025.110682","DOIUrl":"10.1016/j.resuscitation.2025.110682","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"222 ","pages":"Article 110682"},"PeriodicalIF":4.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2026-05-01Epub Date: 2024-12-05DOI: 10.1016/j.resuscitation.2024.110453
Andreas Friedrich Christoph Breuer-Kaiser , Rolf Lefering , Thomas Peter Weber , Jan-Thorsten Gräsner , Jan Wnent
{"title":"Use of CPR feedback devices to treat out-of-hospital cardiac arrest in Germany: Associated with improved ROSC-rates, but infrequent usage, in a registry-based analysis of 107,548 cases","authors":"Andreas Friedrich Christoph Breuer-Kaiser , Rolf Lefering , Thomas Peter Weber , Jan-Thorsten Gräsner , Jan Wnent","doi":"10.1016/j.resuscitation.2024.110453","DOIUrl":"10.1016/j.resuscitation.2024.110453","url":null,"abstract":"<div><h3>Introduction</h3><div>Out-of-hospital cardiac arrest is a leading cause of mortality in Europe. Quality cardiopulmonary resuscitation, particularly of chest compressions, is crucial. Real-time audiovisual feedback (RTAVF) devices aim to enhance chest compression quality. Recent studies on these tools have reported improved outcomes for in-hospital but not for out-of-hospital cardiac arrest. This registry-based, retrospective study investigated the use of feedback-devices by emergency medical services personnel to treat out-of-hospital cardiac arrest in Germany and assessed its effect on return of spontaneous circulation (ROSC).</div></div><div><h3>Methods</h3><div>We analyzed 107,548 records from the German Resuscitation Registry between 2015 and 2022 and compared patient outcomes of patients treated with feedback devices or not. ROSC rates both at any time and at hospital admission were compared to expected rates based on the “Rosc After Cardiac Arrest” (RACA) score. Furthermore, a generalized linear mixed methods model was calculated to receive an adjusted effect for those devices.</div></div><div><h3>Results</h3><div>Feedback-devices were used in 17.5% of cases overall, rising from 7.1% (2015) to 23.2% (2022). Patients resuscitated with feedback devices had a 2.6% higher rate of hospital admission with spontaneous circulation (35.9% vs. 33.3%). In both groups, the ROSC rates were higher than predicted by the RACA score. After multivariable adjustment we found a minor effect for RTAVF use on any ROSC (odds ratio 1.09, 95% confidence interval 1.04–1.14), but no effect on the ROSC rate on admission (odds ratio 0.98, 95% confidence interval 0.93–1.03).</div></div><div><h3>Conclusion</h3><div>We could show a minor association between the use of feedback devices and any ROSC, but not for ROSC on hospital admission, in out-of-hospital cardiac arrest patients in a generalized linear mixed model. Further research should address implementation strategies, sustainability and evaluate its effectiveness for other applications.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"222 ","pages":"Article 110453"},"PeriodicalIF":4.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ResuscitationPub Date : 2026-05-01Epub Date: 2026-02-20DOI: 10.1016/j.resuscitation.2026.111027
Stefano Zorzi , Aaron Blandino Ortiz , Marco Pasetto , Marco Anderloni , Gaia Furlan , Marina López-Olivencia , Martina Polato , Andrea Vieno , Mario Zaccarelli , Mauro Oddo , Katia Donadello , Rosanna Vaschetto , Elisa Goveau Bogossian , Fabio Silvio Taccone
{"title":"Quantitative pupillometry index to prognosticate neurological outcome in unconscious cardiac arrest patients","authors":"Stefano Zorzi , Aaron Blandino Ortiz , Marco Pasetto , Marco Anderloni , Gaia Furlan , Marina López-Olivencia , Martina Polato , Andrea Vieno , Mario Zaccarelli , Mauro Oddo , Katia Donadello , Rosanna Vaschetto , Elisa Goveau Bogossian , Fabio Silvio Taccone","doi":"10.1016/j.resuscitation.2026.111027","DOIUrl":"10.1016/j.resuscitation.2026.111027","url":null,"abstract":"<div><h3>Background</h3><div>The evaluation of pupillary reactivity is crucial in assessing unconscious patients following cardiac arrest (CA). An abnormal Neurological Pupil Index (NPi) is highly specific to predict unfavourable neurological outcome (UO). A new index, the Quantitative Pupillometry Index (QPI) has emerged; however, there are no prognostic data in CA patients. This study compared the prognostic value of NPi and QPI in patients after CA.</div></div><div><h3>Methods</h3><div>This is a prospective observational study conducted at two University hospitals in Belgium and Spain. We collected data from unconsciousness (i.e. Glasgow Coma Scale <9) patients admitted to the Intensive Care Unit after successful resuscitation from CA between March 2022 and October 2024. Measurements of NPi and QPI were performed twice at 24, 48 and 72 h after CA. Follow-up was conducted by telephone interview or follow-up visits; UO was considered as Glasgow-Pittsburgh Cerebral Performance Category 3–5 at 3 months.</div></div><div><h3>Results</h3><div>193 patients were screened and 111 included in the final analysis. ICU mortality occurred in 69 (62.2%) patients, while 79 (71%) patients had an UO. Patients with UO showed a lower NPi and QPI during the first three days. The QPI showed an increasing positive predictive value over time; at 72 h, a QPI ≤ 2 showed a sensitivity of 60.4 [46.0–73.5]% and a specificity of 100 [87.2–100]% to predict UO, while a NPi ≤ 2 showed a sensitivity of 24.5 [13.8–38.3]% and a specificity of 100 [86.8–100]%.</div></div><div><h3>Conclusions</h3><div>Abnormal QPI had comparable specificity and a higher sensitivity than NPi in predicting UO at 3 months in comatose patients after CA.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"222 ","pages":"Article 111027"},"PeriodicalIF":4.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146777341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}