European registry of cardiac arrest study THREE (EuReCa- THREE) - EMS response time influence on outcome in Europe.

IF 6.5 1区医学 Q1 CRITICAL CARE MEDICINE

Resuscitation Pub Date : 2025-07-07 DOI:10.1016/j.resuscitation.2025.110704

Jan-Thorsten Gräsner, Jan Wnent, Rolf Lefering, Johan Herlitz, Siobhan Masterson, Holger Maurer, Gavin D Perkins, Fernando Rosell Ortiz, Ingvild B M Tjelmeland, Drilon Kamishi, Maximilian Moertl, Pierre Mols, Hajriz Alihodzic, Marios Ioannides, Anatolij Truhlář, Valentine Baert, Nikolaos Nikolaou, Noemi Molnar, Bergthor Steinn Jonsson, Federico Semeraro, Asta Krikscionaitiene, Carlo Clarens, Christopher Giordimaina, Remy Stieglis, Anna Zadlo, Vitor Hugo Correia, Diana Cimpoesu, Violetta Raffay, Stefan Trenkler, Matej Strnad, Jose Ignacio Ruiz, Anneli Strømsøe, André Wilmes, Scott Booth, Leo Bossaert

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引用次数: 0

Abstract

Background: Throughout Europe there are important differences in the structure and characteristics of Emergency Medical Services (EMS) and their response to out-of-hospital cardiac arrest (OHCA). The primary aim of EuReCa-THREE was to examine the epidemiology of cardiac arrest in Europe and explore the association between EMS response time and survival.

Methods: EuReCa-THREE was an international, prospective, registry-based, cohort study, for which data were collected from 1 September to 30 November 2022 from 28 countries. Primary research questions were focused on assessing time intervals and their impact on outcomes.

Results: Of the 45,251 confirmed OHCA cases, 32,033 were treated by the EMS i.e. resuscitation started or continued. The mean response time was 12.2 min (range 6.4-22.8), with 25% of patients were reached within 7 min. For all cases where resuscitation was started or continued by EMS, the rate of any ROSC was 31.2% (range 17.0-42.7), ROSC sustained until arrival at the emergency department and transfer of care (survived event) was 22.5%(range 12.3-25.5) and overall survival was 7.5% (range 3.1-35.0), (incidence 4.0 per 100,000 inhabitants, range 1.7-24.6).

Conclusion: The results of EuReCa-THREE highlight continuing variation in the incidence, management and outcomes from OHCA across Europe. For patients who were EMS-treated, results indicate clear associations between response times and the likelihood of survival.

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欧洲心脏骤停登记研究三(EuReCa- Three) - EMS反应时间对欧洲结果的影响。

背景：在整个欧洲，紧急医疗服务（EMS）的结构和特征及其对院外心脏骤停（OHCA）的反应存在重要差异。EuReCa-THREE的主要目的是检查欧洲心脏骤停的流行病学，并探讨EMS反应时间与生存之间的关系。EuReCa-THREE是一项国际性、前瞻性、基于注册的队列研究，数据收集于2022年9月1日至11月30日，来自28个国家。主要研究问题集中在评估时间间隔及其对结果的影响。结果：在45,251例OHCA确诊病例中，32,033例接受了EMS治疗，即开始或继续复苏。平均反应时间为12.2分钟（范围6.4-22.8），其中25%的患者在7分钟内到达。在EMS开始或继续复苏的所有病例中，任何ROSC的发生率为31.2%（范围17.0-42.7），ROSC持续到到达急诊科和转移护理（存活事件）为22.5%（范围12.3-25.5），总生存率为7.5%（范围3.1-35.0），（发病率4.0 / 100,000居民，范围1.7-24.6）。结论：EuReCa-THREE的结果突出了欧洲OHCA的发病率、管理和结局的持续变化。对于接受ems治疗的患者，结果表明反应时间与生存可能性之间存在明确的关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Resuscitation 医学-急救医学

CiteScore

12.00

自引率

18.50%

发文量

556

审稿时长

21 days

期刊介绍： Resuscitation is a monthly international and interdisciplinary medical journal. The papers published deal with the aetiology, pathophysiology and prevention of cardiac arrest, resuscitation training, clinical resuscitation, and experimental resuscitation research, although papers relating to animal studies will be published only if they are of exceptional interest and related directly to clinical cardiopulmonary resuscitation. Papers relating to trauma are published occasionally but the majority of these concern traumatic cardiac arrest.