Resuscitation最新文献

{"title":"Towards a common terminology of ventilation during cardiopulmonary resuscitation","authors":"Nicolas Segond ,&nbsp;Johannes Wittig ,&nbsp;Wolfgang J. Kern ,&nbsp;Simon Orlob","doi":"10.1016/j.resuscitation.2025.110511","DOIUrl":"10.1016/j.resuscitation.2025.110511","url":null,"abstract":"<div><div>Manual and mechanical ventilation during cardiopulmonary resuscitation are critical yet poorly understood components of resuscitation care. In recent years, intra-arrest ventilation has been the subject of a growing number of laboratory and clinical investigations. Essential components to accurately interpret or reproduce original investigations are the exact measurement and transparent reporting of key ventilation parameters, such as volumes and airway pressures obtained during ongoing cardiopulmonary resuscitation. Chest compressions lead to frequent intrathoracic and intrapulmonary pressure rises which interact with artificial ventilation. The resulting unique phenomena during continuous chest compressions with asynchronous ventilation and an advanced airway necessitate a nuanced conceptualization supported by a common terminology.</div><div>Based on previous original investigations and observations, we describe intra-arrest ventilation parameters and propose a common terminology integrating established and novel concepts. The proposed terminology may serve as a methodological and reporting consideration for future research of intra-arrest ventilation. Additionally, it may serve as a foundation for an authoritative scientific consensus process, which may further facilitate the transparent reporting and reproducible science needed to understand cardiopulmonary resuscitation and improve survival for cardiac arrest patients.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110511"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who put the “E” in CPR: Equity before extracorporeal?","authors":"Marcel C.G. van de Poll,&nbsp;Samuel Heuts","doi":"10.1016/j.resuscitation.2025.110519","DOIUrl":"10.1016/j.resuscitation.2025.110519","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110519"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal and neonatal outcomes following resuscitative hysterotomy for out of hospital cardiac arrest: A systematic review","authors":"Caroline Leech ,&nbsp;Tim Nutbeam ,&nbsp;Justin Chu ,&nbsp;Marian Knight ,&nbsp;Kim Hinshaw ,&nbsp;Tracy-Louise Appleyard ,&nbsp;Stephanie Cowan ,&nbsp;Keith Couper ,&nbsp;Joyce Yeung","doi":"10.1016/j.resuscitation.2024.110479","DOIUrl":"10.1016/j.resuscitation.2024.110479","url":null,"abstract":"<div><h3>Objective</h3><div>To examine maternal and neonatal outcomes following Resuscitative Hysterotomy for out of hospital cardiac arrest (OHCA) and to compare with timing from cardiac arrest to delivery.</div></div><div><h3>Methods</h3><div>The review was registered with PROSPERO (CRD42023445064). Studies included pregnant women with out of hospital cardiac arrest and resuscitative hysterotomy performed (in any setting) during cardiac arrest. We searched MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL), from inception to 25th May 2024, restricted to humans. We included randomised controlled trials, observational studies, cases series or case reports. Two reviewers independently assessed study eligibility, extracted study data, and assessed risk of bias using validated tools. Data are summarised in a narrative synthesis.</div></div><div><h3>Results</h3><div>We included 42 publications (one cohort study, three case series and 38 case reports) including a total of 66 women and 68 neonates. Maternal and newborn survival to hospital discharge was 4.5% and 45.0% respectively. The longest duration from collapse to resuscitative hysterotomy for maternal survival with normal neurological function was 29 min and for neonates was 47 min. There were reported neonatal survivors born at 26 weeks gestation with good outcomes. The certainty of evidence was very low due to risk of bias.</div></div><div><h3>Conclusion</h3><div>There are low rates of maternal survival following resuscitative hysterotomy for OHCA. There are documented neonatal survivors after extended periods of maternal resuscitation, and at extremely preterm gestations (&lt;28 weeks). Further prospective research should assess both maternal and neonatal outcomes to better inform future clinical practice.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110479"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of accidental hypothermia in drowning patients with out-of-hospital cardiac arrest: A nationwide registry-based cohort study","authors":"Kasper Bitzer ,&nbsp;Niklas Breindahl ,&nbsp;Benjamin Kelly ,&nbsp;Oliver Beierholm Sørensen ,&nbsp;Monika Laugesen ,&nbsp;Signe Amalie Wolthers ,&nbsp;Stig Nikolaj Fasmer Blomberg ,&nbsp;Jacob Steinmetz ,&nbsp;Sebastian Wiberg ,&nbsp;Helle Collatz Christensen ,&nbsp;Danish Cardiac Arrest Group","doi":"10.1016/j.resuscitation.2024.110486","DOIUrl":"10.1016/j.resuscitation.2024.110486","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to investigate the associations between hypothermia and mortality or poor neurological outcome in a nationwide cohort of drowning patients with out-of-hospital cardiac arrest (OHCA).</div></div><div><h3>Methods</h3><div>This nationwide, registry-based cohort study reported in-hospital data on drowning patients with OHCA following the Utstein Style For Drowning. Drowning patients with OHCA were identified in the Danish Cardiac Arrest Registry from 2016 to 2021. The primary outcome was the rate of mortality or poor neurological outcome (corresponding to a modified Rankin Scale [mRS] score &gt; 3) at 180 days after the drowning incident in patients with OHCA and accidental hypothermia (&lt;35 °C) vs normothermia (≥35 °C).</div></div><div><h3>Results</h3><div>This study identified 118 drowning patients with OHCA and found an increased rate of mRS &gt; 3 at 180 days after the drowning incident in the hypothermic group compared to the normothermic group (74% vs 18%, <em>p</em> &lt; 0.001). The 180-day mortality (mRS = 6) was 69% in the hypothermic group compared to 16% in the normothermic group (<em>p</em> &lt; 0.001). The hypothermic group had higher rates of ongoing CPR at hospital admission (45% vs 7%, <em>p</em> &lt; 0.001), intensive care unit admission (70% vs 41%, <em>p</em> = 0.003), and mechanical ventilation during hospitalisation (78% vs 32%, <em>p</em> &lt; 0.001) compared to the normothermic group.</div></div><div><h3>Conclusion</h3><div>Hypothermic drowning patients with OHCA had a higher risk of mortality or poor neurological outcome at 180 days compared to normothermic drowning patients with OHCA. This association may likely be explained by confounding factors such as prolonged submersion and cardiac arrest. Further research is warranted.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110486"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraosseous and intravenous vascular access during adult cardiac arrest: A systematic review and meta-analysis","authors":"Keith Couper ,&nbsp;Lars W. Andersen ,&nbsp;Ian R. Drennan ,&nbsp;Brian E. Grunau ,&nbsp;Peter J. Kudenchuk ,&nbsp;Ranjit Lall ,&nbsp;Eric J. Lavonas ,&nbsp;Gavin D. Perkins ,&nbsp;Mikael Fink Vallentin ,&nbsp;Asger Granfeldt","doi":"10.1016/j.resuscitation.2024.110481","DOIUrl":"10.1016/j.resuscitation.2024.110481","url":null,"abstract":"<div><h3>Objective</h3><div>To summarise evidence on the clinical effectiveness of initial vascular attempts via the intraosseous route compared to the intravenous route in adult cardiac arrest.</div></div><div><h3>Methods</h3><div>We searched MEDLINE and Embase (OVID platform), the Cochrane library, and the International Clinical Trials Registry Platform from inception to September 4th 2024 for randomised clinical trials comparing the intraosseous route with the intravenous route in adult cardiac arrest. Our primary outcome was 30-day survival. Secondary outcomes included favourable neurological outcome at 30-days/ hospital discharge and return of spontaneous circulation (both any ROSC and sustained ROSC). We performed meta-analyses using a fixed-effect model. We assessed risk of bias using the Cochrane Risk of Bias-2 tool and evidence certainty using the GRADE approach.</div></div><div><h3>Results</h3><div>We included three randomised clinical trials encompassing 9,332 participants with out-of-hospital cardiac arrest.</div><div>Initial attempts via the intraosseous, compared with intravenous, route did not increase the odds of 30-day survival (odds ratio 0.99, 95% confidence interval 0.84–1.17; 9,272 participants; three trials; moderate-certainty evidence) or favourable neurological outcome at 30-days/ hospital discharge (odds ratio 1.07, 95% confidence interval 0.88–1.30; 9,186 participants; three trials; low-certainty evidence). The odds of achieving sustained return of spontaneous circulation were lower in the intraosseous group (odds ratio 0.89, 95% confidence interval 0.80–0.99; 7,518 participants; two trials; moderate-certainty evidence).</div></div><div><h3>Conclusion</h3><div>Initial vascular access attempts via the intraosseous, compared with intravenous, route in adult cardiac arrest did not improve 30-day survival and may reduce the odds of a sustained return of spontaneous circulation.</div></div>","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110481"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Back to life – Defining long term outcomes after prehospital extracorporeal cardiopulmonary resuscitation","authors":"Justyna Swol,&nbsp;Julian Hoffmann","doi":"10.1016/j.resuscitation.2024.110478","DOIUrl":"10.1016/j.resuscitation.2024.110478","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110478"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Cost of out-of-hospital cardiac arrest survivors compared with matched control groups” [Resuscitation 199 (2024) 1–10]","authors":"Lola Qvist Kristensen ,&nbsp;Maurits W. van Tulder ,&nbsp;Hans Eiskjær ,&nbsp;Lotte Sørensen ,&nbsp;Bettina Wulff Risør ,&nbsp;Lisa Gregersen Oestergaard","doi":"10.1016/j.resuscitation.2025.110517","DOIUrl":"10.1016/j.resuscitation.2025.110517","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110517"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aiming for the right pressure! – Clinical impact of recently published research regarding post-cardiac arrest blood pressure thresholds in children","authors":"A. Wordie,&nbsp;K. Mustafa","doi":"10.1016/j.resuscitation.2025.110492","DOIUrl":"10.1016/j.resuscitation.2025.110492","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110492"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142954140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial oxygen centration for preterm infants in the delivery room resuscitation: Is it the time to modify current recommendations?","authors":"Ming-Chou Chiang","doi":"10.1016/j.resuscitation.2025.110503","DOIUrl":"10.1016/j.resuscitation.2025.110503","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110503"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using OpenAI’s Text-to-video Model Sora to Generate Cardiopulmonary Resuscitation Content","authors":"Nino Fijačko,&nbsp;Gregor Štiglic,&nbsp;Maxim Topaz,&nbsp;Robert Greif","doi":"10.1016/j.resuscitation.2024.110484","DOIUrl":"10.1016/j.resuscitation.2024.110484","url":null,"abstract":"","PeriodicalId":21052,"journal":{"name":"Resuscitation","volume":"207 ","pages":"Article 110484"},"PeriodicalIF":6.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142922779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}