Regenerative medicine最新文献

Industry updates from the field of stem cell research and regenerative medicine in August 2024. 2024 年 8 月干细胞研究和再生医学领域的行业动态。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-11-04 DOI: 10.1080/17460751.2024.2418246

Dusko Ilic, Mirjana Liovic

引用次数: 0

Ultrasound-guided injection using leucocyte-rich platelet-rich plasma for treatment of meniscal injuries in a duathlete: a case report. 使用富含白细胞的血小板血浆在超声波引导下注射治疗一名双项全能运动员的半月板损伤：病例报告。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-10-30 DOI: 10.1080/17460751.2024.2418705

Jeimylo C de Castro, Daniel Wang, Paschenelle Celis, Jeffrey Strakowski

引用次数: 0

Influencing factors and repair advancements in rodent models of peripheral nerve regeneration. 周围神经再生啮齿动物模型的影响因素和修复进展。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-10-29 DOI: 10.1080/17460751.2024.2405318

Timothy C Olsen, Jonnby S LaGuardia, David R Chen, Ryan S Lebens, Kelly X Huang, David Milek, Mark Noble, Jonathan I Leckenby

{"title":"Influencing factors and repair advancements in rodent models of peripheral nerve regeneration.","authors":"Timothy C Olsen, Jonnby S LaGuardia, David R Chen, Ryan S Lebens, Kelly X Huang, David Milek, Mark Noble, Jonathan I Leckenby","doi":"10.1080/17460751.2024.2405318","DOIUrl":"10.1080/17460751.2024.2405318","url":null,"abstract":"Peripheral nerve injuries lead to severe functional impairments, with rodent models essential for studying regeneration. This review examines key factors affecting outcomes. Age-related declines, like reduced nerve fiber density and impaired axonal transport of vesicles, hinder recovery. Hormonal differences influence regeneration, with BDNF/trkB critical for testosterone and nerve growth factor for estrogen signaling pathways. Species and strain selection impact outcomes, with C57BL/6 mice and Sprague-Dawley rats exhibiting varying regenerative capacities. Injury models - crush for early regeneration, chronic constriction for neuropathic pain, stretch for traumatic elongation and transection for severe lacerations - provide insights into clinically relevant scenarios. Repair techniques, such as nerve grafts and conduits, show that autografts are the gold standard for gaps over 3 cm, with success influenced by graft type and diameter. Time course analysis highlights crucial early degeneration and regeneration phases within the first month, with functional recovery stabilizing by three to six months. Early intervention optimizes regeneration by reducing scar tissue formation, while later interventions focus on remyelination. Understanding these factors is vital for designing robust preclinical studies and translating research into effective clinical treatments for peripheral nerve injuries.","PeriodicalId":21043,"journal":{"name":"Regenerative medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142522848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracellular vesicles for corneal regeneration: the new frontier. 用于角膜再生的细胞外囊泡：新领域。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-10-18 DOI: 10.1080/17460751.2024.2412510

Keya Jafari, Ashkon Seyed-Safi, Sajjad Ahmad

引用次数: 0

Industry updates from the field of stem cell research and regenerative medicine in July 2024. 2024 年 7 月干细胞研究和再生医学领域的行业动态。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-10-14 DOI: 10.1080/17460751.2024.2402645

Dusko Ilic, Mirjana Liovic

引用次数: 0

Statement of Retraction: The first Stem Cell-Based Tissue-Engineered Organ Replacement: Implications for Regenerative Medicine and Society. 撤回声明：首例基于干细胞的组织工程器官置换术：对再生医学和社会的影响》。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-10-14 DOI: 10.1080/17576180.2024.2413823

引用次数: 0

Regeneration of full thickness common extensor tendon tear after percutaneous microfragmented adipose graft. 经皮微碎脂肪移植后全厚总伸肌腱撕裂的再生。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-10-10 DOI: 10.1080/17460751.2024.2393555

Imran J Siddiqui, Alyssa Ritner, Sanjay Mahadevan, Kyle J Dineen, Roosevelt Desronvilles

{"title":"Regeneration of full thickness common extensor tendon tear after percutaneous microfragmented adipose graft.","authors":"Imran J Siddiqui, Alyssa Ritner, Sanjay Mahadevan, Kyle J Dineen, Roosevelt Desronvilles","doi":"10.1080/17460751.2024.2393555","DOIUrl":"https://doi.org/10.1080/17460751.2024.2393555","url":null,"abstract":"Tennis elbow, also commonly known as lateral epicondylitis or common extensor tendinosis, is a common musculoskeletal injury in the adult population. Currently, the standard treatment regimen prescribed for this injury involves a combination of rest, physical therapy, bracing and anti-inflammatory medications. If refractory to these conservative measures, platelet-rich plasma has been shown effective. However, in the case of full thickness tears, surgery has remained the only treatment option until now. We present a case report of a 56-year-old man with a diagnosis of a left large full thickness tear and rupture with retraction of his common extensor tendon (CET) following a corticosteroid injection. The patient was treated with microfragmented adipose transfer. He was re-evaluated around 7 weeks and again at 15 weeks post-treatment and demonstrated ultrasound evidence of complete bridging and remodeling of his prior full thickness CET tear and resolution of retraction. This case presents a promising option for patients with full thickness CET tears who would like to refrain from or are unable to have surgery. Further research and possible randomized controlled trials are needed to further assess the full efficacy of microfragmented adipose transfer in the treatment of full thickness CET tears.","PeriodicalId":21043,"journal":{"name":"Regenerative medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Towards stem cell therapies for hearing loss: awareness and perspectives of Australian audiologists and their patients. 听力损失的干细胞疗法：澳大利亚听力学家及其患者的认识和观点。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-10-08 DOI: 10.1080/17460751.2024.2402650

Dysiphan Iem, Georgia Carney, Megan Munsie, Bryony A Nayagam

{"title":"Towards stem cell therapies for hearing loss: awareness and perspectives of Australian audiologists and their patients.","authors":"Dysiphan Iem, Georgia Carney, Megan Munsie, Bryony A Nayagam","doi":"10.1080/17460751.2024.2402650","DOIUrl":"10.1080/17460751.2024.2402650","url":null,"abstract":"Aim: Over the last two decades, numerous experimental studies have examined the feasibility of delivering stem cells into the cochlea to restore hearing. While these studies have spawned new cell therapy companies, there is little information on what patients understand or expect from these emerging therapies.Methods: This study sought to understand the awareness and perspectives of Australian audiologists and their adult patients toward stem cell therapies for treating hearing loss.Results: An anonymous survey indicated 91% of patients and 39% of audiologists were unaware of these therapies being developed. Thirty percent of audiologists reported being asked about stem cell therapies for hearing loss, but 70% were not confident answering patient queries about this and were unsure where to gather information. Primary concerns reported by patients were cost (45%) and safety of treatment (42%). Interestingly, 58% of patients were unsure of how this therapy would improve their hearing, yet 25% of these patients expected that their hearing would return to normal.Conclusion: There was strong support for development of educational materials for both patient and clinician. The increasingly important role of audiologists in providing patient counselling was reflected in overwhelming support (from both patient and clinician) for audiologists providing such information.","PeriodicalId":21043,"journal":{"name":"Regenerative medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Industry updates from the field of stem cell research and regenerative medicine in June 2024. 2024 年 6 月干细胞研究和再生医学领域的行业动态。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-09-17 DOI: 10.1080/17460751.2024.2393560

Dusko Ilic, Mirjana Liovic

引用次数: 0

Induced pluripotent stem cell therapies in heart failure treatment: a meta-analysis and systematic review. 诱导多能干细胞疗法在心力衰竭治疗中的应用：荟萃分析和系统综述。

IF 2.4 4区医学

Regenerative medicine Pub Date : 2024-09-12 DOI: 10.1080/17460751.2024.2393558

Duy Cao Phuong Le, Hoa The Bui, Yen Thi Hai Vu, Quan Duy Vo

引用次数: 0