Psychology Research and Behavior Management最新文献

{"title":"Cultural Adaptation and Psychometric Evaluation of the Chinese Version of the Perceived Stress Reactivity Scale.","authors":"Xinlei Qu, Yu Luo, Yuanyi Liu, Xiangcai He, Yu Zhang","doi":"10.2147/PRBM.S508457","DOIUrl":"10.2147/PRBM.S508457","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the cultural adaptation and psychometric properties of the Perceived Stress Reactivity Scale (PSRS) in the Chinese population.</p><p><strong>Methods: </strong>A total of 3560 Chinese participants aged 18-60 years from various provinces and cities in mainland China were included. Sample 1 (n = 3316) was used for CFA, MI, internal consistency, convergent, criterion-related validity, and difference analysis. Sample 2 (n = 244) was employed to evaluate test-retest reliability over a four-week interval.</p><p><strong>Results: </strong>The study validated a robust 23-item, five-factor structure for the Chinese PSRS, demonstrating strong reliability with a Cronbach's α of 0.90 and a test-retest reliability of 0.83. The PSRS and its subscales were significantly correlated with measures of depression, stress, anxiety, and self-efficacy. Strict invariance was observed across gender and age groups (18-40 and 41-60 years). Women and young adults scored higher on the overall scale and most subscales compared with their counterparts.</p><p><strong>Conclusion: </strong>The PSRS is a reliable instrument for assessing perceived stress reactivity within the Chinese population. By validating its cultural adaptation and psychometric properties, this study lays a foundation for its cross-cultural application. The findings contribute to a deeper understanding of perceived stress reactivity differences across gender and age groups and provide practical insights for future interventions and stress management research in the Chinese population.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"375-385"},"PeriodicalIF":2.8,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personality in Type 1 Diabetes and the Impact of Personality Traits on the Effects of Introducing Diabetes Technology.","authors":"Anna Lilja Secher, Mette Andersen Nexø, Erik Lykke Mortensen, Kirsten Nørgaard","doi":"10.2147/PRBM.S492084","DOIUrl":"10.2147/PRBM.S492084","url":null,"abstract":"<p><strong>Aim: </strong>How well new technology is applied to the daily management of type 1 diabetes (T1D) may be highly influenced by personality traits. The number of studies examining how personality traits influence diabetes self-management technologies such as continuous glucose monitoring and carbohydrate counting with automated insulin bolus calculation based on carbohydrate ratios and insulin sensitivity is scarce. Derived from a randomized controlled trial, we aimed to examine the association between personality traits and glycemic and patient-reported outcomes in adults with T1D on multiple daily insulin injections initiating flash glucose monitoring and carbohydrate counting with automated bolus calculation.</p><p><strong>Methods: </strong>Personality trait scores from The Five-Factor Inventory-3 were analyzed in 170 individuals. We assessed baseline (n = 168) and changes (n = 34) in HbA1c, and patient-reported outcomes (validated questionnaires on diabetes distress, diabetes treatment satisfaction, diabetes psychosocial self-efficacy, diabetes quality of life) in bivariate and partial correlation analyses with personality traits (neuroticism, extraversion, openness to experience, agreeableness, and conscientiousness).</p><p><strong>Results: </strong>Adjusted for sex, age, and diabetes debut age, higher agreeableness correlated negatively with baseline HbA1c (partial correlation -0.20, p < 0.05) but positively with HbA1c change over time (0.36, p < 0.05). Higher neuroticism score was associated with higher baseline distress (0.39, p < 0.001) and lower baseline psychosocial self-efficacy (-0.43, p < 0.001), quality of life (-0.32, p < 0.001) and treatment satisfaction (-0.18, p < 0.05).</p><p><strong>Conclusion: </strong>This study confirms that personality traits are associated with glycemia and patient-reported outcomes in adults with T1D. Consequently, tailored diabetes management approaches are likely to enhance overall outcomes, especially when incorporating diabetes technology.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"353-360"},"PeriodicalIF":2.8,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143503871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Physical Exercise on Sleep Quality Among College Students: The Chain Mediating Effects of Perceived Stress and Ruminative Thinking.","authors":"Deyan Liu, Yuge Tian, Min Liu, Shangjian Yang","doi":"10.2147/PRBM.S510207","DOIUrl":"10.2147/PRBM.S510207","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the relationship between physical exercise and sleep quality among college students, focusing on the chain mediating roles of perceived stress and ruminative thinking.</p><p><strong>Participants and methods: </strong>A total of 955 college students completed questionnaires, including the Physical Activity Rating Scale (PARS-3), the Pittsburgh Sleep Quality Index (PSQI), the Perceived Stress Scale (PSS), and the Ruminative Thinking Response Scale (RRS). The PROCESS macro Model 6 and Bootstrap methods were used to analyze the mediating effects of perceived stress and ruminative thinking.</p><p><strong>Results: </strong>(1) Negative correlations were found between physical exercise and sleep quality (r = -0.361, p < 0.01), perceived stress (r = -0.393, p < 0.01), and ruminative thinking (r = -0.503, p < 0.01). Positive correlations existed between sleep quality and perceived stress (r = 0.477, p < 0.01), as well as between sleep quality and ruminative thinking (r = 0.549, p < 0.01), and perceived stress and ruminative thinking (r = 0.550, p < 0.01). (2) Physical exercise significantly impacted college students' sleep quality directly, with an effect size of -0.074. The relative proportion of indirect effects mediated by perceived stress and ruminative thinking was 20.59%, with individual effect sizes of -0.085 and -0.135 respectively, accounting for 23.89% and 37.93% of the total effect. (3) Additionally, there was a chain mediation effect with an effect size of -0.063, representing 17.59% of the total effect.</p><p><strong>Conclusion: </strong>Physical exercise can reduce perceived stress to alleviate ruminative thinking, thereby improving sleep quality. The findings of this study provide a scientific basis for the development of mental health education and intervention strategies in colleges. Colleges should offer diverse physical activities and improve facilities to encourage student participation in exercise. College students should recognize the importance of physical exercise in enhancing sleep quality, actively engage in physical activities, learn psychological adjustment techniques, and cultivate healthy lifestyle habits.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"361-373"},"PeriodicalIF":2.8,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143503889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging Emotional Trauma and Future Success: Integrating Psychological Support and Talent Management to Address the Impact of Childhood Emotional Abuse on University Students [Letter].","authors":"Zehao Wang, Xizhe Wang","doi":"10.2147/PRBM.S515044","DOIUrl":"10.2147/PRBM.S515044","url":null,"abstract":"","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"341-342"},"PeriodicalIF":2.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11844301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Self-Other Overlap Shapes Online Altruism in Adolescents: The Role of Empathy and Moral Identity.","authors":"Zexu Dong, Ruixin Wang, Zhenyu Zhao, Kunhang Xie, Anan Li, Hongge Luo, Lina Li","doi":"10.2147/PRBM.S492811","DOIUrl":"10.2147/PRBM.S492811","url":null,"abstract":"<p><strong>Purpose: </strong>Although adolescent online behavior has become a research hotspot in recent years, most studies focus on the risks in online life, lacking research on positive phenomena online and even more so on the exploration of their internal mechanisms. This study explores the relationship between self-other overlap, empathy, moral identity, and adolescent online altruistic behavior, and discusses whether empathy and moral identity play a serial mediating role between self-other overlap and adolescent online altruistic behavior.</p><p><strong>Patients and methods: </strong>This study conducted a questionnaire survey on 392 adolescents. Descriptive analysis and correlation analysis were performed using SPSS 23.0, and model construction and bias-adjusted bootstrap mediation effect testing were conducted using Mplus 8.3.</p><p><strong>Results: </strong>There were significant positive correlations between self-other overlap, empathy, moral identity and internet altruistic behavior (r=0.168~0.412, all p<0.01). Self-other overlap can directly predict internet altruistic behavior, and can also indirectly predict internet altruistic behavior through chain mediating effects of empathy and moral identity.</p><p><strong>Conclusion: </strong>This study has discovered the internal mechanism by which self-other overlap affects online altruistic behavior, demonstrating that empathy and moral identity play a chain mediating role in this process. This finding can guide people to view the impact of network development more dialectically, calling for a focus on how to leverage the positive effects of the internet rather than simply blaming its negative impacts. It also provides new theoretical basis for guiding adolescents on how to use the internet healthily, contributing to the construction of a more harmonious online environment.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"331-340"},"PeriodicalIF":2.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11844212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Grief of Peer Loss Among Adolescents: A Narrative Review.","authors":"Xiao-Xue Chen, Jing Chen, Bao-Liang Zhong","doi":"10.2147/PRBM.S504117","DOIUrl":"10.2147/PRBM.S504117","url":null,"abstract":"<p><p>Peer death is not uncommon during adolescence. Unlike the loss of family members, grief following the peer loss is often unrecognized and unsupported by society, making it difficult for adolescents to handle their grief. This may result in prolonged and intense reactions, negatively affecting academic performance and physical and mental health. In this article, we review the manifestations of, associated factors with, and interventions for grief after peer loss and discuss unaddressed questions. A literature search was conducted within three electronic databases (Web of Science, PubMed, and ScienceDirect) from January 1, 2014 to December 29, 2024. Finally, 13 English studies focusing on peer loss and grief among adolescents were identified and included. Grief over the death of a friend in adolescents could be intense, lasting up to 8.5 years, with symptoms such as post-traumatic stress disorder and sleep disturbances. The prolonged grief could impair mental health and social functioning. Girls tend to exhibit more complicated grief reactions and experience a longer duration of grief compared to boys. Personality traits also play a critical role: adolescents with high agreeableness tend to recover more quickly, while those with high neuroticism are less resilient. The quality of the friendship with the deceased and exposure to negative information also influence the grief intensity. Raising professional awareness, providing targeted interventions, and establishing effective social support are essential for grief recovery. Significant gaps still remain in understanding adolescent grief following peer loss, particularly in the mechanisms between different factors and grief, and the feasibility and effectiveness of specific treatment plans. Addressing these limitations is essential for advancing theoretical frameworks and developing targeted interventions. This review provides a foundational basis for future research and clinical practices, with the potential to inform therapeutic approaches and interventions that better support the healing and recovery processes of grieving adolescents.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"343-352"},"PeriodicalIF":2.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11844205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of a Predictive Model for Anxiety Trajectories in Patients with Breast Cancer: A Retrospective Study.","authors":"Xia Li, Ben-Kai Wei, Fan Li, Huan-Huan Yan, Jun Shen","doi":"10.2147/PRBM.S501127","DOIUrl":"10.2147/PRBM.S501127","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to develop and validate a predictive model for short-term post-treatment anxiety trajectories in patients with breast cancer, utilizing baseline patient characteristics and initial anxiety scores to inform precise clinical interventions.</p><p><strong>Methods: </strong>Baseline characteristics were collected from 424 patients diagnosed with breast cancer who underwent surgical treatment at our hospital between January 1, 2021, and December 30, 2022. Anxiety levels were assessed using the Self-Rating Anxiety Scale (SAS) scores at admission and at 3-, 6-, 9-, and 12-months post-treatment. Distinct trajectories of SAS score changes were identified and categorized. Variables were screened, and multiple models were developed. The optimal model was identified through comparative analysis, and a nomogram was generated following model simplification.</p><p><strong>Results: </strong>We found three distinct trends in the trajectory of anxiety, but we grouped them into two broad categories: gradual reduction of anxiety and persistent anxiety. LM Model was established by logistic regression, and Model 1 and Model 2 were established by Random Forest (RF) and eXtreme Gradient Boosting (Xgboost) screening variables. The ROC curve areas in the validation set were 0.822 (0.757-0.887), 0.757 (0.680-0.834) and 0.781 (0.710-0.851), respectively. Model comparison, using Net Reclassification Improvement (NRI) and Integrated Discrimination Improvement (IDI), identified the Lm model as optimal, which underwent further simplification and value assignment. Decision Curve Analysis (DCA) and Clinical Impact Curve (CIC) analyses confirmed the superiority of model-based interventions over general interventions.</p><p><strong>Conclusion: </strong>Distinct anxiety trajectories are observed in patients diagnosed with breast cancer during the first 12 months post-treatment. Predictive modeling based on baseline characteristics is feasible although though further research is warranted.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"315-329"},"PeriodicalIF":2.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11840338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic Impact of the Sleep Disorder, Depression and Anxiety on the Cognitive Function in the First-Episode Depressive Patients.","authors":"Wenqiong Zhang, Nan Zhou, Jie Li","doi":"10.2147/PRBM.S489690","DOIUrl":"10.2147/PRBM.S489690","url":null,"abstract":"<p><strong>Background: </strong>Sleep disorder is closely related to depressive and anxious status as well as cognitive symptoms.</p><p><strong>Materials and methods: </strong>A total of 173 cases with the first-episode major depressive disorder (MDD) were involved in this study. The Hamilton Depression Scale (HAMD-17), Hamilton Anxiety Scale (HAMA), Pittsburgh Sleep Quality Index (PSQI), and Repeatable battery for the Assessment of Neuropsychological Status (RBANS) were used to assess the patients. Three visits were set at baseline at the 4^th and the 8^th weeks. Latent Growth Curve Models (LGCM) were used to analyze the changing tendency and correlation between sleep disorder, depression, anxiety status, and cognitive function in patients with MDD.</p><p><strong>Results: </strong>Baseline sleep status in patients with MDD could predict cognitive function (<i>p</i>=0.043) and changes in cognitive function (<i>p</i>=0.016), and changes in depressive symptoms could negatively predict cognitive function (<i>p</i>=0.021). Changes in depressive status negatively predictability of its cognitive function (<i>p</i>=0.005). Changes in sleep status negatively predict cognitive function (<i>p</i>=0.099). Sex, age, educational duration, and nature of work were included in the LGCM. The comparison among the subgroups in the LGCM indicated that these four dimensions showed consistency in dynamic tendency, demonstrating that cognitive function changes with sleep status.</p><p><strong>Conclusion: </strong>The more severe the sleep disorder in patients with first-episode MDD, the more obvious was the damage to cognition. The dynamic impact of sleep quality on cognitive function is positively correlated, and over time, there is an association between the remission speed of depressive or anxiety symptoms and improving the speed of cognitive function in patients with MDD.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"299-314"},"PeriodicalIF":2.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sedentary Behavior and Its Association With Psychological Well-Being and Sleep Quality in Adolescents: Evidence from a Propensity Score Analysis.","authors":"Lirong Zhang, Shaocong Zhao, Shuangyin Zhao, Hua Zheng, Yizhen Ke, Weichen Yang, Mingxing Lei","doi":"10.2147/PRBM.S508382","DOIUrl":"10.2147/PRBM.S508382","url":null,"abstract":"<p><strong>Background: </strong>Sedentary lifestyles among adolescents have been associated with various health concerns, particularly regarding psychological well-being and sleep quality. However, the associative relationship between sedentary behavior and these health outcomes remains unclear. This study aims to clarify the association between sedentary lifestyle and psychological and sleep health among adolescents through propensity scores matching analysis.</p><p><strong>Methods: </strong>A total of 2,846 adolescents from three universities participated in the study. Data on demographics, exercise habits, eating patterns, sedentary behavior, psychological health, sleep health, self-esteem, and social support were collected. A sedentary lifestyle was defined as sitting for more than six hours daily. Psychological health was assessed using the Generalized Anxiety Disorder-7 (GAD-7) scale for anxiety and the Patient Health Questionnaire-9 (PHQ-9) for depression, while sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI). Self-esteem was evaluated with the Self-Esteem Scale (SES), and social support was measured using the Social Support Rating Scale (SSRS). Propensity scores matching analysis was employed to investigate the associative relationship between sedentary lifestyles and the measured outcomes.</p><p><strong>Results: </strong>Prior to propensity scores matching, significant differences were observed in baseline characteristics between participants with and without sedentary lifestyles, including gender (P=0.01), dietary habits (P<0.001), mobile device usage (P<0.001), stress events (P=0.001), physical activity (P<0.001), and chronic diseases (P=0.024). Participants with sedentary lifestyles exhibited higher scores on the GAD-7 (P<0.001), PHQ-9 (P<0.001), and PSQI (P<0.001), along with lower self-esteem (SES, P=0.041) and social support (SSRS, P<0.001) compared to their more active counterparts. Following propensity scores matching, no significant differences in baseline characteristics were found between the two groups (All P>0.282), indicating a successful matching process. Post-matching analysis revealed that individuals with sedentary lifestyles had significantly higher GAD-7 (P=0.002), PHQ-9 (P=0.013), and PSQI scores (P=0.001) than those without sedentary lifestyles, while no significant differences were found in SES (P=0.755) and SSRS (P=0.676).</p><p><strong>Conclusion: </strong>Our findings indicate that a sedentary lifestyle is associated with poorer psychological health and sleep quality among adolescents, even after controlling for various demographic and lifestyle factors. These results underscore the importance of promoting physical activity and reducing sedentary behavior in this population to enhance their overall well-being.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"281-298"},"PeriodicalIF":2.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11814057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Medication Adherence, Internalized Stigma and Social Support Among Outpatients with Major Depressive Disorder in a Malaysian Hospital: A Cross-Sectional Study.","authors":"Rahilah Halim, Manveen Kaur, Sharifah Suziah Syed Mokhtar, Norliza Chemi, Martha Sajatovic, Yee Kee Tan, Ching Sin Siau, Chong Guan Ng","doi":"10.2147/PRBM.S485333","DOIUrl":"10.2147/PRBM.S485333","url":null,"abstract":"<p><strong>Background: </strong>Internalized stigma and medication non-adherence pose significant challenges for treating major depressive disorder (MDD), leading to disability, increased suicide risk, and morbidity. Limited data exists on modifiable factors associated with adherence in lower-resourced settings like Malaysia. This study aimed to investigate poor adherence prevalence and the demographic and clinical factors associated with poor medication adherence among patients with MDD.</p><p><strong>Methods: </strong>This cross-sectional survey recruited participants using universal sampling from a major hospital in Selangor, Malaysia. Participants answered questionnaires consisting of demographic and clinical information (medical history, duration of anti-depressant treatment for MDD, psychiatric ward admission history, and any medication side effects experienced), the Internalized Stigma of Mental Illness Scale (comprising alienation, stereotype, perceived discrimination, and social withdrawal), the Multidimensional Scale of Perceived Social Support (comprising family, friend, and significant other support), and the Malaysia Medication Adherence Assessment Tool. Simple and multiple logistic regression and mediation analyses were conducted.</p><p><strong>Results: </strong>Of the 268 participants (69% female), 57.1% were suboptimally or moderately adherent to their medication. Buddhists (adjusted odds ratio [a<i>OR</i>] = 0.280, 95% <i>CI</i> [0.115, 0.679], <i>p</i> = 0.005), higher family support (a<i>OR</i> = 0.753, 95% <i>CI</i> [0.591, 0.960], <i>p</i> = 0.022), a history of ward admissions (a<i>OR</i> = 3.523, 95% <i>CI</i> [1.537, 8.072], <i>p</i> = 0.003), and higher internalized stigma (a<i>OR</i> = 2.828, 95% <i>CI</i> [1.497, 5.344], <i>p</i> = 0.001) were significantly associated with low/moderate medication adherence. The effect of internalized stigma subdomains (alienation, perceived discrimination, and social withdrawal) on medication adherence were partially mediated by family support.</p><p><strong>Conclusion: </strong>More than half of the participants demonstrated low to moderate medication adherence. Those with higher internalized stigma demonstrated higher odds of low/moderate medication adherence, but this effect was attenuated by family support. Therefore, internalized stigma and family support are important points of consideration when assessing patients with MDD in Malaysia.</p>","PeriodicalId":20954,"journal":{"name":"Psychology Research and Behavior Management","volume":"18 ","pages":"209-223"},"PeriodicalIF":2.8,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11807782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}