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Regenerative Engineering and Translational Medicine最新文献

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Preparation, Characterization, and Surface Modification of Polycaprolactone-Based Nanofibrous Scaffold by Grafting with Collagen for Skin Tissue Engineering 皮肤组织工程用聚己内酯纳米纤维支架的制备、表征及表面改性
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-02-25 DOI: 10.1007/s40883-022-00254-1
Farnaz Sheikhi, M. Khorram, S. Hashemi, Aliakbar Mohammadi, Hamed Peyrovedin
{"title":"Preparation, Characterization, and Surface Modification of Polycaprolactone-Based Nanofibrous Scaffold by Grafting with Collagen for Skin Tissue Engineering","authors":"Farnaz Sheikhi, M. Khorram, S. Hashemi, Aliakbar Mohammadi, Hamed Peyrovedin","doi":"10.1007/s40883-022-00254-1","DOIUrl":"https://doi.org/10.1007/s40883-022-00254-1","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"55 1","pages":"545 - 562"},"PeriodicalIF":2.6,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72852597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Experimental Repairing of the Defect of Rat Full-Thickness Burn with Cell-Engineered Structure 细胞工程结构修复大鼠全层烧伤缺损的实验研究
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-02-09 DOI: 10.1007/s40883-022-00249-y
Linda Mohammadzadeh Boukani, Razie Kheirjou, Rana Ferdowsi Khosroshahi, A. Khosroshahi
{"title":"Experimental Repairing of the Defect of Rat Full-Thickness Burn with Cell-Engineered Structure","authors":"Linda Mohammadzadeh Boukani, Razie Kheirjou, Rana Ferdowsi Khosroshahi, A. Khosroshahi","doi":"10.1007/s40883-022-00249-y","DOIUrl":"https://doi.org/10.1007/s40883-022-00249-y","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"1 1","pages":"1-8"},"PeriodicalIF":2.6,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89700795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Facile Synthesis of Nickel Oxide Nanoparticles Using Rhamnus prinoides Leaf Extract and Evaluation of its Antibacterial Activities 鼠李叶提取物制备氧化镍纳米颗粒及其抗菌活性评价
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-01-27 DOI: 10.1007/s40883-022-00251-4
A. B. Habtemariam, Engidu Bekele
{"title":"Facile Synthesis of Nickel Oxide Nanoparticles Using Rhamnus prinoides Leaf Extract and Evaluation of its Antibacterial Activities","authors":"A. B. Habtemariam, Engidu Bekele","doi":"10.1007/s40883-022-00251-4","DOIUrl":"https://doi.org/10.1007/s40883-022-00251-4","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"48 1","pages":"482-488"},"PeriodicalIF":2.6,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77547201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Bob Nerem’s The Rules of Life 鲍勃·纳里姆的《生活法则》
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-01-25 DOI: 10.1007/s40883-021-00247-6
Andrés J. García
{"title":"Bob Nerem’s The Rules of Life","authors":"Andrés J. García","doi":"10.1007/s40883-021-00247-6","DOIUrl":"https://doi.org/10.1007/s40883-021-00247-6","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"13 1","pages":"504 - 505"},"PeriodicalIF":2.6,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74773158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wharton’s Jelly Mesenchymal Stem Cells on a Novel Aloe Vera-Polycaprolactone (A-PCL) Composite Scaffold in Burns 华顿果冻间充质干细胞在一种新型芦荟-聚己内酯复合支架上用于烧伤
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-01-21 DOI: 10.1007/s40883-021-00241-y
Susan Jehangir, S. Ramesh, M. Thomas, V. Madhuri
{"title":"Wharton’s Jelly Mesenchymal Stem Cells on a Novel Aloe Vera-Polycaprolactone (A-PCL) Composite Scaffold in Burns","authors":"Susan Jehangir, S. Ramesh, M. Thomas, V. Madhuri","doi":"10.1007/s40883-021-00241-y","DOIUrl":"https://doi.org/10.1007/s40883-021-00241-y","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"25 4 1","pages":"437 - 445"},"PeriodicalIF":2.6,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84973567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Non-Invasive Imaging Modalities for Stem Cells Tracking in Osteoarthritis 骨关节炎干细胞追踪的非侵入性成像方式
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-01-17 DOI: 10.21203/rs.3.rs-1237230/v1
Hengameh Dortaj, Ali Akar Alizadeh, N. Azarpira, L. Tayebi
{"title":"Non-Invasive Imaging Modalities for Stem Cells Tracking in Osteoarthritis","authors":"Hengameh Dortaj, Ali Akar Alizadeh, N. Azarpira, L. Tayebi","doi":"10.21203/rs.3.rs-1237230/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-1237230/v1","url":null,"abstract":"\u0000 The administration of stem cells in regenerative medicine has emerged as a potential treatment option for many diseases. The privation of an impressive cure for joint pathologies such as knee osteoarthritis (OA) has increased concern in stem cell (SC)-based therapies. Many questions remain about the survival and biology of SC after transplantation. Current progression in molecular biology and imaging has accredited winsome non-invasive SC monitoring in living subjects. Over time, these methods have been updated to assess the viability and biology of SC transplantation. The use of nanoparticles has become important in many aspects of SCs tracking. Given that different tracking strategies are being used for clinical trials, it is important to choose the best one. In this review, various imaging methods, which were assimilated to monitor the viability and biology of SC after injection in osteoarthritis, were discussed.","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"375 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75130341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HEK293-Conditioned Medium Altered the Expression of Renal Markers WT1, CD2AP, and CDH16 in the Human Adipose Mesenchymal Stem Cells hek293条件培养基改变人脂肪间充质干细胞中肾标志物WT1、CD2AP和CDH16的表达
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-01-11 DOI: 10.1007/s40883-021-00246-7
Z. Fazeli, Zahra Esmaeilizadeh, M. Omrani, S. Ghaderian, M. Rajabibazl
{"title":"HEK293-Conditioned Medium Altered the Expression of Renal Markers WT1, CD2AP, and CDH16 in the Human Adipose Mesenchymal Stem Cells","authors":"Z. Fazeli, Zahra Esmaeilizadeh, M. Omrani, S. Ghaderian, M. Rajabibazl","doi":"10.1007/s40883-021-00246-7","DOIUrl":"https://doi.org/10.1007/s40883-021-00246-7","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"137 1","pages":"1-7"},"PeriodicalIF":2.6,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79077172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronary-Based Right Heart Flap Recellularization by Rat Neonatal Whole Cardiac Cells: a Viable Sheep Cardiac Patch Model for Possible Management of Heart Aneurysm 大鼠新生全心肌细胞冠脉右心脏皮瓣再细胞化:一种可行的绵羊心脏贴片模型，可能用于心脏动脉瘤的治疗
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-01-10 DOI: 10.1007/s40883-021-00238-7
A. Akbarzadeh, S. H. Tafti, S. Sabetkish, Z. Hassannejad, A. Kajbafzadeh
{"title":"Coronary-Based Right Heart Flap Recellularization by Rat Neonatal Whole Cardiac Cells: a Viable Sheep Cardiac Patch Model for Possible Management of Heart Aneurysm","authors":"A. Akbarzadeh, S. H. Tafti, S. Sabetkish, Z. Hassannejad, A. Kajbafzadeh","doi":"10.1007/s40883-021-00238-7","DOIUrl":"https://doi.org/10.1007/s40883-021-00238-7","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"26 10","pages":"1-12"},"PeriodicalIF":2.6,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72425679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Factors Influencing the Therapeutic Potential of the MSC-derived Secretome 影响间质干细胞衍生分泌组治疗潜力的因素
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2022-01-07 DOI: 10.1007/s40883-021-00242-x
A. Chouw, G. Facicilia, C. R. Sartika, A. Faried, T. Milanda
{"title":"Factors Influencing the Therapeutic Potential of the MSC-derived Secretome","authors":"A. Chouw, G. Facicilia, C. R. Sartika, A. Faried, T. Milanda","doi":"10.1007/s40883-021-00242-x","DOIUrl":"https://doi.org/10.1007/s40883-021-00242-x","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"16 1","pages":"1-10"},"PeriodicalIF":2.6,"publicationDate":"2022-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73976970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Clinical Relevance of Pre-Existing and Treatment-Induced Anti-Poly(Ethylene Glycol) Antibodies. 已有的和治疗诱发的抗聚乙二醇抗体的临床意义
IF 2.2
Regenerative Engineering and Translational Medicine Pub Date : 2022-01-01 Epub Date: 2021-03-25 DOI: 10.1007/s40883-021-00198-y
Helena Freire Haddad, Jacqueline A Burke, Evan A Scott, Guillermo A Ameer
{"title":"Clinical Relevance of Pre-Existing and Treatment-Induced Anti-Poly(Ethylene Glycol) Antibodies.","authors":"Helena Freire Haddad, Jacqueline A Burke, Evan A Scott, Guillermo A Ameer","doi":"10.1007/s40883-021-00198-y","DOIUrl":"10.1007/s40883-021-00198-y","url":null,"abstract":"<p><strong>Abstract: </strong>Poly(ethylene glycol) (PEG) is a nontoxic, hydrophilic polymer that is often covalently attached to proteins, drugs, tissues, or materials; a procedure commonly referred to as PEGylation. PEGylation improves solubility, circulation time, and reduces immunogenicity of therapeutic molecules. Currently, there are 21 PEGylated drugs approved by the Food and Drug Administration (FDA), and more in the developmental stage. In addition to the polymer's applications in the clinic, PEG is widely used as a solvent and emulsifying agent in the formulation of cosmetics, cleaning, and personal care products. Due to the ubiquitous presence of the polymer in everyday products, patients can develop antibodies against PEG (αPEG Abs) that can be problematic when a PEGylated drug is administered. These αPEG Abs can provoke hypersensitivity reactions, accelerated drug clearance, and decreased therapeutic efficacy. Herein, we review how the prevalence of PEG in everyday products has induced αPEG Abs within the general public as well as the effect of these Abs on the performance of PEGylated therapeutics. We will focus on clinical manifestations following the administration of PEGylated drugs.</p><p><strong>Lay summary: </strong>Poly(ethylene glycol) (PEG) is a polymer found in products including cosmetics, personal care products, cleaning agents, medicine, and food. Due to the prevalence of PEG, people can develop antibodies (αPEG Abs) against the polymer, which recognize PEG as foreign. Of note, PEG is frequently incorporated into drug formulations to improve therapeutic efficacy. Complications can arise when a patient receiving a PEGylated drug has previously developed αPEG Abs from interactions with PEG in everyday products. The presence of high concentrations of αPEG Abs in blood can result in decreased treatment efficacy and allergic reactions to a wide range of therapeutics.</p>","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"8 1","pages":"32-42"},"PeriodicalIF":2.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25532516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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