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The Role of Nanomaterials and Biological Agents on Rotator Cuff Regeneration. 纳米材料和生物制剂在肩袖再生中的作用。
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-12-01 Epub Date: 2020-09-23 DOI: 10.1007/s40883-020-00171-1
Kenyatta S Washington, Nikoo Saveh Shemshaki, Cato T Laurencin
{"title":"The Role of Nanomaterials and Biological Agents on Rotator Cuff Regeneration.","authors":"Kenyatta S Washington,&nbsp;Nikoo Saveh Shemshaki,&nbsp;Cato T Laurencin","doi":"10.1007/s40883-020-00171-1","DOIUrl":"https://doi.org/10.1007/s40883-020-00171-1","url":null,"abstract":"<p><p>The rotator cuff is a musculotendon unit responsible for movement in the shoulder. Rotator cuff tears represent a significant number of musculoskeletal injuries in the adult population. In addition, there is a high incidence of retear rates due to various complications within the complex anatomical structure and the lack of proper healing. Current clinical strategies for rotator cuff augmentation include surgical intervention with autograft tissue grafts and beneficial impacts have been shown, but challenges still exist because of limited supply. For decades, nanomaterials have been engineered for the repair of various tissue and organ systems. This review article provides a thorough summary of the role nanomaterials, stem cells and biological agents have played in rotator cuff repair to date and offers input on next generation approaches for regenerating this tissue.</p>","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"7 4","pages":"440-449"},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40883-020-00171-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39802555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Ligament Regenerative Engineering: Braiding Scalable and Tunable Bioengineered Ligaments Using a Bench-Top Braiding Machine. 韧带再生工程：使用台式编织机编织可扩展和可调节的生物工程韧带。
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-12-01 Epub Date: 2020-10-06 DOI: 10.1007/s40883-020-00178-8
Paulos Y Mengsteab, Joseph Freeman, Mohammed A Barajaa, Lakshmi S Nair, Cato T Laurencin
{"title":"Ligament Regenerative Engineering: Braiding Scalable and Tunable Bioengineered Ligaments Using a Bench-Top Braiding Machine.","authors":"Paulos Y Mengsteab, Joseph Freeman, Mohammed A Barajaa, Lakshmi S Nair, Cato T Laurencin","doi":"10.1007/s40883-020-00178-8","DOIUrl":"10.1007/s40883-020-00178-8","url":null,"abstract":"<p><p>Anterior cruciate ligament (ACL) injuries are common sports injuries that typically require surgical intervention. Autografts and allografts are used to replace damaged ligaments. The drawbacks of autografts and allografts, which include donor site morbidity and variability in quality, have spurred research in the development of bioengineered ligaments. Herein, the design and development of a cost-effective bench-top 3D braiding machine that fabricates scalable and tunable bioengineered ligaments is described. It was demonstrated that braiding angle and picks per inch can be controlled with the bench-top braiding machine. Pore sizes within the reported range needed for vascularization and bone regeneration are demonstrated. By considering a one-to-one linear relationship between cross-sectional area and peak load, the bench-top braiding machine can theoretically fabricate bioengineered ligaments with a peak load that is 9× greater than the human ACL. This bench-top braiding machine is generalizable to all types of yarns and may be used for regenerative engineering applications.</p>","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"7 4","pages":"524-532"},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734580/pdf/nihms-1635563.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39802556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Review of Biological Augmentation for Rotator Cuff Repair: a Single Laboratory’s History 回顾生物增强肩袖修复:单一实验室的历史
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-11-29 DOI: 10.1007/s40883-021-00240-z
Bennett E. Propp, C. Uyeki, Michael R. Mancini, Benjamin C. Hawthorne, M. Mccarthy, A. Mazzocca
{"title":"A Review of Biological Augmentation for Rotator Cuff Repair: a Single Laboratory’s History","authors":"Bennett E. Propp, C. Uyeki, Michael R. Mancini, Benjamin C. Hawthorne, M. Mccarthy, A. Mazzocca","doi":"10.1007/s40883-021-00240-z","DOIUrl":"https://doi.org/10.1007/s40883-021-00240-z","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"22 1","pages":"377 - 383"},"PeriodicalIF":2.6,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81625856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Iranian National Guideline for Cell Therapy and Regenerative Medicine 伊朗国家细胞治疗和再生医学指南
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-11-05 DOI: 10.1007/s40883-021-00239-6
J. Verdi, Mahdi Shadnoush, G. Janbabai, Alireza Shoae-Hassani, Seyed Abdolreza Mortazavi-Tabatabei, Iman Seyhoun, S. Sharif
{"title":"The Iranian National Guideline for Cell Therapy and Regenerative Medicine","authors":"J. Verdi, Mahdi Shadnoush, G. Janbabai, Alireza Shoae-Hassani, Seyed Abdolreza Mortazavi-Tabatabei, Iman Seyhoun, S. Sharif","doi":"10.1007/s40883-021-00239-6","DOIUrl":"https://doi.org/10.1007/s40883-021-00239-6","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"27 1","pages":"370 - 376"},"PeriodicalIF":2.6,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83187820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Status of Stem Cell Therapy and Nanofibrous Scaffolds in Cardiovascular Tissue Engineering 干细胞治疗和纳米纤维支架在心血管组织工程中的研究现状
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-10-26 DOI: 10.1007/s40883-021-00230-1
Aliakbar Yousefi-Ahmadipour, Fatemeh Asadi, Ali Pirsadeghi, N. Nazeri, R. Vahidi, M. Abazari, Ali Afgar, Mohamad Javad Mirzaei-Parsa
{"title":"Current Status of Stem Cell Therapy and Nanofibrous Scaffolds in Cardiovascular Tissue Engineering","authors":"Aliakbar Yousefi-Ahmadipour, Fatemeh Asadi, Ali Pirsadeghi, N. Nazeri, R. Vahidi, M. Abazari, Ali Afgar, Mohamad Javad Mirzaei-Parsa","doi":"10.1007/s40883-021-00230-1","DOIUrl":"https://doi.org/10.1007/s40883-021-00230-1","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"194 1","pages":"248 - 268"},"PeriodicalIF":2.6,"publicationDate":"2021-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75026214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
News and Views December 2021 新闻与观点2021年12月
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-10-13 DOI: 10.1007/s40883-021-00235-w
Bernard Gordon, L. Griffith
{"title":"News and Views December 2021","authors":"Bernard Gordon, L. Griffith","doi":"10.1007/s40883-021-00235-w","DOIUrl":"https://doi.org/10.1007/s40883-021-00235-w","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"61 1","pages":"556-558"},"PeriodicalIF":2.6,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82893608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and Characterization of Maltose-Conjugated Polycaprolactone Nanofibrous Scaffolds for Uterine Tissue Engineering 用于子宫组织工程的麦芽糖共轭聚己内酯纳米纤维支架的设计与表征
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-10-01 DOI: 10.1007/s40883-021-00231-0
Srividya Hanuman, M. Nune
{"title":"Design and Characterization of Maltose-Conjugated Polycaprolactone Nanofibrous Scaffolds for Uterine Tissue Engineering","authors":"Srividya Hanuman, M. Nune","doi":"10.1007/s40883-021-00231-0","DOIUrl":"https://doi.org/10.1007/s40883-021-00231-0","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"11 1","pages":"334-344"},"PeriodicalIF":2.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73497203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Green Synthesis, Characterization, and Application of Ascophyllum Nodosum Silver Nanoparticles 藤茎银纳米颗粒的绿色合成、表征及应用
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-09-29 DOI: 10.21203/rs.3.rs-944036/v1
S. K. Mishra, Saket Sinha, Ashutosh Kumar Singh, P. Upadhyay, Diya Kalra, P. Kumar, K. Tiwari, R. Singh, R. Singh, Arvind Kumar, Alok M. Tripathi
{"title":"Green Synthesis, Characterization, and Application of Ascophyllum Nodosum Silver Nanoparticles","authors":"S. K. Mishra, Saket Sinha, Ashutosh Kumar Singh, P. Upadhyay, Diya Kalra, P. Kumar, K. Tiwari, R. Singh, R. Singh, Arvind Kumar, Alok M. Tripathi","doi":"10.21203/rs.3.rs-944036/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-944036/v1","url":null,"abstract":"Purpose Green nanotechnology as a field has emerged and gained popularity amongst biologists due to its cost-effective and environment-friendly advancements. The most preferred is the biological method which involves plants and their extracts. Methods The silver nanoparticles were synthesized by a sunlight-driven aqueous extract (AE) of whole plant powder of Ascophyllum nodosum . Advanced techniques like high-resolution scanning electron microscopy (HRSEM), energy dispersive X-ray (EDX), high-resolution transmission electron microscopy (HRTEM), and particle size analysis were used to determine the nature of nanoparticles. Antioxidant, anti-fungal, and anti-leishmanial activities were evaluated. Result The techniques confirmed the formation of spherical particles of the desired range of size. Silver nanoparticles exhibited a much greater DPPH (2,2-diphenyl-1-picryl-hydrazine-hydrate) radical scavenging activity which was almost six to seven folds more than that exhibited by the AE alone. The anti-leishmanial and cytotoxic activities were evaluated on Leishmania donovani promastigote and amastigote. Conclusion The synthesized AgNPs showed remarkable DPPH radical scavenging ability owing to their antioxidant properties. The anti-leishmanial activity was exceptionally viable in both AE and AgNPs. The findings all together support the tendency of Ascophyllum nodosum to efficiently synthesized AgNPs which could be utilized for its anti-leishmanial properties. Graphical Abstract","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"29 1 1","pages":"1-15"},"PeriodicalIF":2.6,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91069817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Evaluation of Microfluidic Approaches to Encapsulate Cells into PEGDA Microparticles 微流体将细胞包封成PEGDA微粒的方法的评价
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-09-28 DOI: 10.1007/s40883-021-00232-z
Kristopher A. White, Rabab Chalaby, Ronke M. Olabisi
{"title":"Evaluation of Microfluidic Approaches to Encapsulate Cells into PEGDA Microparticles","authors":"Kristopher A. White, Rabab Chalaby, Ronke M. Olabisi","doi":"10.1007/s40883-021-00232-z","DOIUrl":"https://doi.org/10.1007/s40883-021-00232-z","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"15 1","pages":"345-354"},"PeriodicalIF":2.6,"publicationDate":"2021-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85383925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Regenerative Engineering Approaches to Scar-Free Skin Regeneration 无疤痕皮肤再生的再生工程方法
IF 2.6
Regenerative Engineering and Translational Medicine Pub Date : 2021-09-24 DOI: 10.1007/s40883-021-00229-8
T. Otsuka, H. Kan, C. Laurencin
{"title":"Regenerative Engineering Approaches to Scar-Free Skin Regeneration","authors":"T. Otsuka, H. Kan, C. Laurencin","doi":"10.1007/s40883-021-00229-8","DOIUrl":"https://doi.org/10.1007/s40883-021-00229-8","url":null,"abstract":"","PeriodicalId":20936,"journal":{"name":"Regenerative Engineering and Translational Medicine","volume":"78 1","pages":"225 - 247"},"PeriodicalIF":2.6,"publicationDate":"2021-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81210462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
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