Reactive & Functional Polymers最新文献

{"title":"Advances and prospects in Alzheimer's disease diagnosis and treatment using MOFs and COFs: Mechanism and AI-assisted strategies","authors":"Fenglan Liang ,&nbsp;Jie Li ,&nbsp;Yingzi Feng ,&nbsp;Yanlong Zhou ,&nbsp;Liang Cao ,&nbsp;Daniel Omoding ,&nbsp;Madhav Raj Jayswal ,&nbsp;Abhinav Kumar ,&nbsp;Zhenjun Song ,&nbsp;Jun Wang ,&nbsp;Ying Pan","doi":"10.1016/j.reactfunctpolym.2025.106601","DOIUrl":"10.1016/j.reactfunctpolym.2025.106601","url":null,"abstract":"<div><div>Alzheimer's disease (AD) is a common central nervous system neurodegenerative disorder, with its diagnosis and treatment posing significant challenges in the field of neurodegenerative diseases. With the rising global incidence of AD, there is growing interest in nanomaterials that enable precise and efficient diagnosis and treatment of the disease. In particular, the early diagnosis and targeted therapy of AD have long been hindered by issues such as low sensitivity in biomarker detection, poor blood-brain barrier (BBB) penetration, and the complexity of pathological mechanisms, making effective diagnosis and treatment difficult. Consequently, novel approaches are needed to address these challenges. Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), owing to their high surface area, customizable structures, and excellent biocompatibility, demonstrate outstanding potential in ultra-sensitive biomarker detection, targeted drug delivery and controlled release, and AI-enhanced synergistic diagnosis and treatment for AD. This review focuses on the urgent needs in AD diagnosis and therapy, summarizing its pathogenesis, current diagnostic methods, and treatment status. It highlights the innovative roles of two porous nanomaterials, MOFs and COFs, across the entire process of “early diagnosis-targeted therapy-intelligent optimization” and elucidates their practical efficacy in AD management. Additionally, it explores the integration strategies of these materials with artificial intelligence (AI) and machine learning (ML) technologies. Finally, the review concludes by discussing the challenges and future prospects of MOFs and COFs as potential diagnostic and therapeutic systems for AD.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106601"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biointerfacial characteristics between macrophage cells and biocompatible hydrogels: Cell colonization capacity of 3D scaffolds","authors":"Rocio Bonino ,&nbsp;Virginia Capella ,&nbsp;Nahir Panozzo Lacunza ,&nbsp;Martin Broglia ,&nbsp;Cesar Barbero ,&nbsp;Pablo Bosch ,&nbsp;Nancy Rodriguez ,&nbsp;Ana C. Liaudat ,&nbsp;Claudia R. Rivarola","doi":"10.1016/j.reactfunctpolym.2025.106560","DOIUrl":"10.1016/j.reactfunctpolym.2025.106560","url":null,"abstract":"<div><div>Soft synthetic materials based on hydrogels with adequate biointerfacial properties to interact with living systems are being developed for biomedical applications. Macrophage cells exposed to synthetic materials play a fundamental role in indicating if an inflammation process is initiated. To propose new hydrogels such as cell scaffolds, the biointerfacial properties, biocompatibility and immune response of murine (RAW 264.7) and bovine (BoMac) macrophage cells exposed to hydrogels of different chemical composition are analysed. The hydrogels based on N-isopropylacrylamide (NIPAM) and copolymerized with cationic ((3-(acrylamidopropyl) trimethylammonium chloride, APTA), anionic (2-acrylamidopropane sulfonic acid, AMPS), and neutral (N-Tris((hydroxymethyl)methyl) acrylamide, THMA) comonomers are synthesized by cryopolymerization at −18 °C and room temperature (∼25 °C). Interfacial properties of hydrogels in culture medium regarded to water are valued by swelling capacity, volume phase transition temperature (VPTT), and contact angles. Only PNIPAM and PNIPAM-co-3 %APTA hydrogels are biocompatible against macrophage cells, showing a process of adaptation without causing cellular damage or significant immune response. Then, the <em>in vitro</em> cell migration assays are carried out with both macroporous hydrogels. Cell scraping (or wound) technique demonstrates that cells faster colonize the 3D hydrogels than the negative (without hydrogel) and positive (<em>E. coli</em> homogenate) control systems. Therefore, macroporosity and biointerfacial characteristics of these materials are adequate as scaffolds to induce the 3D tissue regenerative and promote wound healing as a new biomedical treatment.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106560"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rational design of phenol-functionalized mixed-shell polymer particles for tailored antioxidant pickering emulsions as an enzymatic microreactor","authors":"Xinyi Wu ,&nbsp;Siqi Zhu ,&nbsp;Siqi Zheng ,&nbsp;Guoxiang Wang ,&nbsp;Yong Gao","doi":"10.1016/j.reactfunctpolym.2025.106574","DOIUrl":"10.1016/j.reactfunctpolym.2025.106574","url":null,"abstract":"<div><div>The preparation of antioxidant Pickering emulsions and their application as enzymatic reaction platform for the ester hydrolysis were indicated in this study. Mixed shell polymer particles (MSPPs), exhibiting a homogeneous poly(styrene-<em>alt</em>-maleic anhydride) core and mixed poly (oligo(ethylene glycol) methyl ether methacrylate/polystyrene shells, were first synthesized <em>via</em> one-pot RAFT mediated polymerization induced self-assembly strategy, which were further functionalized with <em>p</em>-aminophenol (PAP). The resulting functionalized MSPPs exhibited both outstanding interfacial activity and excellent antioxidant capacity, which were then used as Pickering emulsifiers to prepare antioxidant lipase-containing water-in-toluene Pickering emulsions through hand-shaking emulsification. The generated Pickering emulsions were subsequently applied as enzymatic microreactors for the hydrolysis of <em>p</em>-nitrophenyl butyrate. The catalytic performances of the fabricated microreactors were investigated. A strong positive correlation between the antioxidant capability of Pickering emulsions and the enhanced long-term catalytic performance of the enzymatic microreactors was revealed in this study.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106574"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication of high-performance butadiene-styrene copolymer thermosets co-cured by reactive liquid crystalline poly(ester imide)","authors":"Xiangyi Li ,&nbsp;Yuanqin Guo ,&nbsp;Shumei Liu ,&nbsp;Jianqing Zhao","doi":"10.1016/j.reactfunctpolym.2025.106567","DOIUrl":"10.1016/j.reactfunctpolym.2025.106567","url":null,"abstract":"<div><div>Butadiene-styrene copolymer (BSC) resin is one of the hydrocarbon-based resins, which are regarded as promising candidates for high-frequency electronic packaging applications due to their inherently excellent dielectric properties. However, the insufficient mechanical and thermal performance of BSC, particularly the high coefficient of thermal expansion (CTE), adversely affects its reliability and dimensional stability, thereby limiting its potential and wider applications. In contrast, liquid crystalline poly(ester imide)s (LCPEIs) exhibit molecular orientation and possess a rigid, heat-resistant ester-imide backbone, resulting in excellent thermal, mechanical, and dielectric properties. Nevertheless, the high cost and complex synthesis of LCPEIs are considered major barriers to their widespread practical application. Although LCPEIs and BSC exhibit complementary properties, it is difficult to obtain high-performance blends through simple physical blending because of their inherent incompatibility. In order to solve this problem, a low-molecular-weight LCPEI bearing reactive vinyl groups was synthesized and used for co-curing butadiene-styrene copolymer (BSC) resin to obtain LCPEI/BSC thermosets. The incorporation of rigid segments and the formation of a denser cross-linked network endowed the LCPEI/BSC thermosets with markedly improved mechanical and thermal performance. At a loading of 4.8 wt% LCPEI, the resulting LCPEI-5/BSC thermoset exhibited a 33 % increase in Young's modulus and a 38 % increase in tensile strength, along with a 31 % reduction in CTE, compared to the BSC thermoset. This work demonstrates a feasible strategy to enhance the mechanical and thermal properties of LCPEI/BSC thermosets by co-curing the reaction of LCPEI for the potential application in advanced electronic packaging.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106567"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient synthesis of PMMA in green solvents of choline chloride and glycerol-based deep eutectic solvents","authors":"Rawda Maen Sunoqrot ,&nbsp;Putri Nur Amelina Muhammad Shamsudin Ng ,&nbsp;Amjad Abedelqader ,&nbsp;Hesham Ali Metwally Ali El-enshasy ,&nbsp;Mohamad Hamdi Zainal Abidin ,&nbsp;Chen Qian ,&nbsp;Naharullah Jamaluddin","doi":"10.1016/j.reactfunctpolym.2025.106581","DOIUrl":"10.1016/j.reactfunctpolym.2025.106581","url":null,"abstract":"<div><div>Polymethyl methacrylate (PMMA) is a widely utilized thermoplastic in electronic applications, packaging, and biomedical devices. However, conventional PMMA is synthesized in volatile organic solvents such as toluene, significantly impacting the environment. This issue needs an urgent alternative to minimize the toxicity of organic solvents. Herein, this study reports the synthesis of PMMA in choline chloride and Glycerol-based DES (ChCl/Gly DES) via free radical polymerization (FRP), as there is significantly less work done using fashionable and environmentally friendly DESs in the synthesis of PMMA. This DES enhances the polymerization performance through stabilizing the monomer and initiator via hydrogen bonding. A 50:50 wt% ratio of MMA to DES with 0.5 wt% APS at 60 °C for 6 h yielded the highest monomer conversion of 99.5 %. A comprehensive characterization using ¹H NMR, FTIR, DSC, TGA, and GPC was conducted to evaluate the polymer performance. Results revealed a high molecular weight polymer of 246,518 g/mol with a notably high glass transition (T_g) of 123.2 °C. FTIR confirmed the hydrogen bonding formed between PMMA and DES, contributing to the high thermal stability and reduced brittleness. The involvement of DES lowered activation energy (Ea = 23.3 kJ/mol) compared to the conventional solvents, and exhibited a higher apparent rate constant (0.883 h⁻¹). These findings highlight ChCl/Gly DES as a green alternative to organic solvents and also its capability in producing an efficient PMMA-DES.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106581"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145681845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pH-responsive hydrogel formed by chitosan and protocatechualdehyde via Schiff base for antioxidant and antibacterial application","authors":"Tongtong Zhang,&nbsp;Yawei Chen,&nbsp;Yiting Cao,&nbsp;Jindie Yuan,&nbsp;Xianjun Tang,&nbsp;Huiyun Zhou","doi":"10.1016/j.reactfunctpolym.2025.106561","DOIUrl":"10.1016/j.reactfunctpolym.2025.106561","url":null,"abstract":"<div><div>To address the global challenge of antibiotic overuse, alternative strategies including inorganic nanoparticles, photothermal therapy, and photodynamic therapy have been developed in recent years. However, their clinical translation has been hindered by complicated manufacturing processes and high production costs. This study successfully developed a pH-responsive chitosan-based hydrogel via an environmentally friendly Schiff base reaction, leveraging the dual inherent antibacterial and antioxidant properties of both chitosan (CS) and protocatechualdehyde (PA). The chitosan-protocatechualdehyde (CS-PA) hydrogel exhibited superior swelling capacity, excellent injectability, and potent antioxidant and antibacterial activities. Antibacterial experiments demonstrated that the CS-PA hydrogel significantly inhibited the growth of <em>Escherichia coli</em> (<em>E. coli</em>) and <em>Staphylococcus aureus</em> (<em>S. aureus</em>), with the CS-PA200 hydrogel achieving complete inhibition of both bacteria within 24 h. These results establish the CS-PA hydrogel as a clinically promising, antibiotic-free platform for combating drug-resistant infections while promoting wound regeneration.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106561"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145546762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sulfated polysaccharides and their potential applications as drug carrier systems: A review","authors":"Sakthivel Ragul,&nbsp;Sreeram Sneha,&nbsp;Shivanshu Nautiyal,&nbsp;Akshad Balde,&nbsp;Rasool Abdul Nazeer","doi":"10.1016/j.reactfunctpolym.2025.106576","DOIUrl":"10.1016/j.reactfunctpolym.2025.106576","url":null,"abstract":"<div><div>Sulfated polysaccharides are either naturally occurring biopolymers derived primarily from marine algae and some terrestrial sources or synthesized chemically. These macromolecules have gained increasing attention in biomedical science due to their unique structural properties, biocompatibility, biodegradability, and diverse biological activities. In particular, their application as drug carriers in various delivery systems has opened new avenues in targeted and sustained drug release. Owing to the presence of sulfate groups, these polysaccharides exhibit strong interactions with drugs, proteins, and cell membranes, enabling enhanced bioavailability, mucoadhesive properties, and site-specific delivery. Their therapeutic roles span across wound healing, anti-inflammatory action, cancer therapy, and regenerative medicine. The present work provides a comprehensive analysis of the major types of sulfated polysaccharides, including thiolated chitosan, carrageenan, chondroitin sulfate, alginate sulfate, ulvan, and fucoidans. Each polysaccharide is discussed with respect to its structural characteristics, drug-binding potential, and utility in various delivery platforms such as nanoparticles, hydrogels, micelles, and scaffolds. The discussion further emphasizes commercially available formulations, outlining their advantages in enhancing drug stability, prolonging retention time, and improving therapeutic outcomes. Despite their promising biomedical properties, most applications of sulfated polysaccharides remain confined to in vitro studies, with limited in vivo and clinical data. Thus, further research is required to explore their pharmacokinetics, safety, and efficacy in biological systems. The primary focus of this review is to consolidate current knowledge on sulfated polysaccharides as drug carriers, evaluate their biological significance, and identify gaps and future directions for their development in advanced drug delivery systems.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106576"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deodorizing mechanism of adhesive foam sheet containing cellulose nanofibers against hydrogen sulfide gas","authors":"Atsushi Sone ,&nbsp;Akira Isogai","doi":"10.1016/j.reactfunctpolym.2025.106579","DOIUrl":"10.1016/j.reactfunctpolym.2025.106579","url":null,"abstract":"<div><div>An aqueous dispersion of TEMPO-oxidized cellulose nanofibers with copper carboxylate groups (TOCN-Cu) (TEMPO: 2,2,6,6-tetramethylpiperidine-1-oxyl radical) and a rubber latex were mixed. This mixture was then coated onto an opaque polypropylene (PP) or transparent poly(ethylene terephthalate) (PET) film and thermally dried to prepare a TOCN-Cu-containing foam rubber layer on the PP or PET film. The foam rubber side of each sheet was adhered to a glass plate using pressure, which was then placed in a test bag. The adsorption of odorous H₂S on each glass plate/TOCN-Cu-containing foam rubber/film was evaluated by determining the H₂S gas concentration in the test bag against the treatment time, which had a length of up to 317 days. The H₂S gas penetrated from the edge of each composite sheet and reached the interior, forming CuS, which was homogeneously distributed throughout the foam rubber layer through its continuously connected pore. The TOCN-Cu was primarily present near the rubber/air interface in the foam layer of the composite adhesive sheet, resulting in excellent deodorizing functions. However, H₂S gas was mostly adsorbed to the TOCN-Cu-containing foam rubber sheets by physical interactions. This is because the S/Cu molar ratio for a representative H₂S-adsorbed sheet was calculated to be ∼2080.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106579"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of polyalumino-titanocarbonsilane from a commercial polycarbosilane","authors":"Xiaohong Li ,&nbsp;Cai Ye ,&nbsp;Jianjun Chen ,&nbsp;Zahoor Ahmad","doi":"10.1016/j.reactfunctpolym.2025.106600","DOIUrl":"10.1016/j.reactfunctpolym.2025.106600","url":null,"abstract":"<div><div>In this work, a novel polyalumino-titanocarbonsilane (PATCS) was synthesized by the reaction of commercial spinning grade polycarbosilane (PCS) with aluminum acetylacetonate (Al(AcAc)₃) and titanocene dichloride (Ti(C₅H₅)₂Cl₂). A dense SiC ceramic fiber was obtained by melt-spinning, thermal oxidation curing in relatively short curing time (∼ 1 h) at 473 K, and pyrolysis of the PATCS. To reveal the thermal polymerization mechanisms of PATCS, the as-synthesized PATCS were investigated by FT-IR, XPS, GPC, ²⁹Si NMR, TG, rotary rheometer, metaloscope. The results showed that the PATCS was consisted of Si<img>H bonds, Si-CH₃ groups, Si-CH₂-Si groups, and a small amount of Si<img>O bonds and C<img>C bonds. The polymerization mechanism of PATCS involves the reactions of Si<img>H bonds in polycarbosilane (PCS) with Ti<img>Cl, C<img>C, and Al-O-R groups to form Si<img>Ti, Si-C-C, Si-C-Ti, and Si-O-Al bonds. The TGA results showed that mass residual rate under high temperature had an obviously increase with adding Al(AcAc)₃ and Ti(C₅H₅)₂Cl₂. The PCS, PACS and PATCS were pseudoplastic fluid and their viscosity decreased with rising temperature. Suitable melt-spinning temperature range of the PATCS-1 was 553–593 K. A continuous PATCS-1 fiber with a diameter of 29.33 ± 2.99 μm was obtained by the melt-spinning process at 553 K. The Ti element and C<img>C bonds in PATCS might accelerate the curing of the PATCS fibers in air. The study provides a facile synthetic method for preparing a novel precursor polymer, which serves as a precursor for high-performance double-metal heterogeneous element-containing SiC ceramic fiber and can be efficiently cured in air.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106600"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145737468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-elastic, anti-shrinkage poly(butylene adipate-co-terephthalate) foams prepared by ultraviolet-induced chain extension strategy","authors":"Fu-Lu Chang ,&nbsp;Lun Chen ,&nbsp;Zi-Yang Hua ,&nbsp;Sheng Wang ,&nbsp;Xiao-Chun Yin ,&nbsp;Xian-Wu Cao ,&nbsp;Guang-Jian He","doi":"10.1016/j.reactfunctpolym.2025.106556","DOIUrl":"10.1016/j.reactfunctpolym.2025.106556","url":null,"abstract":"<div><div>Biodegradable polybutylene adipate-terephthalate (PBAT) foams have garnered significant attention as environmental and energy concerns escalate. However, PBAT foams produced via supercritical carbon dioxide (scCO₂) foaming often suffer from severe shrinkage, limiting their practical applications. Herein, we developed a novel strategy to address this issue by fabricating long chain branched PBAT through UV-induced reactive extrusion. Glycidyl methacrylate (GMA) and trimethylolpropane tri-acrylate (TMPTA) were introduced to induce branching via epoxy groups and carbon‑carbon double bonds during PBAT processing, respectively. The formation of long chain branched structures was confirmed through rheological analysis and Fourier transform infrared (FTIR) spectroscopy. The incorporation of branched structures significantly enhanced the melt strength and rheological properties of PBAT, thereby mitigating foam shrinkage. The modified PBAT foams exhibited an impressive expansion ratio of 10.4 without shrinkage, while maintaining a uniform cell structure with an average size below 40 μm under optimized conditions (15 MPa, 100 °C). Ultraviolet-induced chain extension strategy plays a pivotal role in enhancing CO₂ foamability and dimensional stability, offering a widely applicable anti-shrinkage strategies in biodegradable polymers.</div></div>","PeriodicalId":20916,"journal":{"name":"Reactive & Functional Polymers","volume":"219 ","pages":"Article 106556"},"PeriodicalIF":5.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145570776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}