RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.240982
Jacob Sosna, Leo Joskowicz, Mor Saban
{"title":"Navigating the AI Landscape in Medical Imaging: A Critical Analysis of Technologies, Implementation, and Implications.","authors":"Jacob Sosna, Leo Joskowicz, Mor Saban","doi":"10.1148/radiol.240982","DOIUrl":"10.1148/radiol.240982","url":null,"abstract":"<p><p>The growing volume and complexity of medical imaging outpaces the available radiologist workforce, risking timely diagnosis. Comprehensive artificial intelligence (AI) that integrates multimodal imaging data, clinical notes, and large language models has the potential to support radiologists. Accordingly, the U.S. Food and Drug Administration has cleared more than 770 AI medical devices that focus on radiology, primarily based on deep learning. However, algorithm development and validation remain challenging. Limitations include sparse expert-annotated data and regulatory hurdles. Clinical implementation and the adaptation of the radiologic community is also lagging behind. Additionally, technical barriers exist regarding data availability, large language model explainability, deep learning model generalization, and clinical integration. Advances in few-shot learning, self-supervised models, and centralized platforms may support consolidated AI ecosystems. Although progress has been made, much work is still needed on data infrastructure, responsible clinical translation, and workflow integration. Continuous multidisciplinary efforts are required to optimize AI safety and truly augment radiologists' work through comprehensive solutions. By overcoming the remaining challenges, AI may strengthen health care systems through improved diagnosis. This review addresses integration challenges, pathways for responsible progress, and the viewpoints of all stakeholders.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e240982"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.242924
Sarah Eskreis-Winkler, Arka Bhowmik, Lori H Kelly, Roberto Lo Gullo, Donna D'Alessio, Kristin Belen, Molly P Hogan, Nicole B Saphier, Varadan Sevilimedu, Janice S Sung, Christopher E Comstock, Elizabeth J Sutton, Katja Pinker
RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.243833
Frederikus A Klok, Stefano Barco, Laurent Bertoletti, Sanjeev Bhalla, Suzanne Dubois, Grégorie Le Gal, L B Haramati, Erica van Hooidonk, Marc Humbert, Stavros V Konstantinides, Irene M Lang, William S Murphy, Yoshiharu Ohno, Susanna Price, Mathias Prokop, Piotr Pruszczyk, Alexia Rossi, Patricia A Thistlethwaite, Carol West, Martine Remy-Jardin
RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.243263
Shehbaz Ansari, Brian H Mu, John Findley, Sudeep H Bhabad, Miral D Jhaveri
{"title":"Case 342.","authors":"Shehbaz Ansari, Brian H Mu, John Findley, Sudeep H Bhabad, Miral D Jhaveri","doi":"10.1148/radiol.243263","DOIUrl":"10.1148/radiol.243263","url":null,"abstract":"<p><strong>History: </strong>A 70-year-old woman presented with progressively worsening midback pain over 2 months, radiating in a wraparound distribution to the lower ribs. Initially, the pain was confined to the night but eventually began to persist during the day, worsening with sitting and lying down. The pain was severe and unresponsive to paracetamol and nonsteroidal anti-inflammatory drugs. She reported no bowel or bladder issues and no weakness, numbness, or history of trauma. There was no radiculopathy in either lower extremity. She had no fever, weight loss, or history of using blood thinners. She was a former smoker with a prior transbronchial biopsy for a pulmonary nodule that was negative for malignancy or infection. She had a sister diagnosed with ovarian cancer. Physical examination demonstrated normal vital signs; preserved orientation to person, place, and time; and intact short-term and long-term memory. She had normal gait and coordination. Muscle strength was rated five of five for all four extremities, with intact sensation. Deep tendon reflexes were rated two or higher throughout. No clonus was present, and Hoffmann sign was negative. A lumbar puncture was performed at the bedside. Cerebrospinal fluid (CSF) analysis (Table) revealed an increased protein level (379 mg/dL [3790 mg/L]; reference range: 7-35 mg/dL [70-350 mg/L]) and a mildly decreased glucose level (41 mg/dL [2.3 mmol/L]; reference range, 45-70 mg/dL [2.5-3.9 mmol/L]). There was an elevated CSF lymphocyte count (94 cells/µL; reference range, 0-10 cells/µL). CSF cytologic examination and flow cytometry revealed small lymphoid cells without immunophenotypic abnormalities, suggesting an absence of clonal proliferation. Two oligoclonal bands were present in the CSF (absent in the concurrent serum sample), which was below the threshold for oligoclonal band positivity (four bands). CSF culture, DNA tests for cytomegalovirus and Epstein-Barr virus, polymerase chain reaction tests for herpes simplex virus 1 and 2 and varicella-zoster virus, and autoimmune encephalopathy panels were negative. Both serum and CSF angiotensin-converting enzyme levels were within normal limits. At initial presentation, imaging of the spine and spinal canal included unenhanced CT of the thoracic spine (Fig 1) and contrast-enhanced MRI of the thoracic spine (Fig 2). Contrast-enhanced MRI of the brain was also performed (not shown), which was unremarkable aside from chronic microvascular ischemic changes. Specifically, no dural thickening or intracranial enhancing lesion was identified. Contrast-enhanced CT of the chest, abdomen, and pelvis (not shown) was unremarkable, showing no pulmonary nodules, features of primary malignancy, or lymphadenopathy. Incidental findings included emphysema, likely related to the patient's smoking history. The patient subsequently underwent T6 laminectomy followed by treatment with glucocorticoids and rituximab. Follow-up thoracic spine MRI (Fig 3) was performed ","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e243263"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.250903
Fredrik Strand
{"title":"AI-directed Adaptive Breast MRI: A Paradigm Shift in Screening Protocols.","authors":"Fredrik Strand","doi":"10.1148/radiol.250903","DOIUrl":"https://doi.org/10.1148/radiol.250903","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e250903"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.242634
Wendie A Berg, Adrienne Vargo, Amy H Lu, Jeremy M Berg, Andriy I Bandos, Jamie Y Hartman, Margarita L Zuley, Marie A Ganott, Amy E Kelly, Bronwyn E Nair, Denise M Chough, Ruthane F Reginella, Luisa P Wallace, Kimberly S Harnist, Beatrice A Carlin, Cathy S Cohen, Christiane M Hakim, Jules H Sumkin
RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.251568
David J Murphy, Sean Quinn
{"title":"Shift to the Right: Cardiac MRI-Derived Right Ventricular Strain May Be Prognostic in Heart Failure with Preserved Ejection Fraction.","authors":"David J Murphy, Sean Quinn","doi":"10.1148/radiol.251568","DOIUrl":"https://doi.org/10.1148/radiol.251568","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e251568"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.240085
Mark L Schiebler, Masahiro Jinzaki, Masahiro Yanagawa, Amir Pourmorteza, Yoshitake Yamada, Yoko Kato, Noriaki Wada, Cornelia Schaefer-Prokop, Vincent Dousset, Noriyuki Tomiyama, Mathias Prokop, João A Lima, Hiroto Hatabu
{"title":"Future Applications of Cardiothoracic CT.","authors":"Mark L Schiebler, Masahiro Jinzaki, Masahiro Yanagawa, Amir Pourmorteza, Yoshitake Yamada, Yoko Kato, Noriaki Wada, Cornelia Schaefer-Prokop, Vincent Dousset, Noriyuki Tomiyama, Mathias Prokop, João A Lima, Hiroto Hatabu","doi":"10.1148/radiol.240085","DOIUrl":"10.1148/radiol.240085","url":null,"abstract":"<p><p>Radiologists are witnessing astonishing innovation and advancement of CT technologies and their clinical applications. This review highlights how photon-counting CT (PCCT), upright CT, and artificial intelligence (AI) may impact cardiothoracic CT applications for imaging and diagnosis. PCCT relies on new detectors that can bin the separate photon energies and allow for lower radiation dose and better spatial resolution. The clinical applications of PCCT in the coronary arteries are becoming the new standard for cardiac CT imaging. New upright CT has shown the benefits of imaging in the upright position and offers new insight into how the upright position affects biomechanics and physiology. Four-dimensional CT, which can be used to directly image perfusion, is challenging MRI and MR angiography for primacy in this area. The burgeoning role of AI and informatics is changing the way radiologists interpret and report many imaging examinations. The future is bright and promises lower radiation and intravenous contrast agent doses and higher spatial resolution, and will further incorporate deep learning to improve the effectiveness of CT.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e240085"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-06-01DOI: 10.1148/radiol.250964
Maya Honda, Mami Iima
{"title":"Preoperative Diffusion-weighted Imaging to Reduce the Burden on Patients with Breast Cancer.","authors":"Maya Honda, Mami Iima","doi":"10.1148/radiol.250964","DOIUrl":"https://doi.org/10.1148/radiol.250964","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e250964"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}