RadiologyPub Date : 2025-03-01DOI: 10.1148/radiol.233459
Martina Pecoraro, Stefano Cipollari, Emanuele Messina, Ludovica Laschena, Ailin Dehghanpour, Antonella Borrelli, Francesco Del Giudice, Valdair Francisco Muglia, Hebert Alberto Vargas, Valeria Panebianco
{"title":"Multiparametric MRI for Bladder Cancer: A Practical Approach to the Clinical Application of VI-RADS.","authors":"Martina Pecoraro, Stefano Cipollari, Emanuele Messina, Ludovica Laschena, Ailin Dehghanpour, Antonella Borrelli, Francesco Del Giudice, Valdair Francisco Muglia, Hebert Alberto Vargas, Valeria Panebianco","doi":"10.1148/radiol.233459","DOIUrl":"https://doi.org/10.1148/radiol.233459","url":null,"abstract":"<p><p>Multiparametric MRI of the bladder is highly accurate in the detection and local staging of bladder cancer. The Vesical Imaging Reporting and Data System (VI-RADS) scoring system has improved the diagnostic accuracy, reproducibility, and interpretability of bladder MRI in the assessment of the invasion of the muscularis propria. There are several technical details concerning bladder MRI that need to be strictly applied to obtain the highest possible diagnostic potential from the MRI. In addition, image evaluation, accurate interpretation, and reporting need to be standardized to optimize diagnostic accuracy and interreader agreement. This review describes the patient population for bladder MRI and discusses, with a practical approach, the correct acquisition protocol for optimal image quality using VI-RADS with reporting tips, pitfalls, and challenges for its clinical application. This review also discusses the latest evidence, clinical implications, current controversies, and future challenges, including gaps in knowledge, of the VI-RADS scoring system.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 3","pages":"e233459"},"PeriodicalIF":12.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-03-01DOI: 10.1148/radiol.250387
Ashkan A Malayeri, Baris Turkbey
{"title":"Unveiling the Future: A Deep Learning Model for Accurate Detection of Adrenal Nodules.","authors":"Ashkan A Malayeri, Baris Turkbey","doi":"10.1148/radiol.250387","DOIUrl":"https://doi.org/10.1148/radiol.250387","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 3","pages":"e250387"},"PeriodicalIF":12.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-03-01DOI: 10.1148/radiol.250135
Amy M Fowler
{"title":"<sup>18</sup>F-Fluoroestradiol PET/CT for Staging Low-Grade Estrogen Receptor-Positive Breast Cancer.","authors":"Amy M Fowler","doi":"10.1148/radiol.250135","DOIUrl":"https://doi.org/10.1148/radiol.250135","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 3","pages":"e250135"},"PeriodicalIF":12.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-03-01DOI: 10.1148/radiol.242775
Swati Deshmukh
{"title":"Peripheral Nerve Imaging: MR Neurography versus High-Resolution US.","authors":"Swati Deshmukh","doi":"10.1148/radiol.242775","DOIUrl":"https://doi.org/10.1148/radiol.242775","url":null,"abstract":"<p><p>\u0000 <i>\"Just Accepted\" papers have undergone full peer review and have been accepted for publication in <i>Radiology</i>. This article will undergo copyediting, layout, and proof review before it is published in its final version. Please note that during production of the final copyedited article, errors may be discovered which could affect the content.</i>\u0000 </p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 3","pages":"e242775"},"PeriodicalIF":12.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-03-01DOI: 10.1148/radiol.241850
Jelijn J Knip, Ramsha Iqbal, Emma C Bonjer, Lemonitsa H Mammatas, Annette A van Zweeden, Paola Perin, Jaap J M Teunissen, Gwen M P Diepenhorst, Laura J Schijf, Sandra D Bakker, Noortje Schoenmakers, Susanne van der Velde, Ellis Barbé, Katya Duvivier, Inge R Konings, Gerben J C Zwezerijnen, Albert D Windhorst, Ronald Boellaard, Daniela E Oprea-Lager, C Willemien Menke-van der Houven van Oordt
{"title":"The Diagnostic Accuracy of <sup>18</sup>F-FDG PET and <sup>18</sup>F-FES PET for Staging Grade 1-2 Estrogen Receptor-Positive Breast Cancer.","authors":"Jelijn J Knip, Ramsha Iqbal, Emma C Bonjer, Lemonitsa H Mammatas, Annette A van Zweeden, Paola Perin, Jaap J M Teunissen, Gwen M P Diepenhorst, Laura J Schijf, Sandra D Bakker, Noortje Schoenmakers, Susanne van der Velde, Ellis Barbé, Katya Duvivier, Inge R Konings, Gerben J C Zwezerijnen, Albert D Windhorst, Ronald Boellaard, Daniela E Oprea-Lager, C Willemien Menke-van der Houven van Oordt","doi":"10.1148/radiol.241850","DOIUrl":"https://doi.org/10.1148/radiol.241850","url":null,"abstract":"<p><p>Background According to current guidelines, staging of patients with locally advanced breast cancer and local-regional recurrent breast cancer is preferably performed with PET using 2-fluorine 18-fluoro-2-deoxy-d-glucose (<sup>18</sup>F-FDG). However, <sup>18</sup>F-FDG PET might underperform in low-grade estrogen receptor (ER)-positive breast cancer. Alternatively, 16α-<sup>18</sup>F-fluoro-17β-estradiol (<sup>18</sup>F-FES) has emerged as a powerful tracer for in vivo visualization of ER-positive lesions. Purpose To assess whether <sup>18</sup>F-FES PET improves staging of grade 1 or 2 ER-positive breast cancer compared with <sup>18</sup>F-FDG PET. Materials and Methods Patients with clinical stage II/III or local-regional recurrent, grade 1 or 2, ER-positive breast cancer were included between December 2018 and January 2021 in this prospective multicenter pilot study. All participants underwent an <sup>18</sup>F-FES PET examination in addition to standard staging with conventional imaging and <sup>18</sup>F-FDG PET. Both PET scans were independently assessed. The disease stage was determined independently based on conventional imaging and <sup>18</sup>F-FDG PET or <sup>18</sup>F-FES PET. Relevant lesions suspected of malignancy were verified histopathologically, after which a final stage was determined. Results A total of 41 female participants (median age, 56 years [IQR, 48-71 years]) with 44 breast tumors were included. Overall, 29 of 41 participants (71%) were correctly staged at <sup>18</sup>F-FDG PET compared with 34 of 41 (83%) at <sup>18</sup>F-FES PET (<i>P</i> = .18). Seven of 10 and nine of 10 cases of lobular breast cancer were correctly staged at <sup>18</sup>F-FDG and <sup>18</sup>F-FES PET, respectively (70% vs 90%; <i>P</i> = .38) and seven of 12 and 11 of 12 cases of grade 1 tumors, respectively (58% vs 92%; <i>P</i> = .06). Regional lymph nodes were incorrectly staged at <sup>18</sup>F-FDG PET in six of 44 cases (14%), whereas all cases were correctly staged at <sup>18</sup>F-FES PET (<i>P</i> = .02). Both imaging methods had a sensitivity of 100% (95% CI: 59, 100) and a specificity of 91% (95% CI: 76, 98) for the detection of metastatic disease. Conclusion In this prospective pilot study, there was no evidence of a difference in diagnostic accuracy of <sup>18</sup>F-FES PET and <sup>18</sup>F-FDG PET in staging patients with grade 1 or 2 ER-positive breast cancer. Clinical trial registration no. NCT03726931 Published under a CC BY 4.0 license <i>Supplemental material is available for this article.</i> See also the editorial by Fowler in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 3","pages":"e241850"},"PeriodicalIF":12.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-03-01DOI: 10.1148/radiol.240966
Adarsh Ghosh, Eric Crotty
{"title":"Alternating Views on the ABR Alternate Pathway.","authors":"Adarsh Ghosh, Eric Crotty","doi":"10.1148/radiol.240966","DOIUrl":"https://doi.org/10.1148/radiol.240966","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 3","pages":"e240966"},"PeriodicalIF":12.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-03-01DOI: 10.1148/radiol.243270
Ali S Tejani, Bardia Khosravi, Cody H Savage, Linda Moy, Charles E Kahn, Paul H Yi
{"title":"AI-generated Podcast Summaries of <i>Radiology</i> Articles: Analysis of Content and Quality.","authors":"Ali S Tejani, Bardia Khosravi, Cody H Savage, Linda Moy, Charles E Kahn, Paul H Yi","doi":"10.1148/radiol.243270","DOIUrl":"https://doi.org/10.1148/radiol.243270","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"314 3","pages":"e243270"},"PeriodicalIF":12.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologyPub Date : 2025-03-01DOI: 10.1148/radiol.241479
Milán Vecsey-Nagy, Giuseppe Tremamunno, U Joseph Schoepf, Chiara Gnasso, Emese Zsarnóczay, Nicola Fink, Dmitrij Kravchenko, Moritz C Halfmann, Jim O'Doherty, Bálint Szilveszter, Pál Maurovich-Horvat, Ismail Mikdat Kabakus, Pal Spruill Suranyi, Tilman Emrich, Akos Varga-Szemes