Radiology最新文献

{"title":"Perfusion beyond Margin in Hepatocellular Carcinoma: A Contrast-enhanced US Feature Related to Tumor Invasiveness and Prognosis","authors":"Wenzhen Ding,Ran Ji,Chuan Pang,Jianming Li,Fangyi Liu,Jie Yu,Ping Liang","doi":"10.1148/radiol.260918","DOIUrl":"https://doi.org/10.1148/radiol.260918","url":null,"abstract":"Perfusion beyond margin is a new imaging feature that was effectively identified through contrast-enhanced US of patients with hepatocellular carcinoma and was associated with greater invasive potential and poorer prognosis.","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"36 1","pages":""},"PeriodicalIF":19.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MOLLI versus ShMOLLI at 3-T Cardiac MRI: Normal Values in Healthy Individuals and Common Cardiac Conditions.","authors":"Jean-Nicolas Dacher, Farah Cadour","doi":"10.1148/radiol.262292","DOIUrl":"https://doi.org/10.1148/radiol.262292","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"321 1","pages":"e262292"},"PeriodicalIF":17.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocardial T1 Mapping at 3 T: A Comparison of MOLLI and ShMOLLI across Healthy Volunteers and Various Cardiovascular Pathologies.","authors":"Huaying Zhang, Chen Cui, Wenli Zhou, Tingting Zheng, Wenjing Yang, Di Zhou, Yining Wang, Leyi Zhu, Mengdi Jiang, Xinqiao Lian, Vanessa M Ferreira, Shihua Zhao, Qiang Zhang, Stefan K Piechnik, Minjie Lu","doi":"10.1148/radiol.252886","DOIUrl":"https://doi.org/10.1148/radiol.252886","url":null,"abstract":"<p><p>Background The clinical utility of quantitative T1 mapping in cardiac MRI is constrained by variability across acquisition protocols, and a comprehensive comparison between commonly used sequences remains unavailable. Purpose To provide a full range of cardiac MRI native T1 and extracellular volume fraction (ECV) values at 3 T in healthy Chinese adults and participants with various cardiovascular diseases and, as a secondary aim, to establish the relationship between modified Look-Locker inversion recovery (MOLLI) and shortened MOLLI (ShMOLLI) measurements. Materials and Methods This prospective study included healthy volunteers, participants with normal cardiac MRI findings, and participants representing 13 cardiovascular conditions. All participants underwent 3-T cardiac MRI with both MOLLI and ShMOLLI sequences during a single examination. Global native T1 and ECV values were quantified and compared between sequences and across disease groups. Statistical approaches included <i>t</i> tests, Pearson correlation, Bland-Altman analysis, and Cohen D standardization. Results This study included 1237 clinical participants (mean age ± SD: 51 years ± 14.8; 854 men). Reference values (adjusted mean ± SE) in healthy volunteers were 1170 msec ± 9 (MOLLI) and 1135 msec ± 10 (ShMOLLI) for native T1 and were 24.8% ± 0.6 (both MOLLI and ShMOLLI) for ECV, with women showing higher native T1 values than men (all <i>P</i> ≤ .002). MOLLI yielded systematically higher native T1 than ShMOLLI across all conditions (mean difference: 46.0 msec ± 27.2; all <i>P</i> < .01), whereas ECV did not differ for most conditions (10 of 15 groups; <i>P</i> > .05). Strong intersequence correlations were observed for native T1 (Pearson <i>r</i> = 0.93; <i>P</i> < .001) and ECV (<i>r</i> = 0.95; <i>P</i> < .001). After standardization to sequence-specific baselines, pathologic deviations were comparable between sequences (Cohen D differences ≤0.5 in most groups). A supplementary swine study supported the technical validity of both sequences (<i>r</i> = 0.87-0.90; <i>P</i> < .001). Conclusion In participants who underwent 3-T cardiac MRI with both MOLLI and ShMOLLI sequences, native T1 was higher with MOLLI than ShMOLLI, but ECV was consistent across sequences. © RSNA, 2026 <i>Supplemental material is available for this article.</i> See also the editorial by Dacher and Cadour in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"321 1","pages":"e252886"},"PeriodicalIF":17.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardizing Liver MR Elastography: Guidelines for Reliable Stiffness Measurement in Chronic Liver Disease","authors":"Suraj D. Serai,Kay Pepin,Jun Chen,Sudhakar K. Venkatesh,Nancy A. Obuchowski,Patricia E. Cole,Richard L. Ehman,for the QMIC MRE Biomarker Committee","doi":"10.1148/radiol.260974","DOIUrl":"https://doi.org/10.1148/radiol.260974","url":null,"abstract":"Standardized MR elastography enables reliable liver stiffness measurement, with a change of at least 19% reflecting a true biological difference with 95% confidence, supporting longitudinal assessment of chronic liver disease.","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"1 1","pages":""},"PeriodicalIF":19.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Fibrosis: Clinical Importance of Vascular Assessment at Noncontrast CT in Interstitial Lung Disease","authors":"Tae Iwasawa","doi":"10.1148/radiol.262643","DOIUrl":"https://doi.org/10.1148/radiol.262643","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"11 1","pages":""},"PeriodicalIF":19.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Magnetic Resonance derived Myocardial Strain: Applications, Acquisition Techniques, Analysis, and Reporting. A Scientific Statement of the Society for Cardiovascular Magnetic Resonance, Radiological Society of North America, and European Association of Cardiovascular Imaging of the ESC.","authors":"Gaurav S Gulsin, Bharath Ambale-Venkatesh, Leon Axel, David A Bluemke, Gabriella Captur, João L Cavalcante, Daniel B Ennis, Frederick H Epstein, Bernhard Gerber, Kate Hanneman, Nadine Kawel-Boehm, Sebastian Kelle, Christopher M Kramer, João A C Lima, Hildo J Lamb, Minjie Lu, Thomas H Marwick, Simone Romano, Alistair A Young, Gerry P McCann","doi":"10.1148/radiol.261385","DOIUrl":"10.1148/radiol.261385","url":null,"abstract":"<p><p>Myocardial strain imaging enables quantification of cardiac deformation. Cardiovascular magnetic resonance imaging (CMR) is well suited for strain assessment due to the ability to image in any given plane with high spatial and contrast resolution. CMR strain measures have incremental diagnostic and prognostic utility over conventional clinical imaging parameters across disease states. Routine integration of CMR strain assessment in clinical practice has been hindered by the lack of agreement on imaging protocols and analysis methods, variability due to noise sensitivity, and a paucity of robust normative age-, sex- and ethnicity-specific reference ranges. In recognition of the expanding applications of strain techniques in clinical and research CMR, this joint SCMR/RSNA/EACVI scientific statement integrates data from original research studies, guidelines, and opinions from experts across the field to guide responsible and evidence-based utilization of CMR strain. © 2026 The Author(s). Published by Elsevier Inc. on behalf of Society for Cardiovascular Magnetic Resonance, by Oxford University Press on behalf of European Society of Cardiology, and by RSNA. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by/4.0/). <i>Supplemental material is available for this article.</i> This paper was jointly developed by <i>Journal of Cardiovascular Magnetic Resonance, European Heart Journal - Cardiovascular Imaging</i>, and <i>Radiology</i> and jointly published by Elsevier Inc, Oxford University Press, and RSNA. The articles are identical except for minor stylistic and spelling differences in keeping with each journal's style. Any citation can be used when citing this article.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"321 1","pages":"e261385"},"PeriodicalIF":17.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplemental Breast Cancer Screening with Contrast-enhanced Mammography or Abbreviated MRI for Extremely Dense Breasts: The DENSE-2 Trial.","authors":"Sophie E L van Grinsven, Evelyn M Monninkhof, Ritse M Mann, Marc B I Lobbes, Mireille J M Broeders, Nicolien T van Ravesteyn, Adriana M J Bluekens, Paul J van Diest, Monique D Dorrius, Katya M Duvivier, Maaike P M Gielens, Mathijn D F de Jong, Marc C J M Kock, Claudette E Loo, Carla Meeuwis, Cécile de Monyé, Thiemo J A van Nijnatten, Ruud M Pijnappel, Johanna P Trap-de Jong, Jeroen Veltman, Wouter B Veldhuis, Carla H van Gils","doi":"10.1148/radiol.260333","DOIUrl":"10.1148/radiol.260333","url":null,"abstract":"<p><p>Women with extremely dense breasts have an increased risk of breast cancer but also a decreased sensitivity of mammography. The Dense Tissue and Early Breast Neoplasm Screening (DENSE) trial, initiated in 2011, showed that supplemental full-protocol MRI screening reduced the number of interval cancers in women with extremely dense breasts. Cost-effective screening scenarios have been described, but imaging costs and capacity remain barriers to implementing full-protocol MRI in population-based breast cancer screening programs. Therefore, the DENSE-2 trial was set up to investigate two alternate screening techniques, contrast-enhanced mammography (CEM) or abbreviated MRI (AB-MRI), that are expected to be cheaper and to make more efficient use of the available capacity while potentially achieving similar results to full-protocol MRI. DENSE-2 is a multicenter randomized controlled trial embedded in the Dutch screening program. It comprises two consecutive screening rounds in which women receive the same breast imaging technique both times. The trial investigates the value of supplemental screening with CEM or AB-MRI in women with extremely dense breasts with a negative screening mammogram. The primary aim is to determine whether these methods will lead to a reduction of interval cancers compared with mammography. The DENSE-2 trial results will provide insights into the performance, feasibility, and acceptability of both screening modalities, enable long-term outcome modeling, and support decision-making on the most appropriate screening strategy for women with extremely dense breasts. ClinicalTrials.gov: NCT06636370 © RSNA, 2026 <i>Supplemental material is available for this article.</i> See also the editorial by Bahl in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"321 1","pages":"e260333"},"PeriodicalIF":17.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Cohort Harmonization of Quantitative MRI Metrics: Considerations for Reference Value Generalizability","authors":"Jin-Yi Xiang,Jing-Ping Wu,Lian-Ming Wu","doi":"10.1148/radiol.261397","DOIUrl":"https://doi.org/10.1148/radiol.261397","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"32 1","pages":""},"PeriodicalIF":19.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149088774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normal Pressure Hydrocephalus as a Gradual Spectrum of Anomaly.","authors":"Sven Haller","doi":"10.1148/radiol.262645","DOIUrl":"https://doi.org/10.1148/radiol.262645","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"321 1","pages":"e262645"},"PeriodicalIF":17.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Next Step in Supplemental Screening for Extremely Dense Breasts.","authors":"Manisha Bahl","doi":"10.1148/radiol.262635","DOIUrl":"https://doi.org/10.1148/radiol.262635","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"321 1","pages":"e262635"},"PeriodicalIF":17.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}