Radiology最新文献

{"title":"Diagnostic Performance of CT/MRI LI-RADS Version 2018 Major Feature Combinations: Individual Participant Data Meta-Analysis.","authors":"Robert G Adamo, Christian B van der Pol, Mostafa Alabousi, Eric Lam, Jean-Paul Salameh, Nicole Abedrabbo, Emily Lerner, Haresh Naringrekar, Mustafa R Bashir, Andreu F Costa, Hoda Osman, Danyaal Ansari, Brooke Levis, Adam Polikoff, Alessandro Furlan, An Tang, Andrea S Kierans, Amit G Singal, Ashwini Arvind, Ayman Alhasan, Brian C Allen, Caecilia S Reiner, Christopher Clarke, Daniel R Ludwig, Federico Diaz Telli, Federico Piñero, Grzegorz Rosiak, Hanyu Jiang, Heejin Kwon, Hong Wei, Hyo-Jin Kang, Ijin Joo, Jeong Ah Hwang, Ji Hye Min, Ji Soo Song, Jin Wang, Joanna Podgórska, John R Eisenbrey, Krzysztof Bartnik, Li-Da Chen, Marco Dioguardi Burgio, Maxime Ronot, Milena Cerny, Nieun Seo, Sheng-Xiang Rao, Roberto Cannella, Sang Hyun Choi, Tyler J Fraum, Wentao Wang, Woo Kyoung Jeong, Xiang Jing, Yeun-Yoon Kim, Matthew D F McInnes","doi":"10.1148/radiol.243450","DOIUrl":"10.1148/radiol.243450","url":null,"abstract":"<p><p>Background The CT/MRI Liver Imaging Reporting and Data System (LI-RADS) diagnostic algorithm classifies liver observations in patients with high-risk hepatocellular carcinoma (HCC) using imaging features. However, data regarding the diagnostic performance of specific LI-RADS major feature combinations is limited. Purpose To conduct a systematic review and individual participant data (IPD) meta-analysis to establish the positive predictive values (PPVs) of LI-RADS major feature combinations using CT/MRI LI-RADS version 2018 in patients at risk for HCC. Materials and Methods Medline, Embase, Cochrane Central, and Scopus were searched for studies published from January 2014 to February 2023. Studies reporting HCC percentages for LI-RADS categories in patients at high risk for HCC were included. A one-stage random-effects IPD meta-analysis was used to calculate the PPV for HCC diagnosis and 95% CIs of major feature combinations. Wald test was used to compare combinations. Risk of bias (RoB) was assessed using Quality Assessment of Diagnostic Accuracy Studies 2, known as QUADAS-2 (protocol: <i>https://osf.io/ah5kn</i>). Results Forty-six studies including 6765 patients (mean age, 59 years ± 10.69 [SD]; 75% male patients [5081 of 6765]; age range, 18-93 years) with 7500 liver observations were analyzed. High RoB in at least one domain was found in 80% of studies (37 of 46). The pooled PPV estimate for major feature combinations was 58.28% in LR-3 (95% CI: 44.00, 71.29), 80.82% in LR-4 (95% CI: 71.04, 87.86), and 95.81% in LR-5 (95% CI: 91.06, 98.09). The majority of LI-RADS major feature combinations had PPVs that did not differ from others within the same category, supporting the current categorization (<i>P</i> value ranges: LR-3, .17-.73; LR-4, .10 to >.99; LR-5, .08 to >.99). Notably, five major feature combinations differed from the pooled PPV of the LR category. LR-3 was lower without nonrim arterial phase hyperenhancement (APHE) measuring smaller than 20 mm without additional major features (14.81%; 95% CI: 6.35, 30.85; <i>P</i> < .001), and higher with APHE measuring 10-19 mm without additional major features (68.33%; 95% CI: 53.94, 79.90; <i>P</i> = .01). LR-4 was lower without APHE measuring 20 mm or larger with enhancing capsule (50.81%; 95% CI: 28.92, 72.39; <i>P</i> = .009). LR-5 was lower with APHE measuring 10-19 mm with threshold growth (74.40%; 95% CI: 51.06, 89.00; <i>P</i> < .001), and with APHE measuring 20 mm or larger with threshold growth (82.35%; 95% CI: 57.29, 94.20; <i>P</i> = .02). Conclusion This meta-analysis showed that most major feature combinations in the same CT/MRI LI-RADS category had similar PPVs for HCC in patients at high risk for HCC, with the exception of five combinations within LR-3 through LR-5. © RSNA, 2025 <i>Supplemental material is available for this article.</i> See also the editorial by Johnson in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e243450"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Vision-Language Models for Detection and Deidentification of Medical Images with Burned-In Protected Health Information.","authors":"Taehee Lee, Hyungjin Kim, Seong Ho Park, Seonhye Chae, Soon Ho Yoon","doi":"10.1148/radiol.243664","DOIUrl":"10.1148/radiol.243664","url":null,"abstract":"<p><p>Background Advances in vision-language models (VLMs) may enable detection and deidentification of burned-in protected health information (PHI) on medical images. Purpose To investigate the ability of commercial and open-source VLMs to detect burned-in PHI on medical images, confirm full deidentification, and obscure PHI where present. Materials and Methods In this retrospective study, records of deceased patients aged 18 years or older who died during admission at a tertiary hospital between January and June 2021 were randomly selected. One study per modality was randomly selected. Images were preprocessed to ensure burned-in PHI and test four scenarios of deidentification conditions: all PHI text is visible, PHI text is redacted using asterisks, PHI text is removed, and all text is removed. Real PHI was replaced with fictitious data to protect privacy. Four VLMs (three commercial: ChatGPT-4o [OpenAI], Gemini 1.5 Pro [Google]), and Claude-3 Haiku [Anthropic]; one open-source: Llama 3.2 Vision 11B [Meta]) were tested on three tasks: task 1, overall confirmation of deidentification; task 2, detection and specification of any identifiable PHI items; and task 3, detection and specification of the five preselected PHI items (name, identification number, date of birth, age, and sex). Text was extracted from images using an open-source Tesseract optical character recognition software and input into the VLMs for the same tasks. Additionally, the capability of each VLM to mask detected PHI fields was evaluated. Statistical comparisons were conducted using χ², independent <i>t</i> tests, or generalized estimating equations. Results Data from 100 deceased patients (mean age, 71.1 years ± 10.1 [SD]; 57 male) with 709 imaging studies were randomly included. Among 6696 PHI occurrences, ChatGPT-4o achieved deidentification verification accuracy of 95.0% (<i>n</i> = 6362) for task 1, 61.2% (<i>n</i> = 4098) for task 2, and 96.2% (<i>n</i> = 6441) for task 3, outperforming Gemini 1.5 Pro (68.1%, 55.2%, and 86.3% for tasks 1-3, respectively), Claude-3 Haiku (75.8%, 86.9%, and 79.4% for tasks 1-3, respectively), and Llama 3.2 Vision 11B (51.6%, 66.9%, and 74.3% for tasks 1-3, respectively) (<i>P</i> < .001 for all). Direct image analysis by ChatGPT-4o and Gemini 1.5 Pro was more accurate than the optical character recognition software for PHI detection across all three deidentification verification tasks (<i>P</i> < .001 for all). Among 375 PHI occurrences on 100 images, ChatGPT-4o successfully obscured 81.1% (<i>n</i> = 304) of them. Conclusion ChatGPT-4o demonstrated substantial potential in detecting, verifying, and obscuring burned-in PHI on medical images. © RSNA, 2025 <i>Supplemental material is available for this article.</i> See also the editorial by Pinto dos Santos in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e243664"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How I Do It: Imaging Evaluation of Neonatal Bowel Obstructions.","authors":"Nathan C Hull, Abdusamea Shabani, Pedro Daltro, Kushaljit Singh Sodhi, Charles Maxfield, Edward Y Lee","doi":"10.1148/radiol.241778","DOIUrl":"https://doi.org/10.1148/radiol.241778","url":null,"abstract":"<p><p>Neonatal bowel obstruction is one of the most common surgical emergencies in neonates in daily clinical practice. Because most causes of bowel obstruction in neonates are different from those in older children and adults, a clear understanding of the specific causes and how to properly evaluate them is important for optimal care. Imaging evaluation plays an essential role in initial workup, accurate diagnosis, and proper guidance of subsequent management in these patients. This up-to-date article provides radiologists with a practical imaging approach and techniques for evaluating neonatal bowel obstruction. The spectrum of underlying causes of neonatal upper and lower bowel obstruction is discussed using a pattern-based approach to analyze characteristic imaging findings. The preferred diagnostic imaging modalities and key imaging features to distinguish these causes of obstructions from other differential diagnoses are highlighted.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e241778"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteitis Fibrosa Cystica of the Skull Caused by Vitamin D Deficiency.","authors":"Jing Ren, Qingyu Ji","doi":"10.1148/radiol.241923","DOIUrl":"https://doi.org/10.1148/radiol.241923","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e241923"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reinventing the Wheel: Patient's History Is Half of the Diagnosis.","authors":"Andrea Laghi","doi":"10.1148/radiol.243496","DOIUrl":"https://doi.org/10.1148/radiol.243496","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e243496"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case 338: Right Retroperitoneal Lymphatic-Venous Malformation.","authors":"Amar Shah, Maria Zulfiqar","doi":"10.1148/radiol.242728","DOIUrl":"10.1148/radiol.242728","url":null,"abstract":"<p><strong>History: </strong>A 25-year-old female patient presented to the emergency department with worsening abdominal discomfort over the past 2-3 months. The patient had not experienced fever, chills, or dysuria. Past medical history was notable for two completed pregnancies; otherwise, there was no pertinent medical history or family history. At physical examination, the patient was uncomfortable but not in acute distress. There was tenderness to palpation in the right upper quadrant and epigastric region, but no rebound tenderness or guarding. Vital signs were blood pressure of 141/85 mm Hg, pulse rate of 91/min, and temperature of 37.2 °C. The serum β-human chorionic gonadotropin test result was negative for pregnancy, and urinalysis showed no leukocyte esterase or nitrites. Routine blood investigations, including white blood cell count, were within normal limits. Initial evaluation with contrast-enhanced CT of the abdomen and pelvis was performed, followed by MRI of the abdomen without and with intravenous contrast material.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e242728"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right Ventricular Strain Improves Cardiac MRI-based Prognostication in Heart Failure with Preserved Ejection Fraction.","authors":"Leyi Zhu, Huaying Zhang, Mengdi Jiang, Jing Xu, Di Zhou, Weichun Wu, Wenjing Yang, Yining Wang, Gang Yin, Arlene Sirajuddin, Andrew E Arai, Qiang Zhang, Shihua Zhao, Minjie Lu","doi":"10.1148/radiol.243080","DOIUrl":"10.1148/radiol.243080","url":null,"abstract":"<p><p>Background Right ventricular (RV) function is an independent predictor of clinical status and prognosis in multiple cardiovascular diseases; however, the prognostic value of RV strain in patients with heart failure with preserved ejection fraction (HFpEF) remains largely unknown. Purpose To determine the associations between RV strain variables derived from cardiac MRI feature tracking and adverse outcomes in patients with HFpEF. Materials and Methods This retrospective study included patients with HFpEF who underwent cardiac MRI from January 2010 to December 2018. The primary end point was all-cause mortality. The results were validated in a cohort of patients with HFpEF enrolled from January 2019 to June 2021. Cox regression analysis was performed to assess the associations between variables and clinical outcomes. Results The development cohort comprised 1019 patients (mean age, 56.9 years ± 12.3 [SD]; 710 men), and the validation cohort comprised 273 patients (mean age, 55.3 years ± 14.0; 191 men). During a median follow-up of 7.8 and 3.9 years, respectively, 103 patients in the development cohort and nine in the validation cohort died. Multivariable Cox regression analysis showed that RV global longitudinal and circumferential strain were independent predictors of all-cause mortality (adjusted hazard ratio per 1% increase, 1.07 [95% CI: 1.02, 1.12; <i>P</i> = .005] and 1.13 [95% CI: 1.05, 1.21; <i>P</i> < .001], respectively). The full model based on clinical, conventional imaging, and RV strain variables demonstrated the best discrimination performance in the development (C index = 0.794) and validation (C index = 0.782) cohorts. In a subgroup with T1 mapping data, RV global longitudinal and circumferential strain remained independent predictors after separate adjustment for native T1 value and extracellular volume fraction (all models, <i>P</i> < .05). Conclusion RV global longitudinal and circumferential strain derived from cardiac MRI were independent predictors of adverse outcomes in patients with HFpEF, providing greater prognostic value than traditional clinical and imaging-derived risk markers. © RSNA, 2025 <i>Supplemental material is available for this article.</i> See also the editorial by Murphy and Quinn in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e243080"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on Liquid Biopsy.","authors":"Marius E Mayerhoefer, Andreas Kienzle, Sungmin Woo, Hebert Alberto Vargas","doi":"10.1148/radiol.241030","DOIUrl":"10.1148/radiol.241030","url":null,"abstract":"<p><p>Liquid biopsy helps detect cells and cell-derived metabolites, proteins, nucleic acids, and vesicles that are shed into body fluids by tumors. This diagnostic test requires only approximately 10 mL of blood or urine. It has received considerable attention as a minimally invasive tool for whole-body tumor interrogation for use in patients with cancer. It poses an attractive and potentially cost-effective alternative to invasive tissue sampling through tissue biopsies, especially serial assessments, such as for treatment response evaluation and mutations that occur during cancer treatment. Cell-free and circulating tumor DNA are the most frequently tested liquid biopsy analytes, and have shown promise for cancer screening, assessment of residual disease after treatment, and clinical outcome prediction and prognostication. Whereas liquid biopsy is less sensitive than imaging in early tumor stages, it is more specific and may help detect treatment response earlier than the Response Evaluation Criteria in Solid Tumors, or RECIST. Aimed primarily at radiologists, this review article provides an update on recent developments in the use of liquid biopsy, including findings from landmark clinical trials and U.S. regulatory approvals as companion diagnostic tests for clinical use, particularly in four malignancies: lymphoma, breast cancer, prostate cancer, and melanoma. Finally, current challenges for the clinical implementation of liquid biopsy are discussed.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e241030"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum for: Preoperative Diagnosis of Ipsilateral and Contralateral Breast Cancer: Role of Diffusion-weighted MRI.","authors":"Ha Jung Kim, Savannah C Partridge, JungBok Lee, Heera Yoen, Woo Kyung Moon, Su Min Ha","doi":"10.1148/radiol.259012","DOIUrl":"10.1148/radiol.259012","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e259012"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulation of Cortical and Hippocampal Functional MRI Connectivity Following Transcranial Alternating Current Stimulation in Mild Alzheimer Disease.","authors":"Tao Wang, Shaozhen Yan, Yi Shan, Hanxiao Xue, Yi Xing, Sheng Bi, Zhigeng Chen, Hanyu Xi, Zhigang Qi, Yi Tang, Jie Lu","doi":"10.1148/radiol.241463","DOIUrl":"10.1148/radiol.241463","url":null,"abstract":"<p><p>Background Transcranial alternating current stimulation (tACS) may be effective for improving cognitive function in Alzheimer disease (AD), but its impact on brain functional connectivity (FC) has not been well studied. Purpose To evaluate tACS efficacy in improving cognitive performance and modulating FC between brain regions in individuals with AD using functional MRI. Materials and Methods In this prospective randomized controlled trial (September 2020 to April 2022), participants with mild AD were assigned to active (40 Hz tACS with 15-mA intensity) or sham (no γ frequency or current) tACS groups for 3 weeks (referred to as week 3), with a 3-month follow-up (referred to as month 3). Functional MRI and cognitive testing were performed at baseline, week 3, and month 3. Primary outcomes were changes in Mini-Mental State Examination and Montreal Cognitive Assessment scores from baseline to week 3. Secondary outcomes included FC changes within multiple cortical networks and between cortex and hippocampus from baseline to week 3 and month 3, assessed using Fisher <i>z</i>-transformed correlation coefficient (hereafter, <i>z</i> score). Results Forty-six participants were randomized into the active group (<i>n</i> = 23; median age, 66 years; IQR, 62-69 years; 16 female participants) or the sham group (<i>n</i> = 23; mean age, 64 years; IQR, 61-69 years; 14 female participants). The active group had higher Mini-Mental State Examination (median score change, 2 [IQR, 1-5] vs 0 [IQR, -1 to 2]; <i>P</i> = .001) and Montreal Cognitive Assessment (median score change, 2 [IQR, 0-4] vs 0 [IQR, -1 to 2]; <i>P</i> = .03) scores than the sham group at week 3, respectively. Compared with the sham group, the active group had increased FC between left hippocampus and left middle cingulate gyrus (<i>z</i> score difference, 0.29; 95% CI: 0.17, 0.42; false discovery rate [FDR]-adjusted <i>P</i> < .001) and between the left hippocampus and the left middle frontal gyrus (<i>z</i> score difference, 0.16; 95% CI: 0.03, 0.29; FDR-adjusted <i>P</i> = .04) within the posterior default-mode network (<i>z</i> score difference, 0.40; 95% CI: 0.07, 0.73; FDR-adjusted <i>P</i> = .046) and within the visual network (<i>z</i> score difference, 0.45; 95% CI: 0.17, 0.73; FDR-adjusted <i>P</i> = .007) from baseline to week 3. Conclusion Cognitive performance in mild AD improved following tACS, with increased FC within cortical networks and between the hippocampus and specific cortical regions. ClinicalTrials.gov Identifier: NCT03920826 © RSNA, 2025 <i>Supplemental material is available for this article.</i> See also the editorial by Shepherd in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"315 3","pages":"e241463"},"PeriodicalIF":12.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}