Kristin D.F. Negley , Gina M. Foster , Robin Beaupre , Kelly Breck , Amanda Schulz , Marissa Ruechel , Desiree Neumann
{"title":"152 Improving the Anticoagulation Program Enrollment Process: A Collaboration between Unlicensed Assistive Personnel and Registered Nurses to Improve Practice and Patient Care","authors":"Kristin D.F. Negley , Gina M. Foster , Robin Beaupre , Kelly Breck , Amanda Schulz , Marissa Ruechel , Desiree Neumann","doi":"10.1016/j.rpth.2025.102807","DOIUrl":"10.1016/j.rpth.2025.102807","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102807"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neonatal intracardiac thrombosis secondary to transplacental transfer of maternal antiphospholipid antibodies-a case report and review of the literature","authors":"Katherine Girgulis , Leslie Skeith , Deborah Fruitman , Megan Barber , Nancy Soliman , Nicole Johnson , Macgregor Steele","doi":"10.1016/j.rpth.2025.102895","DOIUrl":"10.1016/j.rpth.2025.102895","url":null,"abstract":"<div><h3>Background</h3><div>Maternal antiphospholipid immunoglobulin (Ig) G antibodies can cross the placenta, placing neonates at uncertain risk for thrombosis. There are no previous reports of neonatal intracardiac thrombosis (ICT) in the context of anticardiolipin antibodies (aCL).</div></div><div><h3>Key Clinical Question</h3><div>What were the clinical manifestations, management, and outcomes for a mother and her child with ICT secondary to presumed transplacental transfer of aCL?</div></div><div><h3>Clinical Approach</h3><div>A 2-week-old female presented with reduced feeding and was found to be poorly perfused with significant lactic acidosis. A mobile mass was noted near the left atrial appendage on the echocardiogram and confirmed on cardiac magnetic resonance imaging. Magnetic resonance imaging of the brain was normal, with no evidence of stroke. The aCL IgG titers returned highly positive for the infant (115.3 IgG phospholipid (GPL)-Unit [U]/mL) and mother (>160 GPL-U/mL; >99th percentile local reference is ≥20 GPL-U/mL). There were no other overt risk factors for thrombosis. The infant received 6 months of enoxaparin until aCL normalized. There remains a small calcified thrombus adherent to the left atrial wall. At 2 years old, the child remains healthy with no cardiac, neurologic, nor thrombotic sequelae.</div></div><div><h3>Conclusion</h3><div>This is the first report of neonatal ICT presumed secondary to maternal aCL. The outcome was favorable with anticoagulation management. Further research is needed in the area of transplacental antiphospholipid antibody transfer, identification of neonates at risk, and optimal clinical management.</div></div>","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 4","pages":"Article 102895"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144231670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yiheng Zhang , Owen J.T. McCarty , Joseph E. Aslan
{"title":"ZO-2 seals the deal for platelet tight junctions","authors":"Yiheng Zhang , Owen J.T. McCarty , Joseph E. Aslan","doi":"10.1016/j.rpth.2025.102952","DOIUrl":"10.1016/j.rpth.2025.102952","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 4","pages":"Article 102952"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacob C. Cogan , Allison E. Burnett , Alexandra Power-Hays , Geoffrey D. Barnes , Ming Y. Lim
{"title":"Identifying and addressing underuse in hematologic care through systems-based hematology","authors":"Jacob C. Cogan , Allison E. Burnett , Alexandra Power-Hays , Geoffrey D. Barnes , Ming Y. Lim","doi":"10.1016/j.rpth.2025.102881","DOIUrl":"10.1016/j.rpth.2025.102881","url":null,"abstract":"<div><div>Underuse of high-value hematologic care receives comparatively less attention than the overuse of unnecessary tests and treatments. In this review, we analyze examples of underutilized care in several domains: procedural (inferior vena cava filter retrieval), medical (hydroxyurea use in sickle cell anemia), and patient-facing (education prior to anticoagulation). For each, we justify the need for increased uptake and highlight examples of systems-based hematology interventions to accomplish this. While reducing overused care is appealing from a cost savings perspective, we advocate for equal attention and investment toward promoting underused care.</div></div>","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 4","pages":"Article 102881"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Osama Abdelsamad , Dania Alkhiyami , Syed Yameen Hasan , Eman Alhmoud , Rasha Al Anany
{"title":"80 Thrombophilia Screening in Inpatients: A Review of Testing Appropriateness and Clinical Impact in a Tertiary Hospital in Qatar","authors":"Osama Abdelsamad , Dania Alkhiyami , Syed Yameen Hasan , Eman Alhmoud , Rasha Al Anany","doi":"10.1016/j.rpth.2025.102801","DOIUrl":"10.1016/j.rpth.2025.102801","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102801"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144202961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S.H. Bakhru , X. Jiang , L. Chen , D. Osmani , A. Balaj , K. Kronen , D. Mootoo , F. LaDuca , J. Ansell
{"title":"158 Clinical Performance of a Novel Point-of-Care Coagulometer, the Perosphere ClotChek™, for the DOACS","authors":"S.H. Bakhru , X. Jiang , L. Chen , D. Osmani , A. Balaj , K. Kronen , D. Mootoo , F. LaDuca , J. Ansell","doi":"10.1016/j.rpth.2025.102786","DOIUrl":"10.1016/j.rpth.2025.102786","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102786"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laurie A. Sardo , Julia A. Bayadinova , Emma K. Sardo
{"title":"190 Patient Compliance with Aspirin and Rivaroxaban Post Elective Joint Replacement Surgery: A Quality Assurance Initiative","authors":"Laurie A. Sardo , Julia A. Bayadinova , Emma K. Sardo","doi":"10.1016/j.rpth.2025.102811","DOIUrl":"10.1016/j.rpth.2025.102811","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102811"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ibtihal Mahmoud Abdallah , Asma Eltahir , Rana Moustafa Al-Adawi , Mohamed Abdelgelil , Abdul Moqeeth Mohammed , Asmaa Mohamed
{"title":"144 Anticoagulation in Patients with Provoked Venous Thromboembolism: A Real-World Analysis of Clinical Characteristics, Management Strategies, and Outcomes from an Outpatient Tertiary Anticoagulation Clinic in Qatar","authors":"Ibtihal Mahmoud Abdallah , Asma Eltahir , Rana Moustafa Al-Adawi , Mohamed Abdelgelil , Abdul Moqeeth Mohammed , Asmaa Mohamed","doi":"10.1016/j.rpth.2025.102827","DOIUrl":"10.1016/j.rpth.2025.102827","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102827"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alyssa R. George , Katelyn W. Sylvester , Dareen M. Kanaan , Prabashni Reddy , Jean M. Connors , Nathan T. Connell
{"title":"135 Real World Experience with Use of Coagulation Factor VIIa (Recombinant)-jncw (SevenFact®) at an Academic Medical Center","authors":"Alyssa R. George , Katelyn W. Sylvester , Dareen M. Kanaan , Prabashni Reddy , Jean M. Connors , Nathan T. Connell","doi":"10.1016/j.rpth.2025.102753","DOIUrl":"10.1016/j.rpth.2025.102753","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102753"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Kluck , Jennifer Hardman , Lisa Baumann Kreuziger , Hannah Breidenbach , Eric Mendez-Michler , Michelle Te Ronde , Jesse Kutz , Rebecca Wong
{"title":"170 Creation of Patient Self-Managed Warfarin Program Within an Anticoagulation Clinic","authors":"Julia Kluck , Jennifer Hardman , Lisa Baumann Kreuziger , Hannah Breidenbach , Eric Mendez-Michler , Michelle Te Ronde , Jesse Kutz , Rebecca Wong","doi":"10.1016/j.rpth.2025.102825","DOIUrl":"10.1016/j.rpth.2025.102825","url":null,"abstract":"","PeriodicalId":20893,"journal":{"name":"Research and Practice in Thrombosis and Haemostasis","volume":"9 ","pages":"Article 102825"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}