Recent Research in Science and Technology最新文献

Exploring diverse aspects of celiac disease - A review 探索乳糜泻的不同方面--综述

Recent Research in Science and Technology Pub Date : 2024-07-01 DOI: 10.25081/rrst.2024.16.8885

Akanksha Chandrakar

{"title":"Exploring diverse aspects of celiac disease - A review","authors":"Akanksha Chandrakar","doi":"10.25081/rrst.2024.16.8885","DOIUrl":"https://doi.org/10.25081/rrst.2024.16.8885","url":null,"abstract":"Celiac disease is a chronic inflammatory disorder triggered by the ingestion of gluten-containing foods in genetically susceptible individuals. This multifactorial disease has both genetic and environmental components, with gluten serving as the environmental trigger and specific genetic variations in the major histocompatibility complex region contributing to the genetic predisposition. Contrary to previous assumptions, celiac disease is not a rare disorder, with a global prevalence estimated at approximately 1%. However, it often remains under-recognized because many affected individuals do not exhibit the classic gastrointestinal symptoms associated with the condition. Instead, they may present with nonspecific manifestations of nutritional deficiencies or may be entirely asymptomatic. Celiac disease is associated with an increased incidence of autoimmune disorders, and its identification in asymptomatic or silent cases is crucial for managing associated conditions and preventing long-term complications such as lymphoma. The relationship between celiac disease and other autoimmune disorders, particularly type 1 diabetes, suggests a potential trigger role for gluten. In this article we review the development of celiac disease, including its types, pathogenesis, clinical features, and associated diseases or complications. We will also discuss available tests, treatments, and preventive approaches related to this subject.","PeriodicalId":20870,"journal":{"name":"Recent Research in Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141694938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulation of cell proliferation and tumor suppressor roles of microRNA 329-3p of the MAP kinase pathway in cervical squamous carcinoma 宫颈鳞状细胞癌中 MAP 激酶通路的 microRNA 329-3p 对细胞增殖的调控作用和肿瘤抑制作用

Recent Research in Science and Technology Pub Date : 2024-06-04 DOI: 10.25081/rrst.2024.16.8922

Elfansu, Faria Rashid, K. Abirami, Sivakumar Krishnamoorthy, Kshitija Aherkar, R. Mythreyi, Uthamalingam Murali, Kanthesh M. Basalingappa, S. Jagannathan, E. Boojhana, M. Maghimaa

{"title":"Regulation of cell proliferation and tumor suppressor roles of microRNA 329-3p of the MAP kinase pathway in cervical squamous carcinoma","authors":"Elfansu, Faria Rashid, K. Abirami, Sivakumar Krishnamoorthy, Kshitija Aherkar, R. Mythreyi, Uthamalingam Murali, Kanthesh M. Basalingappa, S. Jagannathan, E. Boojhana, M. Maghimaa","doi":"10.25081/rrst.2024.16.8922","DOIUrl":"https://doi.org/10.25081/rrst.2024.16.8922","url":null,"abstract":"Cervical squamous cell carcinoma is observed as the second major cause of mortality worldwide. A highly conserved mitogen-activated protein kinase (MAPK) signaling pathway occurs in a wide range of cellular processes which includes differentiation, proliferation, migration, senescence, and apoptosis. MAPK pathway can be activated by various extracellular signals, capable of generating responses as per the cell type. Thus, alteration of the EGFR receptor in this particular pathway leads to the condition of cancer due to abnormal activation of receptor tyrosine kinases. The characteristic features of microRNA (miRNA) which are endogenous, single-stranded, small non-coding RNA for their role in RNA silencing and post-transitional regulation of gene expression have been studied over the years. The miRNA functions by base pairing with the complementary sequences within the mRNA molecule. One such miRNA, miR-329-3p has a critical tumor suppressor role in the MAPK pathway, however, is least understood. Therefore, miRNA could be considered as a potential biomarker for diagnosis, prognosis, and therapeutic purposes and brought out to its fullest use to mankind.","PeriodicalId":20870,"journal":{"name":"Recent Research in Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141387826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights into ancient ceramic technology: a comprehensive analysis of mineralogy, chemistry and firing conditions 透视古代陶瓷技术：矿物学、化学和烧制条件的综合分析

Recent Research in Science and Technology Pub Date : 2024-02-08 DOI: 10.25081/rrst.2024.16.8758

S. Mammadov, A. Ahadova

{"title":"Insights into ancient ceramic technology: a comprehensive analysis of mineralogy, chemistry and firing conditions","authors":"S. Mammadov, A. Ahadova","doi":"10.25081/rrst.2024.16.8758","DOIUrl":"https://doi.org/10.25081/rrst.2024.16.8758","url":null,"abstract":"The intensive integration of Azerbaijan into the global economy, mainly through international gas and oil pipeline construction, has led to significant archaeological research in the past two decades. The construction of the Baku-Tbilisi-Ceyhan oil pipeline (BTC) and the Southern Caucasus Pipeline gas pipeline (SCP) prompted a four-year archaeological fieldwork program, followed by a six-year post-excavation program. The current work applied an interdisciplinary approach using various instrumental methods for studying ancient artifacts found during those projects. The thermogravimetric method and differential thermal analysis were employed to obtain insights into the production technology of the ancient pottery and information about the mineralogy of the ceramic sherds. The complex processes involved in firing the ceramic paste have been studied extensively, and patterns in mass loss ratios during different temperature ranges have been established. In total, 15 samples were investigated, and the thermogravimetric analysis of ceramic shards revealed that the firing temperature of the samples was in the range of 700 °C. XRD analysis confirmed the presence of quartz, feldspar, and clay minerals in the ceramic samples. The presence of calcite and other specific minerals is subject to the origin of the ceramic materials. The results obtained from this multidisciplinary approach provide insights into the firing technology and the origin of the ceramic samples.","PeriodicalId":20870,"journal":{"name":"Recent Research in Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139853765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights into ancient ceramic technology: a comprehensive analysis of mineralogy, chemistry and firing conditions 透视古代陶瓷技术：矿物学、化学和烧制条件的综合分析

Recent Research in Science and Technology Pub Date : 2024-02-08 DOI: 10.25081/rrst.2024.16.8758

S. Mammadov, A. Ahadova

{"title":"Insights into ancient ceramic technology: a comprehensive analysis of mineralogy, chemistry and firing conditions","authors":"S. Mammadov, A. Ahadova","doi":"10.25081/rrst.2024.16.8758","DOIUrl":"https://doi.org/10.25081/rrst.2024.16.8758","url":null,"abstract":"The intensive integration of Azerbaijan into the global economy, mainly through international gas and oil pipeline construction, has led to significant archaeological research in the past two decades. The construction of the Baku-Tbilisi-Ceyhan oil pipeline (BTC) and the Southern Caucasus Pipeline gas pipeline (SCP) prompted a four-year archaeological fieldwork program, followed by a six-year post-excavation program. The current work applied an interdisciplinary approach using various instrumental methods for studying ancient artifacts found during those projects. The thermogravimetric method and differential thermal analysis were employed to obtain insights into the production technology of the ancient pottery and information about the mineralogy of the ceramic sherds. The complex processes involved in firing the ceramic paste have been studied extensively, and patterns in mass loss ratios during different temperature ranges have been established. In total, 15 samples were investigated, and the thermogravimetric analysis of ceramic shards revealed that the firing temperature of the samples was in the range of 700 °C. XRD analysis confirmed the presence of quartz, feldspar, and clay minerals in the ceramic samples. The presence of calcite and other specific minerals is subject to the origin of the ceramic materials. The results obtained from this multidisciplinary approach provide insights into the firing technology and the origin of the ceramic samples.","PeriodicalId":20870,"journal":{"name":"Recent Research in Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139793539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tribological property evaluation, optimization and performance of waste sunflower oil based green cutting fluid with silicon dioxide nanoparticles as additive 以二氧化硅纳米颗粒为添加剂的废葵花籽油基绿色切削液摩擦学性能评价、优化及性能研究

Recent Research in Science and Technology Pub Date : 2023-11-07 DOI: 10.25081/rrst.2023.15.8433

N. Ajmal, T. Maneesh, S. Rani, Visakh Mohanan, Ananthan D. Thampi

引用次数: 0

Convertible staircase lift 可转换楼梯升降机

Recent Research in Science and Technology Pub Date : 2023-11-07 DOI: 10.25081/rrst.2023.15.8436

G. V. M. Abhiram, M. Balaji, R. Naveen, M. Sai Kiran, Md. A. H. Irshad, T. Bharat

{"title":"Convertible staircase lift","authors":"G. V. M. Abhiram, M. Balaji, R. Naveen, M. Sai Kiran, Md. A. H. Irshad, T. Bharat","doi":"10.25081/rrst.2023.15.8436","DOIUrl":"https://doi.org/10.25081/rrst.2023.15.8436","url":null,"abstract":"The present work investigates the design and analysis of a staircase lift, which can be used as a Material Handling System. A staircase lift is a mechanical device for lifting people and wheelchairs up and down the stairs, who may find difficulty in doing so themselves. For sufficiently wide stairs, a rail is mounted to the treads of the stairs. A chair or lifting platform is attached to the rail. A person on the chair or platform is lifted as the chair or platform moves along the rail, old age and goods are to be carried across the staircase. A staircase lift is a type of lift that can be mounted on the staircase without altering civil structure. Not only altering, but the person need not change the seat from the wheelchair to the staircase lift, there is a foldable supporting rod for the staircase lift which directly attaches to the wheelchair. This lift runs on electric power and consists of a motor, reduction gearbox, rope drive, two rails and a sliding chair. In this system, we use a DC motor for changing the polarity of the power supply which will make the motor run in reverse direction. Advantages over the conventional hydraulic lift are no civil structure and alteration is required, low cost, less bulkiness, less power, less maintenance required. Easy design, easy installations can be of industrial use too. Moreover, considering some drawbacks due to weight carrying capacity completely depends upon the capacity of the motor. There is a lot of scope for further modification in the project as using a monorail instead of two, using a belt drive or chain drive instead of a rope drive. Incorporation and automation/timer unit will ease the use of the device. Rack and carrier arrangement for using the device for a curved staircase and use of work & roller reduction gear assembly.","PeriodicalId":20870,"journal":{"name":"Recent Research in Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135540558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and prototyping of an innovative design for automatic paper bag making machine 一种创新设计的自动制袋机的开发和原型制作

Recent Research in Science and Technology Pub Date : 2023-11-07 DOI: 10.25081/rrst.2023.15.8460

P. Nithul, V. K. Vikas

引用次数: 0

Static and dynamic wireless charging system for electric vehicle 电动汽车静态和动态无线充电系统

Recent Research in Science and Technology Pub Date : 2023-11-07 DOI: 10.25081/rrst.2023.15.8435

Antony Jithin, Akshath Sasi, Chris Jaison, A. J. Bensen, A. R. Reghuraj

{"title":"Static and dynamic wireless charging system for electric vehicle","authors":"Antony Jithin, Akshath Sasi, Chris Jaison, A. J. Bensen, A. R. Reghuraj","doi":"10.25081/rrst.2023.15.8435","DOIUrl":"https://doi.org/10.25081/rrst.2023.15.8435","url":null,"abstract":"Electrified transportation will help to reduce greenhouse gas emissions and petrol prices. Electrified transportation demands that a wide variety of charging networks be set up, in a user-friendly environment, to encourage adoption. Wireless electric vehicle charging systems (WEVCS) can be a potential alternative technology to charge electric vehicles (EVs) without any plug-in problems. This paper outlines the currently available wireless power transfer technology for EVs. In addition, it also includes wireless transformer structures with a variety of ferrite shapes, which have been researched. WEVCS are associated with health and safety issues, which have been discussed with the current development in international standards. Two major applications, static and dynamic WEVCS, are explained, and up-to-date progress with features from research laboratories, universities, and industries is recorded. Moreover, future upcoming concepts-based WEVCS, such as ‘‘vehicle-to-grid (V2G)” and ‘‘in-wheel” wireless charging systems (WCS) are reviewed and examined, with qualitative comparisons with other existing technology.","PeriodicalId":20870,"journal":{"name":"Recent Research in Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135540557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility study on formulation of cutting fluid from waste palm oil 废棕榈油制备切削液的可行性研究

Recent Research in Science and Technology Pub Date : 2023-11-07 DOI: 10.25081/rrst.2023.15.8438

Shabna Yoosuf, T. Maneesh, Baiju Sasidharan, S. Rani, N. Ajmal, Visakh Mohanan

引用次数: 0

Comprehensive review of key parameters for improving the performance of Solar Air Heaters 提高太阳能空气加热器性能的关键参数综述

Recent Research in Science and Technology Pub Date : 2023-09-08 DOI: 10.25081/rrst.2023.15.8570

Raj Kumar, Kedar Narayan Bairwa

引用次数: 0