Radiologia Brasileira最新文献_第9页

Estimativas de riscos com radiações ionizantes 电离辐射风险估计

Radiologia Brasileira Pub Date : 2023-06-01 DOI: 10.1590/0100-3984.2023.56.3e5

Renato Dimenstein

引用次数: 0

Câncer de mama após radioterapia torácica em pacientes jovens: o que o radiologista precisa saber? 年轻患者胸部放射治疗后的乳腺癌:放射科医生需要知道什么?

Radiologia Brasileira Pub Date : 2023-06-01 DOI: 10.1590/0100-3984.2022.0065

Bianca Miranda Lago, Stella dos Santos Bello, Guilherme Rocha Melo Gondim, Fabiana Baroni Alves Makdissi, A. Bitencourt

引用次数: 0

O papel do corregistro automático de imagens e da dosimetria interna na medicina personalizada 图像自动联合记录和内部剂量测定在定制药物中的作用

Radiologia Brasileira Pub Date : 2023-06-01 DOI: 10.1590/0100-3984.2023.56.3e4

Leonardo Alexandre-Santos, L. Wichert-Ana

引用次数: 0

Aspectos tomográficos da histoplasmose pulmonar: ensaio iconográfico

Radiologia Brasileira Pub Date : 2023-06-01 DOI: 10.1590/0100-3984.2022.0106

Ana Luiza Di Mango, A. C. Gomes, Bruno Hochhegger, Gláucia Zanetti, Edson Marchiori

引用次数: 0

Behavior of total alkaline phosphatase after radium-233 therapy in metastatic castration-resistant prostate cancer: a single-center, real-world retrospective study. 转移性去势抵抗性前列腺癌症镭-233治疗后总碱性磷酸酶的行为：一项单中心、真实世界的回顾性研究。

Radiologia Brasileira Pub Date : 2023-05-01 DOI: 10.1590/0100-3984.2022.0080

Flávia Paiva Proença Lobo Lopes, Marcos Villela Pedras, Álida Rosária Silva Ferreira, Patricia Massucheto Ledesma, Paulo Roberto Telles Pires Dias, Felipe Villela Pedras

{"title":"Behavior of total alkaline phosphatase after radium-233 therapy in metastatic castration-resistant prostate cancer: a single-center, real-world retrospective study.","authors":"Flávia Paiva Proença Lobo Lopes, Marcos Villela Pedras, Álida Rosária Silva Ferreira, Patricia Massucheto Ledesma, Paulo Roberto Telles Pires Dias, Felipe Villela Pedras","doi":"10.1590/0100-3984.2022.0080","DOIUrl":"10.1590/0100-3984.2022.0080","url":null,"abstract":"Objective: To describe the behavior of total alkaline phosphatase (tALP) in patients with metastatic castration-resistant prostate cancer receiving radium-223 therapy, in a real-world scenario, and to describe overall survival (OS) among such patients.Materials and methods: This was a retrospective study involving 97 patients treated between February 2017 and September 2020. Patients were stratified by the baseline tALP (normal/elevated). A tALP response was defined as a ≥ 30% reduction from baseline at week 12. For patients with elevated baseline tALP, we also evaluated treatment response as a ≥ 10% reduction in tALP after the first cycle of treatment. We defined OS as the time from the first treatment cycle to the date of death.Results: There was a significant reduction in the median tALP after each cycle of treatment (p < 0.05 for all). Data for tALP at week 12 were available for 71 of the 97 patients. Of those 71 patients, 26 (36.6%) responded. Elevated baseline tALP was observed in 47 patients, of whom 19 (40.4%) showed a response. Longer OS was observed in the patients with normal baseline tALP, in those with elevated baseline tALP that showed a response to treatment (≥ 10% reduction), and in those who received 5-6 cycles of therapy.Conclusion: The tALP may be used to predict which patients will benefit from treatment with a greater number of cycles of radium-223 therapy and will have longer OS.","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9969056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The 2021 World Health Organization classification of gliomas: an imaging approach. 2021年世界卫生组织对胶质瘤的分类：一种成像方法。

Radiologia Brasileira Pub Date : 2023-05-01 DOI: 10.1590/0100-3984.2022.0089-en

Renata Tarraf Fernandes, Gustavo Ramos Teixeira, Esther Cecin Mamere, Gabriela Alencar Bandeira, Augusto Elias Mamere

引用次数: 0

The role of automated image co-registration and internal dosimetry in personalized medicine. 自动图像配准和内部剂量测定在个性化医学中的作用。

Radiologia Brasileira Pub Date : 2023-05-01 DOI: 10.1590/0100-3984.2023.56.3e4-en

Leonardo Alexandre-Santos, Lauro Wichert-Ana

引用次数: 0

Breast cancer after thoracic radiotherapy in young patients: what does the radiologist need to know? 年轻患者胸部放疗后的乳腺癌:放射科医生需要知道什么?

Radiologia Brasileira Pub Date : 2023-05-01 DOI: 10.1590/0100-3984.2022.0065-en

Bianca Miranda Lago, Stella Dos Santos Bello, Guilherme Rocha Melo Gondim, Fabiana Baroni Alves Makdissi, Almir Galvão Vieira Bitencourt

引用次数: 0

Validation of automated image co-registration integrated into in-house software for voxel-based internal dosimetry on single-photon emission computed tomography images. 将自动图像配准集成到内部软件中，用于单光子发射计算机断层扫描图像上基于体素的内部剂量测定。

Radiologia Brasileira Pub Date : 2023-05-01 DOI: 10.1590/0100-3984.2022.0096

André Luiz Alberti Leitão, Uysha de Souza Fonda, Carlos Alberto Buchpiguel, José Willegaignon, Marcelo Tatit Sapienza

{"title":"Validation of automated image co-registration integrated into in-house software for voxel-based internal dosimetry on single-photon emission computed tomography images.","authors":"André Luiz Alberti Leitão, Uysha de Souza Fonda, Carlos Alberto Buchpiguel, José Willegaignon, Marcelo Tatit Sapienza","doi":"10.1590/0100-3984.2022.0096","DOIUrl":"10.1590/0100-3984.2022.0096","url":null,"abstract":"Objective: To develop an automated co-registration system and test its performance, with and without a fiducial marker, on single-photon emission computed tomography (SPECT) images.Materials and methods: Three SPECT/CT scans were acquired for each rotation of a Jaszczak phantom (to 0°, 5°, and 10° in relation to the bed axis), with and without a fiducial marker. Two rigid co-registration software packages-SPM12 and NMDose-coreg-were employed, and the percent root mean square error (%RMSE) was calculated in order to assess the quality of the co-registrations. Uniformity, contrast, and resolution were measured before and after co-registration. The NMDose-coreg software was employed to calculate the renal doses in 12 patients treated with 177Lu-DOTATATE, and we compared those with the values obtained with the Organ Level INternal Dose Assessment for EXponential Modeling (OLINDA/EXM) software.Results: The use of a fiducial marker had no significant effect on the quality of co-registration on SPECT images, as measured by %RMSE (p = 0.40). After co-registration, uniformity, contrast, and resolution did not differ between the images acquired with fiducial markers and those acquired without. Preliminary clinical application showed mean total processing times of 9 ± 3 min/patient for NMDose-coreg and 64 ± 10 min/patient for OLINDA/EXM, with a strong correlation between the two, despite the lower renal doses obtained with NMDose-coreg.Conclusion: The use of NMDose-coreg allows fast co-registration of SPECT images, with no loss of uniformity, contrast, or resolution. The use of a fiducial marker does not appear to increase the accuracy of co-registration on phantoms.","PeriodicalId":20842,"journal":{"name":"Radiologia Brasileira","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9981096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Insights into the prognostic potential of total alkaline phosphatase in metastatic castration-resistant prostate cancer treated with radium-223. 全碱性磷酸酶在用镭-223治疗转移性去势抵抗性前列腺癌症中的预后潜力。

Radiologia Brasileira Pub Date : 2023-05-01 DOI: 10.1590/0100-3984.2023.56.3e2

Gustavo Viani

引用次数: 0