Letícia Nascimento Carniatto, Almir Galvão Vieira Bitencourt, Thais Manfrinato Miola, Jéssica Agnello, Camila Machado Xavier, Walter Henriques da Costa
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引用次数: 0
摘要
目的:评估身体成分对接受手术治疗的肾细胞癌(RCC)患者的影响:评估接受手术治疗的肾细胞癌(RCC)患者术前身体成分的影响:这是一项回顾性研究,研究对象是52名接受全肾或部分肾切除术的RCC患者。采用体重指数对身体成分进行评估,并在第三腰椎水平进行计算机断层扫描分析,以测量内脏脂肪组织的面积以及骨骼肌的面积和密度:结果:营养不良、肥胖和骨骼肌量(SMG)不足与住院时间延长有关(分别为 p = 0.028、p = 0.02 和 p = 0.012)。虽然术后症状和再入院率较低,但SMG足够的患者的存活率高于SMG不够的患者(p = 0.003):结论:在接受手术治疗的 RCC 患者中,术前身体成分似乎与围手术期并发症的发生率无关,但 SMG 不足似乎与较差的总生存率有关。
Impact of preoperative body composition in patients with renal cell carcinoma submitted to surgical treatment.
Objective: To evaluate the impact of preoperative body composition in patients with renal cell carcinoma (RCC) undergoing surgical treatment.
Materials and methods: This was a retrospective study of 52 patients with RCC undergoing total or partial nephrectomy. Body composition assessment was performed using the body mass index, together with computed tomography analysis at the level of the third lumbar vertebra to measure the area of visceral adipose tissue, as well as the area and density of skeletal muscle mass.
Results: Malnutrition, obesity and inadequate skeletal muscle gauge (SMG) were associated with higher hospital length of stay (p = 0.028, p = 0.02 and p = 0.012, respectively). Although the rates of postoperative symptoms and readmissions were low, survival was better among the patients with an adequate SMG than among those with an inadequate SMG (p = 0.003).
Conclusion: Among patients with RCC undergoing surgical treatment, preoperative body composition does not seem to be associated with the rates of perioperative complications, although an inadequate SMG seems to be associated with worse overall survival.