Psychiatry Research最新文献

{"title":"Effects of cognitive behavioral therapy (CBT) on addictive symptoms in individuals with internet gaming disorders: A systematic review and meta-analysis","authors":"Chuntana Reangsing ,&nbsp;Waraphan Wongchan ,&nbsp;Pimkanabhon Trakooltorwong ,&nbsp;Jaruwan Thaibandit ,&nbsp;Sarah Oerther","doi":"10.1016/j.psychres.2025.116425","DOIUrl":"10.1016/j.psychres.2025.116425","url":null,"abstract":"<div><h3>Objective</h3><div>We examined the effects of Cognitive Behavioral Therapy (CBT) on addiction symptoms in patients with internet gaming disorders and examined the moderating effects of participant characteristics, research methodologies, and features of interventions.</div></div><div><h3>Methods</h3><div>We systematically searched nine databases through May 2024 without date restrictions using the following search terms: (cognitive behavio* therapy) AND (addict* OR dependen*) AND ((internet or gaming) AND dis*). Studies included were primary studies with evaluating CBT in patients with internet gaming disorders. Studies were included if they used a control group and were written in English. Both randomized control trials and quasi-experimental designs were included. We used a random-effects model to compute effect sizes (ESs) using Hedges’ g, forest plot, and Q and <em>I²</em> statistics as measures of heterogeneity. We also examined moderator analyses.</div></div><div><h3>Results</h3><div>We found 13 studies with 1,115 participants (19.08±3.99 years old) that met inclusion criteria for this meta-analysis. Overall, patients with internet gaming disorders in the CBT group demonstrated significantly lower addiction symptoms (g = 0.72, 95 %CI:.420, 1.011, <em>p</em>&lt;.001) compared to controls. Regarding moderators, funding, characteristics’ participants at baseline, group discussion, length of intervention and dose were moderators affecting the ES.</div></div><div><h3>Conclusion</h3><div>CBTs are moderately effective interventions to reduce addiction symptoms among patients with internet gaming disorders. Clinicians might consider encouraging CBTs as alternative treatments for patients with internet gaming disorders. CBTs with a long length and high dose of intervention for practicing are likely to have a greater effect in reducing addiction symptoms.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"348 ","pages":"Article 116425"},"PeriodicalIF":4.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143563714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Borderline personality disorder and antisocial traits in justice-involved males: Associations with aggression, violent crime, and adverse childhood experiences","authors":"Steffen Barra ,&nbsp;Daniel Fittipaldi ,&nbsp;Petra Retz-Junginger ,&nbsp;Johannes Merscher ,&nbsp;Daniel Turner ,&nbsp;Wolfgang Retz","doi":"10.1016/j.psychres.2025.116427","DOIUrl":"10.1016/j.psychres.2025.116427","url":null,"abstract":"<div><div>Borderline personality disorder (BPD) and antisocial traits are common in justice-involved samples, but research on their dynamics, precursors, and aftereffects regarding aggressive and violent behavior is scarce. In order to enlarge the current knowledge needed for effective risk assessment and reduction, the present study examined patterns of BPD and antisocial traits in a sample of 315 justice-involved males who had undergone psychological/psychiatric evaluation, focusing on their relations with adverse childhood experiences (ACEs), self-reported physical aggression, as well as officially registered previous and future violent crime. Based on a comprehensive analysis of psychiatric/psychological evaluation reports and individuals’ self-ratings, latent class analysis identified three distinct classes with (1) high probability of BPD and antisocial traits (<em>n</em> = 63), (2) high probability of antisocial traits only (<em>n</em> = 150), and (3) low probability of either (<em>n</em> = 102). Compared to the latter, both symptomatic classes were characterized by high ACE burden. Whereas the borderline-antisocial class showed associations with increased self-reported physical aggression but not with convictions for violent crimes, the antisocial class was related to both aggression ratings and registered violent offending. Moreover, elevated ACE scores indicated incremental predictability for physical aggression ratings and violent criminality over class membership. The present findings highlight the need to carefully assess personality disturbances and ACEs in justice-involved populations in order to apply the most effective intervention measures to address each individual's criminogenic needs as accurately as possible.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"348 ","pages":"Article 116427"},"PeriodicalIF":4.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143563715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal perinatal depression and the risk of disruptive behavioural disorder symptoms among offspring: A systematic review and meta-analysis","authors":"Biruk Shalmeno Tusa ,&nbsp;Rosa Alati ,&nbsp;Getinet Ayano ,&nbsp;Kim Betts ,&nbsp;Adisu Birhanu Weldesenbet ,&nbsp;Berihun Dachew","doi":"10.1016/j.psychres.2025.116428","DOIUrl":"10.1016/j.psychres.2025.116428","url":null,"abstract":"<div><div>Inconsistent findings exist regarding the association between maternal perinatal depression and the risk of Disruptive Behavioural Disorder (DBD) symptoms, including Conduct Disorder (CD) and Oppositional Defiant Disorder (ODD) symptoms in children and adolescents. This study aimed to estimate the overall risk of DBD symptoms in offspring of mothers who have experienced perinatal depression. PubMed, Medline, Embase, Scopus, CINAHL, and Psych INFO were searched. A meta-analysis was conducted using inverse variance-weighted random-effects models. The odds ratios (OR) with 95 % confidence intervals (CI) were presented as summary effect estimates. Among the 4,591 publications identified, 12 studies, comprising 51,468 mother-offspring pairs were included in the final analysis. A meta-analysis showed that maternal perinatal depression was associated with a 47 % increased risk of any DBD symptoms (OR = 1.47, 95 % CI = 1.18–1.76), a 41 % increased risk of CD symptoms (OR = 1.41, 95 % CI = 1.04–1.77), and a 53 % increased risk of ODD symptoms (OR = 1.53, 95 % CI = 1.11–1.94) in offspring. This meta-analysis highlights a significant link between maternal perinatal depression and an elevated risk of DBD symptoms in children and adolescents, underscoring the importance of timely interventions and support for at-risk children and adolescents.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"348 ","pages":"Article 116428"},"PeriodicalIF":4.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the role of insight, social support, and barriers in treatment engagement in individuals diagnosed with psychotic disorders","authors":"Madeline M. Ward,&nbsp;Sarah Hope Lincoln","doi":"10.1016/j.psychres.2025.116424","DOIUrl":"10.1016/j.psychres.2025.116424","url":null,"abstract":"<div><div>Treatment engagement for individuals with psychotic disorders is often low, and engagement is considered critical to improving outcomes and reducing chronicity of the illness. Lack of insight in psychosis has been associated with poor treatment engagement and is considered a core feature of psychotic disorders. One factor that may improve treatment engagement in psychosis, perhaps for individuals with low insight, is social support. Social support may improve treatment engagement by promoting insight or overriding the challenges of engagement related to insight, however, the relationships between insight, social support, and treatment engagement are not clear. The current study hypothesized that greater insight and social support would result in better treatment engagement, and that greater social support would enhance treatment engagement for individuals with low insight. Sixty-eight (N = 68) participants with a psychotic disorder completed clinical interview and self-report measures. A relationship between insight and treatment engagement was not found, thus, social support did not moderate a relationship between the two. Participants reported on multiple treatment barriers impacting treatment engagement. As such, the impact of barriers to treatment may require consideration before accurately measuring the above constructs.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"347 ","pages":"Article 116424"},"PeriodicalIF":4.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143551918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring cognitive symptoms in patients with unipolar and bipolar major depression: A comparative evaluation of subjective and objective performance","authors":"Gianluca Rosso ,&nbsp;Giorgia Porceddu ,&nbsp;Caterina Portaluppi ,&nbsp;Camilla Garrone ,&nbsp;Gabriele Di Salvo ,&nbsp;Giuseppe Maina","doi":"10.1016/j.psychres.2025.116422","DOIUrl":"10.1016/j.psychres.2025.116422","url":null,"abstract":"<div><h3>Aim</h3><div>This cross-sectional observational study aimed to assess objective and subjective cognitive deficits in patients with unipolar (UD) and bipolar depression (BD), focusing on their insight into actual cognitive abilities.</div></div><div><h3>Methods</h3><div>A total of 124 participants were recruited: 84 patients with a current major depressive episode (43 with UD, 41 with BD) and 40 age- and gender-matched healthy controls. Cognitive assessments were conducted using the Screen for Cognitive Impairment in Psychiatry (SCIP) for objective evaluation and the Perceived Deficits Questionnaire-Depression-5-item (PDQ-<span>d</span>-5) for subjective assessment. Comparisons were performed using χ² tests for categorical variables and ANCOVA for continuous variables (to compare the severity of cognitive complaints and impairment, while controlling for illness duration and age at onset). The Pearson correlation coefficient was used to examine the relationship between subjective and objective measures.</div></div><div><h3>Results</h3><div>In the objective assessment, 72.1 % of UD patients and 68.3 % of BD patients showed cognitive symptoms, with nearly half classified as moderate to severe. No significant differences were found between UD and BD in objective cognitive profiles. In subjective assessments, 39.5 % of UD patients and 46.3 % of BD patients scored below the median. BD patients reported worse subjective cognitive performance than UD patients, with lower total scores (11.1 ± 3.2 vs. 7.9 ± 4.4, <em>p &lt;</em> &lt; 0.001) and poorer performance in planning (2.8 ± 1.5 vs. 1.9 ± 1.4, <em>p &lt;</em> &lt; 0.001) and attention (3.4 ± 0.9 vs. 2.3 ± 1.5, <em>p &lt;</em> .001) domains.</div></div><div><h3>Conclusion</h3><div>This study confirms significant cognitive symptoms in both UD and BD patients. The discrepancy between subjective and objective cognitive performance in BD patients suggests a disconnect between perceived and cognitive abilities.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"347 ","pages":"Article 116422"},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multivariate deep phenotyping reveals behavioral correlates of non-restorative sleep in 22q11.2 deletion syndrome","authors":"Natacha Reich ,&nbsp;Andrea Imparato ,&nbsp;Jacinthe Cataldi ,&nbsp;Niveettha Thillainathan ,&nbsp;Farnaz Delavari ,&nbsp;Maude Schneider ,&nbsp;Stephan Eliez ,&nbsp;Francesca Siclari ,&nbsp;Corrado Sandini","doi":"10.1016/j.psychres.2025.116423","DOIUrl":"10.1016/j.psychres.2025.116423","url":null,"abstract":"<div><div>Converging evidence suggests that sleep disturbances can directly contribute to a transdiagnostic combination of behavior and neurocognitive difficulties characterizing most forms of psychopathology. However, it remains unclear how the growing comprehension of sleep neurophysiology should best inform sleep quality assessment in mental health patients.</div><div>To address this fundamental question, we performed deep multimodal sleep and behavioral phenotyping in 37 individuals at high genetic risk for psychopathology due to 22q11.2 Deletion Syndrome (Mean age:19±8.17, M/<em>F</em> = 22/15) and 34 Healthy Controls (Mean age:17.06±6.87, M/<em>F</em> = 12/22). We implemented a multivariate analysis pipeline informed by the current neurobiological understanding of the behavioral consequences of sleep disruption.</div><div>We detected multivariate patterns of disrupted sleep architecture consistently influenced by age and diagnosis across recordings and experimental settings. With high-density EEG polysomnography we detected atypical trajectories of Slow-Wave-Activity (SWA) reduction, influenced by age and sleep duration which, according to the Synaptic-Homeostasis-Hypothesis, could reflect combined alterations in neurodevelopmental and synaptic homeostasis mechanisms in 22q11DS. Blunted SWA reduction was linked with EEG markers of residual sleep pressure in morning-vs-evening EEG and with questionnaires estimating subjective somnolence in everyday life, potentially representing a clinically relevant signature of non-restorative sleep. Moreover, blunted SWA decline was linked to a transdiagnostic combination of behavioral difficulties, including negative psychotic symptoms, ADHD symptoms, and neurocognitive impairments in processing speed and inhibitory-control.</div><div>These findings suggest that systematic screening and management of sleep disturbances could directly improve behavioral outcomes in 22q11DS. They highlight the potential of precision/multivariate phenotyping approaches for characterizing the role of sleep disturbances in developmental psychopathology.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"347 ","pages":"Article 116423"},"PeriodicalIF":4.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143518986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Absence of nonfatal suicidal behavior preceding suicide death reveals differences in clinical risks","authors":"Hilary Coon ,&nbsp;Andrey A. Shabalin ,&nbsp;Emily DiBlasi ,&nbsp;Eric T. Monson ,&nbsp;Seonggyun Han ,&nbsp;Erin A. Kaufman ,&nbsp;Danli Chen ,&nbsp;Brent Kious ,&nbsp;Nicolette Molina ,&nbsp;Zhe Yu ,&nbsp;Michael J. Staley ,&nbsp;David K. Crockett ,&nbsp;Sarah M. Colbert ,&nbsp;Niamh Mullins ,&nbsp;Amanda V. Bakian ,&nbsp;Anna R. Docherty ,&nbsp;Brooks R. Keeshin","doi":"10.1016/j.psychres.2025.116391","DOIUrl":"10.1016/j.psychres.2025.116391","url":null,"abstract":"<div><div>Nonfatal suicidal behavior is the most robust predictor of suicide death. However, only ∼10 % of those who survive an attempt go on to die by suicide. Moreover, ∼50 % of suicide deaths occur in the absence of prior known attempts, suggesting risks other than nonfatal suicide attempt need to be identified to help prevent suicide mortality. We studied data from 4,000 population-ascertained suicide deaths and 26,191 population controls to improve understanding of suicide deaths without prior nonfatal attempts. This study included 2,253 suicide deaths and 3,375 controls with evidence of nonfatal suicidal ideation or behaviors (SUI_SI/SB and CTL_SI/SB) from diagnostic codes and natural language processing of electronic health records notes. Characteristics of these groups were compared to 1,669 suicides with no prior nonfatal SI/SB (SUI_None) and 22,816 controls with no lifetime suicidality (CTL_None). The SUI_None and CTL_None groups had fewer overall diagnoses and were older than SUI_SI/SB and CTL_SI/SB. Mental health diagnoses were far less common in both the SUI_None and CTL_None groups; mental health problems were far less associated with suicide death than with presence of SI/SB. Physical health diagnoses were conversely more often associated with risk of suicide death than with presence of SI/SB. Pending replication, results indicate highly significant clinical differences among suicide deaths with versus without prior nonfatal SI/SB, and suggest that, for a substantial number of individuals at risk for suicide mortality, history of SI/SB does not serve as an effective clinical marker of risk.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"347 ","pages":"Article 116391"},"PeriodicalIF":4.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient preference effects in a randomized comparative effectiveness study of electroconvulsive therapy and ketamine for treatment resistant depression: An ELEKT-D trial secondary analysis","authors":"Gerard Sanacora ,&nbsp;Brian S. Barnett ,&nbsp;Bo Hu ,&nbsp;Fernando S. Goes ,&nbsp;Sanjay J. Mathew ,&nbsp;James W. Murrough ,&nbsp;Irving Reti ,&nbsp;Samuel T. Wilkinson ,&nbsp;Amit Anand","doi":"10.1016/j.psychres.2025.116411","DOIUrl":"10.1016/j.psychres.2025.116411","url":null,"abstract":"<div><h3>Introduction</h3><div>Previous studies have shown patient preference can have large effects on treatment adherence and patient satisfaction. However, the direct effects of matching treatment with patient preference on efficacy and safety outcomes remain unclear. We aimed to evaluate the effects of patient preference and preference-matching on efficacy, adverse events, and adherence to electroconvulsive therapy (ECT) and intravenous (IV) ketamine treatments in a randomized clinical trial.</div></div><div><h3>Methods</h3><div>Data were collected during the Patient-Centered Outcomes Research Institute (PCORI) funded ECT vs. Ketamine in Patients with Treatment Resistant Depression (ELEKT-D) study, which randomized patients to treatment with either ECT or IV ketamine across five U.S. sites. We performed <em>post hoc</em>-analyses on 255 patients who provided responses to a patient preference survey following treatment phase completion, which allowed us to explore the relationships between treatment preference and several treatment outcome measures.</div></div><div><h3>Results</h3><div>Our analysis showed that (1) Ketamine was preferred by more trial participants than ECT; (2) Preference for ketamine was associated with higher likelihood of treatment response for all patients regardless of treatment assignment; (3) Preference-matching (patients receiving the treatment they indicated a moderate or strong preference for on the survey) was associated with greater likelihood of treatment response to ketamine but not ECT; (4) Preference-matching was associated with reduced rates of adverse events in ECT-treated patients. There was a trend for preference-matching potentially influencing treatment adherence.</div></div><div><h3>Conclusions</h3><div>Our findings suggest treatment preference-matching affects treatment effectiveness, adverse event reporting and possibly adherence. However, these associations may be contextual, modality dependent, and complex.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"347 ","pages":"Article 116411"},"PeriodicalIF":4.2,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143551920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of the etiology and neurobiology of intermittent explosive disorder","authors":"John Paliakkara ,&nbsp;Stacy Ellenberg ,&nbsp;Andrew Ursino ,&nbsp;Abigail A Smith ,&nbsp;James Evans ,&nbsp;Joseph Strayhorn ,&nbsp;Stephen V. Faraone ,&nbsp;Yanli Zhang-James","doi":"10.1016/j.psychres.2025.116410","DOIUrl":"10.1016/j.psychres.2025.116410","url":null,"abstract":"<div><div>Intermittent Explosive Disorder (IED) is characterized by repeated inability to control aggressive impulses. Although the etiology and neurobiology of impulsive anger and impulse control disorders have been reviewed, no systematic review on these aspects has been published for IED specifically. We conducted a systematic search in seven electronic databases for publications about IED, screened by two authors, and retained twenty-four studies for the review. Our findings highlight a multifactorial etiology and neurobiology of IED, emphasizing the role of the amygdala and orbitofrontal cortex in emotional regulation and impulse control, and supporting interventions that target serotonergic signaling. Research also shows that childhood trauma and adverse family environment may significantly contribute to the development of IED. Yet, genetic studies focusing on IED were largely lacking, despite many examining the genetics underlying aggression as a general trait or other related disorders. Future research using consistently defined IED as a phenotype is required to better understand the etiology and underlying mechanisms and assist in informing the development of more effective interventions for IED.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"347 ","pages":"Article 116410"},"PeriodicalIF":4.2,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical, cognitive, creativity and cultural measures in dissociative identity disorder: A controlled study","authors":"Aikaterini Ι. Strouza ,&nbsp;Eline M. Vissia ,&nbsp;Yolanda R. Schlumpf ,&nbsp;Eugenie del Marmol ,&nbsp;Ellert R.S. Nijenhuis ,&nbsp;Nel Draijer ,&nbsp;D.J. Veltman ,&nbsp;Antje A.T.S. Reinders","doi":"10.1016/j.psychres.2025.116407","DOIUrl":"10.1016/j.psychres.2025.116407","url":null,"abstract":"<div><h3>Background</h3><div>Dissociative identity disorder (DID) is associated with severe clinical and cognitive debilitating psychopathology. Additionally, it is often thought that creativity and cultural differences contribute to DID's symptomatology. Thus, the present study aimed to expand previous empirical data by investigating differences in clinical, cognitive, creativity and cultural measures between two distinct samples in order to gain a better insight into this disorder.</div></div><div><h3>Methods</h3><div>Clinical, cognitive and creativity self-reported measures of 97 participants from The Netherlands and Switzerland were compared between two groups: 32 participants with DID and a control group of 65 controls.</div></div><div><h3>Results</h3><div>Participants with DID scored significantly higher than the control group on the majority of clinical and creativity scales, but not on the cognitive measures.</div></div><div><h3>Conclusion</h3><div>Outcomes indicate heightened dissociative, depressive and anxiety symptomatology, as well as increased traumatic experiences, parental affectionate control and sleep disturbances in individuals with DID as compared to controls. These findings replicate and corroborate previous empirical findings and support the Trauma Model of DID. No cultural differences were observed between Dutch and Swiss individuals with DID.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"348 ","pages":"Article 116407"},"PeriodicalIF":4.2,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}