Maternal perinatal depression and the risk of disruptive behavioural disorder symptoms among offspring: A systematic review and meta-analysis

IF 4.2 2区医学 Q1 PSYCHIATRY

Psychiatry Research Pub Date : 2025-03-04 DOI:10.1016/j.psychres.2025.116428

Biruk Shalmeno Tusa , Rosa Alati , Getinet Ayano , Kim Betts , Adisu Birhanu Weldesenbet , Berihun Dachew

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引用次数: 0

Abstract

Inconsistent findings exist regarding the association between maternal perinatal depression and the risk of Disruptive Behavioural Disorder (DBD) symptoms, including Conduct Disorder (CD) and Oppositional Defiant Disorder (ODD) symptoms in children and adolescents. This study aimed to estimate the overall risk of DBD symptoms in offspring of mothers who have experienced perinatal depression. PubMed, Medline, Embase, Scopus, CINAHL, and Psych INFO were searched. A meta-analysis was conducted using inverse variance-weighted random-effects models. The odds ratios (OR) with 95 % confidence intervals (CI) were presented as summary effect estimates. Among the 4,591 publications identified, 12 studies, comprising 51,468 mother-offspring pairs were included in the final analysis. A meta-analysis showed that maternal perinatal depression was associated with a 47 % increased risk of any DBD symptoms (OR = 1.47, 95 % CI = 1.18–1.76), a 41 % increased risk of CD symptoms (OR = 1.41, 95 % CI = 1.04–1.77), and a 53 % increased risk of ODD symptoms (OR = 1.53, 95 % CI = 1.11–1.94) in offspring. This meta-analysis highlights a significant link between maternal perinatal depression and an elevated risk of DBD symptoms in children and adolescents, underscoring the importance of timely interventions and support for at-risk children and adolescents.

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来源期刊

Psychiatry Research 医学-精神病学

CiteScore

17.40

自引率

1.80%

发文量

527

审稿时长

57 days

期刊介绍： Psychiatry Research offers swift publication of comprehensive research reports and reviews within the field of psychiatry. The scope of the journal encompasses: Biochemical, physiological, neuroanatomic, genetic, neurocognitive, and psychosocial determinants of psychiatric disorders. Diagnostic assessments of psychiatric disorders. Evaluations that pursue hypotheses about the cause or causes of psychiatric diseases. Evaluations of pharmacologic and non-pharmacologic psychiatric treatments. Basic neuroscience studies related to animal or neurochemical models for psychiatric disorders. Methodological advances, such as instrumentation, clinical scales, and assays directly applicable to psychiatric research.