Psychiatry Research最新文献_第2页

Dissociative episodes and concurrent heart rate in patients with PTSD - An ecological momentary assessment. 创伤后应激障碍患者的分离性发作和并发心率--生态瞬间评估。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2025-01-02 DOI: 10.1016/j.psychres.2024.116345

Sarah Beutler-Traktovenko, Marcel Franz, Judith Daniels, Julia Schellong, Kerstin Weidner, Ilona Croy

{"title":"Dissociative episodes and concurrent heart rate in patients with PTSD - An ecological momentary assessment.","authors":"Sarah Beutler-Traktovenko, Marcel Franz, Judith Daniels, Julia Schellong, Kerstin Weidner, Ilona Croy","doi":"10.1016/j.psychres.2024.116345","DOIUrl":"10.1016/j.psychres.2024.116345","url":null,"abstract":"Dissociative symptoms are a frequent complication in posttraumatic stress disorders affecting about a third of all PTSD patients. While theoretical models predict a physiological hypoarousal during posttraumatic dissociations, empirical evidence is lacking. We addressed this by studying spontaneously occurring dissociative symptoms and related heart rate changes in an ecological momentary assessment. Therefore, we continuously measured heart rate for five to ten days with mobile ECG in 47 female inpatients diagnosed with posttraumatic stress disorder and dissociative symptoms. During this observation period, patients tracked each dissociative event on a smartphone app and reported on symptom characteristics. Patients reported a total of 164 dissociative events. Those typically lasted <30 min and involved co-occuring depersonalization and derealization of moderate to severe intensity. Tracked symptoms correlated positively with some conventional self-reports for depersonalization and derealization. Heart rate during dissociative symptoms varied greatly between and within individuals and was on average not different from baseline assessment. There was also no significant relation between dissociation intensity and heart rate change. These results challenge the theory of reactive hypoarousal during chronic dissociation and support the view that physiological adaptation modifies in the course of posttraumatic chronification. They also highlight the individual variability of dissociative symptoms and underscore the necessity of detailed assessment for targeted therapeutic approaches.","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"116345"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative efficacy of multiple non-invasive brain stimulation to treat major depressive disorder in older patients: A systematic review and network meta-analysis study based on randomized controlled trials. 多次无创脑刺激治疗老年患者重度抑郁症的比较疗效：基于随机对照试验的系统评价和网络荟萃分析研究

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-12-27 DOI: 10.1016/j.psychres.2024.116340

Yang Yang, Jianglin Chen, Min Yu, Cheng Xiong, Rong Zhang, Guohui Jiang

{"title":"Comparative efficacy of multiple non-invasive brain stimulation to treat major depressive disorder in older patients: A systematic review and network meta-analysis study based on randomized controlled trials.","authors":"Yang Yang, Jianglin Chen, Min Yu, Cheng Xiong, Rong Zhang, Guohui Jiang","doi":"10.1016/j.psychres.2024.116340","DOIUrl":"10.1016/j.psychres.2024.116340","url":null,"abstract":"Background: Major depressive disorder (MDD) is prevalent among older patients and is frequently associated with cognitive decline and a reduced quality of life. Non-invasive brain stimulation (NIBS) techniques show promise for treating MDD, but their comparative efficacy and safety older populations remain unclear. This study aimed to compare the efficacy and cognitive effects of various NIBS techniques in treating MDD in older patients.Methods: We searched the PubMed, EMBASE, Cochrane Library, and Web of Science core databases from inception to March 2024. Seventeen randomized controlled trials (RCTs) were included.Results: Surfaces under the cumulative ranking curve (SUCRA) values were used to rank the interventions. The SUCRA rankings for the Hamilton Depression Rating Scale (HDRS) outcomes indicated that repetitive transcranial magnetic stimulation (rTMS) (89.0 %) had the highest efficacy, followed by transcranial direct current stimulation (tDCS) (68.7 %). rTMS demonstrated significantly superior efficacy compared with bilateral electroconvulsive therapy (BL ECT) and right unilateral electroconvulsive therapy (RUL ECT). Theta burst stimulation (TBS) had the highest response rate (69.6 %), followed by rTMS (61.8 %). Based on the Mini-Mental State Examination, rTMS (86.4 %) ranked the highest, with RUL ECT showing significantly better outcomes than BL ECT.Conclusion: NIBS, particularly rTMS and TBS, may offer effective treatment options for older patients with MDD. Further research with larger sample sizes and longer follow-up periods is required to validate these findings and inform clinical practice.","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"116340"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unipolar mania over the course of a 15-year follow-up study. 一项为期15年的随访研究。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-12-30 DOI: 10.1016/j.psychres.2024.116348

Hua-Meng Shi, De-Gua Jiang

{"title":"Unipolar mania over the course of a 15-year follow-up study.","authors":"Hua-Meng Shi, De-Gua Jiang","doi":"10.1016/j.psychres.2024.116348","DOIUrl":"10.1016/j.psychres.2024.116348","url":null,"abstract":"Objective: A proportion of patients with bipolar disorder (BD) manifests with only Unipolar mania (UM). We conducted a follow-up study of patients diagnosed with Unipolar mania and compared them as a group if they had a mild depressive episode with those who did not.Method: 248 subjects were prospectively followed-up to 15 years. During the 15-year follow-up study, Pure mania was defined as patients who did not experience mild depressive episodes(203) and Mania with mild depression was defined as patients who did experience mild depressive episodes(45). Then, we compare characterization of clinical features between Pure mania (PM) and Mania with mild depression (MMD).Results: Compared with the Mania with mild depression group, the Pure mania group had more psychotic symptoms, fewer suicidal behaviors, a higher proportion of morningness chronotype, better sleep quality, higher extraversion, lower neuroticism, and less harm avoidance personality traits. Substantially different lifetime comorbidity patterns were observed between the two groups.Conclusion: Patients with Pure mania exhibited distinct clinical and psychosocial features compared with patients with the Mania with mild depression. Further studies are warranted to investigate the underlying mechanisms for diverse presentations in subgroups of BDs.Limitations: These results apply to a relatively short outcome period, and the sample size is relatively small.","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"116348"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142953998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI in substance use recovery: Innovation or risk? A call for caution. 人工智能在药物使用康复中的应用：创新还是风险？请谨慎行事。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-09-13 DOI: 10.1016/j.psychres.2024.116193

Erfan Ramadhani, Ramtia Darma Putri, Vasco Delano, M Taheri Akhbar, Erdiansyah Erdiansyah, Muhammad Kurniawan

引用次数: 0

Maternal vitamin B12 during pregnancy and schizophrenia in offspring. 孕期母体维生素 B12 与后代的精神分裂症。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-11-30 DOI: 10.1016/j.psychres.2024.116284

Andre Sourander, Sanju Silwal, Heljä-Marja Surcel, Susanna Hinkka-Yli-Salomäki, Keely Cheslack-Postava, Subina Upadhyaya, Ian W McKeague, Alan S Brown

{"title":"Maternal vitamin B12 during pregnancy and schizophrenia in offspring.","authors":"Andre Sourander, Sanju Silwal, Heljä-Marja Surcel, Susanna Hinkka-Yli-Salomäki, Keely Cheslack-Postava, Subina Upadhyaya, Ian W McKeague, Alan S Brown","doi":"10.1016/j.psychres.2024.116284","DOIUrl":"10.1016/j.psychres.2024.116284","url":null,"abstract":"Background: Maternal nutritional deficiency is linked with several adverse outcomes in offspring but the link between maternal vitamin B12 levels and offspring schizophrenia remains unexplored.Methods: In this nationwide population-based nested case-control design, 1145 schizophrenia cases were born between 1987-1997 and diagnosed by 2017 and each case were matched with a control. Maternal vitamin B12 levels during the first and early second trimesters of pregnancy were measured using chemiluminescence microparticle immunoassay from maternal sera. Conditional logistic regression was used to examine the association between maternal vitamin B12 levels and offspring schizophrenia.Results: Low maternal vitamin B12 levels were not associated with offspring schizophrenia in unadjusted (OR 1.04, 95% CI 0.88-1.24) or adjusted analyses (aOR 1.14, 95% CI 0.95-1.37). When analyzed by quintiles, no significant association was observed between the lowest versus highest quintile of maternal vitamin B12 levels and schizophrenia in unadjusted (OR 1.01, 95% CI 0.78-1.30) or adjusted analyses (OR 0.89, 95% CI 0.68-1.17).Conclusion: Maternal vitamin B12 levels in early pregnancy were not associated with offspring schizophrenia. Future studies measuring both genetic and environmental factors are required to elucidate the role of maternal vitamin B12 deficiency in schizophrenia and its potential pathways to influence schizophrenia in offspring.","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"116284"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19's silent scars: The urgent link between SARS-CoV-2 infection and long-term mental health consequences. COVID-19 的无声伤疤：SARS-CoV-2感染与长期精神健康后果之间的紧急联系。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-12-10 DOI: 10.1016/j.psychres.2024.116322

Yun Xie, Jiajun Wu, Shun Zhu, Ruilan Wang

引用次数: 0

Autism spectrum disorder and anorexia nervosa: Investigating the behavioural and neurocognitive overlap. 自闭症谱系障碍和神经性厌食症：行为和神经认知重叠的研究。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-11-27 DOI: 10.1016/j.psychres.2024.116285

M Kirkovski, G Papavasiliou, B E Speranza, J Scarfo, N Albein-Urios, J Linardon, A Phillipou, M Fuller-Tyszkiewicz, P G Enticott

{"title":"Autism spectrum disorder and anorexia nervosa: Investigating the behavioural and neurocognitive overlap.","authors":"M Kirkovski, G Papavasiliou, B E Speranza, J Scarfo, N Albein-Urios, J Linardon, A Phillipou, M Fuller-Tyszkiewicz, P G Enticott","doi":"10.1016/j.psychres.2024.116285","DOIUrl":"10.1016/j.psychres.2024.116285","url":null,"abstract":"Autism spectrum disorder (autism) and anorexia nervosa (AN) share many clinical features. Two key neurocognitive correlates of the autistic dyad, specifically, mentalising (social impairment) and set-shifting (restricted and repetitive behaviours/interests [RRBI]) were investigated in a sample of 327 adult participants with autism (n = 100; 50 females, 50 male), AN (n = 82; 54 females, 28 male), autism and AN (n = 45; 36 females, 9 male), and 100 (50 female, 50 male) control participants from the general population. A battery of self-report (Autism Spectrum Quotient, Eating Disorder Examination Questionnaire, Reflective Function Questionnaire, and Repetitive Behaviour Questionnaire 2 - Adult version) and performance-based (Wisconsin Card Sort Task [WCST] and Penn Emotion Recognition Test [ER-40]) measures were administered online. Clinical participants reported greater mentalising difficulty, more repetitive behaviour, and displayed worse mentalising ability compared to controls, with no difference between the clinical groups. Eating disorder psychopathology predicted error (total and perseverative) rates on the WCST, while lower levels of autistic traits were positively associated with ER-40 accuracy. We provide evidence that clinical features of autism and AN might have specific neurocognitive relevance. Improved understanding of the mechanisms underlying the overlapping features of autism and AN can have critical implications for early detection and improved and tailored intervention.","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"116285"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Latent classes of acute grief reactions in the shadow of collective trauma and its predictors in bereaved adults. 丧亲成人集体创伤阴影下急性悲伤反应的潜在类别及其预测因子。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-12-16 DOI: 10.1016/j.psychres.2024.116331

Yaira Hamama-Raz, Menachem Ben-Ezra, Yafit Levin

{"title":"Latent classes of acute grief reactions in the shadow of collective trauma and its predictors in bereaved adults.","authors":"Yaira Hamama-Raz, Menachem Ben-Ezra, Yafit Levin","doi":"10.1016/j.psychres.2024.116331","DOIUrl":"10.1016/j.psychres.2024.116331","url":null,"abstract":"The current study explored grief reaction profiles after the October 7th, 2023, Israeli massacre regarding the loss of significant others. It investigated factors worsening pre-existing grief in 2,028 adult civilians, with 1,263 reporting pre- or post-massacre loss. Participants completed self-reports on prolonged grief disorder (PGD), post-traumatic stress disorder (PTSD), complex PTSD (CPTSD), cognitive emotional regulation (CER), and assumptive worldviews. Latent class analysis identified four classes of probable PGD among those with lifetime loss: \"high PGD-both core and emotional pain\" (35.9 %); \"Medium PGD-emotional pain\" (6.9 %); \"medium to high PGD-high core, medium emotional pain\" (23 %); and \"low PGD-both core and emotional pain\" (34.5 %). The subsample analysis of individuals experiencing lifetime loss with concurrent October 7th loss indicated three classes of probable PGD: \"high PGD symptoms\" (47.9 %), \"high to medium PGD-high core with medium emotional pain symptoms\" (15.9 %), and \"low PGD symptoms\" (36.2 %). The subsample analysis of those who experienced concurrent recent loss related to the October 7th attack showed two classes related to indicative of acute grief: \"high PGD symptoms\" (69 %), and \"low PGD symptoms\" (31 %). Negative CER coping strategies were associated significantly with the high PGD in all three groups, and with increased risk of PTSD and CPTSD symptoms compared to the \"low PGD symptoms\" group. Collective bereavement amid collective trauma can activate prior individual grief reactions, even without current losses from the traumatic event. Those experiencing loss tied to severe traumatic events may face higher susceptibility to developing pathological grief.","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"116331"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative administration of esketamine during cesarean section is a double-edged sword. 在剖腹产手术中围手术期使用艾司氯胺酮是一把双刃剑。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-12-09 DOI: 10.1016/j.psychres.2024.116321

Takahiko Nagamine

引用次数: 0

Efficacy of bright light therapy improves outcomes of perinatal depression: A systematic review and meta-analysis of randomized controlled trials. 亮光治疗改善围产期抑郁症的疗效：随机对照试验的系统回顾和荟萃分析。

IF 4.2 2区医学

Psychiatry Research Pub Date : 2025-02-01 Epub Date: 2024-12-06 DOI: 10.1016/j.psychres.2024.116303

Lian Du, Jinkun Zeng, Hua Yu, Bijun Chen, Wei Deng, Tao Li

{"title":"Efficacy of bright light therapy improves outcomes of perinatal depression: A systematic review and meta-analysis of randomized controlled trials.","authors":"Lian Du, Jinkun Zeng, Hua Yu, Bijun Chen, Wei Deng, Tao Li","doi":"10.1016/j.psychres.2024.116303","DOIUrl":"10.1016/j.psychres.2024.116303","url":null,"abstract":"The efficacy of bright light therapy (BLT) in the context of perinatal depression remains underexplored. This meta-analysis aimed to systematically assess the effectiveness of BLT among perinatal depression. A comprehensive literature search was performed across several databases, including the Cochrane Central Register of Controlled Trials, PubMed, Embase, CNKI and the clinical trials registry platform, covering the period from the inception of each database up to January 2024. The Cochrane Collaboration's bias assessment tool was employed to evaluate the quality of the included studies. Review Manager 5.3 Software was utilized to conduct the meta-analysis. Six trials, encompassed a total of 167 participants diagnosed with perinatal depression were incorporated quantitative analysis, all of those have been published in English, with no restriction on publication year, and used BLT and dim light therapy (DLT) as intervention. The relative risk (RR) of BLT compared to DLT for perinatal depression is 1.46 (fixed effects model, p = 0.04, 95 % CI = [1.02, 2.10]), indicating a significant improvement in depression outcomes compared to DLT groups. The heterogeneity test yielded an I2 value of 41 % (p = 0.13), indicated a low degree of heterogeneity. Considering the small sample size, we conducted a sensitivity analysis, found RR increased to 2.33 (fixed effects model, p = 0.001, CI = 1.39-3.92). Cochrane Risk of Bias Tool showed only a single study was deemed high quality. This study indicates a beneficial impact of BLT on perinatal depression, subgroup analysis finds no significant mediation effects of different parameters after sensitivity analyses. It is recommended that future studies with larger samples be conducted to explore the effects of BLT on perinatal depression.","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"344 ","pages":"116303"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0