Lei Yang , Yiping Nan , Jie Zhou , Jingwen Sun , Lanting Huo , Fang Liu , Duolao Wang , Atif Rahman , Xiaomei Li
{"title":"护士辅助的数字思维健康项目对产后抑郁症的有效性:一项随机对照试验","authors":"Lei Yang , Yiping Nan , Jie Zhou , Jingwen Sun , Lanting Huo , Fang Liu , Duolao Wang , Atif Rahman , Xiaomei Li","doi":"10.1016/j.psychres.2025.116639","DOIUrl":null,"url":null,"abstract":"<div><div><strong>Background:</strong> Postpartum depression (PPD) is a prevalent mental health issue with significant adverse consequences for both mothers and their infants. The Thinking Healthy Program (THP) is an effective intervention for perinatal depression in non-specialized healthcare settings. This study aimed to evaluate the effectiveness of a nurse-assisted digital THP in treating PPD among postpartum women experiencing elevated depression symptoms in China based on elevated Edinburgh Postnatal Depression Scale (EPDS) scores through a randomized controlled trial.</div><div><strong>Methods:</strong> Postpartum women experiencing elevated depression symptoms were recruited and randomly assigned to either a six-week nurse-assisted digital THP intervention group or a treatment-as-usual control group using computer-generated random sequences. The primary outcome was self-reported depression symptoms measured by the EPDS. Secondary outcomes included general health status (Five-level EuroQol 5-Dimensions Questionnaire), mother-infant attachment (Maternal Postnatal Attachment Scale), and perceived social support (Multidimensional Scale of Perceived Social Support). Measurements were conducted online at baseline, post-intervention, and at a three-month follow-up.</div><div><strong>Results:</strong> A total of 120 postpartum women were allocated to either the intervention (<em>n</em> = 60) or the control (<em>n</em> = 60) group. Participants in the intervention group showed a greater reduction in depression symptoms compared to the control group at post-intervention (β=-1.70, <em>P</em> = 0.047) and at three-month follow-up (β=-1.90, <em>P</em> = 0.007). However, there were no significant effects on general health status. The intervention also led to significantly greater improvements in mother-infant attachment (β=3.05, <em>P</em> = 0.006) and perceived social support at post-intervention (β=6.52, <em>P</em> = 0.027) and at three-month follow-up (β=6.96, <em>P</em> = 0.015).</div><div><strong>Conclusions:</strong> Our results suggest that the nurse-assisted digital THP intervention is effective in reducing maternal depression levels, enhancing mother-infant attachment and increasing perceived social support. Delivering THP via mobile apps is feasible, and nurse assistance can facilitate postpartum women's acceptance of digital psychological interventions.</div></div>","PeriodicalId":20819,"journal":{"name":"Psychiatry Research","volume":"351 ","pages":"Article 116639"},"PeriodicalIF":4.2000,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effectiveness of a nurse-assisted digital thinking healthy program for postpartum depression: A randomized controlled trial\",\"authors\":\"Lei Yang , Yiping Nan , Jie Zhou , Jingwen Sun , Lanting Huo , Fang Liu , Duolao Wang , Atif Rahman , Xiaomei Li\",\"doi\":\"10.1016/j.psychres.2025.116639\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><strong>Background:</strong> Postpartum depression (PPD) is a prevalent mental health issue with significant adverse consequences for both mothers and their infants. The Thinking Healthy Program (THP) is an effective intervention for perinatal depression in non-specialized healthcare settings. This study aimed to evaluate the effectiveness of a nurse-assisted digital THP in treating PPD among postpartum women experiencing elevated depression symptoms in China based on elevated Edinburgh Postnatal Depression Scale (EPDS) scores through a randomized controlled trial.</div><div><strong>Methods:</strong> Postpartum women experiencing elevated depression symptoms were recruited and randomly assigned to either a six-week nurse-assisted digital THP intervention group or a treatment-as-usual control group using computer-generated random sequences. The primary outcome was self-reported depression symptoms measured by the EPDS. Secondary outcomes included general health status (Five-level EuroQol 5-Dimensions Questionnaire), mother-infant attachment (Maternal Postnatal Attachment Scale), and perceived social support (Multidimensional Scale of Perceived Social Support). Measurements were conducted online at baseline, post-intervention, and at a three-month follow-up.</div><div><strong>Results:</strong> A total of 120 postpartum women were allocated to either the intervention (<em>n</em> = 60) or the control (<em>n</em> = 60) group. Participants in the intervention group showed a greater reduction in depression symptoms compared to the control group at post-intervention (β=-1.70, <em>P</em> = 0.047) and at three-month follow-up (β=-1.90, <em>P</em> = 0.007). However, there were no significant effects on general health status. The intervention also led to significantly greater improvements in mother-infant attachment (β=3.05, <em>P</em> = 0.006) and perceived social support at post-intervention (β=6.52, <em>P</em> = 0.027) and at three-month follow-up (β=6.96, <em>P</em> = 0.015).</div><div><strong>Conclusions:</strong> Our results suggest that the nurse-assisted digital THP intervention is effective in reducing maternal depression levels, enhancing mother-infant attachment and increasing perceived social support. Delivering THP via mobile apps is feasible, and nurse assistance can facilitate postpartum women's acceptance of digital psychological interventions.</div></div>\",\"PeriodicalId\":20819,\"journal\":{\"name\":\"Psychiatry Research\",\"volume\":\"351 \",\"pages\":\"Article 116639\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2025-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Psychiatry Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0165178125002872\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychiatry Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165178125002872","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
摘要
背景:产后抑郁症(PPD)是一种普遍存在的心理健康问题,对母亲和婴儿都有严重的不良后果。思考健康计划(THP)是一个有效的干预围产期抑郁症在非专业医疗机构。本研究旨在通过一项随机对照试验,基于爱丁堡产后抑郁量表(EPDS)评分升高,评估护士辅助的数字THP治疗中国产后抑郁症状升高妇女PPD的有效性。方法:招募出现抑郁症状加重的产后妇女,并随机分配到为期六周的护士辅助数字THP干预组或使用计算机生成的随机序列照常治疗的对照组。主要结果是由EPDS测量的自我报告的抑郁症状。次要结局包括一般健康状况(五级EuroQol五维度问卷)、母婴依恋(产妇产后依恋量表)和感知社会支持(感知社会支持多维量表)。在基线、干预后和三个月的随访中进行在线测量。结果:120名产后妇女被分为干预组(n = 60)和对照组(n = 60)。干预组的参与者在干预后(β=-1.70, P = 0.047)和三个月的随访(β=-1.90, P = 0.007)表现出比对照组更大的抑郁症状减轻。然而,对一般健康状况没有显著影响。干预后(β=6.52, P = 0.027)和三个月随访(β=6.96, P = 0.015)的母婴依恋(β=3.05, P = 0.006)和感知社会支持显著改善。结论:护士辅助的数字THP干预在降低母亲抑郁水平、增强母婴依恋和增加感知社会支持方面是有效的。通过移动应用程序提供THP是可行的,护士的协助可以促进产后妇女接受数字心理干预。
The effectiveness of a nurse-assisted digital thinking healthy program for postpartum depression: A randomized controlled trial
Background: Postpartum depression (PPD) is a prevalent mental health issue with significant adverse consequences for both mothers and their infants. The Thinking Healthy Program (THP) is an effective intervention for perinatal depression in non-specialized healthcare settings. This study aimed to evaluate the effectiveness of a nurse-assisted digital THP in treating PPD among postpartum women experiencing elevated depression symptoms in China based on elevated Edinburgh Postnatal Depression Scale (EPDS) scores through a randomized controlled trial.
Methods: Postpartum women experiencing elevated depression symptoms were recruited and randomly assigned to either a six-week nurse-assisted digital THP intervention group or a treatment-as-usual control group using computer-generated random sequences. The primary outcome was self-reported depression symptoms measured by the EPDS. Secondary outcomes included general health status (Five-level EuroQol 5-Dimensions Questionnaire), mother-infant attachment (Maternal Postnatal Attachment Scale), and perceived social support (Multidimensional Scale of Perceived Social Support). Measurements were conducted online at baseline, post-intervention, and at a three-month follow-up.
Results: A total of 120 postpartum women were allocated to either the intervention (n = 60) or the control (n = 60) group. Participants in the intervention group showed a greater reduction in depression symptoms compared to the control group at post-intervention (β=-1.70, P = 0.047) and at three-month follow-up (β=-1.90, P = 0.007). However, there were no significant effects on general health status. The intervention also led to significantly greater improvements in mother-infant attachment (β=3.05, P = 0.006) and perceived social support at post-intervention (β=6.52, P = 0.027) and at three-month follow-up (β=6.96, P = 0.015).
Conclusions: Our results suggest that the nurse-assisted digital THP intervention is effective in reducing maternal depression levels, enhancing mother-infant attachment and increasing perceived social support. Delivering THP via mobile apps is feasible, and nurse assistance can facilitate postpartum women's acceptance of digital psychological interventions.
期刊介绍:
Psychiatry Research offers swift publication of comprehensive research reports and reviews within the field of psychiatry.
The scope of the journal encompasses:
Biochemical, physiological, neuroanatomic, genetic, neurocognitive, and psychosocial determinants of psychiatric disorders.
Diagnostic assessments of psychiatric disorders.
Evaluations that pursue hypotheses about the cause or causes of psychiatric diseases.
Evaluations of pharmacologic and non-pharmacologic psychiatric treatments.
Basic neuroscience studies related to animal or neurochemical models for psychiatric disorders.
Methodological advances, such as instrumentation, clinical scales, and assays directly applicable to psychiatric research.