Radiologia Medica最新文献

{"title":"SIRM/SIC consensus document on the management of patients with acute chest pain.","authors":"Antonio Esposito, Riccardo Faletti, Anna Palmisano, Marco Gatti, Sara Seitun, Cesare Mantini, Piergiuseppe Agostoni, Daniele Andreini, Francesco Barillà, Andrea Barison, Paolo Calabrò, Matteo Cameli, Scipione Carerj, Carlo Catalano, Marcello Chiocchi, Marco Matteo Ciccone, Antonio Curcio, Fabrizio D'Ascenzo, Serena Dell'Aversana, Fabio Falzea, Marco Francone, Nicola Galea, Andrea Giovagnoni, Marco Guglielmo, Andrea Laghi, Carlo Liguori, Luigi Lovato, Riccardo Marano, Rocco Antonio Montone, Doralisa Morrone, Luigi Natale, Savina Nodari, Michele Oppizzi, Stefania Paolillo, Alberto Polimeni, Gianluca Pontone, Italo Porto, Silvia Pradella, Vincenzo Russo, Vincenzo Russo, Luca Saba, Gianfranco Sinagra, Massimo Slavich, Carmen Spaccarotella, Davide Tore, Davide Vignale, Carmine Dario Vizza, Saverio Muscoli, Pasquale Perrone Filardi, Ciro Indolfi","doi":"10.1007/s11547-025-02076-x","DOIUrl":"https://doi.org/10.1007/s11547-025-02076-x","url":null,"abstract":"<p><p>Acute chest pain is a common and challenging reason for emergency department visits and requires prompt and systematic evaluation to address potential life-threatening conditions, minimize risks and manage emergency department overcrowding. This updated consensus statement outlines the appropriate management of patients presenting to the emergency department with acute chest pain, emphasizing the timing and utility of non-invasive advanced imaging (particularly coronary computed tomography angiography) aiming to improve rapid and accurate diagnosis of both cardiac or non-cardiac causes improving patient safety, outcomes, and resource utilization efficiency. The writing committee was composed of members and experts from both the Italian Society of Cardiology (SIC) and the Italian Society of Medical and Interventional Radiology (SIRM) who worked jointly to create a cohesive approach in the field of acute chest pain. This structured approach may streamline diagnostic workflows in the emergency setting and support earlier, more appropriate patient management.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arterial-phase mucosal linear enhancement as an indicator of pathological complete response after immunotherapy in pMMR/MSS locally advanced rectal cancer.","authors":"Jingjing Liu, Gengyun Miao, Wentao Tang, Lamei Deng, Shengxiang Rao, Mengsu Zeng, Liheng Liu","doi":"10.1007/s11547-025-02099-4","DOIUrl":"https://doi.org/10.1007/s11547-025-02099-4","url":null,"abstract":"<p><strong>Purpose: </strong>Immunotherapy-based neoadjuvant chemoradiotherapy (iNCRT) has recently emerged for proficient mismatch repair/microsatellite stable (pMMR/MSS) locally advanced rectal cancer (LARC). Accurate identification of pathological complete response for primary tumor (ptPCR) post-treatment is critical for selecting patients eligible for watch-and-wait strategies. This study aimed to evaluate arterial-phase mucosal linear enhancement (AMLE) on contrast-enhanced T1-weighted imaging (CE-T1WI) for predicting ptPCR after iNCRT in pMMR/MSS LARC, compared to conventional T2-weighted/diffusion-weighted imaging (T2DWI) and rectal endoscopy.</p><p><strong>Methods: </strong>This retrospective study included patients with pMMR/MSS LARC who underwent total mesorectal excision after iNCRT between July 2022 and Oct 2024 at a tertiary referral academic center. Preoperative re-staging examinations were rectal endoscopy and MRI, included T2DWI and arterial-phase CE-T1WI for primary tumor assessment. Baseline and post-therapy features associated with ptPCR were identified using univariate and multivariable regression analysis. Diagnostic performance of endoscopy and different MRI protocols to identify ptPCR after iNCRT was evaluated using ROC curves.</p><p><strong>Results: </strong>In total, 75 patients (mean age, 57 years ± 10 [SD]; 54 male patients) were assessed. At histopathology, 29 patients achieved ptPCR. AMLE was more common in the ptPCR group than in the non-ptPCR group after iNCRT (75.9% vs 15.2%, respectively; P < 0.001). AMLE was associated with higher odds of ptPCR in the multivariable regression analysis (odds ratio, 19.14; 95% CI 4.03, 90.87; P = 0.001). And AMLE exhibited the best diagnostic performance in identifying ptPCR after iNCRT, with highest sensitivity, specificity, PPV, NPV, and AUC (0.80; 95% CI 0.70, 0.89).</p><p><strong>Conclusion: </strong>AMLE at CE-TlWI of rectal MRI could be a potential indicator of ptPCR after a new iNCRT in pMMR/MSS LARC, suggesting a relatively credible preoperative evaluation strategy for this group of patients in clinical practice to accurately exclude residual tumors and select watch-and-wait approach, avoiding unnecessary surgery.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy and safety of percutaneous CT-guided pancreatic biopsies.","authors":"Thomas J Vogl, Hamzah Adwan, Leonhard Mann, Ibrahem Al Haj Ibrahem","doi":"10.1007/s11547-025-02087-8","DOIUrl":"https://doi.org/10.1007/s11547-025-02087-8","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the accuracy and safety of CT-guided percutaneous core-needle biopsies of pancreatic lesions suspected to be malignant based on MRI or CT scans.</p><p><strong>Materials and methods: </strong>This retrospective study analyzed CT-guided percutaneous biopsies of suspicious pancreatic lesions performed at our university hospital. Biopsy was performed using a 17G coaxial needle and an 18G core biopsy needle. Data on patient characteristics, lesions, procedures, and histologic results were recorded.</p><p><strong>Results: </strong>A total of 90 patients (58.9% males, mean age 65 ± 12.2 years) underwent CT-guided percutaneous biopsies. The lesions had a mean size of 36.8 ± 12.2 mm and were predominantly located in the pancreatic head 61.1% (55/90). Technical success was achieved in all biopsies 100% (90/90). Most procedures 96.7% (87/90) were performed using direct access routes, while 3.3% (3/90) required indirect transhepatic or transgastric approaches. Among the biopsies, 65.6% (59/90) confirmed malignancy, with adenocarcinoma as the most common malignant subtype representing 55.6% (50/90) of all cases. The rate of non-malignant findings was 26.7% (24/90) including chronic pancreatitis at a rate of 5.6% (5/90) as well as pancreatic pseudocysts and pancreatic cystadenoma each at a rate of 2.2% (2/90), among others. A total of seven cases were identified as false negatives confirmed, but malignancy was later confirmed after re-biopsy or surgery. The initial diagnostic accuracy was 92.2% (83/90). The rate of major complications was 1.1% (1/90), and a total of two minor complications at a rate of 2.2% were observed.</p><p><strong>Conclusion: </strong>This study shows that CT-guided pancreatic biopsy is a safe procedure with high diagnostic accuracy.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the commentary： Recent topics in musculoskeletal imaging focused on clinical applications of AI: How should radiologists approach and use AI?","authors":"Taiki Nozaki, Masahiro Hashimoto, Daiju Ueda, Shinji Naganawa","doi":"10.1007/s11547-025-02097-6","DOIUrl":"https://doi.org/10.1007/s11547-025-02097-6","url":null,"abstract":"","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evaluation of effectiveness of IL-17 and IL-23 inhibitors on nail and enthesis involvement in early psoriatic arthritis patients by high-frequency ultrasonography: a single-centre prospective proof-of-concept study.","authors":"Piero Ruscitti, Camilla Gianneramo, Pierpaolo Palumbo, Manfredo Bruni, Martina Gentile, Sabrina Lanzi, Emanuele Vagnozzi, Alessia Loda, Lina Maria Magnanimi, Maria Concetta Fargnoli, Antonio Barile, Paola Cipriani, Maria Esposito","doi":"10.1007/s11547-025-02086-9","DOIUrl":"https://doi.org/10.1007/s11547-025-02086-9","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effectiveness of IL-17 and IL-23 inhibitors in psoriatic nail and enthesis involvement by ultrasonography with the use of high-frequency probes (HFUS). To correlate the obtained HFUS findings with disease activity of patients with psoriatic arthritis (PsA).</p><p><strong>Material and methods: </strong>Consecutive early naïve patients with PsA underwent HFUS on nails and entheses before and after 24 weeks of treatment with IL-17 or IL-23 inhibitor. The Brown University Nail Enthesis Scale (BUNES), considering morphometry and Power Doppler (PD), and the Madrid Sonography Enthesitis Index (MASEI) score were used to evaluate these features. HFUS findings were correlated with the extension of the disease on skin by Psoriasis Area and Severity Index (PASI) and joints by Disease Activity Index for Psoriatic Arthritis (DAPSA).</p><p><strong>Results: </strong>Twenty early naïve patients with PsA were treated for 24 weeks with an IL-17 or IL-23 inhibitor. A significant reduction of BUNES PD was observed considering the whole cohort of patients receiving these drugs (p = 0.044), whereas, despite a trend, no significant difference was reported comparing BUNES morphometry. The BUNES PD correlated with PASI (r = 0.466, p = 0.030) and with DAPSA (r = 0.444, p = 0.032), whereas BUNES morphometry did not. A significant reduction of MASEI was observed considering the whole assessed cohort of patients treated with these drugs (p = 0.045). The MASEI correlated with both PASI (r = 0.429, p = 0.037) and DAPSA (r = 0.499, p = 0.017).</p><p><strong>Conclusions: </strong>This proof-of-concept study demonstrated that the assessment by HFUS may provide additional accurate information about the effectiveness of IL-17 and IL-23 inhibitors in psoriatic nail and enthesis involvement.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Deep Learning for Predicting Hematoma Expansion in Intracerebral Hemorrhage Using Computed Tomography Scans: A Systematic Review and Meta-Analysis of Diagnostic Accuracy.","authors":"Amir Mahmoud Ahmadzadeh, Mohammad Amin Ashoobi, Nima Broomand Lomer, Danial Elyassirad, Benyamin Gheiji, Mahsa Vatanparast, Girish Bathla, Long Tu","doi":"10.1007/s11547-025-02089-6","DOIUrl":"https://doi.org/10.1007/s11547-025-02089-6","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to systematically review the studies that utilized deep learning (DL)-based networks to predict hematoma expansion (HE) in patients with intracerebral hemorrhage (ICH) using computed tomography (CT) images.</p><p><strong>Methods: </strong>We carried out a comprehensive literature search across four major databases to identify relevant studies. To evaluate the quality of the included studies, we used both the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) and the METhodological RadiomICs Score (METRICS) checklists. We then calculated pooled diagnostic estimates and assessed heterogeneity using the I² statistic. To assess the sources of heterogeneity, effects of individual studies, and publication bias, we performed subgroup analysis, sensitivity analysis, and Deek's asymmetry test.</p><p><strong>Results: </strong>Twenty-two studies were included in the qualitative synthesis, of which 11 and 6 were utilized for exclusive DL and combined DL meta-analyses, respectively. We found pooled sensitivity of 0.81 and 0.84, specificity of 0.79 and 0.91, positive diagnostic likelihood ratio (DLR) of 3.96 and 9.40, negative DLR of 0.23 and 0.18, diagnostic odds ratio of 16.97 and 53.51, and area under the curve of 0.87 and 0.89 for exclusive DL-based and combined DL-based models, respectively. Subgroup analysis revealed significant inter-group differences according to the segmentation technique and study quality.</p><p><strong>Conclusion: </strong>DL-based networks showed strong potential in accurately identifying HE in ICH patients. These models may guide earlier targeted interventions such as intensive blood pressure control or administration of hemostatic drugs, potentially leading to improved patient outcomes.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"⁶⁸Ga-DOTATATE PET/CT versus MRI in neuroendocrine liver metastases: a comprehensive per-lesion analysis.","authors":"Alexander Herold, Azadeh Hajati, Yihan Cao, Kevin P Fialkowski, Soumyadeep Ghosh, Francis Delaney, Vrushab Gowda, Pedram Heidari, Shadi A Esfahani, Mukesh G Harisinghani, Luigi Asmundo, Lucian Beer, Valeria Peña-Trujillo, Samantha G Harrington, Steven Stufflebeam, Bruce R Rosen, Michael Weber, Susie Y Huang, Onofrio A Catalano","doi":"10.1007/s11547-025-02080-1","DOIUrl":"https://doi.org/10.1007/s11547-025-02080-1","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic performance of ⁶⁸Ga-DOTATATE PET, contrast-enhanced CT, combined DOTATATE PET/CT, and MRI in detecting neuroendocrine liver metastases on a per-lesion basis and to assess the added value of diagnostic contrast-enhanced CT to PET interpretation as well as influence of lesion size.</p><p><strong>Materials and methods: </strong>This retrospective study evaluated patients with histologically-confirmed gastroenteropancreatic neuroendocrine tumors who underwent both contrast-enhanced MRI and ⁶⁸Ga-DOTATATE PET/CT within 12 weeks between August 2017 and December 2023. Three readers evaluated in consensus MRI, ⁶⁸Ga-DOTATATE PET, contrast-enhanced CT, and combined PET/CT in separate sessions. Lesions were stratified by size. Diagnostic performance metrics were calculated using generalized estimating equations with reference standard of imaging follow-up or histopathology.</p><p><strong>Results: </strong>The study included 36 patients (mean age 66.4 ± 10.7 years, 55.6% male) with 720 lesions, of which 582 were metastases. MRI demonstrated superior performance (sensitivity 94.0%, specificity 94.2%) compared to all other modalities (all p < .001). Combined PET/CT showed superior sensitivity (68.1%) compared to PET alone (61.1%) (p < .001). The addition of diagnostic contrast-enhanced CT to PET interpretation identified 41 additional metastases. Size-stratified analysis revealed superior detection of subcentimeter lesions by MRI (sensitivity 83.3% for ≤ 5 mm, 99.6% for 6-10 mm) compared to PET/CT (34.8% and 78.6%, respectively; p < .001). For lesions > 10 mm, both MRI and PET/CT achieved 100% sensitivity, while PET alone reached 94.1% (p = .019).</p><p><strong>Conclusion: </strong>MRI outperforms ⁶⁸Ga-DOTATATE PET/CT in detecting individual neuroendocrine liver metastases, particularly for subcentimeter lesions. While diagnostic CT improves PET performance, the combination of MRI with ⁶⁸Ga-DOTATATE PET/CT provides the most comprehensive assessment.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating dosimetric outcomes: a comparison of CyberKnife, VMAT FFF, and Helical Tomotherapy Radixact for treating localized prostate cancer.","authors":"Gaetano Gagliardo, Marcello Serra, Gianluca Ametrano, Marco Galiero, Cecilia Arrichiello, Valentina Borzillo, Francesca Buonanno, Valentina d'Alesio, Rossella Di Franco, Paolo Muto","doi":"10.1007/s11547-025-02046-3","DOIUrl":"https://doi.org/10.1007/s11547-025-02046-3","url":null,"abstract":"<p><p>Prostate cancer (PCa) remains one of the most frequently diagnosed malignancies in men globally, ranking second in prevalence, with increasing incidence anticipated due to aging populations. Radiotherapy has emerged as a cornerstone treatment for localized PCa with stereotactic body radiation therapy (SBRT), and it offers a promising approach by delivering highly conformal high-dose radiation in fewer fractions. This study compares the dosimetric outcomes of three SBRT techniques-CyberKnife (CK), Volumetric Modulated Arc Therapy with flattening filter-free mode (VMAT FFF), and Helical Tomotherapy Radixact (HT)-for localized PCa. The investigation evaluates dose distribution characteristics, sparing of organs at risk (OARs), and treatment delivery efficiency. Two patient groups with low-to-intermediate-risk localized PCa treated at the Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale were included. Treatment plans for CK, VMAT FFF, and HT were retrospectively generated and analyzed using dosimetric metrics such as Conformity Index (CI), Homogeneity Index (HI), Gradient Index, and dose-volume constraints for OARs. Results revealed comparable target coverage across all techniques, with CK demonstrating superior dose conformity and VMAT FFF achieving shorter treatment times. HT and VMAT FFF are effective alternatives, particularly for centers without access to CK systems, though CK offered advantages in challenging anatomical scenarios. Findings emphasize the feasibility of VMAT FFF and HT as viable options for expanding SBRT accessibility, enabling high-quality treatment delivery in diverse clinical settings.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastatic breast involvement from extramammary malignancies: a review of dissemination pathways, imaging features, and management strategies.","authors":"Luciano Mariano, Luca Nicosia, Antuono Latronico, Filippo Pesapane, Elena Grimaldi, Mauro Borella, Giulia Quercioli, Giovanni Mazzarol, Anna Carla Bozzini, Enrico Cassano","doi":"10.1007/s11547-025-02085-w","DOIUrl":"https://doi.org/10.1007/s11547-025-02085-w","url":null,"abstract":"<p><p>Metastatic involvement (MB) of the breast from extramammary malignancies is rare, with an incidence of 0.09-1.3% of all breast malignancies. Due to its variable clinical and radiological presentation, MB often mimics primary breast cancer (BC), leading to potential misdiagnosis and impacting treatment decisions. This narrative review analysed MB cases based on dissemination pathways: hematogenous (HM), lymphatic (LM), or direct contiguous (DC) spread. HM was the most frequent, particularly in melanoma, lung, renal, and gastrointestinal carcinomas, presenting as well-circumscribed, non-calcified nodules without axillary lymph node involvement, distinguishing them from BC. LM spread, common in HM malignancies, caused diffuse breast oedema, skin thickening, and a \"peau d'orange\" appearance, resembling inflammatory BC. DC spread, though rarer, was observed in advanced lung cancer, with infiltrative lesions extending from the chest wall. Multimodal imaging (Mammography (DM), Ultrasound (US), Magnetic Resonance Imaging (MRI), Computer Tomography (CT), and Positron Emission Tomography (PET)) was critical for detecting MB, while histopathological and immunohistochemical analysis confirmed extramammary origin. Due to the rarity and heterogeneity of MB, diagnosis requires a multidisciplinary approach integrating oncological history, imaging, and pathology. Recognising distinct imaging patterns can aid early diagnosis, avoid unnecessary surgery, and guide appropriate systemic therapy based on the primary malignancy. Early identification of the metastatic pattern may influence clinical management decisions and improve patient outcomes.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Male breast MRI: a review of different pathological conditions.","authors":"Marco Barillari, Piero Zanutto, Francesca Pellini, Elena Fiorio, Giulia Deguidi, Alessandra Invento, Alessia Nottegar, Mirko D'Onofrio, Giancarlo Mansueto","doi":"10.1007/s11547-025-02084-x","DOIUrl":"https://doi.org/10.1007/s11547-025-02084-x","url":null,"abstract":"<p><p>The male breast is predisposed to be affected by many of the same pathological processes as the female breast is. The diagnosis of male breast pathologies is generally achievable when clinical evaluation is combined with standard breast imaging methods such as mammography and ultrasound. Magnetic resonance imaging is also a valuable tool in diagnosing the main pathologies affecting the male breast, especially for evaluating pre- and post-surgical treatments and follow-up. However, although this technique has been sufficiently regulated and adopted by many breast radiologists for female breast imaging, its application in the diagnosis of male breast pathologies remains limited to a few specialized centers. This article, based on a retrospective analysis of the experience of the University of Verona, explores various aspects of male breast diseases, including benign conditions such as gynecomastia and breast implant ruptures in transgender women as well as malignant entities such as male breast cancer. Emphasis is placed on the distinctive morphological features, enhancement patterns and kinetics observed in male breast lesions on dynamic contrast-enhanced MRI. This article provides a comprehensive overview of the application of MRI in male breast disease assessment, highlighting the potential role of MRI as a complementary tool to traditional breast imaging techniques.</p>","PeriodicalId":20817,"journal":{"name":"Radiologia Medica","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}