Accuracy and safety of percutaneous CT-guided pancreatic biopsies.

IF 4.8 1区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiologia Medica Pub Date : 2025-09-19 DOI:10.1007/s11547-025-02087-8

Thomas J Vogl, Hamzah Adwan, Leonhard Mann, Ibrahem Al Haj Ibrahem

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引用次数: 0

Abstract

Purpose: To assess the accuracy and safety of CT-guided percutaneous core-needle biopsies of pancreatic lesions suspected to be malignant based on MRI or CT scans.

Materials and methods: This retrospective study analyzed CT-guided percutaneous biopsies of suspicious pancreatic lesions performed at our university hospital. Biopsy was performed using a 17G coaxial needle and an 18G core biopsy needle. Data on patient characteristics, lesions, procedures, and histologic results were recorded.

Results: A total of 90 patients (58.9% males, mean age 65 ± 12.2 years) underwent CT-guided percutaneous biopsies. The lesions had a mean size of 36.8 ± 12.2 mm and were predominantly located in the pancreatic head 61.1% (55/90). Technical success was achieved in all biopsies 100% (90/90). Most procedures 96.7% (87/90) were performed using direct access routes, while 3.3% (3/90) required indirect transhepatic or transgastric approaches. Among the biopsies, 65.6% (59/90) confirmed malignancy, with adenocarcinoma as the most common malignant subtype representing 55.6% (50/90) of all cases. The rate of non-malignant findings was 26.7% (24/90) including chronic pancreatitis at a rate of 5.6% (5/90) as well as pancreatic pseudocysts and pancreatic cystadenoma each at a rate of 2.2% (2/90), among others. A total of seven cases were identified as false negatives confirmed, but malignancy was later confirmed after re-biopsy or surgery. The initial diagnostic accuracy was 92.2% (83/90). The rate of major complications was 1.1% (1/90), and a total of two minor complications at a rate of 2.2% were observed.

Conclusion: This study shows that CT-guided pancreatic biopsy is a safe procedure with high diagnostic accuracy.

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经皮ct引导下胰腺活检的准确性和安全性。

目的：评价CT引导下经皮穿刺活检对经MRI或CT怀疑为恶性胰腺病变的准确性和安全性。材料和方法：本回顾性研究分析了在我校医院进行的可疑胰腺病变的ct引导下经皮活检。活检采用17G同轴针和18G芯活检针。记录患者特征、病变、手术和组织学结果的数据。结果：90例患者行ct引导下经皮活检，其中男性58.9%，平均年龄65±12.2岁。病变平均大小36.8±12.2 mm，主要位于胰头61.1%（55/90）。所有活检的技术成功率均为100%（90/90）。96.7%（87/90）的手术采用直接入路，3.3%（3/90）的手术采用间接经肝或经胃入路。在活检中，65.6%（59/90）确诊为恶性，腺癌是最常见的恶性亚型，占所有病例的55.6%（50/90）。非恶性发生率为26.7%(24/90)，其中慢性胰腺炎发生率为5.6%(5/90)，胰腺假性囊肿和胰腺囊腺瘤各发生率为2.2%（2/90）。共有7例被确定为假阴性，但后来在重新活检或手术后确诊为恶性肿瘤。初诊正确率为92.2%（83/90）。主要并发症发生率为1.1%(1/90)，次要并发症共2例，发生率为2.2%。结论：本研究表明ct引导胰腺活检是一种安全的方法，诊断准确性高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiologia Medica 医学-核医学

CiteScore

14.10

自引率

7.90%

发文量

133

审稿时长

4-8 weeks

期刊介绍： Felice Perussia founded La radiologia medica in 1914. It is a peer-reviewed journal and serves as the official journal of the Italian Society of Medical and Interventional Radiology (SIRM). The primary purpose of the journal is to disseminate information related to Radiology, especially advancements in diagnostic imaging and related disciplines. La radiologia medica welcomes original research on both fundamental and clinical aspects of modern radiology, with a particular focus on diagnostic and interventional imaging techniques. It also covers topics such as radiotherapy, nuclear medicine, radiobiology, health physics, and artificial intelligence in the context of clinical implications. The journal includes various types of contributions such as original articles, review articles, editorials, short reports, and letters to the editor. With an esteemed Editorial Board and a selection of insightful reports, the journal is an indispensable resource for radiologists and professionals in related fields. Ultimately, La radiologia medica aims to serve as a platform for international collaboration and knowledge sharing within the radiological community.