发布求助
文献互助 智能选刊 最新文献

Protein & Cell最新文献

筛选
英文 中文
MultiKano: an automatic cell type annotation tool for single-cell multi-omics data based on Kolmogorov-Arnold network and data augmentation. MultiKano：基于Kolmogorov-Arnold网络和数据增强的单细胞多组学数据的自动细胞类型标注工具。
IF 13.6 1区 生物学
Protein & Cell Pub Date : 2025-05-28 DOI: 10.1093/procel/pwae069
Siyu Li, Xinhao Zhuang, Songbo Jia, Songming Tang, Liming Yan, Heyang Hua, Yuhang Jia, Xuelin Zhang, Yan Zhang, Qingzhu Yang, Shengquan Chen
{"title":"MultiKano: an automatic cell type annotation tool for single-cell multi-omics data based on Kolmogorov-Arnold network and data augmentation.","authors":"Siyu Li, Xinhao Zhuang, Songbo Jia, Songming Tang, Liming Yan, Heyang Hua, Yuhang Jia, Xuelin Zhang, Yan Zhang, Qingzhu Yang, Shengquan Chen","doi":"10.1093/procel/pwae069","DOIUrl":"10.1093/procel/pwae069","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":" ","pages":"374-380"},"PeriodicalIF":13.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural insights into the distinct ligand recognition and signaling of the chemerin receptors CMKLR1 and GPR1. 趋化素受体CMKLR1和GPR1的独特配体识别和信号传导的结构见解。
IF 13.6 1区 生物学
Protein & Cell Pub Date : 2025-05-28 DOI: 10.1093/procel/pwae073
Xiaowen Lin, Lechen Zhao, Heng Cai, Xiaohua Chang, Yuxuan Tang, Tianyu Luo, Mengdan Wu, Cuiying Yi, Limin Ma, Xiaojing Chu, Shuo Han, Qiang Zhao, Beili Wu, Maozhou He, Ya Zhu
{"title":"Structural insights into the distinct ligand recognition and signaling of the chemerin receptors CMKLR1 and GPR1.","authors":"Xiaowen Lin, Lechen Zhao, Heng Cai, Xiaohua Chang, Yuxuan Tang, Tianyu Luo, Mengdan Wu, Cuiying Yi, Limin Ma, Xiaojing Chu, Shuo Han, Qiang Zhao, Beili Wu, Maozhou He, Ya Zhu","doi":"10.1093/procel/pwae073","DOIUrl":"10.1093/procel/pwae073","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":" ","pages":"381-385"},"PeriodicalIF":13.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Advances in gene and cellular therapeutic approaches for Huntington's disease. 更正：亨廷顿氏病基因和细胞治疗方法的进展。
IF 13.6 1区 生物学
Protein & Cell Pub Date : 2025-05-28 DOI: 10.1093/procel/pwaf005
{"title":"Correction to: Advances in gene and cellular therapeutic approaches for Huntington's disease.","authors":"","doi":"10.1093/procel/pwaf005","DOIUrl":"10.1093/procel/pwaf005","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":" ","pages":"386"},"PeriodicalIF":13.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic implications of synonymous gene recoding: Insights into mechanisms controlling protein biogenesis and activity. 同义基因重新编码的治疗意义：洞察控制蛋白质生物发生和活性的机制。
IF 21.1 1区 生物学
Protein & Cell Pub Date : 2025-05-25 DOI: 10.1093/procel/pwaf028
Brian C Lin,Katarzyna I Jankowska,Upendra K Katneni,Randilu Amarasinghe,Nigam Padhiar,Nobuko Hamasaki-Katagiri,Wells W Wu,Haojie Zhu,Hideki Taguchi,Arnab Ghosh,David D Holcomb,Je-Nie Phue,Sarah E Fumagalli,Darón I Freedberg,Ofer Kimchi,Rong-Fong Shen,Anton A Komar,Zuben E Sauna,Chava Kimchi-Sarfaty
{"title":"Therapeutic implications of synonymous gene recoding: Insights into mechanisms controlling protein biogenesis and activity.","authors":"Brian C Lin,Katarzyna I Jankowska,Upendra K Katneni,Randilu Amarasinghe,Nigam Padhiar,Nobuko Hamasaki-Katagiri,Wells W Wu,Haojie Zhu,Hideki Taguchi,Arnab Ghosh,David D Holcomb,Je-Nie Phue,Sarah E Fumagalli,Darón I Freedberg,Ofer Kimchi,Rong-Fong Shen,Anton A Komar,Zuben E Sauna,Chava Kimchi-Sarfaty","doi":"10.1093/procel/pwaf028","DOIUrl":"https://doi.org/10.1093/procel/pwaf028","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":"16 1","pages":""},"PeriodicalIF":21.1,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The nuclear phosphoinositide-p53 signalosome in the regulation of cell motility. 核磷酸肌醇-p53信号体在细胞运动调节中的作用。
IF 21.1 1区 生物学
Protein & Cell Pub Date : 2025-05-22 DOI: 10.1093/procel/pwaf043
Xiaoting Hou,Yu Chen,Bo Zhou,Fengting Liu,Lingyun Dai,Chunbo Chen,Noah D Carrillo,Vincent L Cryns,Richard A Anderson,Jichao Sun,Mo Chen
{"title":"The nuclear phosphoinositide-p53 signalosome in the regulation of cell motility.","authors":"Xiaoting Hou,Yu Chen,Bo Zhou,Fengting Liu,Lingyun Dai,Chunbo Chen,Noah D Carrillo,Vincent L Cryns,Richard A Anderson,Jichao Sun,Mo Chen","doi":"10.1093/procel/pwaf043","DOIUrl":"https://doi.org/10.1093/procel/pwaf043","url":null,"abstract":"Dysregulation of p53 and phosphoinositide (PIPn) signaling are both key drivers of oncogenesis and metastasis. Our recent findings reveal a previously unrecognized interaction between these pathways, converging in the nucleus to form a PIPn-p53 signalosome that modulates nuclear AKT activation and downstream signaling, thereby influencing cancer cell survival and motility. This review examines recent insights into nuclear PIPn signaling in the context of established roles for p53 in cell dynamics and migration while also deliberating current research on how nuclear PIPns interact with p53 to form signalosomes that affect cell motility. We emphasize the critical role of PIPns in stabilizing p53 and activating de novo nuclear AKT signaling, which subsequently modulates key motility-related pathways. Understanding the unique operation and function of the PIPn-p53 signalosome in nuclear phosphatidylinositol 3-kinase (PI3K)-AKT activation offers novel therapeutic strategies for controlling cancer metastasis by targeting pertinent interactions and events.","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":"31 1","pages":""},"PeriodicalIF":21.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer. 校正：SIRT7作为异染色质稳定剂拮抗人类干细胞衰老。
IF 13.6 1区 生物学
Protein & Cell Pub Date : 2025-05-20 DOI: 10.1093/procel/pwaf031
{"title":"Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer.","authors":"","doi":"10.1093/procel/pwaf031","DOIUrl":"https://doi.org/10.1093/procel/pwaf031","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":" ","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: DJ-1 is dispensable for human stem cell homeostasis. 更正：DJ-1对人类干细胞稳态是不可缺少的。
IF 21.1 1区 生物学
Protein & Cell Pub Date : 2025-05-20 DOI: 10.1093/procel/pwaf034
{"title":"Correction to: DJ-1 is dispensable for human stem cell homeostasis.","authors":"","doi":"10.1093/procel/pwaf034","DOIUrl":"https://doi.org/10.1093/procel/pwaf034","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":"1 1","pages":""},"PeriodicalIF":21.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits. 修正：RBM46对配子发生和影响减数分裂内聚亚基的转录后作用至关重要。
IF 21.1 1区 生物学
Protein & Cell Pub Date : 2025-05-20 DOI: 10.1093/procel/pwaf038
{"title":"Correction to: RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits.","authors":"","doi":"10.1093/procel/pwaf038","DOIUrl":"https://doi.org/10.1093/procel/pwaf038","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":"31 1","pages":""},"PeriodicalIF":21.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration. 更正：单细胞分析揭示了槲皮素在促进头发再生方面的有效作用。
IF 21.1 1区 生物学
Protein & Cell Pub Date : 2025-05-20 DOI: 10.1093/procel/pwaf035
{"title":"Correction to: Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration.","authors":"","doi":"10.1093/procel/pwaf035","DOIUrl":"https://doi.org/10.1093/procel/pwaf035","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":"41 1","pages":""},"PeriodicalIF":21.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasis. 更正：灵长类动物睾丸衰老的单核转录组图谱揭示了精原干细胞储存库的衰竭和支持细胞稳态的丧失。
IF 13.6 1区 生物学
Protein & Cell Pub Date : 2025-05-20 DOI: 10.1093/procel/pwaf033
{"title":"Correction to: A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasis.","authors":"","doi":"10.1093/procel/pwaf033","DOIUrl":"https://doi.org/10.1093/procel/pwaf033","url":null,"abstract":"","PeriodicalId":20790,"journal":{"name":"Protein & Cell","volume":" ","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信