Proceedings of the Nutrition Society最新文献

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Food insecurity in later life: a food security framework to support preventative action. 晚年粮食不安全:支持预防行动的粮食安全框架。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-11-19 DOI: 10.1017/S0029665125102012
Angela Dickinson, Claire Thompson
{"title":"Food insecurity in later life: a food security framework to support preventative action.","authors":"Angela Dickinson, Claire Thompson","doi":"10.1017/S0029665125102012","DOIUrl":"10.1017/S0029665125102012","url":null,"abstract":"<p><p>Longer life expectancy and growing income inequality have prompted an increasing interest in understanding the impact of ageing on nutritional requirements in order to optimise intakes, increase the number of years lived in good health and reduce morbidity and associated health and social care costs. Food insecurity reduces access to nutritious and healthy food. Understanding the evidence base on the impacts of food insecurity and the maintenance of food security for older people is crucial to informing policy and intervention. The increase in numbers of older people experiencing food insecurity is a public health emergency and is associated with under and malnutrition. Food insecurity can be experienced at any stage of the life course but has been more widely studied with families and children where poverty is a major driver. Food insecurity in later life has been less well explored by academics, but differs from that experienced in earlier years due to additional complexities, as physical and cognitive health amplify the impact of poverty. Additionally, factors which can appear to be relatively small in impact can act in a cumulative way to push people towards food insecurity. This review will draw on research about older people's food practices, contexts and experiences in relation to food insecurity in later life and offers a model of food insecurity that has the potential to guide focused public health efforts in order to support the older population to be food secure.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-7"},"PeriodicalIF":4.5,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7618459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145550356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positioning nutritional status in intrinsic capacity monitoring. 定位营养状况内在能力监测。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-11-17 DOI: 10.1017/S0029665125102000
Yuwei Qi, Laura A Schaap, Natasja M van Schoor, Marjolein Visser
{"title":"Positioning nutritional status in intrinsic capacity monitoring.","authors":"Yuwei Qi, Laura A Schaap, Natasja M van Schoor, Marjolein Visser","doi":"10.1017/S0029665125102000","DOIUrl":"10.1017/S0029665125102000","url":null,"abstract":"<p><p>Intrinsic capacity, introduced by the WHO, represents a shift in focus from treating disease to maintaining physical and mental capacities individuals as they age. It encompasses five interrelated domains: vitality, sensory, cognition, psychology, and locomotion. Vitality refers to the body's physiological reserve and is shaped by processes such as energy metabolism, immune function, and neuromuscular integrity. By definition, vitality is closely linked to nutritional status, which plays a central role in maintaining resilience and health in older adults. However, integrating nutritional status into the vitality domain presents several challenges due to inconsistent definitions and varied measurement approaches. This review examines these challenges and explores possibilities for integrating nutritional status in the vitality domain. The absence of standardised nutrition-related indicators limits comparability across studies and constrains the practical application of intrinsic capacity in both research and clinical contexts. To strengthen the role of intrinsic capacity in nutritional monitoring, it is essential to reach consensus on which nutritional indicators to include and how to score them consistently. Addressing these methodological challenges will support the use of intrinsic capacity in identifying early signs of nutritional decline and guiding timely interventions to promote healthy ageing.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-5"},"PeriodicalIF":4.5,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Mediterranean diet and cardiometabolic risk factors: a review of effects and contextual influences. 地中海饮食和心脏代谢危险因素——影响和环境影响的综述。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-11-03 DOI: 10.1017/S0029665125101869
Amber Parry-Strong, Kay M Harper, Fiona E Lithander, Andrea Braakhuis, Jeremy Krebs
{"title":"The Mediterranean diet and cardiometabolic risk factors: a review of effects and contextual influences.","authors":"Amber Parry-Strong, Kay M Harper, Fiona E Lithander, Andrea Braakhuis, Jeremy Krebs","doi":"10.1017/S0029665125101869","DOIUrl":"10.1017/S0029665125101869","url":null,"abstract":"<p><p>The Mediterranean Diet (Med Diet) has long been shown to be associated with lower cardiovascular mortality in epidemiological studies. However, the direct effect of the dietary pattern on cardiovascular risk factors is less clear. Furthermore, the effect of Med Diet interventions in non-Mediterranean populations on cardiovascular and metabolic risk is variable. A Cochrane Review in 2019 concluded there was low to moderate evidence of a modest benefit but noted that there were still ongoing trials. Since 2019, there have been a number of published trials that have not shown a benefit of the Med Diet over other interventions or usual care. It is possible that dietary factors such as quality or quantity of carbohydrate and energy restriction are more important factors, along with the degree of weight loss, than the Med Diet itself. There are also many other factors that influence the uptake and effectiveness of the Med Diet in populations that have a different traditional or habitual diet. This review paper examines a selection of 20 Med Diet intervention trials specifically looking at clinical outcomes of glucose metabolism: fasting plasma glucose, HbA1c, development of type 2 diabetes or need for hypoglycaemic medications, with or without other cardiometabolic risk factors. These trials are a mix of randomised controlled trials, crossover studies and cohort studies of greater than 8 weeks duration with more than 25 participants. There is heterogeneity in study designs and outcomes, making comparison difficult, but there is no clear benefit of the Med Diet presented.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-12"},"PeriodicalIF":4.5,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ecological nutrition: a paradigm shift to transform nutrition research and policymaking for healthy and sustainable diets. 生态营养:将营养研究和政策制定转变为健康和可持续饮食的范式转变。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-10-27 DOI: 10.1017/S0029665125101857
Mark A Lawrence
{"title":"Ecological nutrition: a paradigm shift to transform nutrition research and policymaking for healthy and sustainable diets.","authors":"Mark A Lawrence","doi":"10.1017/S0029665125101857","DOIUrl":"10.1017/S0029665125101857","url":null,"abstract":"<p><p>Dietary patterns are prerequisites for health and integral components of ecological systems. For over a century researchers have been building a body of evidence of associations between dietary patterns and health and sustainability outcomes while policymakers have been synthesising and translating this evidence into policies to promote public health. During this period, food systems have dramatically changed and driven the emergence of food supplies and dietary behaviours with no ecological or evolutionary precedent. Now, the relevance of conventional nutrition research and policymaking approaches for understanding food system transitions and protecting against unhealthy and unsustainable diets is being questioned. This review aims to examine how the ecological nutrition paradigm might guide a transformed approach to nutrition research and policymaking to promote healthy and sustainable diets. It shows the ecological nutrition paradigm is transdisciplinary integrating biological, social and environmental dimensions into nutrition research and policymaking. The paradigm operates to a 'fit-for-purpose' policymaking orientation. It draws on ecological and evolutionary theories to provide insights to conceptualise the causes of, and solutions to, nutrition problems and help design relevant decision-making processes. These research and policymaking features contrast with the 'one-size-fits-all' policymaking orientation and prescriptive decision-making processes of the conventional medical nutrition paradigm. Their attention to a relevance criterion engenders confidence in the likely effectiveness, and ability to avoid unintended consequences, of policies informed within an ecological nutrition paradigm. The review proposes a shift to the ecological nutrition paradigm to transform nutrition research and policymaking for promoting healthy and sustainable diets is overdue.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-10"},"PeriodicalIF":4.5,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145378456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conference on 'Kotahitanga: bridging research, industry and practice'. “哥大希丹加:连接研究、工业和实践”会议。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-10-10 DOI: 10.1017/S0029665125101833
Claire Smith, Pamela von Hurst, Michelle Gibbs, Joanne Todd, Sherly Parackal, Maria Choukri
{"title":"Conference on 'Kotahitanga: bridging research, industry and practice'.","authors":"Claire Smith, Pamela von Hurst, Michelle Gibbs, Joanne Todd, Sherly Parackal, Maria Choukri","doi":"10.1017/S0029665125101833","DOIUrl":"10.1017/S0029665125101833","url":null,"abstract":"<p><p>The 58th Annual Scientific Conference of the Nutrition Society of New Zealand, held in Christchurch in 2024, brought together 187 delegates under the theme 'Kotahitanga: Bridging Research, Industry and Practice'. This theme reflected the society's commitment to uniting diverse sectors to address key nutrition challenges across the life course. Kotahitanga refers to unity and collective action. Topics included nutrition in ageing and chronic disease, infant and toddler nutrition, gut health, sustainable food systems and food safety. Presentations on sarcopenia and Parkinson's disease emphasised the need for greater awareness and tailored nutrition strategies for older adults. The Muriel Bell Lecture celebrated the legacy of New Zealand's first State Nutritionist and called for continued leadership in evidence-based nutrition and encouraged nutritionists to communicate research to the public. A panel on science communication offered practical strategies for engaging the public and countering misinformation. The conference reinforced the importance of collaboration, advocacy and practical application in advancing nutrition.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-3"},"PeriodicalIF":4.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eating well for ageing well: the role of diet and nutrition in promoting healthspan and longevity. 吃得好,老得好-饮食和营养在促进健康和长寿中的作用。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-09-23 DOI: 10.1017/S0029665125101821
Zhaoli Dai
{"title":"Eating well for ageing well: the role of diet and nutrition in promoting healthspan and longevity.","authors":"Zhaoli Dai","doi":"10.1017/S0029665125101821","DOIUrl":"10.1017/S0029665125101821","url":null,"abstract":"<p><p>Healthy ageing and longevity have emerged as urgent public health priorities amid global population ageing and declining birth rates. This review synthesises empirical evidence highlighting the essential role of diet and nutrition in preventing chronic diseases and supporting functional independence in later life. The review was organised using a problem-solving approach to address three core questions: 'What' evidence links food and nutrition with positive health outcomes; 'Why' do specific dietary components affect biological ageing - via mechanisms such as nutrient sensing, inflammation modulation and caloric restriction; and 'How' culturally tailored, person-centred dietary interventions should be developed for better adoption. Findings from centenarian populations suggest that low-energy (i.e. foods with low energy density, such as fruit and vegetables, whole grains), nutrient-rich and diverse diets may help prevent or delay age-related diseases, supporting the notion that food could be used as medicine. Moreover, addressing barriers such as food insecurity and limited access to culturally appropriate healthy food options, particularly in low-income and rural communities, is crucial for achieving equitable health outcomes. Finally, the review calls for integrating personalised nutrition strategies into clinical care and public health initiatives. These efforts can enhance healthspan, improve quality of life and reduce the broader social and economic burdens associated with ageing populations.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-12"},"PeriodicalIF":4.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary recommendations: the role of food-based dietary guidelines, approaches to achieving healthier diets and questions for the future of the Eatwell Guide. 饮食建议:以食物为基础的饮食指南的作用,实现更健康饮食的方法以及对Eatwell指南未来的问题。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-09-22 DOI: 10.1017/S0029665125101791
Louis Levy
{"title":"Dietary recommendations: the role of food-based dietary guidelines, approaches to achieving healthier diets and questions for the future of the Eatwell Guide.","authors":"Louis Levy","doi":"10.1017/S0029665125101791","DOIUrl":"10.1017/S0029665125101791","url":null,"abstract":"<p><p>Personalised nutrition aims to deliver targeted advice to promote dietary behaviours that are beneficial to health based on individual characteristics. Given the financial implications (for providers and participants) of characterising, developing, implementing, communicating and supporting individual behaviour change there remains potential for personalised nutrition to widen health inequalities within populations. Some commentators promote a universal approach to achieve wider population-level benefit. Universal approaches attempt to provide a whole systems perspective with individual outcomes, potentially smaller in scale, impacting at the population level. In the UK the national food-based guidance, the Eatwell Guide, is used to communicate advice on diet consistent with UK government dietary recommendations based on robust, independent assessment of the best available evidence by the Scientific Advisory Committee on Nutrition. Effort was taken in ensuring all UK government recommendations in 2016 (when the UK's national food-based guidance was last reviewed following changes in dietary recommendations on carbohydrates and sugars) could be achieved at a population level based on available and recognised foods. There is evidence that moving towards a diet consistent with national food-based guidelines has positive benefits for health and the environment. There is debate about the cost of a healthy diet and the impact of including elements of sustainability elements. This commentary considers how developments in healthy eating indices may be beneficial as a universal approach could provide opportunities to support individuals move towards healthier diets. It also raises questions about the evidence requirements and timing of any future amendments to the UK's Eatwell Guide.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-4"},"PeriodicalIF":4.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ergothioneine for cognitive health, longevity and healthy ageing: where are we now? 麦角硫因对认知健康、长寿和健康老龄化的影响:我们现在在哪里?
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-09-19 DOI: 10.1017/S0029665125101754
Linda S May-Zhang, Irwin K Cheah, Ian T Zajac, Emily Brindal, Naomi Kakoschke
{"title":"Ergothioneine for cognitive health, longevity and healthy ageing: where are we now?","authors":"Linda S May-Zhang, Irwin K Cheah, Ian T Zajac, Emily Brindal, Naomi Kakoschke","doi":"10.1017/S0029665125101754","DOIUrl":"10.1017/S0029665125101754","url":null,"abstract":"<p><p>As the global population ages, the prevalence of cognitive decline is rising, creating urgent demand for proactive strategies that support brain health and healthy ageing. Ergothioneine, a unique dietary amino-thione absorbed via the OCTN1 transporter, has recently gained attention for its potential as a neuroprotective, longevity-promoting compound. This review synthesizes growing evidence from observational, interventional and mechanistic studies. Observational data consistently associate low blood ergothioneine levels with cognitive impairment, neurodegenerative diseases, cardiovascular disorders, frailty and mortality. Interventional trials in older adults suggest that ergothioneine supplementation may improve cognition, memory, sleep quality and stabilize neurodegeneration biomarkers, with no safety concerns at doses up to 25 mg/day. Mechanistic studies reveal that ergothioneine acts through multiple pathways: mitigating oxidative stress, reducing neuroinflammation, preserving mitochondrial function and potentially modulating neurogenesis and NAD<sup>+</sup> metabolism, although some mechanisms require further investigation. Beyond cognition, ergothioneine shows promise in supporting other physiological systems relevant to ageing, including cardiovascular, metabolic, gut, eye, auditory, liver, kidney, immune, skin and lung health. Together, current evidence positions ergothioneine as a promising nutritional intervention for promoting cognitive resilience and systemic health in ageing, although larger, long-term interventional trials are needed to confirm causality and optimize use.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-15"},"PeriodicalIF":4.5,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of diet on functional dyspepsia: a critical review of current evidence. 饮食对功能性消化不良的影响:对当前证据的批判性回顾。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-09-18 DOI: 10.1017/S0029665125101766
Lucie d'Udekem d'Acoz, Florencia Carbone, Chamara Basnayake, Jessica Biesiekierski
{"title":"The impact of diet on functional dyspepsia: a critical review of current evidence.","authors":"Lucie d'Udekem d'Acoz, Florencia Carbone, Chamara Basnayake, Jessica Biesiekierski","doi":"10.1017/S0029665125101766","DOIUrl":"10.1017/S0029665125101766","url":null,"abstract":"<p><p>This review examines the relationship between diet and functional dyspepsia (FD), a prevalent disorder of gut-brain interaction affecting 8% of the global population and characterised by postprandial fullness, early satiety and epigastric pain or burning. Despite 40-70% of FD patients reporting symptom onset within minutes of eating, standardised dietary recommendations remain limited. The pathophysiological mechanisms underlying food-related symptoms in FD involve complex interactions between altered gastric accommodation and emptying, visceral hypersensitivity, duodenal immune activation and small intestinal microbial dysbiosis. Current evidence most strongly supports dietary lipids as potent triggers of dyspeptic symptoms, likely mediated through cholecystokinin pathways and heightened visceral sensitivity. Additionally, emerging research indicates potential benefits of fermentable carbohydrate restriction, with the low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet showing promise particularly for patients with postprandial distress syndrome. Other dietary factors such as alcohol, coffee, food chemicals, bioactive compounds and meal patterns may also influence FD symptoms though current evidence remains insufficient to inform clinical practice. While existing evidence provides a foundation for understanding diet-symptom relationships in FD, significant gaps remain in translating mechanistic insights into personalised dietary recommendations. Future research should focus on developing evidence-based dietary strategies tailored to FD subtypes, ensuring nutritional adequacy while addressing the complex interplay between nutrient sensing, duodenal immune activation and gut microbiota in symptom generation.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-9"},"PeriodicalIF":4.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appetite loss as a clinical marker of loss of function during ageing. 食欲减退作为衰老过程中功能丧失的临床标志。
IF 4.5 2区 医学
Proceedings of the Nutrition Society Pub Date : 2025-09-15 DOI: 10.1017/S0029665125101778
Wan-Hsuan Lu, Juan Luis Sánchez-Sánchez, Philipe de Souto Barreto
{"title":"Appetite loss as a clinical marker of loss of function during ageing.","authors":"Wan-Hsuan Lu, Juan Luis Sánchez-Sánchez, Philipe de Souto Barreto","doi":"10.1017/S0029665125101778","DOIUrl":"10.1017/S0029665125101778","url":null,"abstract":"<p><p>Recent literature has shown that appetite loss during ageing can lead to negative health outcomes in older adults, particularly malnutrition and mortality. However, its association with functional decline and the mechanisms driving this relationship are not well explored. This review summarises the current evidence regarding the potential effects of appetite loss on frailty and functional outcomes. Despite the limitations due to heterogeneous methodologies, including study designs, population characteristics and appetite assessments, most studies indicate that older adults with poor appetite tended to exhibit poor physical performance and increased functional limitations. Furthermore, the simultaneous weight loss in individuals experiencing appetite loss was associated with a higher risk of functional impairments. Finally, emerging evidence connects reduced appetite to biomarkers of ageing, including epigenetic alterations, chronic inflammation and the upregulation of GDF-15. Therefore, loss of appetite is a potential earlier marker of loss of function that deserves further investigation. Adopting a geroscience perspective may enhance our understanding of appetite loss during ageing and foster the development of effective interventions.</p>","PeriodicalId":20751,"journal":{"name":"Proceedings of the Nutrition Society","volume":" ","pages":"1-10"},"PeriodicalIF":4.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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