Quality of Life Research最新文献

{"title":"Correction: Translation, cultural adaptation, and validation of the Chinese standardized outcomes in nephrology-hemodialysis fatigue (C-SONG-HD fatigue) scale: a study of Chinese patients undergoing hemodialysis.","authors":"Lan-Ting Huang, Xiao-Yan Zheng, Zhi-Hong Zhang, Hong-Yan Zheng, Xin Wei, Ji-Yan Yang, Li-Hua Zhang, Xiu-Qin Lu, Ying-Qing Yang, Jin-Xia Lin, Chun-Mei Zhang, Li-Ping Luo, Dong-Hua Jiang, Shao-Hua Huang, Xiu-Bi Huang, Yue-Mei Zhan, Wen-Zhu Xu, Wei Han, Fu-Yuan Hong","doi":"10.1007/s11136-024-03889-5","DOIUrl":"10.1007/s11136-024-03889-5","url":null,"abstract":"","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1515-1516"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response shift results of quantitative research using patient-reported outcome measures: a meta-regression analysis.","authors":"Richard Sawatzky, Mathilde G E Verdam, Yseulys Dubuy, Tolulope T Sajobi, Lara Russell, Oluwagbohunmi A Awosoga, Ayoola Ademola, Jan R Böhnke, Oluwaseyi Lawal, Anita Brobbey, Amélie Anota, Lisa M Lix, Mirjam A G Sprangers, Véronique Sébille","doi":"10.1007/s11136-024-03867-x","DOIUrl":"10.1007/s11136-024-03867-x","url":null,"abstract":"<p><strong>Purpose: </strong>Our objectives were to identify characteristics of response shift studies using patient-reported outcomes (PROMs) that explain variability in (1) the detection and (2) the magnitude of response shift effects.</p><p><strong>Methods: </strong>We conducted a systematic review of quantitative studies published before June 2023. First, two-level multivariable logistic regression models (effect- and sample-levels) were used to explain variability in the probability of finding a response shift effect. Second, variability in effect sizes (standardized mean differences) was investigated with 3-level meta-regression models (participant-, effect- and sample-levels). Explanatory variables identified via the purposeful selection methodology included response shift method and type, and population-, study design-, PROM- and study-quality characteristics.</p><p><strong>Results: </strong>First, logistic regression analysis of 5597 effects from 206 samples in 171 studies identified variables explaining 41.5% of the effect-level variance, while no variables explained sample-level variance. The average probability of response shift detection is 0.20 (95% CI: 0.17-0.28). Variation in detection was predominantly explained by response shift methods and type (recalibration vs. reprioritization/reconceptualization). Second, effect sizes were analyzed for 769 effects from 114 samples and 96 studies based on the then-test and structural equation modeling methods. Meta-regression analysis identified variables explaining 11.6% of the effect-level variance and 26.4% of the sample-level variance, with an average effect size of 0.30 (95% CI: 0.26-0.34).</p><p><strong>Conclusion: </strong>Response shift detection is influenced by study design and methods. Insights into the variables explaining response shift effects can be used to interpret results of other comparable studies using PROMs and inform the design of future response shift studies.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1393-1406"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal relationships across sleep, physical activity, and mental wellbeing in early-to-mid-adolescence: a developmental cascades investigation.","authors":"Jose Marquez, Margarita Panayiotou, Reihaneh Farzinnia, Qiqi Cheng, Neil Humphrey","doi":"10.1007/s11136-025-03894-2","DOIUrl":"10.1007/s11136-025-03894-2","url":null,"abstract":"<p><strong>Purpose: </strong>Sleep (SL), physical activity (PA), and wellbeing (WB) are three factors linked to positive development in adolescence. Despite theoretical support and some empirical evidence of developmental associations between these factors, few studies have rigorously investigated reciprocal associations over time separating between-person and within-person effects, and none have investigated all three in concert. Thus, it remains unclear how the interplay between SL, PA and WB unfolds across time within individuals. This study examines this question in the crucial early-to-mid-adolescence developmental transition.</p><p><strong>Method: </strong>Separating between- and within-person effects, a random-intercept cross-lagged panel model was fitted to a dataset of N = 27,949 adolescents (age 12/13 at first timepoint) from Greater Manchester, England, using a three-by-three design (three annual timepoints: T1, T2, T3; three variables: SL, PA, WB).</p><p><strong>Results: </strong>Analyses revealed gender-specific developmental cascade pathways. Specifically, we found positive reciprocal associations between SL and WB for girls (at T1→T2), whereas for boys, SL positively predicted WB (at both T1→T2 and T2→Τ3) but WB did not predict SL. We also found that WB predicted PA for boys (at T2→T3) but this finding was sensitive to model specification and yielded a smaller effect than other cross-lagged pathways.</p><p><strong>Conclusion: </strong>Our results highlight the importance of sleep as a driver of adolescent wellbeing, and the role of gender in developmental cascade processes. Study strengths, limitations, and implications are discussed.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1233-1250"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients' experiences with the routine use of a clinical feedback system prior to consultations in ostomy care: a qualitative study.","authors":"Lill Anette Juvik, John Roger Andersen, Kisten Lerum Indrebø, Anne Marie Sandvoll","doi":"10.1007/s11136-025-03916-z","DOIUrl":"10.1007/s11136-025-03916-z","url":null,"abstract":"<p><strong>Purpose: </strong>Ostomy surgery involves significant bodily changes, and the adjustment process encompasses a broad spectrum of physical and psychosocial challenges. A clinical feedback system (CFS) has been developed to collect patient-reported outcomes as part of routine outpatient follow-up, reviewed by stoma care nurses, to better address patients' needs during their adjustment process. The intervention appears promising; however, empirical evidence supporting its benefits remains limited. Thus, we explored patients' experiences with the routine use of the CFS prior to consultations in ostomy care.</p><p><strong>Methods: </strong>A qualitative design involved 27 semi-structured individual interviews with patients using CFS as part of routine care. The data were analysed using Braun and Clarke's reflexive approach to thematic analysis.</p><p><strong>Results: </strong>The overarching theme CFS-a tool with potential and multiple mechanisms of action was developed with three themes: (1) Grasping the purpose can be challenging, (2) Preparatory learning-triggering reflection and self-awareness, and (3) Means of communication and potential for being understood. Engaging with the CFS had personal utility value with many dimensions, varying in strength and significance for each patient. Even though not everyone grasped the purpose of its use, it was part of a preparatory learning process for consultations and the adjustment process itself. It triggered reflection and self-awareness and served as a means of communication with potential for follow-up.</p><p><strong>Conclusion: </strong>Although the CFS appears promising, future research should focus on identifying the most effective methods for educating patients on its use.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1473-1482"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mere-measurement effect of patient-reported outcomes: a systematic review and meta-analysis.","authors":"Preston A Long, Anouk S Huberts, Anouk Neureiter di Torrero, Lisa R Otto, Alizé A Rogge, Valentin Ritschl, Tanja A Stamm","doi":"10.1007/s11136-025-03909-y","DOIUrl":"10.1007/s11136-025-03909-y","url":null,"abstract":"<p><strong>Purpose: </strong>The mere-measurement effect is the phenomenon in which subjects exposed to measurements have their perceptions and/or behaviors on the inquired topic affected simply through the act of responding. Patient-reported outcomes (PROs) are increasingly used to assess patient perspective and quality of life in clinical trials and different health care settings. This systematic literature review aims to assess what is currently known about the mere-measurement effect of PROs.</p><p><strong>Methods: </strong>A systematic literature review and meta-analysis was conducted. We included studies that provided evidence on perceptual or behavioral changes in patients as a result of exposure to questionnaire items assessing PROs. All adult participants were included regardless of demographics. Any study design was considered eligible for inclusion. The databases MEDLINE [PubMed], CINAHL [Ebsco], Web of Science and ScienceDirect were searched.</p><p><strong>Results: </strong>The search resulted in 636 articles which led to a final extraction of nine. Overall, seven of the nine articles reported a significant main effect, i.e. presence of the mere-measurement effect. For the meta-analysis, thirteen different interventions were included. There was a one-directional, positive and significant overall risk ratio of 1.17 [CI95% 1.04;1.30].</p><p><strong>Conclusion: </strong>This systematic review found significant potential for the mere-measurement effect to shape respondents' behaviors or perceptions for the better, opening the door to the possibility of engineering PROs to serve as a subtle intervention. Future considerations and directions for research are discussed.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1211-1220"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of signs and symptoms of dry eye disease on health-related quality of life: a cross-sectional population study among older adults.","authors":"Ulla Aapola, Paula Mosallaei, Janika Nättinen, Ilona Suurkuukka, Jaakko Tuomilehto, Sirkka Keinänen-Kiukaanniemi, Jouko Saramies, Hannu Uusitalo","doi":"10.1007/s11136-025-03907-0","DOIUrl":"10.1007/s11136-025-03907-0","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the relationship between quality of life (QoL) and ocular surface health within a Finnish population-based cohort.</p><p><strong>Methods: </strong>A cross-sectional study involved 601 individuals born between the years 1933-1956. Ocular surface health and dry eye disease (DED) were clinically evaluated using several diagnostic tests. Participants completed the Ocular Surface Disease Index (OSDI), QoL assessment with the 15D and Medical Outcomes Study 36-Item Short Form Health Survey (SF-36), and the Beck's Depression Inventory (BDI-II) questionnaires. Various statistical methods were employed to explore the associations between QoL, ocular surface health, and sex disparities.</p><p><strong>Results: </strong>DED had negative impact on QoL in all participants, and especially in women. Adjusted for comorbidities, DED doubled the odds of worse health-related QoL (15D: OR = 2.31 [95% CI: 1.24-4.31, p < 0.01]) and mental health (SF-36 MCS and BDI-II: OR = 2.08 [95% CI: 1.04-4.16, p < 0.05]). Noninvasive tear break-up time (NIBUT) correlated with all QoL scores. In women, the most significant clinical signs correlating with low QoL were NIBUT (15D: r = 0.20, p = 0.002; SF-36 MCS: r = 0.18, p = 0.026), and conjunctival staining (15D: r=-0.19, p = 0.004; BDI-II: r = 0.27, p < 0.001), whereas in men, blepharitis correlated with depression score (BDI-II: r = 0.20, p = 0.036). High OSDI was associated with worse QoL in women, but not in men.</p><p><strong>Conclusion: </strong>This first population-based study assessing general QoL data with objective clinical measures of DED indicated that among elderly population, both symptoms and signs of DED independently impacted different aspects of QoL. In addition, significant sex-differences in these associations were observed and should be considered both in research settings and when assessing and treating people with DED.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1363-1376"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wellbeing and quality of life among parents of individuals with Fontan physiology.","authors":"Kate H Marshall, Yves d'Udekem, David S Winlaw, Diana Zannino, David S Celermajer, Karen Eagleson, Ajay J Iyengar, Dominica Zentner, Rachael Cordina, Gary F Sholler, Susan R Woolfenden, Nadine A Kasparian","doi":"10.1007/s11136-025-03890-6","DOIUrl":"10.1007/s11136-025-03890-6","url":null,"abstract":"<p><strong>Purpose: </strong>To examine global and health-related quality of life (QOL) among parents of individuals with Fontan physiology and determine associations with sociodemographic, parent and child-related health, psychological, and relational factors.</p><p><strong>Methods: </strong>Parents participating in the Australian and New Zealand Fontan Registry (ANZFR) QOL Study (N = 151, Parent Mean age = 47.9 ± 10.2 years, age range: 31.6-79.6 years, 66% women; child Mean age = 16.3 ± 8.8, age range: 6.9-48.7 years, 40% female) completed a series of validated measures. Health-related QOL was assessed using the PedsQL 4.0 Core Generic Scales for adults and global QOL was assessed using a visual analogue scale (0-10).</p><p><strong>Results: </strong>Most parents (81%) reported good global QOL (≥ 6), consistent with broader population trends. Nearly one-third of parents (28%) reported at-risk health-related QOL (based on total PedsQL scores) with physical functioning most affected (44%). Psychological factors, including psychological stress and sense of coherence, emerged as the strongest correlates of global and health-related QOL, explaining an additional 16 to 30% of the variance (using marginal R²). Final models explained 35 and 57% and of the variance in global and health-related QOL, respectively (marginal R²). Relational factors, including perceived social support and family functioning contributed minimally when analyzed alongside psychological variables.</p><p><strong>Conclusion: </strong>While parents of individuals with Fontan physiology report good global QOL, challenges in health-related QOL exist. We identified key psychological, sociodemographic, and health-related factors associated with parental QOL outcomes. These data may aid early identification of physical and psychosocial difficulties and guide targeted health resource allocation for this population.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1419-1431"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delineating the dyadic coping process in HIV serodiscordant male couples: a dyadic daily diary study using the common fate model.","authors":"Jianhua Hou, Rong Fu, Taiyi Jiang, Nancy Xiaonan Yu","doi":"10.1007/s11136-025-03903-4","DOIUrl":"10.1007/s11136-025-03903-4","url":null,"abstract":"<p><strong>Purpose: </strong>Although HIV is likely to be a couple-based issue among serodiscordant male couples due to cross-partner transmission, little is known about how they cope with HIV as a team. This study aimed to examine the dyadic coping process among serodiscordant couples.</p><p><strong>Methods: </strong>A dyadic daily diary study was used to answer our research questions. One hundred and forty-one Chinese HIV serodiscordant male couples completed measures of we-disease appraisal, common dyadic coping, quality of life, and relationship satisfaction for 14 consecutive days and ART adherence, attitudes toward PrEP, quality of life, and relationship satisfaction at a 2-month post-diary assessment. Computations were based on the common fate mediation model, using multilevel structural equation modeling.</p><p><strong>Results: </strong>Regarding direct effect, we-disease appraisal was associated with both partners' quality of life at the between-person level, post-diary quality of life, attitudes toward to PrEP, relationship satisfaction at both levels as well as post-diary relationship satisfaction. Common dyadic coping mediated the association between we-disease appraisal and both partners' quality of life as well as relationship satisfaction at the within-person level. However, no mediating effects were observed at the between-person level.</p><p><strong>Conclusions: </strong>Our findings highlighted the importance of the daily dyadic coping process among HIV serodiscordant couples. Future interventions should direct resources toward fostering a shared disease appraisal and training couples in common dyadic coping strategies for their daily lives.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1317-1332"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient involvement in the development of patient-reported outcome measures used following hip or knee arthroplasty: a scoping review.","authors":"Motahareh Karimijashni, Shokoofih Abbasalipour, Marie Westby, Tim Ramsay, Paul E Beaulé, Stéphane Poitras","doi":"10.1007/s11136-025-03899-x","DOIUrl":"10.1007/s11136-025-03899-x","url":null,"abstract":"<p><strong>Purpose: </strong>Involving patients in developing patient-reported outcome measures (PROMs) is essential for accurately capturing their perspectives. However, understanding how patients were involved in developing PROMs used after hip or knee arthroplasty is limited. This scoping review aimed to evaluate whether patients were involved in the development of these PROMs and how they were involved.</p><p><strong>Methods: </strong>Two independent reviewers documented patient involvement in item development and comprehensibility testing for 50 PROMs used after hip or knee arthroplasty. Trends in patient involvement over time were analyzed using binary logistic regression.</p><p><strong>Results: </strong>There was no documentation of patient involvement in a collaborative role during the PROM development processes. Regarding the consultative role, of these 26 PROMs, they contributed to item development in 13 PROMs (26%) and comprehensibility testing in four PROMs (8%) and both item development and comprehensibility testing in nine PROMs (18%). Patients who underwent arthroplasty were involved in one or both phases in ten PROMs (20%), while patients with other lower extremity conditions were involved in 16 PROMs (32%). Patients who underwent arthroplasty contributed to both phases in five PROMs: Oxford Knee Score-Activity and Participation Questionnaire, Patient's Knee Implant Performance Questionnaire, Patient-Reported Outcomes Measurement Information System R-Plus-Osteoarthritis of the Knee, Oxford Arthroplasty Early Recovery Score and Oxford Arthroplasty Early Change Score. In addition, our analysis revealed no significant change in patient involvement in a consultative role during either item development or comprehensibility evaluation over time since 1982, when the first PROM included in this review was developed (p = 0.21).</p><p><strong>Conclusions: </strong>Almost half of PROMs used after arthroplasty did not involve patients in their development, highlighting the need to address this gap in development of PROMs. There is also a need to analyze PROMs to ensure they accurately reflect the outcomes that matter to patients.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1195-1209"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-compassion, mindfulness, and emotion regulation predict multiple dimensions of quality of life in US post-9/11 veterans.","authors":"Marcus G Wild, John David Coppin, Corina Mendoza, Allison Metts, Rahel Pearson, Suzannah K Creech","doi":"10.1007/s11136-025-03908-z","DOIUrl":"10.1007/s11136-025-03908-z","url":null,"abstract":"<p><strong>Purpose: </strong>Quality of life (QoL), defined by satisfaction, capacity for activities, and functional role performance, is an outcome of interest for both medical and psychological interventions. Among US veterans, QoL is lower than the general population and is associated with mortality and suicide. Third-wave psychosocial interventions (e.g., Acceptance and Commitment Therapy) emphasize QoL as the primary outcome of interest, and specific third-wave intervention targets (e.g., self-compassion, mindfulness, emotion regulation) may contribute to the satisfaction, capacity, and functional domains of QoL of veterans. To evaluate the longitudinal associations of self-compassion, mindfulness, and emotional regulation with three domains of QoL (psychosocial satisfaction, psychosocial capacity, and psychosocial relationship functioning) in US veterans.</p><p><strong>Methods: </strong>351 US combat-deployed veterans self-reported measures of QoL, self-compassion, mindfulness, and emotional regulation at four timepoints across 24 months. Bayesian multivariate multilevel models were fit to the QoL outcomes.</p><p><strong>Results: </strong>Results indicated that all three domains of QoL remained relatively stable over the course of the study period. Increased psychosocial satisfaction and psychosocial capacity were both associated with increased mindfulness and emotion regulation, whereas self-compassion was only related to greater psychosocial capacity for male veterans. Increased functional role performances in romantic and family relationships were associated with increased emotion regulation, with romantic relationship functioning also being associated with increased mindfulness and family relationship functioning with increased self-compassion.</p><p><strong>Conclusion: </strong>These results suggest that mechanisms of third-wave interventions have an impact on QoL among US veterans and that veteran QoL may be improved by broader integration of mindfulness and emotion regulation-based interventions.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"1433-1442"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143067511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}