Quality of Life Research最新文献

{"title":"Long-COVID symptom burden and the experience of adversity: the importance of response-shift effects over 3 years of the pandemic.","authors":"Carolyn E Schwartz, Katrina Borowiec, Bruce D Rapkin","doi":"10.1007/s11136-025-03962-7","DOIUrl":"10.1007/s11136-025-03962-7","url":null,"abstract":"<p><strong>Background/objectives: </strong>Long COVID is a long-term legacy of the global pandemic. This study aimed to illuminate how Long COVID impacts individuals, and how response-shift effects influence Long COVID's impact. Methodologically, it expands the application of longitudinal statistical methods to test a more dynamic investigation of psychosocial factors in health over time.</p><p><strong>Methods: </strong>This quasi-experimental longitudinal cohort study collected data up to four times over 3 years of the COVID pandemic (May 2020 to April 2023). This study focused on 1151 participants divided into four Long-COVID Symptom Burden groups (Never Had COVID; Low, Medium, and High Long-COVID Symptom Burden). It examined COVID-specific outcomes: General Hardship, Healthcare Hardship, Worry, and Social Support. The Quality of Life Appraisal Profile_v2-Short Form assessed cognitive-appraisal processes. Direct and moderated response-shift effects were tested using longitudinal mixed models that examined main effects and interactions of individuals' changes in cognitive-appraisal processes from their usual, over time, and by group over time, after adjusting for sociodemographic covariates and individual's usual appraisal processes, and considering the impact of multiple comparisons.</p><p><strong>Results: </strong>Notable response-shift effects were revealed on all four COVID-specific outcomes, reflecting both direct and moderated response-shift effects. The experience of COVID-specific adversity was related to various appraisal processes but the nature of the relationship often varied by Long-COVID symptom burden. The appraisal processes that were most salient included patterns of emphasis related to getting used to and handling demands or recent changes, problem-solving goals, and comparing oneself to similar others. Individuals in the high Long-COVID Symptom-Burden Group were particularly highlighted in response-shift effects. The broad conclusions of both raw and multiplicity-adjusted results were similar. That is, there were notable reprioritization and reconceptualization response-shift effects for all outcomes, and notable but fewer recalibration response-shift effects.</p><p><strong>Conclusions: </strong>Response-shift effects, measured via the direct assessment of cognitive-appraisal processes, were prominent in dealing with the COVID pandemic. The present study documented that COVID-specific adversity can be attenuated or exacerbated depending on individuals' patterns of emphasis, goals, and standards of comparison. The study's utilization of data collected at four time points over 3 years of the global pandemic provided a more comprehensive and far-reaching evaluation of response shift than earlier work. The theory-driven analytic methodology developed in the present work facilitated a more nuanced description of direct and moderated response-shift effects.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"2233-2257"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life and access to treatment for patients with multiple sclerosis during economic crisis: the Lebanese experience.","authors":"Maya Zeineddine, Ghida Ismail, Malak Issa, Taghrid El-Hajj, Hassan Tfaily, Mohamad Dassouki, Elie Assaf, Halim Abboud, Pascale Salameh, Amal Al-Hajje, Farid Boumediene, Bassem Yamout","doi":"10.1007/s11136-025-03970-7","DOIUrl":"10.1007/s11136-025-03970-7","url":null,"abstract":"<p><strong>Purpose: </strong>Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that can lead to lifelong disability, significantly impacting patient's quality of life (QOL). The current Lebanese economic crisis led to limited accessibility to MS therapies and had a major impact on QOL.The aim of this study was to assess QOL in a cohort of Lebanese MS patients, and its association with socio-demographic factors, disease characteristics, and treatment accessibility.</p><p><strong>Methods: </strong>A cross-sectional, survey-based study was conducted between June and September 2022 in Lebanese patients with confirmed MS diagnosis as per the 2017 McDonald criteria. Structured questionnaires were used to obtain (1) socio-demographic and medical information, (2) QOL assessment using the MS International QOL questionnaire (MusiQoL), and (3) information related to barriers in accessing MS therapies. All questionnaires were administered via telephone call.</p><p><strong>Results: </strong>A total of 350 MS patients were included in the study. Most participants (92.3%) were diagnosed with relapsing-remitting MS and were females (65.1%) with a mean age of 39.4 ± 11.4 years. The mean MusiQol global index was 69.2 ± 11.5. In the multivariate analysis, younger age, higher level of education, being employed, being married, living outside the capital Beirut, and having no physical disability were significantly associated with higher MusiQol global index scores. A total of 216 Lebanese MS patients (61.7%) had no access to MS treatments due to the economic crisis. Treatment discontinuation and lack of governmental or private insurance were significant predictors of lower MusiQol scores.</p><p><strong>Conclusion: </strong>The economic crisis and resultant recession in Lebanon had a significantly negative impacted on QOL and treatment accessibility of MS patients. Socio-demographic factors, disease characteristics and treatment accessibility were strong predictors of QOL.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"2293-2303"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The comprehensibility and feasibility of the modified brief pain inventory and fear of pain questionnaire adapted for children and young people with cerebral palsy.","authors":"Meredith Grace Smith, Rachel J Gibson, Mathew Schibani, Remo N Russo, Abirami Thirumanickam, Adrienne R Harvey","doi":"10.1007/s11136-025-03981-4","DOIUrl":"10.1007/s11136-025-03981-4","url":null,"abstract":"<p><strong>Purpose: </strong>To test the comprehensibility and feasibility of the modified brief pain inventory (mBPI) and Fear of Pain Questionnaire for Children short-form (FOPQ-C-SF) adapted for children and young people with cerebral palsy (CP), with diverse cognitive and communication abilities. Improving assessment of pain interference (mBPI) and pain-related fear (FOPQ-C-SF) in CP can enhance quality of life by increasing access to under-utilised interventions targeting pain-related physical disability and mental health.</p><p><strong>Methods: </strong>A convergent mixed methods approach was used. Twenty-two people (5-30 years) with CP completed the adapted mBPI and FOPQ-C-SF in a cognitive interview, administered by pen/paper or TalkingMats^®, an evidence-based visual communication framework. Cognitive interviewing approaches were adapted to optimise participation and expression for diverse cognitive and communication abilities. Quantitative data were analysed to report tool administration times, overall completion rates and communication effectiveness. Qualitative data were analysed by content analysis to determine further changes required to the tools.</p><p><strong>Results: </strong>Median administration times were 6.2 min (IQR = 5.3-7.6) for mBPI and 4.1 min (IQR = 2.7-4.9) for FOPQ-C-SF. All completed the mBPI. Three did not complete the FOPQ-C-SF due to fatigue, challenging behaviour and parent recommendation. Ten minor changes were identified.</p><p><strong>Conclusion: </strong>The adapted mBPI and FOPQ-C-SF are likely comprehensible and feasible for children and young people with CP, including those with diverse cognitive and communication abilities. It is likely most children and young people with CP can effectively communicate responses to both tools. The adapted tools will now undergo further psychometric testing, prior to becoming freely available for clinical and research use.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"2377-2392"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of early-life food deprivation on health-related quality of life among older people in China: evidence from CHARLS.","authors":"Jingwen Liu, Wenfeng Lu, Yue Wang, Yaqi Wang, Xueying Xu, Yuan He, Qingyun Lv, Hairong Chang, Yue Zhao, Xiaonan Zhang, Xiaoying Zang, Na Wei","doi":"10.1007/s11136-025-03978-z","DOIUrl":"10.1007/s11136-025-03978-z","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to explore the impact of early-life food deprivation on health-related quality of life (HRQoL) among older people, providing a scientific basis for developing public health strategies to improve the quality of life for older people.</p><p><strong>Methods: </strong>Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS), focusing on participants aged ≥60 years. The study included 7,192 eligible participants, categorized based on their self-reported early-life food deprivation experiences. HRQoL was measured using a newly developed scale based on variables from the Short Form-36 (SF-36) scale and CHARLS questionnaires. Inverse probability of treatment weighting (IPTW) was used to control for baseline differences. Weighted linear regression models were employed to analyze the impact of early-life food deprivation levels on HRQoL.</p><p><strong>Results: </strong>Findings indicate that older people who experienced early-life food deprivation exhibit a lower HRQoL (β = -1.83; 95% CI: -2.59, -1.07). This effect is particularly pronounced in older people with extreme early-life food deprivation (β = -3.50; 95% CI: -4.53, -2.47). Specifically, they exhibited lower scores in physical functioning, bodily pain, general health, role emotional, vitality, and mental health.</p><p><strong>Conclusions: </strong>Early-life food deprivation has a lasting negative effect on the HRQoL among older people. The results highlight the importance of early identification and improvement in cases of early-life food deprivation, alongside the implementation of targeted interventions. These measures can help improve the HRQoL of older adults affected by early-life food deprivation.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"2305-2316"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurocognitive impairment and patient-proxy agreement on health-related quality of life evaluations in recurrent high-grade glioma patients.","authors":"Ivan Caramanna, Martin Klein, Martin van den Bent, Ahmed Idbaih, Martin J B Taphoorn, Linda Dirven, Thierry Gorlia, Jaap C Reijneveld","doi":"10.1007/s11136-025-03984-1","DOIUrl":"10.1007/s11136-025-03984-1","url":null,"abstract":"<p><strong>Purpose: </strong>The rate of missing data on patient-reported health-related quality of life (HRQOL) in brain tumor clinical trials is particularly high over time. One solution to this issue is the use of proxy (i.e. partner, relative, informal caregiver) ratings in lieu of patient-reported outcomes (PROs). In this study, we investigated patient-proxy agreement on HRQOL outcomes in high-grade glioma (HGG) patients.</p><p><strong>Methods: </strong>Generic and disease-specific HRQOL was assessed using the EORTC QLQ-C30 and QLQ-BN20 in a sample of 500 patient-proxy dyads participating in EORTC trials 26101 and 26091. Patients were classified as impaired or intact based on their neurocognitive performance. The level of patient-proxy agreement was measured using Lin's concordance correlation coefficient (CCC), and the Bland-Altman limit of agreement. The Wilcoxon signed-rank test was used to evaluate differences between patients' and proxies' HRQOL.</p><p><strong>Results: </strong>Patient-proxy agreement in all HGG patients (N = 500) ranged from 0.399 to 0.743. Only 18.8% of all patients were neurocognitively intact. Lin's CCC ranged from 0.231 to 0.811 in cognitively impaired patients and their proxies, and from 0.376 to 0.732 in cognitively intact patients and their proxies.</p><p><strong>Conclusions: </strong>The results of this study suggest that the moderate level of patient-proxy agreement observed in HGG patients would allow reliance on proxies' reports. However, the differences observed between neurocognitively impaired and intact patients stress the importance of taking into consideration patient's clinical and neurocognitive status as well as their mental capacity for adequate clinical decision making in general and for PRO-related issues.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":"2405-2418"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High societal costs and reduced health-related quality of life in inflammatory and systemic immune disease-associated dilated cardiomyopathies.","authors":"Maurits Sikking, Isabell Wiethoff, Michiel Henkens, Silvia Evers, Sophie Stroeks, Max Venner, Jerremy Weerts, Hans-Peter Brunner-la Rocca, Christian Knackstedt, Vanessa van Empel, Michelle Michels, Stephane Heymans, Mickaël Hiligsmann, Job Verdonschot","doi":"10.1007/s11136-025-04027-5","DOIUrl":"https://doi.org/10.1007/s11136-025-04027-5","url":null,"abstract":"","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing presentation formats for SF-6Dv2 health status valuation: a qualitative study using cognitive interviews.","authors":"Jahyun Cho, Eun-Young Bae, Min-Woo Jo, Minsu Ock","doi":"10.1007/s11136-025-04036-4","DOIUrl":"https://doi.org/10.1007/s11136-025-04036-4","url":null,"abstract":"<p><strong>Purpose: </strong>The SF-6Dv2 health status valuation using the discrete choice experiment (DCE) method requires effective presentation strategies to improve respondents' overall understanding and reduce bias, particularly in online surveys. This study aimed to determine the optimal presentation formats for DCE choice tasks through qualitative interviews.</p><p><strong>Methods: </strong>We conducted cognitive interviews with 40 South Korean adults using the think-aloud and retrospective probing methods. Participants evaluated five presentation formats (non-emphasized, bold-underlined, yellow-highlighted, graphic circle, and color-shaded) and two duration attribute placement options (upfront vs. end).</p><p><strong>Results: </strong>Findings revealed that the presentation format influenced three key areas: readability, comprehension, and comparative judgment. The yellow-highlighted format was the most preferred (50%), followed by the bold-underlined (37.5%) and graphic circle formats (25%), with multiple responses allowed. However, the yellow-highlighted format was criticized for being a visual burden and overlooking non-highlighted information, while the graphic format had issues such as scale direction confusion and inappropriate level summation across attributes. Meanwhile, the bold-underlined format was described easy to read, helpful in grasping the meaning quickly, and visually balanced, thereby reducing visual overload. Moreover, it supported comparative judgment by allowing users to clearly distinguish and compare domains without cognitive fatigue. Regarding duration placement, 26 participants preferred upfront placement, stating that it provided essential context for evaluation. Interestingly, the participants preferring upfront placement prioritized survival duration, while those preferring end placement emphasized the quality of life.</p><p><strong>Conclusion: </strong>While the yellow-highlighted, bold-underlined, and graphic formats improved comprehension, we recommend the bold-underlined format for future SF-6Dv2 valuation studies as it balances comprehension enhancement with greater stability in choice contexts. The findings also suggest that the presentation format has the potential to influence DCE response patterns, warranting further consideration in survey design.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144744536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does context matter? A discrete choice experiment investigating the impact of palliative context on EQ-5D-5L health state valuation.","authors":"Irina Kinchin, Peiwen Jiang, Deborah Street, Richard Norman, David Currow, Meera Agar, Charles Normand, Bridget Johnston, Peter May, Rosalie Viney, Brendan Mulhern","doi":"10.1007/s11136-025-04023-9","DOIUrl":"https://doi.org/10.1007/s11136-025-04023-9","url":null,"abstract":"<p><strong>Purpose: </strong>Ensuring the values applied in health technology assessment of palliative care accurately reflect the palliative context is crucial for informed and effective resource allocation. The aim of this study is to examine whether the valuation of EQ-5D health states varies when framed within a palliative care needs context: limited life expectancy and availability of supports.</p><p><strong>Methods: </strong>This study was a multinational cross-sectional discrete choice experiment (DCE) with respondents from the general populations of Australia (n = 2,082), Ireland (n = 1,280), and the UK (n = 2,009). Each participant was presented with a series of 20 choice sets, in which they were asked to choose between two EQ-5D-5L health states and immediate death. Half of the choice sets were accompanied by a \"context vignette\" while the remaining half were \"context-free\". The context vignettes, developed through a four-stage iterative process, described four distinct levels of palliative care needs. A D-efficient DCE design was developed, and the data were analysed using multinomial logit regression models.</p><p><strong>Results: </strong>The study found inconsistencies in the EQ-5D-5L health state valuations in palliative contexts compared with context free valuation. Both life expectancy and level of support impacted health state valuation, with life expectancy having the larger effect. The inclusion of the palliative care vignettes substantially increased the number of health states that were given values worse than dead. This increase was more pronounced in Australia and the UK than in Ireland.</p><p><strong>Conclusion: </strong>These results imply that EQ-5D value sets that are context free require careful interpretation, especially when applied in settings such as palliative care.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel CAT method for QoL screening: proof-of-principle study with comparisons to standard methods.","authors":"Anastasios Psychogyiopoulos, Niels Smits, L Andries van der Ark","doi":"10.1007/s11136-025-04035-5","DOIUrl":"https://doi.org/10.1007/s11136-025-04035-5","url":null,"abstract":"<p><strong>Purpose: </strong>This proof-of-principle study investigated a novel Computer Adaptive Testing (CAT) method termed Latent-class and Sum score based Computerized Adaptive Testing (LSCAT), developed for screening purposes. LSCAT was assessed for its ability to accurately predict depression symptoms during health-related quality of life (HR-QoL) screenings.</p><p><strong>Methods: </strong>LSCAT's performance was compared with two benchmark CAT methods, Stochastic Curtailment (SC) and Decision Tree based Computer Adaptive Testing (DTCAT), using data from the Patient Health Questionnaire-9 (PHQ-9).</p><p><strong>Results: </strong>LSCAT consistently outperformed both SC and DTCAT in terms of predictive accuracy, achieving the lowest rates of Type I error. Furthermore, LSCAT's Type II error rates were at least as low as those of SC and significantly lower than those of DTCAT across all simulation scenarios.</p><p><strong>Conclusion: </strong>These results suggest that LSCAT is a promising method for developing valid and efficient screening tools in HR-QoL research and practice.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Putting CATs and item banks to work: How to construct predictive and sensitive PROMIS screeners for use in ambulatory oncology.","authors":"Benjamin D Schalet, Michael A Kallen, Laura M Perry, Sofia F Garcia, David Cella","doi":"10.1007/s11136-025-04015-9","DOIUrl":"10.1007/s11136-025-04015-9","url":null,"abstract":"<p><strong>Purpose: </strong>Incorporating PROMs into routine clinical care comes with numerous challenges, including pressure to move patients through office visits with brief, efficient assessments. The purpose of our study was to select and evaluate very short PROMIS screeners with full-bank simulations and predictive accuracy analysis.</p><p><strong>Methods: </strong>We identified candidate pairs of items for PROMIS Anxiety, Depression, Pain Interference, Fatigue, and Physical Function, on the basis of frequently selected CAT items at both normal and clinical thresholds. We then simulated full-bank responses for 10,000 patients with a T-score mean of 50 in Fatigue, Depression, Pain Interference, and Anxiety, but 45 for Physical Function. We scored candidate 2-item short-form pairs, but also evaluated a 1-item screener and a 4-item fixed CAT for comparison purposes. Clinical thresholds were set at 1 SD in the direction of worse health; diagnostic values were computed based on agreement with full-bank T-scores. We aimed for sensitivity and positive predictive values (PPV) above 0.80, considering also diversity and redundancy of content.</p><p><strong>Results: </strong>Average sensitivity of our chosen 2-item pairs across the five domains was 0.84 (range 0.80-0.89), while the average PPV was 0.82 (0.80-0.85). While the 1-item screeners for Anxiety and Depression performed poorly, they met or approached our criteria for Pain Interference, Fatigue and Physical Function.</p><p><strong>Conclusion: </strong>Five 2-item customized PROMIS forms are available for use in routine clinical care, such as distress screening in oncology. Our study provides a useful complement to psychometric criteria, helping to minimize misclassification of patients in need during screening.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}