Przegla̜d Gastroenterologiczny最新文献

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Undifferentiated pleiotropic spermatic duct sarcoma: a surgical surprise in the inguinal canal that calls for attention. 未分化多性精管肉瘤:腹股沟管的手术意外,需要引起注意。
IF 1.7
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-11-26 DOI: 10.5114/pg.2024.145362
Georgios Tsakaldimis, Georgios-Ioannis Verras, Michail Pitiakoudis, Christos Kalaitzis, Anastasios Karayiannakis, George Pappas-Gogos, Levan Tchabashvili, Konstantinos Tasios, Angelis Peteinaris, Vasileios Tatanis, Francesk Mulita
{"title":"Undifferentiated pleiotropic spermatic duct sarcoma: a surgical surprise in the inguinal canal that calls for attention.","authors":"Georgios Tsakaldimis, Georgios-Ioannis Verras, Michail Pitiakoudis, Christos Kalaitzis, Anastasios Karayiannakis, George Pappas-Gogos, Levan Tchabashvili, Konstantinos Tasios, Angelis Peteinaris, Vasileios Tatanis, Francesk Mulita","doi":"10.5114/pg.2024.145362","DOIUrl":"10.5114/pg.2024.145362","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"16 4","pages":"456-459"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forgettable in the care of liver cirrhosis: the unseen culprits of progression from bad to worse. 肝硬化护理中的 "遗忘":病情恶化的隐形罪魁祸首。
IF 1.3
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-03-14 DOI: 10.5114/pg.2024.136361
Maha Elsabaawy, Omkosoum Alhaddad
{"title":"Forgettable in the care of liver cirrhosis: the unseen culprits of progression from bad to worse.","authors":"Maha Elsabaawy, Omkosoum Alhaddad","doi":"10.5114/pg.2024.136361","DOIUrl":"https://doi.org/10.5114/pg.2024.136361","url":null,"abstract":"<p><p>Patients with liver cirrhosis constitute a critically ill and unique population, and their stability relies on a well-coordinated multidisciplinary team with a carefully structured plan. Overlooking any aspect of this plan can expedite disease progression, leading to severe complications. The lack of disease-specific nutritional guidance, the prevalent sedentary lifestyle among patients, and insufficient screening for hepatocellular carcinoma, oesophageal varices, sarcopaenia, minimal hepatic encephalopathy, and diabetes mellitus, along with fibrosis progression and cirrhosis decompensation, can add further complexities. Additionally, devaluing the impact of obesity in triggering liver cirrhosis can be disadvantageous. Prolonged and inappropriate use of proton pump inhibitors also poses a significant challenge with a wide range of complications. These often-unheeded aspects in the care of liver cirrhosis patients represents the unseen culprits of progression from bad to worse and warrant serious consideration.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 1","pages":"6-17"},"PeriodicalIF":1.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10985753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stent insertion for malignant hilar obstruction: a meta-analysis of percutaneous versus endoscopic approaches. 恶性肺门梗阻的支架置入:经皮与内镜入路的meta分析。
IF 1.7
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2023-07-27 DOI: 10.5114/pg.2023.130124
Gang Wang, Yu-Fei Fu, Yan-Jin Yu
{"title":"Stent insertion for malignant hilar obstruction: a meta-analysis of percutaneous versus endoscopic approaches.","authors":"Gang Wang, Yu-Fei Fu, Yan-Jin Yu","doi":"10.5114/pg.2023.130124","DOIUrl":"10.5114/pg.2023.130124","url":null,"abstract":"<p><strong>Introduction: </strong>In an effort to treat patients with malignant hilar obstruction (MHO), both percutaneous trans-hepatic biliary stenting (PTBS) and endoscopic biliary stenting (EBS) strategies have been implemented in the clinic, but the relative advantages of these techniques remain to be clarified.</p><p><strong>Aim: </strong>This meta-analysis was designed to compare the relative clinical efficacy of PTBS and EBS in MHO patients.Material and methods: Relevant studies were identified through searches of the PubMed, Web of science, and Wanfang databases, and pooled analyses of these studies were then performed.</p><p><strong>Results: </strong>In total, this meta-analysis included 11 studies enrolling 530 and 645 patients who underwent PTBS and EBS, respectively. Pooled rates of technical success in the PTBS patients were significantly higher than those for EBS patients (<i>p</i> < 0.0001). PTBS patients also exhibited significantly lower pooled cholangitis (<i>p</i> = 0.03) and pancreatitis (<i>p</i> < 0.0001) rates as compared to individuals in the EBS group. However, there were no significant differences in pooled clinical success rates (<i>p</i> = 0.45), haemorrhage rates (<i>p</i> = 0.57), stent patency (<i>p</i> = 0.96), or overall survival (<i>p</i> = 0.73) when comparing these groups. In a subgroup analysis, PTBS was not found to be superior to EBS as a treatment for Bismuth type III/IV MHO patients. However, PTBS did exhibit superior technical success and complication rates relative to EBS when treating hilar cholangiocarcinoma patients.</p><p><strong>Conclusions: </strong>PTBS is superior to EBS with respect to many technical success and safety criteria when employed for the management of MHO patients.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 3","pages":"255-262"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare case of synchronous management of gastroesophageal junction adenocarcinoma and renal cell carcinoma: is it just another oesophagectomy? 一例罕见的胃食管交界处腺癌和肾细胞癌同步治疗病例:这只是另一种食管切除术吗?
IF 1.7
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-09-12 DOI: 10.5114/pg.2024.143046
Natasha Hasemaki, Michail Vailas, Chrysovalantis Vergadis, Maria Sotiropoulou, Ioannis Anastasiou, Helen Sarlanis, Michalis V Karamouzis, Francesk Mulita, Theodore Liakakos, Dimitrios Schizas
{"title":"A rare case of synchronous management of gastroesophageal junction adenocarcinoma and renal cell carcinoma: is it just another oesophagectomy?","authors":"Natasha Hasemaki, Michail Vailas, Chrysovalantis Vergadis, Maria Sotiropoulou, Ioannis Anastasiou, Helen Sarlanis, Michalis V Karamouzis, Francesk Mulita, Theodore Liakakos, Dimitrios Schizas","doi":"10.5114/pg.2024.143046","DOIUrl":"10.5114/pg.2024.143046","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 3","pages":"337-343"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized controlled effect of treadmill walking exercise on liver enzymes, psychological burden, and erectile dysfunction in men with hepatitis C. 跑步机步行运动对丙型肝炎患者肝酶、心理负担和勃起功能障碍的随机对照影响
IF 1.7
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2023-08-07 DOI: 10.5114/pg.2023.130334
Ali Mohamed Ali Ismail, Nadia Saad Sayed Ahmed El Gressy, Mona Darwish Hegazy, Ahmed Mohamed Abdel-Halim Elfahl, Omnia Saeed Mahmoud Ahmed
{"title":"Randomized controlled effect of treadmill walking exercise on liver enzymes, psychological burden, and erectile dysfunction in men with hepatitis C.","authors":"Ali Mohamed Ali Ismail, Nadia Saad Sayed Ahmed El Gressy, Mona Darwish Hegazy, Ahmed Mohamed Abdel-Halim Elfahl, Omnia Saeed Mahmoud Ahmed","doi":"10.5114/pg.2023.130334","DOIUrl":"10.5114/pg.2023.130334","url":null,"abstract":"<p><strong>Introduction: </strong>Exercise is a simple, safe, and affordable solution that can be easily taught to men with chronic illnesses to improve their psychological burden and sexual health.</p><p><strong>Aim: </strong>Since the role of exercise in ameliorating the psychological burden associated with erectile dysfunction (ED) in hepatitis C (HC) men was not explored, this research aimed to explore this role.</p><p><strong>Material and methods: </strong>This HC study was a randomized-controlled exercise-rehabilitation trial. Recruitment of HC men with ED was conducted from El-Sahel Teaching Hospital, Cairo, Egypt. Men (<i>n</i> = 46) were randomly assigned to a 12-week walking-exercise group (WEG, <i>n</i> = 23 HC men with ED received a 1-hour treadmill walking 3 times weekly) or a control group (<i>n</i> = 23 HC men with ED, who did not change their daily physical activity during the research period). Besides Beck's Depression Inventory (BDI), Arabic Version of the Five-Item Version International Index of Erectile Function (IIEF-5), Profile of Mood States Questionnaire (POMSQ), and Ten-Statement Rosenberg self-esteem scale (TSRSE), HC participants' liver enzymes, alanine transaminase (ALT), and aspartate transaminase (AST) were assessed.</p><p><strong>Results: </strong>Significant improvements of POMSQ, BDI, AST, IIEF-5, ALT, and TSRSE within the WEG only were seen. No significant changes occurred in the control group's parameters.</p><p><strong>Conclusions: </strong>Exercise (walking) is a good modality to improve liver enzymes, ED, and ED-associated psychological burden (depression, low self-esteem, and mood disturbances) in HC men with ED.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"1 1","pages":"263-270"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of oxidative stress, metabolic disorders in colorectal cancer patients. 结直肠癌患者氧化应激与代谢紊乱的关系
IF 1.7
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-05-28 DOI: 10.5114/pg.2024.139995
Konrad Zaręba, Justyna Dorf, Kerianne Cummings, Seena Tabibi, Mateusz Maciejczyk, Bogusław Kędra
{"title":"Associations of oxidative stress, metabolic disorders in colorectal cancer patients.","authors":"Konrad Zaręba, Justyna Dorf, Kerianne Cummings, Seena Tabibi, Mateusz Maciejczyk, Bogusław Kędra","doi":"10.5114/pg.2024.139995","DOIUrl":"https://doi.org/10.5114/pg.2024.139995","url":null,"abstract":"<p><strong>Introduction: </strong>Colorectal cancer have been one of the most common malignant neoplasm in the world. In most patients with this cancer, we can observe both redox homeostasis and nutritional disorders.</p><p><strong>Aim: </strong>To assess the occurrence of oxidative stress in patients with colorectal cancer and its severity depending on the nutritional status of patients.</p><p><strong>Material and methods: </strong>The study group consisted of 50 patients with colorectal cancer. In the control group, samples were obtained from 40 healthy subjects. Basal metabolic index and nutrition risk screening (NRS) 2002 scale was completed. The total antioxidant capacity (TAC), total oxidant status (TOS), malondialdehyde (MDA) were determined yielding the oxidative stress index (OSI) determined by the TOS/TAC ratio and TAC/MDA ratio.</p><p><strong>Results: </strong>There were statistically significant differences (<i>p</i> < 0.05) in the levels of not only TAC, TOS, OSI, but also MDA and TAC/MDA. In healthy patients, the TAC and TAC/MDA level was significantly higher (<i>p</i> < 0.05) compared to the cancer patients, while the TOS, OSI and MDA level was significantly lower (<i>p</i> < 0.05). In patients with BMI < 24.9 kg/m<sup>2</sup>, the level of TAC was significantly higher and the level of TOS was significantly lower (<i>p</i> < 0.05) compared to patients with BMI > 24.9 kg/m<sup>2</sup>. In patients with features of malnutrition according to the NRS 2002 scale, TOS and OSI were statistically significantly higher (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Neoplastic disease, such as colorectal cancer, precipitates an increase in oxidative stress. Concurrently, the nutritional status of patients, especially malnutrition, further intensifies this process.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 2","pages":"206-213"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clostridioides difficile infection: a changing treatment paradigm. 艰难梭菌感染:不断变化的治疗模式。
IF 1.3
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-03-11 DOI: 10.5114/pg.2024.136237
Yousif Al Naser, Marriam AlGashami, Layth Aljashaami
{"title":"<i>Clostridioides difficile</i> infection: a changing treatment paradigm.","authors":"Yousif Al Naser, Marriam AlGashami, Layth Aljashaami","doi":"10.5114/pg.2024.136237","DOIUrl":"https://doi.org/10.5114/pg.2024.136237","url":null,"abstract":"<p><p><i>Clostridioides difficile</i> infection (CDI) poses a persistent challenge in healthcare, with substantial morbidity and mortality implications. This comprehensive review explores current CDI management, emphasising guidelines from IDSA, SHEA, and ESCMID. Additionally, this study spotlights recent drug developments that have the potential to reshape CDI treatment paradigms. Within the current treatment landscape, fidaxomicin, vancomycin, bezlotoxumab, and faecal microbiota transplantation offer varied options, each with its unique strengths and limitations. Fidaxomicin, effective yet resource-constrained, presents a dilemma, with vancomycin emerging as a pragmatic alternative. Bezlotoxumab, though augmenting antibiotics, grapples with cost and safety concerns. Meanwhile, faecal microbiota transplantation, highly efficacious, confronts evolving safety considerations. The horizon of CDI treatment also features promising therapies such as SER-109 and Rebyota, epitomising the evolving paradigm. As CDI management advances, the critical role of standardised microbiome restoration therapies becomes evident, ensuring long-term safety and diversifying treatment strategies.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 1","pages":"1-5"},"PeriodicalIF":1.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10985755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiota modifications in prehabilitation - the next step towards comprehensive preparation for surgery. The scoping review. 康复过程中微生物群的改变——迈向全面手术准备的下一步。范围审查。
IF 1.7
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-12-11 DOI: 10.5114/pg.2024.145833
Igor Łoniewski, Tomasz Banasiewicz, Jerzy Sieńko, Karolina Skonieczna-Zydecka, Ewa Stachowska
{"title":"Microbiota modifications in prehabilitation - the next step towards comprehensive preparation for surgery. The scoping review.","authors":"Igor Łoniewski, Tomasz Banasiewicz, Jerzy Sieńko, Karolina Skonieczna-Zydecka, Ewa Stachowska","doi":"10.5114/pg.2024.145833","DOIUrl":"10.5114/pg.2024.145833","url":null,"abstract":"<p><p>This scoping review highlights the role of microbiota modifications in prehabilitation for surgical patients. It emphasises the importance of optimising gut microbiota through probiotics, synbiotics, and postbiotics to reduce surgical complications, such as surgical site infections (SSIs). The review highlights that gut dysbiosis, worsened by surgery, stress, antibiotics, and poor diet, can lead to increased infection risk and slower recovery. Evidence from systematic reviews, meta-analyses, and randomised controlled trials suggests that microbiota-targeted interventions can reduce SSIs, enhance immune responses, and promote quicker recovery. The review advocates for an individualised approach to prehabilitation, incorporating microbiota modifications based on patient-specific factors and surgery type. However, it also notes the need for further research to standardise therapeutic regimens and confirm the safety and efficacy of these interventions in clinical practice.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"16 4","pages":"347-361"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis. 食物过敏原和口服免疫治疗作为嗜酸性食管炎的指标。
IF 1.7
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-05-13 DOI: 10.5114/pg.2024.139534
Andrzej Kuźmiński, Justyna Przybyszewska, Zbigniew Bartuzi
{"title":"Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis.","authors":"Andrzej Kuźmiński, Justyna Przybyszewska, Zbigniew Bartuzi","doi":"10.5114/pg.2024.139534","DOIUrl":"10.5114/pg.2024.139534","url":null,"abstract":"<p><p>Eosinophilic esophagitis (EoE) is a chronic immune-mediated esophageal disease, clinically characterised by symptoms of esophageal dysfunction and histologically by eosinophilic infiltration of its wall. The last 3 decades have seen a sharp increase in its incidence to the point that it is called the second most common esophageal disease after reflux disease in some recent studies. The main indicators of EoE are food allergens and in recent years the extremely important role of oral immunotherapy (OIT) in the development of this disease has also been increasingly raised. To date, the appearance of EoE in the course of OIT is an absolute indication for discontinuation of this procedure; however, other therapeutic options that do not require termination of this procedure are increasingly being advocated. Unfortunately, our knowledge of EoE is full of gaps and requires numerous studies to fill in the missing elements of the pathogenesis and clinic of the described disease.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"16 4","pages":"362-367"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global burden of five major types of gastrointestinal cancer. 全球五大类型胃肠道癌症负担。
IF 1.7
Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-07-26 DOI: 10.5114/pg.2024.141834
Arjun Singh
{"title":"Global burden of five major types of gastrointestinal cancer.","authors":"Arjun Singh","doi":"10.5114/pg.2024.141834","DOIUrl":"10.5114/pg.2024.141834","url":null,"abstract":"<p><p>Gastrointestinal (GI) cancers cause major global morbidity and mortality, with over 5 million new cases and 3.5 million deaths in 2020. The most prevalent GI malignancies are colorectal, gastric, liver, oesophageal, and pancreatic cancers. Marked geographic variations exist, with high incidence in developed regions contrasting with high mortality in developing areas. These patterns reflect disparities in risk factors and cancer control capacities. However, GI cancer incidence is rising with economic growth and lifestyle changes. Poor prognosis and increasing burden underscore the critical need for expanded prevention and research. This review examines global epidemiology, risks, prevention, detection, treatment, and priorities for common GI cancers. Controlling the toll of GI malignancies requires coordinated global actions across prevention, screening, treatment access, and research. Key priorities include vaccination, reducing modifiable risks, improving screening, expanding care access, and advancing prevention/therapy research. Global commitments to evidence-based interventions and knowledge sharing are vital to curb the GI cancer epidemic.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 3","pages":"236-254"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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