Przegla̜d Gastroenterologiczny最新文献

{"title":"Relationship between <i>Helicobacter pylori</i> infection and gastroesophageal reflux disease.","authors":"Seda Yılmaz, Kadir Gisi, Ali Cetinkaya, Bulent Kantarceken, Harun Ciralik","doi":"10.5114/pg.2024.145379","DOIUrl":"10.5114/pg.2024.145379","url":null,"abstract":"<p><strong>Introduction: </strong>Gastroesophageal reflux disease (GERD) is a common disease that negatively affects the quality of life, and its pathophysiology is multifactorial.</p><p><strong>Aim: </strong>Our study aims to investigate the relationship between histological and topographic characteristics of <i>Helicobacter pylori</i> (<i>H. pylori</i>) gastritis and the symptoms, presence, and severity of oesophagitis in patients with reflux symptoms.</p><p><strong>Material and methods: </strong>The symptoms, demographic data, and physical examination results of the patients admitted with gastrointestinal complaints were recorded and oesophagogastroduodenoscopies were performed. Biopsies were taken from the antrum and corpus.</p><p><strong>Results: </strong>Of the 171 patients, 113 were in the reflux group and 58 were in the non-reflux group. 103 (60%) of the patients were female and 68 (40%) were male. The mean age was 40 ±14 years in the GERD group and 49 ±16 years in the non-reflux group. There were no statistically significant differences between both groups in terms of endoscopic results or the presence and degree of oesophagitis. The total <i>H. pylori</i> frequency was found to be 73%; 75% in the GERD group and 69% in the non-reflux group. There was no significant relationship between the presence and degree of reflux oesophagitis. Chronic inflammation and neutrophil activity were higher in the antrum and corpus in the <i>H. pylori</i>-positive group, and gland atrophy was detected more frequently in the antrum in the <i>H. pylori</i>-negative group.</p><p><strong>Conclusions: </strong>The histological type of gastritis caused by <i>H. pylori</i> rather than the presence of <i>H. pylori</i> may be associated with GERD.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"16 4","pages":"423-427"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of artificial intelligence and image processing in the diagnosis, treatment, and prognosis of liver cancer: a narrative-review.","authors":"Platon Dimopoulos, Admir Mulita, Andreas Antzoulas, Sylvain Bodard, Vasileios Leivaditis, Ioanna Akrida, Nikolaos Benetatos, Konstantinos Katsanos, Christos-Nikolaos Anagnostopoulos, Francesk Mulita","doi":"10.5114/pg.2024.143147","DOIUrl":"10.5114/pg.2024.143147","url":null,"abstract":"<p><p>Artificial intelligence (AI) and image processing are revolutionising the diagnosis and management of liver cancer. Recent advancements showcase AI's ability to analyse medical imaging data, like computed tomography scans and magnetic resonance imaging, accurately detecting and classifying liver cancer lesions for early intervention. Predictive models aid prognosis estimation and recurrence pattern identification, facilitating personalised treatment planning. Image processing techniques enhance data analysis by precise segmentation of liver structures, fusion of information from multiple modalities, and feature extraction for informed decision-making. Despite progress, challenges persist, including the need for standardised datasets and regulatory considerations.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 3","pages":"221-230"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastric cancer in Ukraine: epidemiologic data and its nosological structure between 2003 and 2020.","authors":"Yevgen O Chernov, Valeriia Haysanovska, Olha V Makarenko","doi":"10.5114/pg.2024.134840","DOIUrl":"10.5114/pg.2024.134840","url":null,"abstract":"<p><strong>Introduction: </strong>Gastric cancer is one of the world's leading causes of death due to oncological diseases. Gastric cancer comprises a diverse group of diseases that includes several oncological units.</p><p><strong>Aim: </strong>To analyse the nosological structure of epidemiological data related to gastric cancer in Ukraine and compare it with global trends from 2003 to 2020.</p><p><strong>Material and methods: </strong>The data were retrieved from the National Cancer Registry of Ukraine and analysed using MedCalc for Windows, version 20.218 (MedCalc Software, Ostend, Belgium).</p><p><strong>Results: </strong>Eight forms of gastric cancer were diagnosed every year. The lowest incidence rate was in 2020, with 8.99 per 100,000 people/year. This was a 33.71% drop compared to 2005 (p < 0.0001). Adenocarcinoma constituted the largest part of the cases over the 2003 to 2020 period: 96.38% (95% CI: 95.02-97.05%). All the other types of gastric cancer together comprised 2.97% (95% CI: 2.34-3.76%) of the cases. The number of adenocarcinoma cases as well as its incidence rate decreased in 2003-2020 in Ukraine. The incidence rate of all types of gastric cancer was seen to decrease over the 2003-2020 timeframe in Ukraine. Adenocarcinoma was the leading form of gastric cancer in the country, and other types were uncommon in both Ukraine and the rest of the world. There was a change in the incidence rates of the other forms of gastric cancer, but those incidences did not notably affect the structure of the epidemiological data.</p><p><strong>Conclusions: </strong>The total number of cases of gastric cancer, as well as its incidence rate, decreased in Ukraine from 2003 to 2020. This situation corresponds with global tendencies.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"16 4","pages":"428-433"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing surgical prehabilitation through microbiota modulation.","authors":"Wojciech Marlicz, Grażyna Rydzewska","doi":"10.5114/pg.2024.145831","DOIUrl":"10.5114/pg.2024.145831","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"16 4","pages":"345-346"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic management of bleeding ectopic varices: multicentric retrospective case series.","authors":"Mohamed Ali El-Nady, Mahmoud Wahba, Oussama Ebada, Mamdouh Gabr, Kareem Essam, Abeer Abdellatef, Mohammed Ewid, Hyam Fathy, Mazen Naga, Ahmed Altonbary","doi":"10.5114/pg.2023.130201","DOIUrl":"10.5114/pg.2023.130201","url":null,"abstract":"<p><strong>Introduction: </strong>Portal hypertension is a common complication of liver cirrhosis. Varices are dilated collaterals that develop as a result of portal hypertension at the level of the porto-systemic connections and can cause a shift in the blood flow from high to low pressure. Common locations for porto-systemic shunts are the lower oesophagus and the gastric fundus. Ectopic varices are defined as dilated tortuous veins located at unusual sites other than the gastro-oesophageal junction.</p><p><strong>Aim: </strong>This research aimed to study the endoscopic assessment of ectopic varices as well as necessary haemostatic interventions to our best knowledge. Also, to perform a review of the literature to compare our results to the most recent available data.</p><p><strong>Material and methods: </strong>Our group extracted endoscopic reports of patients presenting to the emergency department with evidence of recent GI bleeding in whom ectopic varices were identified. We reported all interventions or procedures needed, details of hospitalization, radiological and laboratory results, as well as follow-up charts.</p><p><strong>Results: </strong>Our study included 95 patients presenting to the emergency department with evidence of active GI bleeding. Ectopic varices were identified as the source of bleeding in 28 cases. Bleeding from duodenal varices was found in 17 patients and rectal varices in 9 patients. Endoscopic management was used for all cases with active bleeding. Rebleeding from ectopic varices was found in 5 cases, for whom interventional radiology was performed. All cases with rebleeding were duodenal varices. Early mortality occurred in 3 cases after re-intervention.</p><p><strong>Conclusions: </strong>Our study describes a series of patients with ectopic varices discovered upon emergency endoscopy. Rectal varices were the most commonly found in our series. Bleeding and the need for re-intervention is more common in duodenal varices.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"1 1","pages":"271-276"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of risk factors of <i>Clostridioides difficile</i> infection in patients with inflammatory bowel disease.","authors":"Alicja Jakubowska, Dorota Szydlarska, Grażyna Rydzewska","doi":"10.5114/pg.2024.143145","DOIUrl":"10.5114/pg.2024.143145","url":null,"abstract":"<p><strong>Introduction: </strong><i>Clostridioides difficile</i> infection (CDI) is one of the most important challenges in contemporary gastroenterology. However, data from CDI studies are sometimes contradictory.</p><p><strong>Aim: </strong>To analyse the risk factors for CDI in patients with inflammatory bowel disease (IBD).</p><p><strong>Material and methods: </strong>This is a retrospective analysis of the medical records of 204 patients (77 IBD with CDI, 50 with IBD without CDI, and a control group of 77) hospitalised in a referral centre in Warsaw. Data were entered and analysed by using univariate logistic regression models.</p><p><strong>Results: </strong>Patients with IBD and CDI had significantly longer hospitalisation time than patients with IBD without CDI. The population of patients with CDI and IBD was statistically significantly younger (<i>p</i> < 0.001). Patients with IBD and CDI had a lower body mass index (<i>p</i> < 0.001) and were more often treated with antibiotics (<i>p</i> < 0.001). Prior antibiotic use (< 1 month) was a risk factor for CDI (<i>p</i> = 0.003). Lower body mass index (<i>p</i> < 0.001) and lower levels of albumins (<i>p</i> = 0.036) were strong risk factors for CDI in the study group. Additional risk factors were young age (<i>p</i> < 0.001), length of hospitalisation (<i>p</i> = 0.001), treatment with glucocorticosteroids (<i>p</i> = 0.001), immunosuppressive treatment (<i>p</i> = 0.001), and gastritis and/or duodenitis (<i>p</i> = 0.002). The study did not confirm that proton pump inhibitors or biologic treatment affected the risk of CDI.</p><p><strong>Conclusions: </strong>The risk factors for CDI in patients with IBD include younger age, female gender, low body mass index and hypoalbuminaemia, use of thiopurines, antibiotics, and glucocorticosteroids, prolonged hospitalisation, and gastritis and/or duodenitis.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 3","pages":"277-283"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial profile of biliary tract infection in patients undergoing therapeutic endoscopic retrograde cholangiopancreatography (ERCP), and baseline risk factors predicting microbial growth and post-ERCP cholangitis.","authors":"Hina Ismail, Raja Taha Yaseen Khan, Syed Mudassir Laeeq, Zain Majid, Abbas Ali Tasneem, Farina M Hanif, Nasir Hasan Luck","doi":"10.5114/pg.2024.136226","DOIUrl":"10.5114/pg.2024.136226","url":null,"abstract":"<p><strong>Introduction: </strong>Stasis of bile flow can result in microbial colonization of the biliary tree. Cholangitis is a common adverse event linked to endoscopic retrograde cholangiopancreatography (ERCP).</p><p><strong>Aim: </strong>To establish the bacterial profiles isolated from the bile sample and to evaluate the pre-ERCP risk factors predicting the microbial growth and development of post-ERCP cholangitis (PEC).</p><p><strong>Material and methods: </strong>This was a prospective cohort study, which was conducted at the Department of Hepato-gastroenterology, SIUT from 1 January 2021 to 31 December 2021. Patients of either gender undergoing index ERCP procedure were included in the study. All the patients underwent ERCP, and bile culture (BC) aspirated immediately after cannulation was achieved prior to the contrast injection. There were 2 outcome variables. One was the presence or absence of organisms in bile culture, and the second one was the development of PEC.</p><p><strong>Results: </strong>The total number of patients was 280. Bile culture was positive in 195 (69.6%) patients, and post-ERCP cholangitis developed in 187 (66.8%) patients. The most common organism in BC was <i>Escherichia coli</i> (<i>E. coli</i>), in 82 (42%) patients. History of jaundice, abdominal pain, and weight loss on admission along with ERCP performed for common bile duct (CBD) stricture were independent predictors of positive BC and PEC, while advanced age was an additional risk factor for PEC.</p><p><strong>Conclusions: </strong>Microbial profile and risk factors for positive BC and PEC were evaluated. Advanced age, pre-operative jaundice, and prolonged biliary stasis are the independent risk factors for these conditions.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 3","pages":"296-302"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foreign body ingestion in children attending Rapareen Teaching Hospital: a single-centre experience.","authors":"Dler Nooruldeen Chalabi","doi":"10.5114/pg.2023.130200","DOIUrl":"10.5114/pg.2023.130200","url":null,"abstract":"<p><strong>Introduction: </strong>Ingestion of foreign bodies is a significant problem among children, which necessitates early intervention and may lead to serious morbidity and even mortality.</p><p><strong>Aim: </strong>To estimate the pattern of foreign body ingestion among children and identify the role of management and its outcomes in relation to the type and site of foreign bodies.</p><p><strong>Material and methods: </strong>Our study was carried out on patients who attended the Emergency Department of the Rapareen Teaching Hospital for Paediatrics in Erbil city and were referred to the Paediatric Gastroenterology Unit during between March 2019 and January 2023. All clinical and demographic data were entered and then analysed using SPSS.</p><p><strong>Results: </strong>Fifty-four patients visited or were admitted to the Rapareen Hospital Emergency Department with a history of ingestion of foreign bodies, with a median age of 4 years (mean age: 4.14 ±2.15 years) and a nearly equal male-to-female ratio (1.16 : 1). Most of the foreign bodies were radiopaque, and the majority were located in the oesophagus at the time of initial presentation. Disc batteries (27.8%) were the commonest foreign body, followed by coins (20.4%), of which 66.7% were retrieved endoscopically, while 4 patients needed surgical intervention. Cross-tabulation reveals a significant association between the site of materials and the early presentation, type of object, and outcome. Also, a significant association was established between the type of foreign body and gender, age, time of presentation, and outcome.</p><p><strong>Conclusions: </strong>The button battery was the most common foreign body ingested among the children, and the majority were located in the oesophagus and extracted by endoscopy.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"1 1","pages":"284-289"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of an idiopathic adult ileocolic intussusception.","authors":"Platon Dimopoulos, Ioanna Akrida, George-Pappas Gogos, Vasileios Leivaditis, Georgios-Ioannis Verras, Konstantinos Tasios, Andreas Antzoulas, Vasiliki Garantzioti, Nikolas Drakos, Francesk Mulita","doi":"10.5114/pg.2024.138804","DOIUrl":"https://doi.org/10.5114/pg.2024.138804","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 2","pages":"217-219"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of biotechnologies in the treatment of haemorrhoidal disease and optimisation of patient management.","authors":"Dinara Nuspekova, Aidos Doskaliyev, Auyeskhan Dzhumabekov, Khabibulla Akilov, Aina Dossan","doi":"10.5114/pg.2024.139517","DOIUrl":"https://doi.org/10.5114/pg.2024.139517","url":null,"abstract":"<p><strong>Introduction: </strong>Haemorrhoidal disease is one of the most common nowadays. It is often associated with a sedentary lifestyle. The leading cause of its development is also a functional disorder of the intestine and chronic constipation. To date, there is a steady growth rate of this disease, leading to its \"rejuvenation\". The current stage of development indicates the need for further improvement of surgical treatment and optimisation of patient management methods and the creation of uniform standards of care for this contingent of patients.</p><p><strong>Aim: </strong>To evaluate the clinical effectiveness of the use of platelet-rich plasma therapy and the biologically active substance \"ozoyl\" in the treatment of haemorrhoidal disease.</p><p><strong>Material and methods: </strong>The main group included 100 patients with chronic haemorrhoids who were operated on in the period from March 2021 to March 2022. For this group, autoplasma was used during surgery, and an ozoyl-based drug in the postoperative period. The remaining 100 participants of this study, assigned to the control group, underwent a conventional haemorrhoidectomy operation and standard patient management using a hydrophilic ointment based on chloramphenicol.</p><p><strong>Results: </strong>After the conducted clinical studies, it was established that in the main group, the pain syndrome decreased by about 30%, considering the period from the first day of the postoperative period compared to the control group. The postoperative wound healed in the main group in the third week after the operation, unlike the control group, in which this event was noted in the fourth week. The patients did not complain during the examination 3 months later.</p><p><strong>Conclusions: </strong>This study is of practical significance because haemorrhoidal disease today has a high prevalence, and an integrated approach is required for the treatment of such patients. Ozoyl is a powerful cell and tissue repairer.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 2","pages":"127-134"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}