Przegla̜d Gastroenterologiczny最新文献

{"title":"Crohn's disease exacerbation or Dunbar syndrome?","authors":"Danuta Owczarek, Miłosz Błonski","doi":"10.5114/pg.2026.164951","DOIUrl":"10.5114/pg.2026.164951","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 3","pages":"391-393"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haematological features of Iraqi patients suffering from inflammatory bowel diseases.","authors":"Noor Zuhair Bakheet","doi":"10.5114/pg.2026.164971","DOIUrl":"10.5114/pg.2026.164971","url":null,"abstract":"<p><strong>Introduction: </strong>One of the most common laboratory tests in medicine is a complete blood count (CBC), which provides information about the size and quantity of circulating blood cells. CBC results are routinely used to evaluate acute or chronic inflammation and infection.</p><p><strong>Aim: </strong>This study aims to identify differences in haematological features (including cell count, red cell indices, platelet count, and blood composite results) between genders in patients with inflammatory bowel disease (IBD), and to investigate whether these differences are related to disease activity and anaemia.</p><p><strong>Material and methods: </strong>One hundred blood specimens were divided into 4 groups. The 1^st and 2^nd groups were healthy controls including 25 specimens from males (C-M group) and 25 specimens from females (C-F group). The 3^rd and 4^th groups were from patients with IBD and included 25 specimens from males (IBD-M group) and 25 specimens from females (IBD-F group). Automated haematology analysers were used to analyse whole blood specimens for CBC in all patients and controls. Measured parameters included blood leukocytes and differentials (neutrophil, lymphocyte, monocyte, eosinophil, and basophil), blood composite scores (N/L ratio, P/L ratio, M/L ratio, SIRI), PLT, PCT, RBCs, HGB, HCT, RDW, and red blood indices (MCV, MCH, MCHC).</p><p><strong>Results: </strong>There was a significant difference (<i>p</i> < 0.05) between patients with IBD and controls. We demonstrated higher levels in patients with IBD of blood leukocytes and differentials, blood composite scores, PLT, PCT, and RDW. While lower levels of lymphocytes, RBCs, HBG, HCT, and red blood indices were observed in the IBD-M and IBD-F groups, compared with the C-M and C-F groups. On the other hand, a significant difference (<i>p</i> < 0.05) was seen between genders of patients with IBD; the increase ratio was higher in females (WBC, neutrophil, monocyte, eosinophil, basophil, PLT, PCT, RDW) than in males, while the decrease ratio was lower in females (lymphocyte, RBCs, HBG, MCV, HCT) than in males, except MCH and MCHC.</p><p><strong>Conclusions: </strong>We found that haematological features in patients with IBD differ between the sexes and are associated with disease activity and the presence of anaemia. These features may be proposed as alternative biomarkers of the disease and could be used in clinical practice.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 3","pages":"340-346"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking the self-care program for cholecystectomy patients from global imperatives for quality of life (QoL) and prevention of postoperative complications.","authors":"Alaa H Hermis, Zainalabideen Y Jumaa, Dergham M Hameed, Burhan Hadi, Karrar N Abd Al Jaleel, Mustafa K Jawad, Sadiq S H Al-Salih, Rehab F Hassan, Sajjad S Salman, Salim K Hajwal","doi":"10.5114/pg.2026.161870","DOIUrl":"10.5114/pg.2026.161870","url":null,"abstract":"<p><strong>Introduction: </strong>Knowledge of self-care is an important index for evaluating the outcomes of treatment with cholecystectomy. In addition, teaching self-care encourages persons with cholecystectomy to increase self-efficacy.</p><p><strong>Aim: </strong>To identify the influence of socio-demographic characteristics in the application of self-care education on knowledge of patients with cholecystectomy.</p><p><strong>Material and methods: </strong>This quasi-experimental study was conducted in surgical wards at AL-Diwaniyah hospitals and the Gastrointestinal Centre from 12 November 2022 to 15 March 2023. The study used a purposive sample of 60 patients, selected based on a 95% confidence level and a 5% margin of error. The inclusion criteria involved patients with benign gallbladder conditions undergoing cholecystectomy, who were conscious and willing to participate, while those with cancer were excluded to reduce confounding variables. The participants were divided into a control group of 30 patients receiving routine care and a study group of 30 patients undergoing an educational program on self-care after surgery. The utilised instrument included sociodemographic questions to gather relevant data. The study comprised 2 parts: the first focused on sociodemographic characteristics using 10 multiple-choice questions developed by the researcher, covering age, gender, marital status, weight, income, education, residence, occupation, and family history of gallbladder removal. The second part assessed patient knowledge of self-care following cholecystectomy through a questionnaire of 24 items, constructed from literature reviews and expert opinions. Responses were scored as 0 for incorrect and 1 for correct answers. The effectiveness of an educational program on self-care knowledge was evaluated 2 weeks after a lecture, with follow-up in surgical consultations at hospitals. A post-test was conducted between 10 January and 15 March 2023, and data analysis was performed using SPSS version 24.0, applying <i>t</i>-tests, ANOVA, and descriptive statistics.</p><p><strong>Results: </strong>Study findings revealed that there were only 2 significant differences between the study group knowledge about cholecystectomy and their residence at post-test (<i>p</i> = 0.005), and with their family history of complications following cholecystectomy (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>This study found that an educational program is an effective way to improve patients' knowledge about self-care after cholecystectomy, which can lead to better outcomes, decreased complications, and improved patient satisfaction and quality of life. It is recommended that healthcare providers consider implementing such these programs to improve the quality of care provided to patients.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 2","pages":"185-190"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148550224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoglycaemia in a patient with huge hepatocellular carcinoma responsive to chemoembolisation and tumour resection.","authors":"Helen Bolanaki, Francesk Mulita, Athanasia Mitsala, Anastasios Zorbalas, Ioannis Tzimagiorgis, Anastasios J Karayiannakis","doi":"10.5114/pg.2026.160318","DOIUrl":"10.5114/pg.2026.160318","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 1","pages":"103-107"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic pancreatitis associated with genetic mutation and drug-resistant epilepsy.","authors":"Magdalena W Koczyńska, Wojciesko Ewa Małecka-, Ludomir Stefańczyk","doi":"10.5114/pg.2026.160312","DOIUrl":"10.5114/pg.2026.160312","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 1","pages":"115-118"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastroenterological disorders in inborn errors of immunity. Part 2 A. Overview of selected diseases.","authors":"Katarzyna Napiórkowska-Baran, Paweł Treichel, Kinga Koperska, Oliwia Kudrej, Natalia Mućka, Alicja Rajewska, Adam Wawrzeńczyk, Zbigniew Bartuzi","doi":"10.5114/pg.2026.160370","DOIUrl":"10.5114/pg.2026.160370","url":null,"abstract":"<p><p>Gastrointestinal symptoms are common in patients with inborn errors of immunity and may serve as early indicators of immunological dysregulation. This review focuses on selected diseases of the IUIS classification, where gastrointestinal manifestations play a crucial role. The analysis is based on a wide range of scientific literature addressing clinical, diagnostic, and therapeutic aspects, emphasising the need for a multidisciplinary approach in patient management.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 1","pages":"25-28"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of the approach of Polish gastroenterologists and surgeons to the diagnosis and treatment of complex cases of Crohn's disease-related perianal fistulas.","authors":"Piotr Eder, Tomasz Banasiewicz, Joanna Głażewska, Jarosław Reguła, Grażyna Rydzewska, Grzegorz Wallner, Adam J Dziki","doi":"10.5114/pg.2026.165045","DOIUrl":"10.5114/pg.2026.165045","url":null,"abstract":"<p><strong>Introduction: </strong>Crohn's disease (CD) is a chronic, relapsing inflammatory disorder that can affect any part of the gastrointestinal tract. CD-related perianal fistulas are difficult to treat and require coordinated surgical-medical care.</p><p><strong>Aim: </strong>The aim of this study was to describe how Polish gastroenterologists and surgeons diagnose and manage complex perianal fistulas associated with Crohn's disease during initial and subsequent lines of treatment, including surgical care.</p><p><strong>Material and methods: </strong>A nationwide retrospective analysis was conducted, including a review of the medical records of 80 patients with complex perianal fistulas after failure of standard therapy, and surveys of 27 gastroenterologists representing the majority of centres involved in the B.32 programme and 12 colorectal surgeons (February-March 2023).</p><p><strong>Results: </strong>In surveys, clinicians estimated that about 20% of their CD patients currently had a perianal fistula, while another 20% had a history of one; 24% of first fistulas reportedly preceded CD diagnosis, 36% occurred within 3 years, and 13% after > 10 years. Magnetic resonance imaging was the most frequently used imaging modality for complex fistulas. In the chart cohort, initial (\"standard\") therapy most often combined azathioprine, antibiotics, metronidazole, and glucocorticoids (median duration 13 weeks). After failure, 80% received combined surgical-medical care; 91% received biologics as first or second post-failure therapy (infliximab <i>n</i> = 51/80, 63.8%; adalimumab <i>n</i> = 13/80, 16.3%; vedolizumab <i>n</i> = 3/80, 3.8%; ustekinumab <i>n</i> = 1/80, 1.3%). Surgeons most commonly performed abscess drainage, seton placement, and fistulectomy. Reported barriers included long waits for MRI and limited access to centres specialising in the treatment of perianal fistulas.</p><p><strong>Conclusions: </strong>Management patterns vary and interdisciplinary coordination is inconsistent; structured care pathways and multidisciplinary clinics are needed in Poland.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 3","pages":"347-356"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term results of treatment with direct-acting antivirals, corticosteroids, plasmapheresis, and rituximab in a patient with cryoglobulinaemic vasculitis and HCV infection: a case report and review of the literature.","authors":"Eleni Theodoropoulou, Charikleia Gakiopoulou, Marina Papadaki, Spyridon Vrakas","doi":"10.5114/pg.2026.164952","DOIUrl":"10.5114/pg.2026.164952","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 3","pages":"402-405"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remission duration according to dietary adherence in paediatric mild to moderate Crohn's disease treated with CDED + PEN.","authors":"Anna Wiernicka, Izabela Jałocha, Małgorzata Garwolińska","doi":"10.5114/pg.2026.162020","DOIUrl":"10.5114/pg.2026.162020","url":null,"abstract":"<p><strong>Introduction: </strong>The Crohn's Disease Exclusion Diet (CDED) combined with partial enteral nutrition (PEN) is a dietary therapy developed to induce and maintain remission in patients with Crohn's disease.</p><p><strong>Aim: </strong>The aim of study was to evaluate the duration of clinical remission in paediatric patients with mild to moderate Crohn's disease undergoing a Crohn's Disease Exclusion Diet (CDED) combined with partial enteral nutrition (PEN), stratified by degree of dietary adherence.</p><p><strong>Material and methods: </strong>A retrospective, single-centre observational study was conducted with the participation of paediatric patients who underwent CDED + PEN treatment in the period from June 2019 to June 2025. Twelve-month clinical follow-up was available in 41 subjects. The following were assessed: BMI-SDS index (group 6-17 years), erythrocyte sedimentation rate, C-reactive protein, faecal calprotectin, Pediatric Crohn's Disease Activity Index (PCDAI) scale score, and adherence. Time to relapse was analysed.</p><p><strong>Results: </strong>Data from 54 patients aged 6-17 years were analysed. Mean baseline PCDAI was 15.47 ±12.44. Clinical remission (PCDAI < 10) was achieved in 69% at week 6 and in 77% at week 12. The median time to relapse was 8.2 months. A statistically significant factor influencing the duration of remission was identified. The median remission time was 11.97 months (IQR: 7.60-25.98; mean: 18.75 ±16.18) in patients with adherence ≥ 80% (<i>n</i> = 17) and 5.63 months (IQR: 4.97-8.03; mean: 6.88 ±4.02) with adherence < 80% (<i>n</i> = 10). The mean difference between groups was 11.9 months (95% CI: 3.3-20.5); Welch's test <i>p</i> = 0.009. An <i>F</i>-test confirmed unequal variances (<i>p</i> = 0.0002).</p><p><strong>Conclusions: </strong>Suboptimal adherence remains a key modifiable predictor of relapse. Data support consideration of CDED + PEN as a viable long-term strategy in motivated families and underscore the pivotal role of the dietitian in monitoring adherence and nutritional status.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 2","pages":"166-170"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148550223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual origin of a pancreatic head mass.","authors":"Idris Kurt, Yalçın Taymez, Görkem Karadağ, Bahar Kandemir, Türkay Demirbozan, Hasan C Ümit, Hüseyin A Tezel, Ali R Soylu","doi":"10.5114/pg.2026.160315","DOIUrl":"10.5114/pg.2026.160315","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"21 1","pages":"111-114"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}